Placental site trophoblastic tumor: A case report and literature review.

Here, we report a case of a placental site trophoblastic tumor (PSTT) in a 36-year-old Chinese woman 10 months after a normal pregnancy. Two months postpartum, the woman presented with abnormal vaginal discharge and her condition was overlooked by her local hospital. The woman did not receive further attention until a mass with a heterogeneous echo was found in an ultrasound examination eight months postpartum. The final diagnosis was confirmed by histological examinations in conjunction with immunohistochemical studies. Since the patient had potential risk factors, she was successfully treated with a hysterectomy and peri- and post-operative chemotherapy. The latest follow-up (16 months after diagnosis) was uneventful, and the patient exhibited no signs of recurrence or metastasis.

[1]  K. Hua,et al.  Retrospective analysis of the clinicopathologic and prognostic characteristics of stage I placental site trophoblastic tumor in China , 2015, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

[2]  M. Çaydere,et al.  A rare case of uterine rupture due to a placental site trophoblastic tumour in the rudimentary horn , 2015, Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology.

[3]  R. Edwards,et al.  Placental site trophoblastic tumor: Immunohistochemistry algorithm key to diagnosis and review of literature☆ , 2013, Gynecologic oncology case reports.

[4]  D. Hyman,et al.  Placental site trophoblastic tumor: analysis of presentation, treatment, and outcome. , 2013, Gynecologic oncology.

[5]  R. Coleman,et al.  Deaths from gestational trophoblastic neoplasia: any lessons to be learned? , 2012, The Journal of reproductive medicine.

[6]  A. Hashi,et al.  [Diagnosis and treatment of placental site trophoblastic tumor]. , 2012, Nihon rinsho. Japanese journal of clinical medicine.

[7]  A. Mcindoe,et al.  Placental site trophoblastic tumours and the concept of fertility preservation , 2012, BJOG : an international journal of obstetrics and gynaecology.

[8]  Jun Zhao,et al.  Fertility-Preserving Treatment in Young Patients With Placental Site Trophoblastic Tumors , 2012, International Journal of Gynecologic Cancer.

[9]  H. Buyukbayram,et al.  Two cases of placental site trophoblastic tumor. , 2011, Taiwanese journal of obstetrics & gynecology.

[10]  Jie-hua He,et al.  Placental site trophoblastic tumor: lymphatic spread and possible target markers. , 2010, Gynecologic oncology.

[11]  V. Fülöp,et al.  Placental site trophoblastic tumor , 2000, Pathology & Oncology Research.

[12]  N. Sebire,et al.  Prognostic markers and long-term outcome of placental-site trophoblastic tumours: a retrospective observational study , 2009, The Lancet.

[13]  D. Cao,et al.  Placental Site Trophoblastic Tumor in the Ovary of a Young Child with Isosexual Precocious Puberty , 2009, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

[14]  Piotr Paleń,et al.  Successful Treatment of Placental Site Trophoblastic Tumor in Twin Pregnancy without Hysterectomy , 2009, Tumori.

[15]  B. Piura,et al.  [Placental site trophoblastic tumor]. , 2007, Harefuah.

[16]  L. Cole,et al.  Management of gestational trophoblastic disease and other cases with low serum levels of human chorionic gonadotropin. , 2006, The Journal of reproductive medicine.

[17]  M. Wells,et al.  Placental site trophoblastic tumour: clinical features and management. , 2005, Gynecologic oncology.

[18]  H. Hoekstra,et al.  Placental site trophoblastic tumor in a late recurrence of a nonseminomatous germ cell tumor of the testis. , 2004, The American journal of surgical pathology.

[19]  I. McNeish,et al.  Twenty-five years' clinical experience with placental site trophoblastic tumors. , 2002, The Journal of reproductive medicine.

[20]  R. Berkowitz,et al.  Placental site trophoblastic tumor: a 17-year experience at the New England Trophoblastic Disease Center. , 2001, Gynecologic oncology.

[21]  Y. Soong,et al.  Prognostic factors and treatment for placental site trophoblastic tumor-report of 3 cases and analysis of 88 cases. , 1999, Gynecologic oncology.

[22]  R. Fisher,et al.  Management of placental site trophoblastic tumors. , 1998, The Journal of reproductive medicine.

[23]  L. Twiggs,et al.  Trophoblastic pseudotumor-evidence of malignant disease potential. , 1981, Gynecologic oncology.

[24]  R. Scully,et al.  Trophoblastic pseudotumor: a reappraisal. , 1981, The American journal of surgical pathology.

[25]  R. Scully,et al.  Trophoblastic pseudotumor of the uterus. An exaggerated form of “syncytial endometritis” simulating a malignant tumor , 1976, Cancer.