Enhanced Anticancer Therapy Mediated by Specialized Liposomes

It has been a central aim of experimental and clinical therapeutics to deliver therapeutic agents as close as possible to, or if possible within, a diseased cell. Such targeting achieves two major aims of drug delivery, the maximum dose of therapeutic agent to the diseased cell and avoidance of uptake by and, usually, accompanying side‐effects to normal, healthy cells.

[1]  P. Mougin,et al.  Gene transfer into subcultured endometrial cells using lipofection. , 1996, BioTechniques.

[2]  H. Kijima,et al.  Tissue-specific expression of an anti-ras ribozyme inhibits proliferation of human malignant melanoma cells. , 1996, Nucleic acids research.

[3]  I. Ahmad,et al.  Antibody-targeted delivery of doxorubicin entrapped in sterically stabilized liposomes can eradicate lung cancer in mice. , 1993, Cancer research.

[4]  D. Thompson,et al.  Triggerable plasmalogen liposomes: improvement of system efficiency. , 1996, Biochimica et biophysica acta.

[5]  Y. Kaneda,et al.  Fusigenic viral liposome for gene therapy in cardiovascular diseases. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[6]  J. Behr,et al.  Gene transfer with synthetic cationic amphiphiles: prospects for gene therapy. , 1994, Bioconjugate chemistry.

[7]  R. Leventis,et al.  Interactions of cationic lipid vesicles with negatively charged phospholipid vesicles and biological membranes. , 1988, Biochemistry.

[8]  Joachim O. Rädler,et al.  Structure of DNA-Cationic Liposome Complexes: DNA Intercalation in Multilamellar Membranes in Distinct Interhelical Packing Regimes , 1997, Science.

[9]  J. Hagstrom,et al.  pH-sensitive, cationic liposomes: A new synthetic virus-like vector , 1996, Nature Biotechnology.

[10]  M. Nakanishi,et al.  Introduction of plasmid DNA and nuclear protein into cells by using erythrocyte ghosts, liposomes, and Sendai virus. , 1993, Methods in enzymology.

[11]  M. Fonseca,et al.  Coating liposomes with collagen (Mr 50,000) increases uptake into liver. , 1996, Biochimica et biophysica acta.

[12]  M. Shono,et al.  Kinetic analysis of endocytosis and intracellular fate of liposomes in single macrophages. , 1995, Journal of biochemistry.

[13]  R. Morishita,et al.  In vivo identification of a negative regulatory element in the mouse renin gene using direct gene transfer. , 1995, The Journal of clinical investigation.

[14]  D. Hadjiminas,et al.  Construction of transferrin-coated liposomes for in vivo transport of exogenous DNA to bone marrow erythroblasts in rabbits. , 1986, Experimental cell research.

[15]  D. Lasič,et al.  LIPOSOMES AND LIPIDIC PARTICLES IN GENE THERAPY , 1996 .

[16]  G Blomqvist,et al.  Kinetic analysis. , 1991, Wiener klinische Wochenschrift.

[17]  G Gregoriadis,et al.  Engineering liposomes for drug delivery: progress and problems. , 1995, Trends in biotechnology.

[18]  Y. Okada Sendai virus-induced cell fusion. , 1993, Methods in enzymology.

[19]  T. Otsuka,et al.  Hyperthermia induces apoptosis in malignant fibrous histiocytoma cells in vitro , 1996, International journal of cancer.

[20]  S. Kennel,et al.  Lipid composition is important for highly efficient target binding and retention of immunoliposomes. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[21]  M. Shinkai,et al.  Antibody‐conjugated magnetoliposomes for targeting cancer cells and their application in hyperthermia , 1995, Biotechnology and applied biochemistry.

[22]  M. Lapidot,et al.  Fusion-mediated microinjection of liposome-enclosed DNA into cultured cells with the aid of influenza virus glycoproteins. , 1990, Experimental cell research.

[23]  R. Perez-soler,et al.  Liposomes in the treatment of malignancy: a clinical perspective. , 1992, Critical reviews in oncology/hematology.

[24]  J. Zabner,et al.  Optimization of cationic lipid-mediated gene transfer to airway epithelia. , 1995, The American journal of physiology.

[25]  J. Isner,et al.  Liposome-mediated gene transfer into human vascular smooth muscle cells. , 1994, Circulation.

[26]  J. Glenn,et al.  Delivery of liposome-encapsulated RNA to cells expressing influenza virus hemagglutinin. , 1993, Methods in enzymology.

[27]  T. Curiel,et al.  Optimization of gene transfer using cationic lipids in cell lines and primary human CD4+ and CD34+ hematopoietic cells. , 1995, BioTechniques.

[28]  H. Schreier,et al.  Pulmonary delivery of liposomes , 1993 .

[29]  L. Deftos,et al.  Importance of liposome complexing volume in transfection optimization. , 1996, BioTechniques.

[30]  D. Lasič,et al.  Doxorubicin in sterically stabilized liposomes , 1996, Nature.

[31]  M. Bally,et al.  Cationic lipid binding to DNA: characterization of complex formation. , 1996, Biochemistry.

[32]  C. McArdle,et al.  Abnormal vasculature of solid tumours: significance for microsphere-based targeting strategies. , 1991, International journal of radiation biology.

[33]  T. Allen,et al.  A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells. , 1995, Biochimica et biophysica acta.

[34]  F. Martin,et al.  Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon carcinoma. , 1992, Cancer research.

[35]  P. Low,et al.  Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[36]  B. A. French,et al.  Coronary restenosis and gene therapy. , 1994, Texas Heart Institute journal.

[37]  L. Huang,et al.  Biodistribution and immunotargetability of ganglioside-stabilized dioleoylphosphatidylethanolamine liposomes. , 1992, Biochimica et biophysica acta.

[38]  M. Spector,et al.  DNA Ordering on a Lipid Membrane , 1997, Science.

[39]  Joseph Zabner,et al.  Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid (*) , 1995, The Journal of Biological Chemistry.

[40]  G. Lázár,et al.  Targeting of liposomes to liver cells. , 1989, Horizons in biochemistry and biophysics.

[41]  J. Carmichael,et al.  Targeting solid tumours: challenges, disappointments, and opportunities , 1995 .

[42]  L. Huang,et al.  pH-sensitive immunoliposomes mediate target-cell-specific delivery and controlled expression of a foreign gene in mouse. , 1987, Proceedings of the National Academy of Sciences of the United States of America.