First experiences of photoacoustic imaging for detection of melanoma metastases in resected human lymph nodes

Excision and histological assessment of the first draining node (sentinel lymph node) is a frequently used method to assess metastatic lymph node involvement related to cutaneous melanoma. Due to the time required for accurate histological assessment, nodal status is not immediately available to the surgeon. Hence, in case histological examination shows metastases, the patient has to be recalled to perform additional lymphadenectomy. To overcome these drawbacks we studied the applicability of photoacoustic tomographic imaging as an intra‐operative modality for examining the status of resected lymph nodes.

[1]  Robert W Schoonover,et al.  Image reconstruction in photoacoustic tomography involving layered acoustic media. , 2011, Journal of the Optical Society of America. A, Optics, image science, and vision.

[2]  Vasilis Ntziachristos,et al.  Performance of iterative optoacoustic tomography with experimental data , 2009 .

[3]  R. Schmidt,et al.  US-guided core needle biopsy of axillary lymph nodes in patients with breast cancer: why and how to do it. , 2007, Radiographics : a review publication of the Radiological Society of North America, Inc.

[4]  Vasilis Ntziachristos,et al.  Volumetric real-time multispectral optoacoustic tomography of biomarkers , 2011, Nature Protocols.

[5]  P. G. Lang,et al.  Sentinel-Node Biopsy or Nodal Observation in Melanoma , 2007 .

[6]  Andreas Mandelis,et al.  Photothermoacoustic imaging of biological tissues: maximum depth characterization comparison of time and frequency-domain measurements. , 2009, Journal of biomedical optics.

[7]  C. Compton,et al.  The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM , 2010, Annals of Surgical Oncology.

[8]  Wiendelt Steenbergen,et al.  Passive element enriched photoacoustic computed tomography (PER PACT) for simultaneous imaging of acoustic propagation properties and light absorption. , 2011, Optics express.

[9]  R. Elashoff,et al.  Sentinel-node biopsy or nodal observation in melanoma. , 2006, The New England journal of medicine.

[10]  J. Ferlay,et al.  Estimates of cancer incidence and mortality in Europe in 2008. , 2010, European journal of cancer.

[11]  John A. Viator,et al.  Enhanced photoacoustic detection of melanoma cells using gold nanoparticles , 2011, Lasers in surgery and medicine.

[12]  M. Ross,et al.  Complications Associated With Sentinel Lymph Node Biopsy for Melanoma , 2003, Annals of Surgical Oncology.

[13]  M A Weinstock,et al.  Epidemiology of melanoma. , 2017, Cancer treatment and research.

[14]  A Breslow,et al.  Thickness, Cross‐Sectional Areas and Depth of Invasion in the Prognosis of Cutaneous Melanoma , 1970, Annals of surgery.

[15]  Junjie Yao,et al.  Photoacoustic tomography: fundamentals, advances and prospects. , 2011, Contrast media & molecular imaging.

[16]  Arjen Amelink,et al.  Characterization of Mediastinal Lymph Node Physiology In Vivo by Optical Spectroscopy during Endoscopic Ultrasound-Guided Fine Needle Aspiration , 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[17]  Thomas Kelly,et al.  In vivo magnetic enrichment and multiplex photoacoustic detection of circulating tumour cells. , 2009, Nature nanotechnology.

[18]  Wenfeng Xia,et al.  Photoacoustic Imaging of the Breast Using the Twente Photoacoustic Mammoscope: Present Status and Future Perspectives , 2010, IEEE Journal of Selected Topics in Quantum Electronics.

[19]  Mustafa Sarimollaoglu,et al.  In vivo ultra‐fast photoacoustic flow cytometry of circulating human melanoma cells using near‐infrared high‐pulse rate lasers , 2011, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[20]  M. Wallace,et al.  Endosonographic features predictive of malignancy in mediastinal lymph nodes in patients with lung cancer. , 2010, Gastrointestinal endoscopy.

[21]  Benjamin S. Goldschmidt,et al.  Photoacoustic detection of melanoma micrometastasis in sentinel lymph nodes. , 2009, Journal of biomechanical engineering.

[22]  Thomas Berer,et al.  Three-dimensional photoacoustic imaging using fiber-based line detectors. , 2010, Journal of biomedical optics.

[23]  Wiendelt Steenbergen,et al.  Initial results of imaging melanoma metastasis in resected human lymph nodes using photoacoustic computed tomography. , 2011, Journal of biomedical optics.

[24]  P. Beard Biomedical photoacoustic imaging , 2011, Interface Focus.

[25]  M. Smith,et al.  A systematic review of the staging performance of endoscopic ultrasound in gastro-oesophageal carcinoma , 2001, Gut.

[26]  J. Ferlay,et al.  Estimates of the cancer incidence and mortality in Europe in 2006. , 2006, Annals of oncology : official journal of the European Society for Medical Oncology.

[27]  D. Prough,et al.  Noninvasive monitoring of cerebral blood oxygenation in ovine superior sagittal sinus with novel multi-wavelength optoacoustic system. , 2009, Optics express.

[28]  R. Zemp,et al.  Estimating optical absorption, scattering, and Grueneisen distributions with multiple-illumination photoacoustic tomography. , 2011, Applied optics.

[29]  I. B. Rinkes,et al.  Sentinel Node Biopsies in Melanoma Patients: A Protocol for Accurate, Efficient, and Cost-Effective Analysis by Preselection for Immunohistochemistry on the Basis of Tyr-PCR , 2000, Annals of Surgical Oncology.

[30]  W. Steenbergen,et al.  Initial experiences in the photoacoustic detection of melanoma metastases in resected lymph nodes , 2011, BiOS.

[31]  Vasilis Ntziachristos,et al.  Quantitative Optoacoustic Signal Extraction Using Sparse Signal Representation , 2009, IEEE Transactions on Medical Imaging.

[32]  M. Catalano,et al.  Endosonographic features predictive of lymph node metastasis. , 1994, Gastrointestinal endoscopy.