Walking Two Worlds—Adolescent and Young Adult Oncology. Proceedings of a Symposium held by the Pediatric Oncology Group of Ontario

Psychosocial research examining the impact of cancer on adolescents and young adults has focused mostly on domains relating to family, psychological/emotional impact and social effects. An overview of the evidence-based literature available in each of these domains is presented to highlight the trends and provide a basis for clinical application. A review of the research literature was conducted to summarize what is known regarding the psychosocial dimensions of cancer in adolescents and young adults. Key elements critical to the psychosocial adaptation of the adolescents and young adults with cancer, as well as later effects of the cancer experience, are discussed in terms of clinical implications. A case example is utilized to demonstrate the application of what has been investigated empirically in regard to psychosocial dimensions of cancer in young adults and adolescents. Studies have identified various psychosocial challenges that adolescents and young adults experience when faced with cancer. Further research, incorporating the effects of treatment stage and developmental level of the patient on specific psychosocial dimensions of the cancer experience, is needed. Evidence-based information regarding the influence and interaction of family, psychological and emotional state, and social status of adolescents and young adults with cancer can aid clinicians when developing psychosocial assessment and treatment approaches for these patients. Cancer 2006;107(7 Suppl):1663–71. � 2006 American Cancer Society.

[1]  A. Frank Suffering: A Sociological Introduction (review) , 2007 .

[2]  M. Barrera,et al.  Educational and social late effects of childhood cancer and related clinical, personal, and familial characteristics , 2005, Cancer.

[3]  K. Oktay Fertility preservation: an emerging discipline in the care of young patients with cancer. , 2005, The Lancet. Oncology.

[4]  Mark L. Greenberg,et al.  Use of paediatric versus adult oncology treatment centres by adolescents 15-19 years old: the Canadian Childhood Cancer Surveillance and Control Program. , 2005, European journal of cancer.

[5]  R. Woodgate,et al.  A Different Way of Being: Adolescents' Experiences With Cancer , 2005, Cancer nursing.

[6]  H. Koot,et al.  Quality of life in children surviving cancer: a personality and multi-informant perspective. , 2004, Journal of pediatric psychology.

[7]  Mark L. Greenberg,et al.  Function and quality-of-life of survivors of pelvic and lower extremity osteosarcoma and Ewing's sarcoma: the Childhood Cancer Survivor Study , 2004, British Journal of Cancer.

[8]  L. Zeltzer,et al.  Fertility issues for young adult survivors of childhood cancer , 2004, Psycho-oncology.

[9]  F. Biley,et al.  Thoughts on the therapeutic use of narrative in the promotion of coping in cancer care. , 2004, European journal of cancer care.

[10]  Outi Ahonen,et al.  Adolescents With Cancer: Experience of Life and How It Could Be Made Easier , 2004, Cancer nursing.

[11]  G. Bodegård,et al.  Life After Cancer in Childhood: Social Adjustment and Educational and Vocational Status of Young-Adult Survivors , 2004, Journal of pediatric hematology/oncology.

[12]  Denise M. Dudzinski Ethical issues in fertility preservation for adolescent cancer survivors: oocyte and ovarian tissue cryopreservation. , 2004, Journal of pediatric and adolescent gynecology.

[13]  A. Kazak,et al.  Posttraumatic stress disorder (PTSD) and posttraumatic stress symptoms (PTSS) in families of adolescent childhood cancer survivors. , 2004, Journal of pediatric psychology.

[14]  L. Robison,et al.  Psychological outcomes in long-term survivors of childhood brain cancer: a report from the childhood cancer survivor study. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[15]  A. Frank After Methods, the Story: From Incongruity to Truth in Qualitative Research , 2004, Qualitative health research.

[16]  Z. Blumenfeld Gynaecologic concerns for young women exposed to gonadotoxic chemotherapy , 2003, Current opinion in obstetrics & gynecology.

[17]  Jami F. Young,et al.  Predicting intraindividual self-concept trajectories during adolescence. , 2003, Journal of adolescence.

[18]  A. McTiernan Issues surrounding the participation of adolescents with cancer in clinical trials in the UK. , 2003, European journal of cancer care.

[19]  R. Weksberg,et al.  Developmental Differences in Psychological Adjustment and Health-Related Quality of Life in Pediatric Cancer Patients , 2003 .

[20]  Catherine S. Ashcraft Adolescent Ambiguities in American Pie , 2003 .

[21]  R. McNally,et al.  Adult psychosocial functioning following childhood cancer: the different roles of sons' and daughters' relationships with their fathers and mothers , 2003 .

[22]  P. Rosoff,et al.  Preserving Fertility In Young Cancer Patients: A Medical, Ethical And Legal Challenge , 2003 .

[23]  Leslie Bernstein,et al.  Childhood cancer patients' access to cooperative group cancer programs , 2003, Cancer.

[24]  L. Robison,et al.  Utilization of special education services and educational attainment among long‐term survivors of childhood cancer , 2003, Cancer.

[25]  E. Blyth Subsidized IVF: the development of ‘egg sharing’ in the UK , 2002 .

[26]  M. Coleman,et al.  Childhood cancer survival in Europe and the United States , 2002, Cancer.

[27]  S. Manne,et al.  Coping in Children With Cancer: Examining the Goodness-of-Fit Hypothesis , 2002 .

[28]  L. Robison,et al.  Psychological outcomes in long-term survivors of childhood leukemia, Hodgkin's disease, and non-Hodgkin's lymphoma: a report from the Childhood Cancer Survivor Study. , 2002, Pediatrics.

[29]  M. Vacher-Lavenu,et al.  Human ovarian tissue cryopreservation: indications and feasibility. , 2002, Human reproduction.

[30]  D. Bearison,et al.  Cancer Narratives of Adolescents and Young Adults: A Quantitative and Qualitative Analysis , 2002 .

[31]  K. Oktay Evidence for limiting ovarian tissue harvesting for the purpose of transplantation to women younger than 40 years of age. , 2002, The Journal of clinical endocrinology and metabolism.

[32]  K. Oktay,et al.  The potential of ovarian tissue transplant to preserve fertility , 2002, Expert opinion on biological therapy.

[33]  M. Chesler,et al.  Quality of life in childhood cancer survivors , 2002, Psycho-oncology.

[34]  A. Kazak,et al.  Family systems practice in pediatric psychology. , 2002, Journal of pediatric psychology.

[35]  Wininger Jd,et al.  Cryopreservation of Immature and Mature Human Oocytes , 2002, Seminars in reproductive medicine.

[36]  K. Oktay Ovarian tissue cryopreservation and transplantation: preliminary findings and implications for cancer patients. , 2001, Human reproduction update.

[37]  J. Balasch,et al.  Long-term ovarian function evaluation after autografting by implantation with fresh and frozen-thawed human ovarian tissue. , 2001, The Journal of clinical endocrinology and metabolism.

[38]  R. Boyle,et al.  Gamete retrieval in terminal conditions. , 2001, American journal of obstetrics and gynecology.

[39]  J. Rodrigue,et al.  Brief report: perceptions of young adolescents about a hypothetical new peer with cancer: an analog study. , 2001, Journal of pediatric psychology.

[40]  M. Soules,et al.  The future of human ovarian cryopreservation and transplantation: fertility and beyond. , 2001, Fertility and sterility.

[41]  Z. Rosenwaks,et al.  Recent progress in oocyte and ovarian tissue cryopreservation and transplantation , 2001, Current opinion in obstetrics & gynecology.

[42]  W. Wallace,et al.  Fertility preservation for children treated for cancer (1): scientific advances and research dilemmas , 2001, Archives of disease in childhood.

[43]  H. Kyngäs,et al.  Coping with the onset of cancer: coping strategies and resources of young people with cancer. , 2001, European journal of cancer care.

[44]  A. Ishibashi The Needs of Children and Adolescents With Cancer for Information and Social Support , 2001, Cancer nursing.

[45]  M. A. Ritchie PSYCHOSOCIAL NURSING CARE FOR ADOLESCENTS WITH CANCER , 2001, Issues in comprehensive pediatric nursing.

[46]  S. Golombok,et al.  Oocyte and semen donation: a survey of UK licensed centres. , 2000, Human reproduction.

[47]  S. Fishel,et al.  Fertility preservation of boys undergoing anti-cancer therapy: a review of the existing situation and prospects for the future. , 2000, Human reproduction.

[48]  K. Oktay,et al.  Ovarian function after transplantation of frozen, banked autologous ovarian tissue. , 2000, The New England journal of medicine.

[49]  A. Frank,et al.  The Standpoint of Storyteller , 2000, Qualitative health research.

[50]  R. Slaughter,et al.  Review of research studies that evaluated the impact of treatment for childhood cancers on neurocognition and behavioral and social competence: nursing implications. , 2000, Journal of the Society of Pediatric Nurses : JSPN.

[51]  R. Lambert,et al.  Identity in adolescent survivors of childhood cancer. , 2000, Journal of pediatric psychology.

[52]  Ronald T. Brown,et al.  Social skills and psychological adjustment of child and adolescent cancer survivors , 2000, Psycho-oncology.

[53]  J. Byrne,et al.  Infertility and premature menopause in childhood cancer survivors. , 1999, Medical and pediatric oncology.

[54]  C. Schwartz,et al.  An evaluation of a psychosocial intervention for survivors of childhood cancer: paradoxical effects of response shift over time , 1999, Psycho-oncology.

[55]  C. Newton,et al.  The Fertility Problem Inventory: measuring perceived infertility-related stress. , 1999, Fertility and sterility.

[56]  Raymond K. Mulhern,et al.  Maternal Problem-Solving Therapy in Pediatric Cancer , 1999 .

[57]  T. Révész,et al.  Self-Perception Profile in Children with Cancer: Self vs Parent Report , 1999, Psychological reports.

[58]  Jeffrey L. Dcrevensky,et al.  Children with Cancer , 1998 .

[59]  A. Formann,et al.  Quality of life and psychosocial adjustment of young patients after treatment of bone cancer , 1998, Cancer.

[60]  H. Newton The cryopreservation of ovarian tissue as a strategy for preserving the fertility of cancer patients. , 1998, Human reproduction update.

[61]  S. Manne,et al.  Social support, social conflict, and adjustment among adolescents with cancer. , 1998, Journal of pediatric psychology.

[62]  Francine Mandel,et al.  Posttraumatic Stress Disorder and Family Functioning in Adolescent Cancer , 1998, Journal of traumatic stress.

[63]  A. Bleyer,et al.  National cancer clinical trials: children have equal access; adolescents do not. , 1997, The Journal of adolescent health : official publication of the Society for Adolescent Medicine.

[64]  A. Greil,et al.  Infertility and psychological distress: a critical review of the literature. , 1997, Social science & medicine.

[65]  J. Schulman,et al.  Preservation of reproductive function before therapy for cancer: new options involving sperm and ovary cryopreservation. , 1997, The cancer journal from Scientific American.

[66]  G. Cuddeback,et al.  A support group intervention to facilitate young adults' adjustment to cancer. , 1997, Health & social work.

[67]  A. Trounson,et al.  Oncological implications in the replacement of ovarian tissue. , 1997, Human reproduction.

[68]  L. Dahlquist,et al.  Body image and psychosocial adjustment in adolescent cancer survivors. , 1997, Journal of pediatric psychology.

[69]  G. Ohel,et al.  Late manifestation of pelvic abscess following oocyte retrieval, for in vitro fertilization, in patients with severe endometriosis and ovarian endometriomata , 1997, Journal of Assisted Reproduction and Genetics.

[70]  J. Jutai,et al.  Adolescents with physical disabilities: some psychosocial aspects of health. , 1996, The Journal of adolescent health : official publication of the Society for Adolescent Medicine.

[71]  E. C. Wood,et al.  Fresh and cryopreserved ovarian tissue samples from donors with lymphoma transmit the cancer to graft recipients. , 1996, Human reproduction.

[72]  A. Goldstone,et al.  Hepatitis B transmission from contaminated cryopreservation tank , 1995, The Lancet.

[73]  T. Fears,et al.  Educational attainment in long-term survivors of childhood acute lymphoblastic leukemia. , 1994, JAMA.

[74]  J. Varni,et al.  Perceived Stress and Adjustment of Long-Term Survivors of Childhood Cancer , 1994 .

[75]  S. Sexson,et al.  Adolescent cancer survivors. Psychosocial and familial adaptation. , 1994, Psychosomatics.

[76]  J. Glazer,et al.  Quality of Life in Pediatric Psychiatry: A New Outcome Measure , 1994 .

[77]  W. Bukowski,et al.  Adjustment in the peer system of adolescents with cancer: a two-year study. , 1993, Journal of pediatric psychology.

[78]  W. Bleyer What can be learned about childhood cancer from “cancer statistics review 1973–1988” , 1993, Cancer.

[79]  J. Byrne,et al.  Fertility and pregnancy after treatment for cancer during childhood or adolescence , 1993, Cancer.

[80]  M. Zevon,et al.  Adolescents with Cancer , 1993 .

[81]  D. Cella,et al.  Lives in a balance: perceived family functioning and the psychosocial adjustment of adolescent cancer survivors. , 1992, Family process.

[82]  C. Collins,et al.  Failure to master early developmental tasks as a predictor of adaptation to cancer in the young adult. , 1992, Oncology nursing forum.

[83]  O. Barbarin,et al.  Does "telling" less protect more? Relationships among age, information disclosure, and what children with cancer see and feel. , 1991, Journal of pediatric psychology.

[84]  A. Yuzpe,et al.  Psychological assessment and follow-up after in vitro fertilization: assessing the impact of failure. , 1990, Fertility and sterility.

[85]  R. Casper,et al.  Transvaginal, ultrasound-guided oocyte retrieval for in vitro fertilization. , 1989, The Journal of reproductive medicine.

[86]  E. Katz,et al.  School and Social Reintegration of Children with Cancer , 1989 .

[87]  G. Fritz,et al.  Issues of adolescent development for survivors of childhood cancer. , 1988, Journal of the American Academy of Child and Adolescent Psychiatry.

[88]  L. Robison,et al.  Personality Characteristics and Psychosocial Adjustment of Long-Term Survivors of Childhood Cancer , 1988 .

[89]  M. Gavaghan,et al.  Ego identity development of adolescents with cancer. , 1987, Journal of pediatric psychology.

[90]  N. Hurlbut,et al.  The self-esteem of adolescents with cerebral palsy. , 1986, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[91]  R. Jamison,et al.  Cooperation with treatment in adolescent cancer patients. , 1986, Journal of adolescent health care : official publication of the Society for Adolescent Medicine.

[92]  T. Beauchamp,et al.  A History and Theory of Informed Consent , 1986, American Political Science Review.

[93]  Margaret Adams-Greenly Ms Helping Children Communicate Serious Illness and Death About , 1984 .

[94]  D. Levinson,et al.  Seasons of a man's life , 1978 .

[95]  J. Marcia Development and validation of ego-identity status. , 1966, Journal of personality and social psychology.

[96]  W. Bleyer Cancer in older adolescents and young adults: epidemiology, diagnosis, treatment, survival, and importance of clinical trials. , 2002, Medical and pediatric oncology.

[97]  P. B. Miller,et al.  Acute ureteral obstruction following transvaginal oocyte retrieval for IVF. , 2002, Human reproduction.

[98]  R. Berard,et al.  Psychological vulnerability and resilience to emotional distress: A focus group study of adolescent cancer patients , 2001 .

[99]  Sarah J. Erickson,et al.  Themes Arising in Group Therapy for Adolescents With Cancer and Their Parents , 2000 .

[100]  R. McMahon,et al.  Parental Monitoring and the Prevention of Child and Adolescent Problem Behavior: A Conceptual and Empirical Formulation , 1998, Clinical child and family psychology review.

[101]  K. Oktay,et al.  Cryopreservation of immature human oocytes and ovarian tissue: an emerging technology? , 1998, Fertility and sterility.

[102]  B. Bracken Handbook of self-concept: Developmental, social, and clinical considerations. , 1996 .

[103]  Arthur W. Frank,et al.  The Wounded Storyteller: Body, Illness, and Ethics , 1995 .

[104]  R. DiClemente,et al.  School-based interventions to prevent unprotected sex and HIV among adolescents , 1994 .

[105]  R. Friedman,et al.  The psychological impact of infertility: a comparison with patients with other medical conditions. , 1993, Journal of psychosomatic obstetrics and gynaecology.

[106]  C. Midgley,et al.  Development during adolescence. The impact of stage-environment fit on young adolescents' experiences in schools and in families. , 1993, The American psychologist.

[107]  Dale A. Blyth,et al.  Moving into adolescence: The impact of pubertal change and school context. , 1987 .

[108]  S. A. Miller,et al.  Promoting self-esteem in the hospitalized adolescent: clinical interventions. , 1987, Issues in comprehensive pediatric nursing.

[109]  B. Leventhal,et al.  Intermittent high dose corticosteroid treatment in childhood cancer: behavioral and emotional consequences. , 1986, Journal of the American Academy of Child Psychiatry.

[110]  S. Harter,et al.  Development perspectives on the self-system , 1983 .

[111]  G. Koocher,et al.  The Damocles syndrome: Psychosocial consequences of surviving childhood cancer , 1981 .