Long-term robustness of a T-cell system emerging from somatic rescue of a genetic block in T-cell development
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K. Schwarz | S. Ehl | S. Fuchs | T. Boehm | A. Frei | P. Fisch | C. Speckmann | S. Bakhtiar | P. Kury | M. Führer | Orlando B. Giorgetti | M. Lorenz
[1] F. Bushman,et al. Clonal tracking in gene therapy patients reveals a diversity of human hematopoietic differentiation programs. , 2020, Blood.
[2] B. Bengsch,et al. Use of Mass Cytometry to Profile Human T Cell Exhaustion , 2020, Frontiers in Immunology.
[3] T. Mora,et al. How many different clonotypes do immune repertoires contain? , 2019, bioRxiv.
[4] Eric J. Alm,et al. Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in highly public receptors , 2019, BMC Immunology.
[5] A. Fischer,et al. Somatic genetic rescue in Mendelian haematopoietic diseases , 2019, Nature Reviews Genetics.
[6] J. Bienkowska,et al. Model to improve specificity for identification of clinically-relevant expanded T cells in peripheral blood , 2019, PloS one.
[7] S. Fuchs,et al. High‐dimensional single‐cell proteomics analysis identifies immune checkpoint signatures and therapeutic targets in ulcerative colitis , 2019, European journal of immunology.
[8] Lai Guan Ng,et al. Dimensionality reduction for visualizing single-cell data using UMAP , 2018, Nature Biotechnology.
[9] F. Camargo,et al. Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis , 2018, Cell reports.
[10] David A. Williams,et al. T cell dynamics and response of the microbiota after gene therapy to treat X-linked severe combined immunodeficiency , 2018, Genome Medicine.
[11] M. Stratton,et al. Population dynamics of normal human blood inferred from somatic mutations , 2018, Nature.
[12] Yufeng Shen,et al. Quantifying size and diversity of the human T cell alloresponse. , 2018, JCI insight.
[13] P. Woll,et al. Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells , 2018, Nature.
[14] H. Robins,et al. Aging-related changes in human T-cell repertoire over 20years delineated by deep sequencing of peripheral T-cell receptors , 2017, Experimental Gerontology.
[15] P. Rinaldo,et al. A Droplet Digital PCR Method for Severe Combined Immunodeficiency Newborn Screening. , 2017, The Journal of molecular diagnostics : JMD.
[16] Wei Chen,et al. Polylox barcoding reveals haematopoietic stem cell fates realized in vivo , 2017, Nature.
[17] K. Sullivan,et al. The immune deficiency of chromosome 22q11.2 deletion syndrome , 2017, American journal of medical genetics. Part A.
[18] Lei Zhang,et al. Differences between germline and somatic mutation rates in humans and mice , 2017, Nature Communications.
[19] K. Schwarz,et al. A prospective study on the natural history of patients with profound combined immunodeficiency: An interim analysis , 2017, The Journal of allergy and clinical immunology.
[20] L. Steinmetz,et al. Human haematopoietic stem cell lineage commitment is a continuous process , 2017, Nature Cell Biology.
[21] Li Zhang,et al. 3D: diversity, dynamics, differential testing – a proposed pipeline for analysis of next-generation sequencing T cell repertoire data , 2017, BMC Bioinformatics.
[22] Hao Wu,et al. Characterization of T and B cell repertoire diversity in patients with RAG deficiency , 2016, Science Immunology.
[23] Mikhail Shugay,et al. Dynamics of Individual T Cell Repertoires: From Cord Blood to Centenarians , 2016, The Journal of Immunology.
[24] L. Notarangelo,et al. Human RAG mutations: biochemistry and clinical implications , 2016, Nature Reviews Immunology.
[25] A. Fischer,et al. Severe combined immunodeficiencies and related disorders , 2015, Nature Reviews Disease Primers.
[26] F. Staal,et al. Development of a diverse human T-cell repertoire despite stringent restriction of hematopoietic clonality in the thymus , 2015, Proceedings of the National Academy of Sciences.
[27] Mei Liu,et al. Longitudinal analysis of peripheral blood T cell receptor diversity in patients with systemic lupus erythematosus by next-generation sequencing , 2015, Arthritis Research & Therapy.
[28] William S. DeWitt,et al. Dynamics of the Cytotoxic T Cell Response to a Model of Acute Viral Infection , 2015, Journal of Virology.
[29] J. Calis,et al. Characterizing immune repertoires by high throughput sequencing: strategies and applications. , 2014, Trends in immunology.
[30] Christopher Baum,et al. A modified γ-retrovirus vector for X-linked severe combined immunodeficiency. , 2014, The New England journal of medicine.
[31] Richard A. Olshen,et al. Diversity and clonal selection in the human T-cell repertoire , 2014, Proceedings of the National Academy of Sciences.
[32] G. Crooks,et al. Human Lymphoid Development in the Absence of Common γ-Chain Receptor Signaling , 2014, The Journal of Immunology.
[33] Volker Rasche,et al. Cell competition is a tumour suppressor mechanism in the thymus , 2014, Nature.
[34] R. Emerson,et al. Using synthetic templates to design an unbiased multiplex PCR assay , 2013, Nature Communications.
[35] Susan M. Schlenner,et al. Thymus-autonomous T cell development in the absence of progenitor import , 2012, The Journal of experimental medicine.
[36] G. Driessen,et al. Paediatric Reference Values for the Peripheral T cell Compartment , 2011, Scandinavian journal of immunology.
[37] B. Smart. Stem-Cell Gene Therapy for the Wiskott-Aldrich Syndrome , 2011, Pediatrics.
[38] Kathryn L. Parsley,et al. Long-Term Persistence of a Polyclonal T Cell Repertoire After Gene Therapy for X-Linked Severe Combined Immunodeficiency , 2011, Science Translational Medicine.
[39] Joseph C. Sun,et al. Homeostatic proliferation generates long-lived natural killer cells that respond against viral infection , 2011, The Journal of experimental medicine.
[40] Christof von Kalle,et al. Stem-cell gene therapy for the Wiskott-Aldrich syndrome. , 2010, The New England journal of medicine.
[41] P. Pereira,et al. Cutting Edge: Thymic NK Cells Develop Independently from T Cell Precursors , 2010, The Journal of Immunology.
[42] J. D. Di Santo,et al. The intrathymic crossroads of T and NK cell differentiation , 2010, Immunological reviews.
[43] Abigail Wacher,et al. Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells. , 2009, Blood.
[44] U. Pannicke,et al. Clinical and immunologic consequences of a somatic reversion in a patient with X-linked severe combined immunodeficiency. , 2008, Blood.
[45] R. Zufferey,et al. Correlation between recent thymic emigrants and CD31+ (PECAM‐1) CD4+ T cells in normal individuals during aging and in lymphopenic children , 2007, European journal of immunology.
[46] Kathryn L. Parsley,et al. Successful reconstitution of immunity in ADA-SCID by stem cell gene therapy following cessation of PEG-ADA and use of mild preconditioning. , 2006, Molecular therapy : the journal of the American Society of Gene Therapy.
[47] Christine Kinnon,et al. Mutations in TNFRSF13B Encoding TACI Are Associated With Common Variable Immunodeficiency in Humans , 2006, Pediatrics.
[48] J. Dorfman,et al. Turnover and Proliferation of NK Cells in Steady State and Lymphopenic Conditions1 , 2004, The Journal of Immunology.
[49] W. Leonard. Cytokines and immunodeficiency diseases , 2001, Nature Reviews Immunology.
[50] I. Weissman,et al. Stem cells, cancer, and cancer stem cells , 2001, Nature.
[51] L. Bogatzki,et al. Naive T Cells Transiently Acquire a Memory-like Phenotype during Homeostasis-Driven Proliferation , 2000, The Journal of experimental medicine.
[52] V. Wahn,et al. Diversity, functionality, and stability of the T cell repertoire derived in vivo from a single human T cell precursor. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[53] A. Casrouge,et al. A Direct Estimate of the Human αβ T Cell Receptor Diversity , 1999 .
[54] R. Hockett,et al. T cell receptor gene deletion circles identify recent thymic emigrants in the peripheral T cell pool. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[55] M. Shlomchik,et al. A Shannon entropy analysis of immunoglobulin and T cell receptor. , 1997, Molecular immunology.
[56] U. Dirksen,et al. Atypical X-linked severe combined immunodeficiency due to possible spontaneous reversion of the genetic defect in T cells. , 1996, The New England journal of medicine.
[57] Mark M. Davis,et al. T-cell antigen receptor genes and T-cell recognition , 1988, Nature.
[58] Mark M. Davis,et al. Somatic recombination in a murine T-cell receptor gene , 1984, Nature.
[59] Cesare Baroni-Urbani,et al. Similarity of Binary Data , 1976 .
[60] V. Giudicelli,et al. IMGT(®) tools for the nucleotide analysis of immunoglobulin (IG) and T cell receptor (TR) V-(D)-J repertoires, polymorphisms, and IG mutations: IMGT/V-QUEST and IMGT/HighV-QUEST for NGS. , 2012, Methods in molecular biology.