Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior
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Wenzhen Duan | Mark P Mattson | Aiwu Cheng | M. Mattson | Zhihong Guo | Jaewon Lee | D. Gary | K. Furukawa | Sic L. Chan | W. Duan | A. Cheng | Jaewon Lee | Zhihong Guo | Katsutoshi Furukawa | N. Haughey | Sic L Chan | Devin S Gary | Norman Haughey
[1] W. Klapper,et al. Differential regulation of telomerase activity and TERT expression during brain development in mice , 2001, Journal of neuroscience research.
[2] J. Sloane,et al. Increased microglial activation and protein nitration in white matter of the aging monkey☆ , 1999, Neurobiology of Aging.
[3] E. Larson,et al. What's new in Alzheimer's disease treatment? Reasons for optimism about future pharmacologic options. , 1999, Postgraduate medicine.
[4] M. Dysken,et al. High doses of vitamin E in the treatment of disorders of the central nervous system in the aged. , 1999, The American journal of clinical nutrition.
[5] F R Sharp,et al. Increased Neurogenesis in the Dentate Gyrus After Transient Global Ischemia in Gerbils , 1998, The Journal of Neuroscience.
[6] M. Mattson,et al. Activation of K+ channels and suppression of neuronal activity by secreted β-amyloid-precursor protein , 1996, Nature.
[7] M. Mehler,et al. Developmental Changes in Progenitor Cell Responsiveness to Bone Morphogenetic Proteins Differentially Modulate Progressive CNS Lineage Fate , 2000, Developmental Neuroscience.
[8] A. Tobin,et al. Huntington's disease: the challenge for cell biologists. , 2000, Trends in cell biology.
[9] P. Praamstra,et al. Genetic and environmental risk factors in Parkinson’s disease , 1998, Clinical Neurology and Neurosurgery.
[10] Mark P. Mattson,et al. Calcium as sculptor and destroyer of neural circuitry , 1992, Experimental Gerontology.
[11] M. Mattson,et al. Beneficial Effects of Dietary Restriction on Cerebral Cortical Synaptic Terminals , 2000, Journal of neurochemistry.
[12] Eric J. Nestler,et al. Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus , 2000, The Journal of Neuroscience.
[13] M. Mattson,et al. Stem cells and aging: expanding the possibilities , 2001, Mechanisms of Ageing and Development.
[14] M. Mattson,et al. Telomerase protects developing neurons against DNA damage-induced cell death. , 2001, Brain research. Developmental brain research.
[15] P. Eriksson,et al. Enriched environment increases neurogenesis in the adult rat dentate gyrus and improves spatial memory. , 1999, Journal of neurobiology.
[16] J. Mcdonald,et al. Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord , 1999, Nature Medicine.
[17] F. Gage,et al. More hippocampal neurons in adult mice living in an enriched environment , 1997, Nature.
[18] M. Mattson,et al. Suppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: molecular mechanisms , 2001, Mechanisms of Ageing and Development.
[19] H Jick,et al. Statins and the risk of dementia , 2000, The Lancet.
[20] L. Mucke,et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein , 1995, Nature.
[21] J. Prehn,et al. Activation of Nuclear Factor κb and bcl-x Survival Gene Expression by Nerve Growth Factor Requires Tyrosine Phosphorylation of IκBα , 2001, The Journal of cell biology.
[22] R J Mark,et al. Amyloid β-Peptide Impairs Glucose Transport in Hippocampal and Cortical Neurons: Involvement of Membrane Lipid Peroxidation , 1997, The Journal of Neuroscience.
[23] M. Mattson,et al. Impairment of Glucose and Glutamate Transport and Induction of Mitochondrial Oxidative Stress and Dysfunction in Synaptosomes by Amyloid β‐Peptide: Role of the Lipid Peroxidation Product 4‐Hydroxynonenal , 1997, Journal of neurochemistry.
[24] J. Joseph,et al. Cellular and Molecular Mechanisms of Impaired Dopaminergic Function during Aging , 1994, Annals of the New York Academy of Sciences.
[25] M. Mattson,et al. Cyclosporin Ameliorates Traumatic Brain-Injury-Induced Alterations of Hippocampal Synaptic Plasticity , 2000, Experimental Neurology.
[26] J. Thome,et al. Advanced glycation endproducts in ageing and Alzheimer's disease , 1997, Brain Research Reviews.
[27] 谷垣 健二,et al. Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate , 2001 .
[28] N. Sousa,et al. Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement , 2000, Neuroscience.
[29] T. Saitoh,et al. Changes in Protein Kinases in Brain Aging and Alzheimer’s Disease , 1995, Drugs & Aging.
[30] Lye Tc,et al. Traumatic Brain Injury as a Risk Factor for Alzheimer's Disease: A Review , 2000, Neuropsychology Review.
[31] D. Hadler,et al. Sustained efficacy and safety of idebenone in the treatment of Alzheimer's disease: update on a 2-year double-blind multicentre study. , 1998, Journal of neural transmission. Supplementum.
[32] T. Omae. Stroke risk factors and stroke prevention. , 1992, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.
[33] E. Gould,et al. Neurogenesis in the adult is involved in the formation of trace memories , 2001, Nature.
[34] H. Przuntek,et al. Elevated Plasma Levels of Homocysteine inParkinson’s Disease , 1998, European Neurology.
[35] M. Hennerici,et al. Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[36] T. Palmer,et al. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[37] B STEINMANN,et al. [Aging and disease]. , 1963, Schweizerische medizinische Wochenschrift.
[38] S. Bondy,et al. Oxidative damage and cerebral aging , 1992, Progress in Neurobiology.
[39] Oxidative Alterations in Neurodegenerative Diseases , 2001 .
[40] D. Butterfield,et al. Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-α-phenylnitrone , 1997 .
[41] M. Mattson,et al. Secreted form of β‐amyloid precursor protein shifts the frequency dependency for induction of LTD, and enhances LTP in hippocampal slices , 1997, Neuroreport.
[42] U. Çakatay,et al. Relation of oxidative protein damage and nitrotyrosine levels in the aging rat brain , 2001, Experimental Gerontology.
[43] M. Gething. Role and regulation of the ER chaperone BiP. , 1999, Seminars in cell & developmental biology.
[44] M. Mattson,et al. Emerging roles for telomerase in regulating cell differentiation and survival: a neuroscientist's perspective , 2001, Mechanisms of Ageing and Development.
[45] M. Mattson,et al. Integrin signaling via the PI3‐kinase–Akt pathway increases neuronal resistance to glutamate‐induced apoptosis , 2001, Journal of neurochemistry.
[46] M. Mattson,et al. Folic Acid Deficiency and Homocysteine Impair DNA Repair in Hippocampal Neurons and Sensitize Them to Amyloid Toxicity in Experimental Models of Alzheimer's Disease , 2002, The Journal of Neuroscience.
[47] T. Morgan,et al. Chapter 10 Food Restriction and Brain Aging , 1997 .
[48] M. Mattson,et al. Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation , 1999, Brain Research.
[49] Scott Pollack,et al. Growth factors regulate the survival and fate of cells derived from human neurospheres , 2001, Nature Biotechnology.
[50] R Clarke,et al. Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. , 1998, Archives of neurology.
[51] E. Snyder,et al. "Global" cell replacement is feasible via neural stem cell transplantation: evidence from the dysmyelinated shiverer mouse brain. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[52] D. Lowenstein,et al. The stress protein response in cultured neurons: Characterization and evidence for a protective role in excitotoxicity , 1991, Neuron.
[53] P. Patterson,et al. Cytokine and Growth Factor Involvement in Long-Term Potentiation , 1999, Molecular and Cellular Neuroscience.
[54] C. Bergmann,et al. Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[55] M. Mattson,et al. 4‐Hydroxynonenal, an Aldehydic Product of Lipid Peroxidation, Impairs Signal Transduction Associated with Muscarinic Acetylcholine and Metabotropic Glutamate Receptors: Possible Action on Gαq/11 , 1997, Journal of neurochemistry.
[56] P. Amouyel,et al. Genetic susceptibility factors for Alzheimer's disease. , 2001, European journal of pharmacology.
[57] M. Mattson,et al. Dietary restriction and 2‐deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: Evidence for a preconditioning mechanism , 1999, Journal of neuroscience research.
[58] C. Altar. Neurotrophins and depression. , 1999, Trends in pharmacological sciences.
[59] M. Mattson,et al. Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[60] D. Ingram. Vaccine development for Alzheimer's disease: a shot of good news , 2001, Trends in Neurosciences.
[61] Todd B. Sherer,et al. Chronic systemic pesticide exposure reproduces features of Parkinson's disease , 2000, Nature Neuroscience.
[62] M. Mattson. Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adaptive plasticity , 1998, Trends in Neurosciences.
[63] J. Frydman. Folding of newly translated proteins in vivo: the role of molecular chaperones. , 2001, Annual review of biochemistry.
[64] G. Román,et al. Neuroepidemiology of amyotrophic lateral sclerosis: clues to aetiology and pathogenesis. , 1996, Journal of neurology, neurosurgery, and psychiatry.
[65] J. Bohl,et al. Immunohistochemical investigation of the brain of aged dogs. I. Detection of neurofibrillary tangles and of 4-hydroxynonenal protein, an oxidative damage product, in senile plaques , 2001, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.
[66] R. Weindruch,et al. Caloric Intake and Aging , 1997 .
[67] A. Björklund. Cell replacement strategies for neurodegenerative disorders. , 2000, Novartis Foundation symposium.
[68] M. Mattson,et al. The Endoplasmic Reticulum Stress-Responsive Protein GRP78 Protects Neurons Against Excitotoxicity and Apoptosis: Suppression of Oxidative Stress and Stabilization of Calcium Homeostasis , 1999, Experimental Neurology.
[69] M. Mattson,et al. Amyloid beta-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[70] S. Hoyer. Age-Related Changes in Cerebral Oxidative Metabolism , 1995, Drugs & aging.
[71] A. Ludolph. Treatment of amyotrophic lateral sclerosis - what is the next step? , 2000, Journal of neurology.
[72] Creatine: prescription for bad genes and a hostile environment? , 2000, Trends in Neurosciences.
[73] V Sossi,et al. PET studies of parkinsonism associated with mutation in the alpha-synuclein gene. , 1999, Neurology.
[74] Mark P. Mattson,et al. NF-κB in neuronal plasticity and neurodegenerative disorders , 2001 .
[75] Robert L. Nussbaum,et al. Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease , 1997 .
[76] R. Weindruch,et al. Dietary restriction benefits learning and motor performance of aged mice. , 1987, Journal of gerontology.
[77] M. Schwab. Regenerative Nerve Fiber Growth in the Adult Central Nervous System. , 1998, News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society.
[78] S. Estus,et al. Aggregated Amyloid-β Protein Induces Cortical Neuronal Apoptosis and Concomitant “Apoptotic” Pattern of Gene Induction , 1997, The Journal of Neuroscience.
[79] M. Mattson,et al. Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease. , 2002, Neuromolecular medicine.
[80] M. Mattson,et al. Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults , 1999, Annals of neurology.
[81] J. Morley,et al. Identification of age-dependent changes in expression of senescence-accelerated mouse (SAMP8) hippocampal proteins by expression array analysis. , 2000, Biochemical and biophysical research communications.
[82] M. Igarashi,et al. Decreased synaptic density in aged brains and its prevention by rearing under enriched environment as revealed by synaptophysin contents , 1994, Journal of neuroscience research.
[83] L A Beckett,et al. Education and other measures of socioeconomic status and risk of incident Alzheimer disease in a defined population of older persons. , 1997, Archives of neurology.
[84] Tasuku Honjo,et al. Notch1 and Notch3 Instructively Restrict bFGF-Responsive Multipotent Neural Progenitor Cells to an Astroglial Fate , 2001, Neuron.
[85] R. Weindruch,et al. Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging. , 1997, The New England journal of medicine.
[86] C. Culmsee,et al. Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity , 2000, The Journal of Neuroscience.
[87] Karen Marder,et al. Dietary lipids and antioxidants in Parkinson's disease: A population‐based, case‐control study , 1996, Annals of neurology.
[88] Mark P. Mattson,et al. Apoptosis in neurodegenerative disorders , 2000, Nature Reviews Molecular Cell Biology.
[89] M. Mattson,et al. A Role for 4‐Hydroxynonenal, an Aldehydic Product of Lipid Peroxidation, in Disruption of Ion Homeostasis and Neuronal Death Induced by Amyloid β‐Peptide , 1997, Journal of neurochemistry.
[90] D K Ingram,et al. What counts in brain aging? Design-based stereological analysis of cell number. , 1999, The journals of gerontology. Series A, Biological sciences and medical sciences.
[91] Heidi Phillips,et al. Mice Lacking α-Synuclein Display Functional Deficits in the Nigrostriatal Dopamine System , 2000, Neuron.
[92] B. Winblad,et al. CADASIL: hereditary disease of arteries causing brain infarcts and dementia , 1999, Neuropathology and applied neurobiology.
[93] S E Ide,et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. , 1997, Science.
[94] M. Mattson,et al. Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease , 2002, Journal of neurochemistry.
[95] B. Dobkin. Activity‐dependent learning contributes to motor recovery , 1998, Annals of neurology.
[96] M. Mattson,et al. Activation of NF‐κB protects hippocampal neurons against oxidative stress‐induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration , 1997, Journal of neuroscience research.
[97] J. Stamler,et al. S-nitrosylation: spectrum and specificity , 2001, Nature Cell Biology.
[98] F. Gage,et al. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus , 1999, Nature Neuroscience.
[99] D. Sulzer,et al. Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. , 2000, Neuron.
[100] M. Mattson,et al. A Mechanism for the Neuroprotective Effect of Apolipoprotein E , 2000, Journal of neurochemistry.
[101] Miles W. Miller,et al. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice , 1999, Nature Medicine.
[102] Vesna Sossi,et al. Prevalence of epilepsy in rural Bolivia , 1999, Neurology.
[103] C. Pozniak,et al. Neuronal life and death: an essential role for the p53 family , 2000, Cell Death and Differentiation.
[104] Zhiming Zhang,et al. Neuroprotective and neurorestorative properties of GDNF , 1998, Annals of neurology.
[105] R. S. Sohal,et al. Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of the mouse. , 1996, Archives of biochemistry and biophysics.
[106] M. Mattson,et al. Dietary restriction and 2‐deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease , 1999, Journal of neuroscience research.
[107] K. Chandross,et al. Bone marrow: a possible alternative source of cells in the adult nervous system. , 2000, European journal of pharmacology.
[108] M. Mattson,et al. Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat‐shock proteins and Bcl‐2 , 2001, Journal of neurochemistry.
[109] A. Granholm,et al. Long-Term Environmental Enrichment Leads to Regional Increases in Neurotrophin Levels in Rat Brain , 2000, Experimental Neurology.
[110] M. Citron. Secretases as targets for the treatment of Alzheimer's disease. , 2000, Molecular medicine today.
[111] M. Mattson,et al. Neurotrophic factors protect cortical synaptic terminals against amyloid and oxidative stress-induced impairment of glucose transport, glutamate transport and mitochondrial function. , 2000, Cerebral cortex.
[112] S. Minoshima,et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism , 1998, Nature.
[113] W. Meier-Ruge,et al. Synaptic structural dynamics and aging. , 1996, Gerontology.
[114] Richard Weindruch,et al. Gene-expression profile of the ageing brain in mice , 2000, Nature Genetics.
[115] C. Culmsee,et al. A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β‐peptide , 2001 .
[116] M. Mattson. Neuroprotective Signal Transduction: Relevance to Stroke , 1997, Neuroscience & Biobehavioral Reviews.
[117] M. Mattson,et al. Neurotrophic Factors Attenuate Glutamate‐Induced Accumulation of Peroxides, Elevation of Intracellular Ca2+ Concentration, and Neurotoxicity and Increase Antioxidant Enzyme Activities in Hippocampal Neurons , 1995, Journal of neurochemistry.
[118] M. Mattson,et al. Secreted Form of Amyloid Precursor Protein Enhances Basal Glucose and Glutamate Transport and Protects Against Oxidative Impairment of Glucose and Glutamate Transport in Synaptosomes by a Cyclic GMP‐Mediated Mechanism , 1999, Journal of neurochemistry.
[119] J. Lowenthal,et al. The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neurons , 1999, Nature Neuroscience.
[120] E. A. Shores,et al. Traumatic Brain Injury as a Risk Factor for Alzheimer's Disease: A Review , 2004, Neuropsychology Review.
[121] P. Jenner,et al. Understanding cell death in parkinson's disease , 1998, Annals of neurology.
[122] M. Greenberg,et al. Neurogenin Promotes Neurogenesis and Inhibits Glial Differentiation by Independent Mechanisms , 2001, Cell.
[123] R. S. Sohal,et al. Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice , 1994, Mechanisms of Ageing and Development.
[124] J. Jankovic,et al. Variability and validity of polymorphism association studies in Parkinson’s disease , 2000, Neurology.
[125] M. Mattson. Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives. , 1997, Physiological reviews.
[126] Genetic polymorphisms in Parkinson's disease. , 1998, Neurotoxicology.
[127] F. Gage,et al. Mammalian neural stem cells. , 2000, Science.
[128] D. Butterfield,et al. Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[129] Vladimir V. Frolkis,et al. Neurobiology of Aging , 2019, Psychobiology of Behaviour.
[130] M. Mattson,et al. Brain‐derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice , 2001, Journal of neurochemistry.
[131] W. Abraham,et al. Immediate early gene transcription and synaptic modulation , 1999, Journal of neuroscience research.