Congenital cataract following German measles in the mother. 1941.
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In Australia in the 1940s, Norman McAlister Gregg observed a connection between pregnant women who contracted the rubella virus, or German measles, and cataract formation in their children's eyes. Gregg published his findings in the 1941 article "Congenital Cataract following German Measles in the Mother" in Transactions of the Ophthalmological Society of Australia. In the article, Gregg analyzed seventy-eight cases of congenital cataracts and suggested that the mothers' environmental factors could cause birth defects [4], otherwise known as teratogenic effects. Gregg's paper on the teratogenic effects of an environmental agent, the rubella virus, changed the study of birth defects [4] to include viruses as potential causes or teratogens.
[1] C. Swan,et al. CONGENITAL DEFECTS IN INFANTS FOLLOWING INFECTIOUS DISEASES DURING PREGNANCY , 1943 .
[2] R. Hopesimpson. RUBELLA AND CONGENITAL MALFORMATIONS , 1944 .
[3] Rubella and Congenital Abnormalities , 1946, British medical journal.