Blood–brain Barrier: Structural Components and Function Under Physiologic and Pathologic Conditions

[1]  Howard E Gendelman,et al.  HIV-1 gp120 Compromises Blood–Brain Barrier Integrity and Enhance Monocyte Migration across Blood–Brain Barrier: Implication for Viral Neuropathogenesis , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[2]  M. Toborek,et al.  HIV-TAT Protein Upregulates Expression of Multidrug Resistance Protein 1 in the Blood–Brain Barrier , 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[3]  K. Kaibuchi,et al.  Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE). , 2006, Blood.

[4]  E. Kılıç,et al.  Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia , 2006, Nature Neuroscience.

[5]  R. Keep,et al.  Protein Kinase Cα-RhoA Cross-talk in CCL2-induced Alterations in Brain Endothelial Permeability* , 2006, Journal of Biological Chemistry.

[6]  D. Karussis,et al.  Neuroinflammation in multiple sclerosis: Evidence for autoimmune dysregulation, not simple autoimmune reaction , 2006, Clinical Neurology and Neurosurgery.

[7]  A. Naqvi,et al.  Rac1 leads to phosphorylation-dependent increase in stability of the p66shc adaptor protein: role in Rac1-induced oxidative stress. , 2005, Molecular biology of the cell.

[8]  E. Hansson,et al.  Astrocyte–endothelial interactions at the blood–brain barrier , 2006, Nature Reviews Neuroscience.

[9]  Char-Huei Lai,et al.  The critical component to establish in vitro BBB model: Pericyte , 2005, Brain Research Reviews.

[10]  P. Mcgeer,et al.  Inflammation, the complement system and the diseases of aging , 2005, Neurobiology of Aging.

[11]  N. Farman,et al.  Aldosterone and tight junctions: modulation of claudin-4 phosphorylation in renal collecting duct cells. , 2005, American journal of physiology. Cell physiology.

[12]  A. Ghorpade,et al.  Alcohol‐induced oxidative stress in brain endothelial cells causes blood‐brain barrier dysfunction , 2005, Journal of leukocyte biology.

[13]  A. Fagan,et al.  P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model. , 2005, The Journal of clinical investigation.

[14]  M. Toborek,et al.  Signaling Mechanisms of HIV-1 Tat-Induced Alterations of Claudin-5 Expression in Brain Endothelial Cells , 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[15]  D. Praticò.  Antioxidants and endothelium protection. , 2005, Atherosclerosis.

[16]  Wolfgang Löscher,et al.  Drug resistance in brain diseases and the role of drug efflux transporters , 2005, Nature Reviews Neuroscience.

[17]  F. Luscinskas,et al.  ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow. , 2005, Blood.

[18]  G. Rosenberg,et al.  Matrix metalloproteinases and free radicals in cerebral ischemia. , 2005, Free radical biology & medicine.

[19]  J. Liversidge,et al.  Leukocyte diapedesis in vivo induces transient loss of tight junction protein at the blood-retina barrier. , 2005, Investigative ophthalmology & visual science.

[20]  T. Davis,et al.  The Blood-Brain Barrier/Neurovascular Unit in Health and Disease , 2005, Pharmacological Reviews.

[21]  P. Grammas,et al.  HIV-1 gp120 Proteins Alter Tight Junction Protein Expression and Brain Endothelial Cell Permeability: Implications for the Pathogenesis of HIV-Associated Dementia , 2005, Journal of neuropathology and experimental neurology.

[22]  Donald W. Miller,et al.  Ethanol-induced activation of myosin light chain kinase leads to dysfunction of tight junctions and blood-brain barrier compromise. , 2005, Alcoholism, clinical and experimental research.

[23]  M. Toborek,et al.  HIV‐Tat protein induces P‐glycoprotein expression in brain microvascular endothelial cells , 2005, Journal of neurochemistry.

[24]  Wolfgang Löscher,et al.  Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases , 2005, Progress in Neurobiology.

[25]  S. Cole,et al.  Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. , 2005, Toxicology and applied pharmacology.

[26]  R. Keep,et al.  Monocyte Chemoattractant Protein-1 Regulation of Blood–Brain Barrier Permeability , 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[27]  M. Ryan,et al.  Occludin: structure, function and regulation. , 2005, Advanced drug delivery reviews.

[28]  Berislav V. Zlokovic,et al.  Neurovascular mechanisms of Alzheimer's neurodegeneration , 2005, Trends in Neurosciences.

[29]  Du Guanhua,et al.  Glucose Transporter 1, Distribution in the Brain and in Neural Disorders: Its Relationship With Transport of Neuroactive Drugs Through the Blood-Brain Barrier , 2005, Biochemical Genetics.

[30]  W. Löscher,et al.  Immunohistochemical Localization of P-glycoprotein in Rat Brain and Detection of Its Increased Expression by Seizures Are Sensitive to Fixation and Staining Variables , 2005, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[31]  P. Casey,et al.  Rap1 GTPase Inhibits Leukocyte Transmigration by Promoting Endothelial Barrier Function* , 2005, Journal of Biological Chemistry.

[32]  T. Mayadas,et al.  Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase. , 2005, Blood.

[33]  William A Banks,et al.  Blood-brain barrier transport of cytokines: a mechanism for neuropathology. , 2005, Current pharmaceutical design.

[34]  J. Bart,et al.  Blood–brain barrier dysfunction in parkinsonian midbrain in vivo , 2005, Annals of neurology.

[35]  W. Hall,et al.  New frontiers in translational research in neuro-oncology and the blood-brain barrier: report of the tenth annual Blood-Brain Barrier Disruption Consortium Meeting. , 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

[36]  J. V. van Buul,et al.  Trading spaces: Rap, Rac, and Rho as architects of transendothelial migration , 2005, Current opinion in hematology.

[37]  J. Huber,et al.  Hypoxia‐inducible factor and nuclear factor kappa‐B activation in blood–brain barrier endothelium under hypoxic/reoxygenation stress , 2005, Journal of neurochemistry.

[38]  M. Macías-Silva,et al.  Assembly and sealing of tight junctions: Possible participation of G-proteins, phospholipase C, protein kinase C and calmodulin , 1991, The Journal of Membrane Biology.

[39]  M. Geng,et al.  Glucose transporter 1, distribution in the brain and in neural disorders: its relationship with transport of neuroactive drugs through the blood-brain barrier. , 2005, Biochemical genetics.

[40]  E. Ben-Menachem,et al.  Increased vulnerability of the blood-brain barrier to acute hypertension following depletion of brain noradrenaline , 2005, Journal of Neural Transmission.

[41]  M. Cereijido,et al.  Tight junction formation in cultured epithelial cells (MDCK) , 2005, The Journal of Membrane Biology.

[42]  N. Abbott.  Dynamics of CNS Barriers: Evolution, Differentiation, and Modulation , 2005, Cellular and Molecular Neurobiology.

[43]  F. Schmitt,et al.  Neuroimaging correlates of HIV-associated BBB compromise , 2004, Journal of Neuroimmunology.

[44]  R. Banati,et al.  Brain microglia and blood-derived macrophages: molecular profiles and functional roles in multiple sclerosis and animal models of autoimmune demyelinating disease , 2004, Brain Research Reviews.

[45]  T. Matsui,et al.  Establishment and Characterization of Cultured Epithelial Cells Lacking Expression of ZO-1* , 2004, Journal of Biological Chemistry.

[46]  T. Yamashita,et al.  Thr(207) of claudin-5 is involved in size-selective loosening of the endothelial barrier by cyclic AMP. , 2004, Experimental cell research.

[47]  D. Ray,et al.  Reversible disruption of tight junction complexes in the rat blood‐brain barrier, following transitory focal astrocyte loss , 2004, Glia.

[48]  E. Masliah,et al.  Altered P‐Glycoprotein Expression in AIDS Patients with HIV Encephalitis , 2004, Journal of neuropathology and experimental neurology.

[49]  Y. Shen,et al.  The CLDN5 locus may be involved in the vulnerability to schizophrenia , 2004, European Psychiatry.

[50]  Hans Lassmann,et al.  Recent neuropathological findings in MS—implications for diagnosis and therapy , 2004, Journal of Neurology.

[51]  R. Bendayan,et al.  Functional Expression and Localization of P-glycoprotein in the Central Nervous System: Relevance to the Pathogenesis and Treatment of Neurological Disorders , 2004, Pharmaceutical Research.

[52]  P. Hordijk,et al.  Signaling in Leukocyte Transendothelial Migration , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[53]  S. Cisternino,et al.  Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier. , 2004, Cancer research.

[54]  W. Muller,et al.  Locomotion of monocytes on endothelium is a critical step during extravasation , 2004, Nature Immunology.

[55]  G. Fricker,et al.  Modulation of Drug Transporters at the Blood-Brain Barrier , 2004, Pharmacology.

[56]  D. Ray,et al.  Focal astrocyte loss is followed by microvascular damage, with subsequent repair of the blood‐brain barrier in the apparent absence of direct astrocytic contact , 2004, Glia.

[57]  C. Kunsch,et al.  Selective Inhibition of Endothelial and Monocyte Redox-Sensitive Genes by AGI-1067: A Novel Antioxidant and Anti-Inflammatory Agent , 2004, Journal of Pharmacology and Experimental Therapeutics.

[58]  C. L. Graff,et al.  Drug transport at the blood-brain barrier and the choroid plexus. , 2004, Current drug metabolism.

[59]  Krister Wennerberg,et al.  Rho and Rac Take Center Stage , 2004, Cell.

[60]  N. Suttorp,et al.  Rho Protein Inhibition Blocks Cyclooxygenase-2 Expression by Proinflammatory Mediators in Endothelial Cells , 2003, Inflammation.

[61]  N. Abbott.  Inflammatory Mediators and Modulation of Blood–Brain Barrier Permeability , 2000, Cellular and Molecular Neurobiology.

[62]  J. Alexander,et al.  The Role of Cadherin Endocytosis in Endothelial Barrier Regulation: Involvement of Protein Kinase C and Actin-Cadherin Interactions , 1998, Inflammation.

[63]  E. López-Bayghen,et al.  The tight junction protein ZO-2 associates with Jun, Fos and C/EBP transcription factors in epithelial cells. , 2004, Experimental cell research.

[64]  W. Pardridge.  Molecular biology of the blood-brain barrier , 2005, Methods in molecular medicine.

[65]  C. Jun,et al.  Endothelial Cells Proactively Form Microvilli-Like Membrane Projections upon Intercellular Adhesion Molecule 1 Engagement of Leukocyte LFA-1 1 , 2003, The Journal of Immunology.

[66]  Alireza Minagar,et al.  Blood-brain barrier disruption in multiple sclerosis , 2003, Multiple sclerosis.

[67]  R. Keep,et al.  Potential role of MCP-1 in endothelial cell tight junction `opening': signaling via Rho and Rho kinase , 2003, Journal of Cell Science.

[68]  M. Itoh,et al.  Expression and distribution of ZO‐3, a tight junction MAGUK protein, in mouse tissues , 2003, Genes to cells : devoted to molecular & cellular mechanisms.

[69]  H. Gendelman,et al.  Mononuclear phagocyte immunity and the neuropathogenesis of HIV‐1 infection , 2003, Journal of leukocyte biology.

[70]  Hong Zhang,et al.  The FASEB Journal express article 10.1096/fj.02-1131fje. Published online September 4, 2003. Expression and functional characterization of ABCG2 in brain endothelial cells and vessels , 2022 .

[71]  John G. Collard,et al.  Calcium Signaling Regulates Translocation and Activation of Rac* , 2003, Journal of Biological Chemistry.

[72]  K. Beyenbach.  Regulation of tight junction permeability with switch-like speed , 2003, Current opinion in nephrology and hypertension.

[73]  W. Muller.  Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. , 2003, Trends in immunology.

[74]  A. Vorbrodt,et al.  Molecular anatomy of intercellular junctions in brain endothelial and epithelial barriers: electron microscopist’s view , 2003, Brain Research Reviews.

[75]  S. Tsukita,et al.  Expression of claudin‐5 in dermal vascular endothelia , 2003, Experimental dermatology.

[76]  S. Tsukita,et al.  Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice , 2003, The Journal of cell biology.

[77]  D. Janigro,et al.  Vascular and parenchymal mechanisms in multiple drug resistance: a lesson from human epilepsy. , 2003, Current drug targets.

[78]  A. Traweger,et al.  The Tight Junction Protein ZO-2 Localizes to the Nucleus and Interacts with the Heterogeneous Nuclear Ribonucleoprotein Scaffold Attachment Factor-B* , 2003, The Journal of Biological Chemistry.

[79]  A. Schinkel,et al.  Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview. , 2003, Advanced drug delivery reviews.

[80]  W. Wells.  Redox regulation , 2002, The Journal of Cell Biology.

[81]  B. Zlokovic.  Vascular disorder in Alzheimer's disease: role in pathogenesis of dementia and therapeutic targets. , 2002, Advanced drug delivery reviews.

[82]  J. Cook-Mills.  VCAM-1 signals during lymphocyte migration: role of reactive oxygen species. , 2002, Molecular immunology.

[83]  K. Paemeleire.  The cellular basis of neurovascular metabolic coupling. , 2002, Acta neurologica Belgica.

[84]  E. Levin,et al.  Deciphering Vascular Endothelial Cell Growth Factor/Vascular Permeability Factor Signaling to Vascular Permeability , 2002, The Journal of Biological Chemistry.

[85]  M. Aurrand-Lions,et al.  Role of interendothelial adhesion molecules in the control of vascular functions. , 2002, Vascular pharmacology.

[86]  C. White,et al.  Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex , 2002, The Journal of cell biology.

[87]  C. Engelbertz,et al.  Expression and adhesive properties of basement membrane proteins in cerebral capillary endothelial cell cultures , 2002, Cell and Tissue Research.

[88]  A. Kubar,et al.  Early pericyte response to brain hypoxia in cats: an ultrastructural study. , 2002, Microvascular research.

[89]  María Yáñez-Mó,et al.  Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes , 2002, The Journal of cell biology.

[90]  T. Davis,et al.  Calcium Modulation of Adherens and Tight Junction Function: A Potential Mechanism for Blood-Brain Barrier Disruption After Stroke , 2002, Stroke.

[91]  Hartwig Wolburg,et al.  Tight junctions of the blood-brain barrier: development, composition and regulation. , 2002, Vascular pharmacology.

[92]  John G. Collard,et al.  Reactive oxygen species mediate Rac-induced loss of cell-cell adhesion in primary human endothelial cells. , 2002, Journal of cell science.

[93]  N. Abbott.  Astrocyte–endothelial interactions and blood–brain barrier permeability , 2002, Journal of anatomy.

[94]  H. Barth,et al.  Endothelial Rho signaling is required for monocyte transendothelial migration , 2002, FEBS letters.

[95]  T. Davis,et al.  Cerebral microvascular changes in permeability and tight junctions induced by hypoxia-reoxygenation. , 2002, American journal of physiology. Heart and circulatory physiology.

[96]  Arne Fischmann,et al.  Extracellular matrix and the blood-brain barrier in glioblastoma multiforme: spatial segregation of tenascin and agrin , 2002, Acta Neuropathologica.

[97]  Tetsuo Noda,et al.  Claudin-based tight junctions are crucial for the mammalian epidermal barrier , 2002, The Journal of cell biology.

[98]  L. González-Mariscal,et al.  Nuclear localization of the tight junction protein ZO-2 in epithelial cells. , 2002, Experimental cell research.

[99]  C. Pothoulakis,et al.  Protein Kinase C Signaling Regulates ZO-1 Translocation and Increased Paracellular Flux of T84 Colonocytes Exposed toClostridium difficile Toxin A* , 2002, The Journal of Biological Chemistry.

[100]  E. Wolpert,et al.  Hydrocortisone decreases retinal endothelial cell water and solute flux coincident with increased content and decreased phosphorylation of occludin , 2002, Journal of neurochemistry.

[101]  W. Banks,et al.  Strategies for the Delivery of Leptin to the CNS , 2002, Journal of drug targeting.

[102]  R. Egleton,et al.  Molecular physiology and pathophysiology of tight junctions in the blood–brain barrier , 2001, Trends in Neurosciences.

[103]  R. Bendayan,et al.  Drug transporters in the central nervous system: brain barriers and brain parenchyma considerations. , 2001, Pharmacological reviews.

[104]  I. Blasig,et al.  Protein Kinase C Regulates the Phosphorylation and Cellular Localization of Occludin* , 2001, The Journal of Biological Chemistry.

[105]  J. Wettstein,et al.  Elements of cerebral microvascular ischaemia , 2001, Brain Research Reviews.

[106]  A. Lackner,et al.  Perivascular Macrophages Are the Primary Cell Type Productively Infected by Simian Immunodeficiency Virus in the Brains of Macaques , 2001, The Journal of experimental medicine.

[107]  S. Tsukita,et al.  Regulation of Tight Junction Permeability and Occludin Phosphorylation by RhoA-p160ROCK-dependent and -independent Mechanisms* , 2001, The Journal of Biological Chemistry.

[108]  F. Luscinskas,et al.  Real-Time Imaging of Vascular Endothelial-Cadherin During Leukocyte Transmigration Across Endothelium , 2001 .

[109]  M. Papadopoulos,et al.  Emerging molecular mechanisms of brain tumour oedema. , 2001, British journal of neurosurgery.

[110]  B. McEwen,et al.  Neurotrophic and neuroprotective actions of estrogens and their therapeutic implications. , 2001, Annual review of pharmacology and toxicology.

[111]  A. Tarnawski,et al.  Mechanism of extracellular calcium regulation of intestinal epithelial tight junction permeability: Role of cytoskeletal involvement , 2000, Microscopy research and technique.

[112]  J. Greenwood,et al.  ICAM-1-Coupled Cytoskeletal Rearrangements and Transendothelial Lymphocyte Migration Involve Intracellular Calcium Signaling in Brain Endothelial Cell Lines1 , 2000, The Journal of Immunology.

[113]  A. P. Soler,et al.  Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets. , 2000, Journal of cell science.

[114]  S. Liebner,et al.  Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of human glioblastoma multiforme , 2000, Acta Neuropathologica.

[115]  H. Gendelman,et al.  Mononuclear phagocytes mediate blood‐brain barrier compromise and neuronal injury during HIV‐1‐associated dementia , 2000, Journal of leukocyte biology.

[116]  A. Ávila-Flores,et al.  MAGUK proteins: structure and role in the tight junction. , 2000, Seminars in cell & developmental biology.

[117]  J. Rafols,et al.  Pericyte migration from the vascular wall in response to traumatic brain injury. , 2000, Microvascular research.

[118]  A. Hopkins,et al.  Modulation of tight junction function by G protein-coupled events. , 2000, Advanced drug delivery reviews.

[119]  T. L. Deem,et al.  Lymphocyte Migration Through Monolayers of Endothelial Cell Lines Involves VCAM-1 Signaling Via Endothelial Cell NADPH Oxidase1 , 2000, The Journal of Immunology.

[120]  X. Tong,et al.  GABA neurons provide a rich input to microvessels but not nitric oxide neurons in the rat cerebral cortex: A means for direct regulation of local cerebral blood flow , 2000, The Journal of comparative neurology.

[121]  G. D. del Zoppo,et al.  Advances in the vascular pathophysiology of ischemic stroke. , 2000, Thrombosis research.

[122]  S. Bamforth,et al.  Disruption of epithelial tight junctions is prevented by cyclic nucleotide-dependent protein kinase inhibitors , 2000, Histochemistry and Cell Biology.

[123]  C. Catania,et al.  Neurons and ECM regulate occludin localization in brain endothelial cells , 2000, Neuroreport.

[124]  F. Luscinskas,et al.  Monocytes Induce Reversible Focal Changes in Vascular Endothelial Cadherin Complex during Transendothelial Migration under Flow , 2000, The Journal of cell biology.

[125]  O. Finco,et al.  Evidence of blood-brain barrier alteration and activation in HIV-1 gp120 transgenic mice. , 1999, AIDS.

[126]  C. Achim,et al.  Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis. , 1999, The American journal of pathology.

[127]  M. Y. Lee,et al.  Early alterations in cerebral hemodynamics, brain metabolism, and blood-brain barrier permeability in experimental intracerebral hemorrhage. , 1999, Journal of neurosurgery.

[128]  K. Frei,et al.  Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition. , 1999, Journal of cell science.

[129]  N. van Bruggen,et al.  VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain. , 1999, The Journal of clinical investigation.

[130]  P. Rieu,et al.  Redox regulation of β2‐integrin CD11b / CD18 activation , 1999 .

[131]  M. Weinand,et al.  Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis. , 1999, The American journal of pathology.

[132]  E. Dejana,et al.  Leukocyte Recruitment in the Cerebrospinal Fluid of Mice with Experimental Meningitis Is Inhibited by an Antibody to Junctional Adhesion Molecule (Jam) , 1999, The Journal of experimental medicine.

[133]  S. Tsukita,et al.  Endothelial Claudin , 1999, The Journal of cell biology.

[134]  S. Nigam,et al.  A role for intracellular calcium in tight junction reassembly after ATP depletion-repletion. , 1999, AJP - Renal Physiology.

[135]  S. Tsukita,et al.  Ca2+-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions , 1999, Current Biology.

[136]  X. Tong,et al.  Regional cholinergic denervation of cortical microvessels and nitric oxide synthase-containing neurons in Alzheimer's disease , 1999, Neuroscience.

[137]  M. Westphal,et al.  Scatter factor/hepatocyte growth factor (SF/HGF) content and function in human gliomas , 1999, International Journal of Developmental Neuroscience.

[138]  B. Stevenson.  Understanding tight junction clinical physiology at the molecular level. , 1999, The Journal of clinical investigation.

[139]  A. Ridley,et al.  Monocyte Adhesion and Spreading on Human Endothelial Cells Is Dependent on Rho-regulated Receptor Clustering , 1999, The Journal of cell biology.

[140]  K. Kaibuchi,et al.  In vivo interaction of AF-6 with activated Ras and ZO-1. , 1999, Biochemical and biophysical research communications.

[141]  S. Nigam,et al.  Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins. , 1999, American journal of physiology. Renal physiology.

[142]  P. Adamson,et al.  Lymphocyte migration through brain endothelial cell monolayers involves signaling through endothelial ICAM-1 via a rho-dependent pathway. , 1999, Journal of immunology.

[143]  M. Itoh,et al.  Characterization of ZO-2 as a MAGUK Family Member Associated with Tight as well as Adherens Junctions with a Binding Affinity to Occludin and α Catenin* , 1999, The Journal of Biological Chemistry.

[144]  J. Clements,et al.  Alterations in blood-brain barrier glucose transport in SIV-infected macaques. , 1999, Journal of neurovirology.

[145]  A. Strosberg,et al.  ICAM-1 signaling pathways associated with Rho activation in microvascular brain endothelial cells. , 1998, Journal of immunology.

[146]  James M. Anderson,et al.  The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin Cytoskeleton* , 1998, The Journal of Biological Chemistry.

[147]  E. Dejana,et al.  Junctional Adhesion Molecule, a Novel Member of the Immunoglobulin Superfamily That Distributes at Intercellular Junctions and Modulates Monocyte Transmigration , 1998, The Journal of cell biology.

[148]  V. Perry,et al.  Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood–brain barrier breakdown in vivo , 1998, Neuroscience.

[149]  Appel Ta.  AJP centennial. One hundred years of journal publication. , 1998 .

[150]  James M. Anderson,et al.  Molecular architecture of tight junctions. , 1998, Annual review of physiology.

[151]  S. Nigam,et al.  Molecular structure and assembly of the tight junction. , 1998, American journal of physiology. Renal physiology.

[152]  V. Wong.  Phosphorylation of occludin correlates with occludin localization and function at the tight junction. , 1997, American journal of physiology. Cell physiology.

[153]  E. Hamel,et al.  Journal of Cerebral Blood Flow and Metabolism Astroglial and Vascular Interactions of Noradrenaline Terminals in the Rat Cerebral Cortex , 2022 .

[154]  L. Rubin,et al.  Occludin as a possible determinant of tight junction permeability in endothelial cells. , 1997, Journal of cell science.

[155]  M. Saitou,et al.  Possible Involvement of Phosphorylation of Occludin in Tight Junction Formation , 1997, The Journal of cell biology.

[156]  Richard E Carson,et al.  Opiate receptor avidity and cerebral blood flow in Alzheimer's disease , 1997, Journal of the Neurological Sciences.

[157]  M. Weinand,et al.  A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis. , 1997, Journal of immunology.

[158]  L. Rubin,et al.  Lysophosphatidic Acid Increases Tight Junction Permeability in Cultured Brain Endothelial Cells , 1997, Journal of neurochemistry.

[159]  B. Gumbiner,et al.  A Synthetic Peptide Corresponding to the Extracellular Domain of Occludin Perturbs the Tight Junction Permeability Barrier , 1997, The Journal of cell biology.

[160]  M. Corada,et al.  Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions , 1996, The Journal of cell biology.

[161]  R. D. Lynch,et al.  Occludin is a functional component of the tight junction. , 1996, Journal of cell science.

[162]  H. Gendelman,et al.  Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain. , 1996, Journal of immunology.

[163]  J. H. Beijnen,et al.  Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs , 1994, Cell.

[164]  H. Said,et al.  Mechanism of riboflavine uptake by Caco-2 human intestinal epithelial cells. , 1994, The American journal of physiology.

[165]  M. Itoh,et al.  Occludin: a novel integral membrane protein localizing at tight junctions , 1993, The Journal of cell biology.

[166]  James M. Anderson,et al.  Assembly of the tight junction: the role of diacylglycerol , 1993, The Journal of cell biology.

[167]  P. Stewart,et al.  Re‐evaluating the role of astrocytes in blood‐brain barrier induction , 1993, Developmental Dynamics.

[168]  M. Hughes,et al.  Detection of the tight junction-associated protein ZO-1 in astrocytes and other nonepithelial cell types. , 1992, The American journal of physiology.

[169]  C. Patlak,et al.  Quantitative measurements of capillary transport in human brain tumors by computed tomography , 1991, Annals of neurology.

[170]  H. Bauer,et al.  Glial cells and neurons induce blood-brain barrier related enzymes in cultured cerebral endothelial cells , 1991, Brain Research.

[171]  M. Brightman,et al.  Development of membrane interactions between brain endothelial cells and astrocytes in vitro , 1988, International Journal of Developmental Neuroscience.

[172]  Z. Nagy,et al.  Tight junctions of brain endothelium in vitro are enhanced by astroglia , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[173]  D. Shasby,et al.  Effects of calcium on transendothelial albumin transfer and electrical resistance. , 1986, Journal of applied physiology.

[174]  C. Palant,et al.  Ca2+ regulation of tight-junction permeability and structure in Necturus gallbladder. , 1983, The American journal of physiology.

[175]  W. Oldendorf,et al.  The large apparent work capability of the blood‐brain barrier: A study of the mitochondrial content of capillary endothelial cells in brain and other tissues of the rat , 1977, Annals of neurology.