Cathepsin K regulates localization and secretion of Tartrate-Resistant Acid Phosphatase (TRAP) in TRAP-overexpressing MDA-MB-231 breast cancer cells
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[1] T. Lundbäck,et al. Identification of inhibitors of Tartrate‐resistant acid phosphatase (TRAP/ACP5) activity by small‐molecule screening , 2018, Chemical biology & drug design.
[2] Yu-Jin Dong,et al. Prognostic significance of ACP5 expression in patients with lung adenocarcinoma , 2018, The clinical respiratory journal.
[3] R. Branca,et al. Tartrate-resistant acid phosphatase (TRAP/ACP5) promotes metastasis-related properties via TGFβ2/TβR and CD44 in MDA-MB-231 breast cancer cells , 2017, BMC Cancer.
[4] D. Brömme,et al. Cathepsin K osteoporosis trials, pycnodysostosis and mouse deficiency models: Commonalities and differences , 2016, Expert opinion on drug discovery.
[5] M. Frank,et al. The small chemical enzyme inhibitor 5-phenylnicotinic acid/CD13 inhibits cell migration and invasion of tartrate-resistant acid phosphatase/ACP5-overexpressing MDA-MB-231 breast cancer cells. , 2015, Experimental cell research.
[6] P. Lång,et al. The growth factor-like adipokine tartrate-resistant acid phosphatase 5a interacts with the rod G3 domain of adipocyte-produced nidogen-2. , 2014, Biochemical and biophysical research communications.
[7] L. Duong,et al. Inhibition of bone resorption by the cathepsin K inhibitor odanacatib is fully reversible. , 2014, Bone.
[8] L. Duong,et al. Efficacy of a Cathepsin K Inhibitor in a Preclinical Model for Prevention and Treatment of Breast Cancer Bone Metastasis , 2014, Molecular Cancer Therapeutics.
[9] Y. Toiyama,et al. Clinical significance of tartrate-resistant acid phosphatase type-5 expression in human gastric cancer. , 2014, Anticancer research.
[10] Y. Nie,et al. ACP5, a direct transcriptional target of FoxM1, promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma , 2014, Oncogene.
[11] R. Baron,et al. Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation. , 2013, The Journal of clinical investigation.
[12] A. Sahu,et al. Dissection of Functional Sites in Herpesvirus Saimiri Complement Control Protein Homolog , 2012, Journal of Virology.
[13] L. Duong,et al. The effects of the cathepsin K inhibitor odanacatib on osteoclastic bone resorption and vesicular trafficking. , 2011, Bone.
[14] M. Platt,et al. Multiplex Zymography Captures Stage-specific Activity Profiles of Cathepsins K, L, and S in Human Breast, Lung, and Cervical Cancer , 2011, Journal of Translational Medicine.
[15] Gerald C. Chu,et al. Proinvasion metastasis drivers in early-stage melanoma are oncogenes. , 2011, Cancer cell.
[16] A. Jensen,et al. The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: results of a 4-week, double-blind, randomized, controlled trial. , 2010, Clinical breast cancer.
[17] G. Andersson,et al. Biogenesis of tartrate-resistant acid phosphatase isoforms 5a and 5b in stably transfected MDA-MB-231 breast cancer epithelial cells. , 2010, Biochimica et biophysica acta.
[18] Jun Yao,et al. Epithelial and Stromal Cathepsin K and CXCL14 Expression in Breast Tumor Progression , 2008, Clinical Cancer Research.
[19] R. Kiviranta,et al. Proteolytic processing and polarized secretion of tartrate-resistant acid phosphatase is altered in a subpopulation of metaphyseal osteoclasts in cathepsin K-deficient mice. , 2007, Bone.
[20] M. Warburton,et al. Human breast cancer cell lines and tissues express tartrate‐resistant acid phosphatase (TRAP) , 2007, Cell biology international.
[21] M. Krockenberger,et al. Increased tartrate-resistant acid phosphatase (TRAP) expression in malignant breast, ovarian and melanoma tissue: an investigational study , 2006, BMC Cancer.
[22] W. Seeger,et al. Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration , 2005, Respiratory research.
[23] K. Hultenby,et al. Proteolytic Excision of a Repressive Loop Domain in Tartrate-resistant Acid Phosphatase by Cathepsin K in Osteoclasts* , 2005, Journal of Biological Chemistry.
[24] N. Sträter,et al. Crystal structures of recombinant human purple Acid phosphatase with and without an inhibitory conformation of the repression loop. , 2005, Journal of molecular biology.
[25] E. G. Funhoff,et al. Substrate positioning by His92 is important in catalysis by purple acid phosphatase , 2005, The FEBS journal.
[26] N. Katunuma,et al. Involvement of cathepsins in the invasion, metastasis and proliferation of cancer cells. , 2005, The journal of medical investigation : JMI.
[27] Jyh‐cherng Yu,et al. Tartrate-resistant acid phosphatase 5b is a useful serum marker for extensive bone metastasis in breast cancer patients. , 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.
[28] T. Chao,et al. Tartrate-resistant acid phosphatase 5b as a serum marker of bone metastasis in breast cancer patients. , 2004 .
[29] V. E. Goldberg,et al. Tartrate-Resistant Acid Phosphatase as a Marker of Bone Metastases in Patients with Breast Cancer and Prostate Cancer , 2004, Bulletin of Experimental Biology and Medicine.
[30] D. Hume,et al. Phosphotyrosyl peptides and analogues as substrates and inhibitors of purple acid phosphatases. , 2004, Archives of biochemistry and biophysics.
[31] K. Hollberg,et al. TRACP as an Osteopontin Phosphatase , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[32] J. Goldman,et al. Tartrate‐resistant acid phosphatase isoform 5b: A novel serum marker for monitoring bone disease in multiple myeloma , 2003, International journal of cancer.
[33] H. Caffier,et al. Evaluation of tartrate-resistant acid phosphatase (TRAP) 5b as serum marker of bone metastases in human breast cancer. , 2003, Anticancer research.
[34] R. Thomas,et al. Cathepsin K mRNA and Protein Expression in Prostate Cancer Progression , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[35] K. Hultenby,et al. Osteoclasts from mice deficient in tartrate-resistant acid phosphatase have altered ruffled borders and disturbed intracellular vesicular transport. , 2002, Experimental cell research.
[36] Sheila J. Jones,et al. Overlapping functions of lysosomal acid phosphatase (LAP) and tartrate-resistant acid phosphatase (Acp5) revealed by doubly deficient mice. , 2001, Development.
[37] E. G. Funhoff,et al. Mutational analysis of the interaction between active site residues and the loop region in mammalian purple acid phosphatases. , 2001, Biochemistry.
[38] M. Y. Lee,et al. Heparin column analysis of serum type 5 tartrate-resistant acid phosphatase isoforms. , 2001, Journal of chromatography. B, Biomedical sciences and applications.
[39] Jozef Van Beeumen,et al. The Highly Exposed Loop Region in Mammalian Purple Acid Phosphatase Controls the Catalytic Activity , 2001, Chembiochem : a European journal of chemical biology.
[40] I. James,et al. Biosynthesis and processing of cathepsin K in cultured human osteoclasts. , 2001, Bone.
[41] D. Hume,et al. Structure, function, and regulation of tartrate-resistant acid phosphatase. , 2000, Bone.
[42] G. Andersson,et al. Tartrate-resistant purple acid phosphatase is synthesized as a latent proenzyme and activated by cysteine proteinases. , 1999, The Biochemical journal.
[43] Sheila J. Jones,et al. Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[44] K. Kanaoka,et al. Fluorescence microscopic demonstration of cathepsin K activity as the major lysosomal cysteine proteinase in osteoclasts. , 1998, Journal of biochemistry.
[45] J. Sloane,et al. The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma. , 1997, Cancer research.
[46] G. Andersson,et al. Comparative studies of rat recombinant purple acid phosphatase and bone tartrate-resistant acid phosphatase. , 1997, The Biochemical journal.
[47] C. Debouck,et al. Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts (*) , 1996, The Journal of Biological Chemistry.
[48] D. Mcnulty,et al. Proteolytic Activity of Human Osteoclast Cathepsin K , 1996, The Journal of Biological Chemistry.
[49] G. Andersson,et al. The tartrate-resistant purple acid phosphatase of bone osteoclasts--a protein phosphatase with multivalent substrate specificity and regulation. , 1995, Acta orthopaedica Scandinavica. Supplementum.
[50] R. Glew,et al. Substrate specificity of Gaucher spleen phosphoprotein phosphatase. , 1981, Archives of biochemistry and biophysics.
[51] F. Guo,et al. Overexpressed ACP5 has prognostic value in colorectal cancer and promotes cell proliferation and tumorigenesis via FAK/PI3K/AKT signaling pathway. , 2019, American journal of cancer research.
[52] N. Kushlinskii,et al. Tartrate-resistant acid phosphatase as a marker of bone metastases in patients with breast cancer and prostate cancer , 2007, Bulletin of Experimental Biology and Medicine.
[53] G. Andersson. Research Article Differential expression of monomeric and proteolytically processed forms of tartrate-resistant acid phosphatase in rat tissues , 2005 .
[54] Hilde van der Togt,et al. Publisher's Note , 2003, J. Netw. Comput. Appl..
[55] M. Halushka,et al. Concise Report , 2022 .