The Endothelium, Part I: Multiple Functions of the Endothelial Cells -- Focus on Endothelium-Derived Vasoactive Mediators
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[1] M. Goligorsky,et al. Dual Pathways of Carbon Monoxide–Mediated Vasoregulation: Modulation by Redox Mechanisms , 2009, Circulation research.
[2] T. Bonner,et al. Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[3] H. Kuhn,et al. Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications. , 2002, Prostaglandins & other lipid mediators.
[4] M. Worthley,et al. Vasopeptidase inhibitors: will they have a role in clinical practice? , 2003, British journal of clinical pharmacology.
[5] D. Fulton,et al. Evidence against a cytochrome P450-derived reactive oxygen species as the mediator of the nitric oxide-independent vasodilator effect of bradykinin in the perfused heart of the rat. , 1997, The Journal of pharmacology and experimental therapeutics.
[6] L. Rossoni,et al. Aldosterone induces endothelial dysfunction in resistance arteries from normotensive and hypertensive rats by increasing thromboxane A2 and prostacyclin , 2008, British journal of pharmacology.
[7] K. Desai,et al. EDHF-mediated rapid restoration of hypotensive response to acetylcholine after chronic, but not acute, nitric oxide synthase inhibition in rats. , 2006, European journal of pharmacology.
[8] Rui Wang,et al. The Chemical Modification of KCa Channels by Carbon Monoxide in Vascular Smooth Muscle Cells* , 1997, The Journal of Biological Chemistry.
[9] E. Canet,et al. Different Involvement of Nitric Oxide in Endothelium‐Dependent Relaxation of Porcine Pulmonary Artery and Vein: Influence of Hypoxia , 1995, Journal of cardiovascular pharmacology.
[10] K. Shinozuka,et al. In vitro studies of release of adenine nucleotides and adenosine from rat vascular endothelium in response to α1‐adrenoceptor stimulation , 1994, British journal of pharmacology.
[11] A. Mele,et al. Proteolytic processing of big endothelin-3 by the kell blood group protein. , 1999, Blood.
[12] A. Nicolosi,et al. Diabetes Mellitus Impairs Vasodilation to Hypoxia in Human Coronary Arterioles: Reduced Activity of ATP-Sensitive Potassium Channels , 2003, Circulation research.
[13] J. Linden,et al. Modulation of guanylate cyclase by lipoxygenase inhibitors. , 1986, Hypertension.
[14] Lingyun Wu,et al. Carbon Monoxide: Endogenous Production, Physiological Functions, and Pharmacological Applications , 2005, Pharmacological Reviews.
[15] W. Campbell,et al. Endothelial 15-Lipoxygenase-1 Overexpression Increases Acetylcholine-Induced Hypotension and Vasorelaxation in Rabbits , 2008, Hypertension.
[16] J. Mbanya,et al. Anti-inflammatory activity of erycristagallin, a pterocarpene from Erythrina mildbraedii. , 2003, European journal of pharmacology.
[17] M. Hollenberg,et al. Multiple mechanisms of vascular smooth muscle relaxation by the activation of Proteinase‐Activated Receptor 2 in mouse mesenteric arterioles , 2002, British journal of pharmacology.
[18] C. Bode,et al. Impaired Endogenous Fibrinolysis in Diabetes Mellitus: Mechanisms and Therapeutic Approaches , 2000, Seminars in thrombosis and hemostasis.
[19] J. Morrow,et al. Acetylcholine‐induced endothelium‐dependent contractions in the SHR aorta: the Janus face of prostacyclin , 2005, British journal of pharmacology.
[20] S. Sage,et al. Calcium‐activated potassium channels in the endothelium of intact rat aorta. , 1996, The Journal of physiology.
[21] S. Snyder,et al. Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase , 1991, Nature.
[22] L. Rosenfeld,et al. Contribution of endothelin to the acute pressor response of L-NAME in stroke-prone spontaneously hypertensive rats. , 1998, Journal of cardiovascular pharmacology.
[23] Pál Pacher,et al. Cannabinoid‐1 receptor activation induces reactive oxygen species‐dependent and ‐independent mitogen‐activated protein kinase activation and cell death in human coronary artery endothelial cells , 2010, British journal of pharmacology.
[24] K. Komori,et al. Electrical Responses of Smooth Muscle Cells During Cholinergic Vasodilation in the Rabbit Saphenous Artery , 1987, Circulation research.
[25] C. Triggle,et al. Endothelium-derived reactive oxygen species: their relationship to endothelium-dependent hyperpolarization and vascular tone. , 2003, Canadian journal of physiology and pharmacology.
[26] C. Wit,et al. The endothelium at the brink of calamity in storage disease: more than just overloaded with junk? , 2011, Cardiovascular research.
[27] T. Lincoln,et al. Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression. , 2001, Journal of applied physiology.
[28] D. Gutterman,et al. The mechanism of flow-induced dilation in human adipose arterioles involves hydrogen peroxide during CAD. , 2007, American journal of physiology. Heart and circulatory physiology.
[29] J. B. Salom,et al. Impairment of the modulatory role of nitric oxide on the endothelin-1-elicited contraction of cerebral arteries: a pathogenetic factor in cerebral vasospasm after subarachnoid hemorrhage? , 1997, Neurosurgery.
[30] A. Dominiczak,et al. Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats , 2002, Journal of hypertension.
[31] Y. Sasaguri,et al. Nitric Oxide Synthases and Cardiovascular Diseases , 2009 .
[32] Du Junbao,et al. Nitric Oxide Impacts Endothelin-1 Gene Expression in Intrapulmonary Arteries of Chronically Hypoxic Rats , 1999, Angiology.
[33] J. Mcgiff,et al. Is EDHF an epoxyeicosatrienoic acid? , 2000, Trends in pharmacological sciences.
[34] V. Ullrich,et al. Endotoxin elicits nitric oxide release in rat but prostacyclin synthesis in human and bovine vascular smooth muscle cells. , 2005, Biochemical and biophysical research communications.
[35] D. Fulton,et al. Pharmacological evaluation of an epoxide as the putative hyperpolarizing factor mediating the nitric oxide-independent vasodilator effect of bradykinin in the rat heart. , 1998, The Journal of pharmacology and experimental therapeutics.
[36] R. Tabrizchi,et al. Pharmacology of adenosine receptors in the vasculature. , 2001, Pharmacology & therapeutics.
[37] Rui Wang,et al. Carbon monoxide‐induced vasorelaxation and the underlying mechanisms , 1997, British journal of pharmacology.
[38] T. Iwamoto,et al. Differential inhibition of Na+/Ca2+exchanger isoforms by divalent cations and isothiourea derivative. , 1998, American journal of physiology. Cell physiology.
[39] H. Kim,et al. Activation of K+ channel in vascular smooth muscles by cytochrome P450 metabolites of arachidonic acid. , 1993, European journal of pharmacology.
[40] David John Adams,et al. Potassium Channels and Membrane Potential in the Modulation of Intracellular Calcium in Vascular Endothelial Cells , 2004, Journal of cardiovascular electrophysiology.
[41] D. Altavilla,et al. Protective effects of BAY U 3405, a thromboxane A2 receptor antagonist, in endotoxin shock. , 1994, Pharmacological research.
[42] D. Kass,et al. Phosphodiesterase regulation of nitric oxide signaling. , 2007, Cardiovascular research.
[43] O. Schaad,et al. An evaluation of potassium ions as endothelium‐derived hyperpolarizing factor in porcine coronary arteries , 2000, British journal of pharmacology.
[44] R. Busse,et al. Characterization of the endothelium-derived hyperpolarizing factor (EDHF) response in the human interlobar artery. , 2003, Kidney international.
[45] Yuzhi Zhang,et al. Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype. , 2010, Cardiovascular research.
[46] S. Steffens,et al. The emerging role of the endocannabinoid system in cardiovascular disease , 2009, Seminars in Immunopathology.
[47] H. Parkington,et al. In vivo regulation of endothelium-dependent vasodilation in the rat renal circulation and the effect of streptozotocin-induced diabetes. , 2008, American journal of physiology. Regulatory, integrative and comparative physiology.
[48] T. Michel,et al. Expression of constitutive endothelial nitric oxide synthase in human blood platelets. , 1995, Life sciences.
[49] D. Edwards,et al. cAMP facilitates EDHF-type relaxations in conduit arteries by enhancing electrotonic conduction via gap junctions , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[50] C. Johnston,et al. ACE2, a new regulator of the renin–angiotensin system , 2004, Trends in Endocrinology & Metabolism.
[51] A. Briones,et al. Hypertension Increases Contractile Responses to Hydrogen Peroxide in Resistance Arteries through Increased Thromboxane A2, Ca2+, and Superoxide Anion Levels , 2009, Journal of Pharmacology and Experimental Therapeutics.
[52] J. Stasch,et al. NO- and haem-independent soluble guanylate cyclase activators. , 2009, Handbook of experimental pharmacology.
[53] M. Frieden,et al. Epoxyeicosatrienoic acids activate a high‐conductance, Ca2+‐dependent K+ channel on pig coronary artery endothelial cells , 1997, The Journal of physiology.
[54] J. Morrow,et al. A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[55] W. Durante,et al. Role of carbon monxide in cardiovascular function , 2006, Journal of cellular and molecular medicine.
[56] K. Malik,et al. Mechanism of vascular actions of prostacyclin in the rat isolated perfused mesenteric arteries. , 1990, The Journal of pharmacology and experimental therapeutics.
[57] M. Ujhelyi,et al. Impaired Endothelium-Mediated Relaxation in Coronary Arteries from Insulin-Resistant Rats1 , 1999, Journal of Vascular Research.
[58] Lingyun Wu,et al. Different mechanisms underlying the stimulation of K(Ca) channels by nitric oxide and carbon monoxide. , 2002, The Journal of clinical investigation.
[59] Paul L Huang,et al. Accelerated Atherosclerosis, Aortic Aneurysm Formation, and Ischemic Heart Disease in Apolipoprotein E/Endothelial Nitric Oxide Synthase Double-Knockout Mice , 2001, Circulation.
[60] K. Cruickshank,et al. Small vessel remodeling and impaired endothelial-dependent dilatation in subcutaneous resistance arteries from patients with acromegaly. , 2007, The Journal of clinical endocrinology and metabolism.
[61] D. Bani,et al. Mechanical stretch reveals different components of endothelial‐mediated vascular tone in rat aortic strips , 2000, British journal of pharmacology.
[62] J. Chin-Dusting,et al. Insulin Inhibits Acetylcholine Responses in Rat Isolated Mesenteric Arteries via a Non-Nitric Oxide Nonprostanoid Pathway , 2002, HYPERTENSION.
[63] A. Weston,et al. Impaired small‐conductance Ca2+‐activated K+ channel‐dependent EDHF responses in Type II diabetic ZDF rats , 2006, British journal of pharmacology.
[64] T. W. Secomb,et al. The endothelial surface layer , 2000, Pflügers Archiv.
[65] A. Quyyumi,et al. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. , 1990, The New England journal of medicine.
[66] J. Folkman,et al. Blood Vessel Formation: What Is Its Molecular Basis? , 1996, Cell.
[67] K. Heygate,et al. Impaired endothelium‐dependent relaxation in isolated resistance arteries of spontaneously diabetic rats , 1995, British journal of pharmacology.
[68] N. Rusch,et al. Freshly isolated bovine coronary endothelial cells do not express the BKca channel gene , 2002, The Journal of physiology.
[69] R. Aldrich,et al. Vasoregulation by the β1 subunit of the calcium-activated potassium channel , 2000, Nature.
[70] W. Aird,et al. The endothelium and thrombosis. , 2000, Seminars in thrombosis and hemostasis.
[71] P. Vallance,et al. Biological significance of endogenous methylarginines that inhibit nitric oxide synthases. , 1999, Cardiovascular research.
[72] I. Song,et al. The enzymology of prostaglandin endoperoxide H synthases-1 and -2. , 2002, Prostaglandins & other lipid mediators.
[73] A. Shoukas,et al. Endothelial Arginase II: A Novel Target for the Treatment of Atherosclerosis , 2008, Circulation research.
[74] P. Vanhoutte,et al. EDHF: new therapeutic targets? , 2004, Pharmacological research.
[75] J. Stasch,et al. Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels. , 2006, The Journal of clinical investigation.
[76] Y. Hellsten,et al. Vasodilatory mechanisms in contracting skeletal muscle. , 2004, Journal of applied physiology.
[77] E. Hamel,et al. Expression of Neuropeptide Y Receptors mRNA and Protein in Human Brain Vessels and Cerebromicrovascular Cells in Culture , 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[78] E. Dejana,et al. Perspectives Series: Cell Adhesion in Vascular Biology Endothelial Adherens Junctions: Implications in the Control of Vascular Permeability and Angiogenesis , 1996 .
[79] W. Beierwaltes,et al. Distinct hydrogen peroxide-induced constriction in multiple mouse arteries: potential influence of vascular polarization. , 2008, Pharmacological reports : PR.
[80] R. Webb,et al. Reduced expression of SKCa and IKCa channel proteins in rat small mesenteric arteries during angiotensin II-induced hypertension. , 2007, American journal of physiology. Heart and circulatory physiology.
[81] S. Narumiya,et al. Stimulation of renin release by prostaglandin E2 is mediated by EP2 and EP4 receptors in mouse kidneys. , 2004, American journal of physiology. Renal physiology.
[82] L. Otterbein,et al. The therapeutic potential of carbon monoxide , 2010, Nature Reviews Drug Discovery.
[83] P. Vanhoutte,et al. Endothelium-Dependent Hyperpolarization to Acetylcholine in Carotid Artery of Guinea Pig: Role of Lipoxygenase , 2002, Journal of cardiovascular pharmacology.
[84] W. Campbell,et al. Endothelium-dependent contractions in rabbit pulmonary artery are mediated by thromboxane A2. , 1993, Circulation research.
[85] R. Sprague,et al. Cyclooxygenase (COX)-1 and COX-2 Participate in 5,6-Epoxyeicosatrienoic Acid-Induced Contraction of Rabbit Intralobar Pulmonary Arteries , 2007, Journal of Pharmacology and Experimental Therapeutics.
[86] S. Moncada,et al. Nitric oxide and mitochondrial signaling: from physiology to pathophysiology. , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[87] M. Lewis,et al. The nature of endothelium-derived vascular relaxant factor , 1984, Nature.
[88] K. Kangawa,et al. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. , 1993, Biochemical and biophysical research communications.
[89] K. Boussery,et al. Control of Retinal Arterial Tone by a Paracrine Retinal Relaxing Factor , 2007, Microcirculation.
[90] J. Falck,et al. Effects of a 20-HETE antagonist and agonists on cerebral vascular tone. , 2004, European journal of pharmacology.
[91] C. Garland,et al. Spreading dilatation in rat mesenteric arteries associated with calcium‐independent endothelial cell hyperpolarization , 2004, The Journal of physiology.
[92] Guangju Ji,et al. PECAM-1 (CD31) regulates a hydrogen peroxide–activated nonselective cation channel in endothelial cells , 2002, The Journal of cell biology.
[93] W. Liedtke,et al. Transient Receptor Potential Vanilloid 4–Mediated Disruption of the Alveolar Septal Barrier: A Novel Mechanism of Acute Lung Injury , 2006, Circulation research.
[94] V. Lemos,et al. Neuronal nitric oxide synthase-derived hydrogen peroxide is a major endothelium-dependent relaxing factor. , 2008, American journal of physiology. Heart and circulatory physiology.
[95] A. Yim,et al. Different Role of Nitric Oxide and Endothelium-Derived Hyperpolarizing Factor in Endothelium-Dependent Hyperpolarization and Relaxation in Porcine Coronary Arterial and Venous System , 2004, Journal of cardiovascular pharmacology.
[96] C. Garland,et al. Small‐ and Intermediate‐Conductance Calcium‐Activated K+ Channels Provide Different Facets of Endothelium‐Dependent Hyperpolarization in Rat Mesenteric Artery , 2003, The Journal of physiology.
[97] Yi-chang Jia,et al. Blockage of intermediate-conductance-Ca2+-activated K+ channels inhibits progression of human endometrial cancer , 2007, Oncogene.
[98] A M Zeiher,et al. Endothelium-mediated coronary blood flow modulation in humans. Effects of age, atherosclerosis, hypercholesterolemia, and hypertension. , 1993, The Journal of clinical investigation.
[99] S. Taddei,et al. Endothelial dysfunction in essential hypertension: clinical implications. , 2002, Journal of hypertension.
[100] T. Griffith,et al. Relative contributions of NO and gap junctional communication to endothelium-dependent relaxations of rabbit resistance arteries vary with vessel size. , 2002, Microvascular research.
[101] P. Kubes,et al. Acetylcholine‐induced relaxation of peripheral arteries isolated from mice lacking endothelial nitric oxide synthase , 1999, British journal of pharmacology.
[102] J. Hwa,et al. Versatility and Differential Roles of Cysteine Residues in Human Prostacyclin Receptor Structure and Function* , 2006, Journal of Biological Chemistry.
[103] Michael Chinkers,et al. Cyclic Nucleotide-gated Channels Mediate Membrane Depolarization following Activation of Store-operated Calcium Entry in Endothelial Cells* , 2000, The Journal of Biological Chemistry.
[104] J. Cohn. Role of the Renin-Angiotensin System in Cardiovascular Disease , 2010, Cardiovascular Drugs and Therapy.
[105] G. Norata,et al. HDL3 induces cyclooxygenase-2 expression and prostacyclin release in human endothelial cells via a p38 MAPK/CRE-dependent pathway: effects on COX-2/PGI-synthase coupling. , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[106] J. Falck,et al. 11(R),12(S),15(S)-trihydroxyeicosa-5(Z),8(Z),13(E)-trienoic acid: an endothelium-derived 15-lipoxygenase metabolite that relaxes rabbit aorta. , 2008, American journal of physiology. Heart and circulatory physiology.
[107] R. Hammer,et al. Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene. , 1998, Development.
[108] Wei Zhang,et al. Communication between malignant glioma cells and vascular endothelial cells through gap junctions. , 2003, Journal of Neurosurgery.
[109] R. Sprague,et al. Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit. , 2003, American journal of physiology. Heart and circulatory physiology.
[110] F. Faraci,et al. Endothelium-Derived Hyperpolarizing Factor: Where Are We Now? , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[111] D. Edwards,et al. Gap junction-dependent increases in smooth muscle cAMP underpin the EDHF phenomenon in rabbit arteries. , 2001, Biochemical and biophysical research communications.
[112] U. Förstermann,et al. Antiatherosclerotic Effects of Small-Molecular-Weight Compounds Enhancing Endothelial Nitric-Oxide Synthase (eNOS) Expression and Preventing eNOS Uncoupling , 2008, Journal of Pharmacology and Experimental Therapeutics.
[113] H. Ishizaki,et al. Incidence of Sex Chromatin in Gallus domesticus , 1959, Science.
[114] I. Grgic,et al. Evidence for a Functional Role of Endothelial Transient Receptor Potential V4 in Shear Stress–Induced Vasodilatation , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[115] M. Kähönen,et al. Endothelial function in deoxycorticosterone-NaCl hypertension: effect of calcium supplementation. , 1996, Circulation.
[116] E. Levin,et al. Atrial and brain natriuretic peptides stimulate the production and secretion of C-type natriuretic peptide from bovine aortic endothelial cells. , 1995, The Journal of clinical investigation.
[117] B. Fisslthaler,et al. Activation and signaling by the AMP-activated protein kinase in endothelial cells. , 2009, Circulation research.
[118] C. Shih,et al. ABNORMAL ACTIVATION OF POTASSIUM CHANNELS IN AORTIC SMOOTH MUSCLE OF RATS WITH PERITONITIS-INDUCED SEPTIC SHOCK , 2009, Shock.
[119] C. Arroyo,et al. Endothelial cells as a source of oxygen-free radicals. An ESR study. , 1990, Free radical research communications.
[120] Richard P. White,et al. A comparison of EDHF‐mediated and anandamide‐induced relaxations in the rat isolated mesenteric artery , 1997, British journal of pharmacology.
[121] A. Suburo,et al. Development of the endothelium. , 2006, Handbook of experimental pharmacology.
[122] S. Moncada,et al. The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide , 1987, British journal of pharmacology.
[123] A. Hobbs,et al. C-type natriuretic peptide (CNP): cardiovascular roles and potential as a therapeutic target. , 2010, Current pharmaceutical design.
[124] J. Stasch,et al. Mechanisms of nitric oxide independent activation of soluble guanylyl cyclase. , 2003, European journal of pharmacology.
[125] J. van de Voorde,et al. Influence of some phospholipase A2 and cytochrome P450 inhibitors on rat arterial smooth muscle K+ currents. , 1999, Canadian journal of physiology and pharmacology.
[126] B. Duling,et al. Endothelial cell-specific knockout of connexin 43 causes hypotension and bradycardia in mice , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[127] S. Heinemann,et al. Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels , 2003, Nature.
[128] M. Gollasch,et al. Cyclooxygenase-2–Derived Prostaglandin F2&agr; Mediates Endothelium-Dependent Contractions in the Aortae of Hamsters With Increased Impact During Aging , 2009, Circulation research.
[129] R. Marthan,et al. Hypoxia-induced hyperreactivity of pulmonary arteries: role of cyclooxygenase-2, isoprostanes, and thromboxane receptors. , 2010, Cardiovascular research.
[130] K. Tanzawa,et al. Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[131] K. So,et al. Calcium and reactive oxygen species increase in endothelial cells in response to releasers of endothelium‐derived contracting factor , 2007, British journal of pharmacology.
[132] J. van de Voorde,et al. Effects of connexin-mimetic peptides on nitric oxide synthase- and cyclooxygenase-independent renal vasodilation. , 2002, Kidney international.
[133] R. Köhler,et al. Up-regulation of endothelial stretch-activated cation channels by fluid shear stress. , 2002, Cardiovascular research.
[134] A. Salvetti,et al. Vasodilation to acetylcholine in primary and secondary forms of human hypertension. , 1993, Hypertension.
[135] W. Lederer,et al. Calcium sparks in smooth muscle. , 2000, American journal of physiology. Cell physiology.
[136] R. Roman,et al. Role of cytochrome P450 metabolites of arachidonic acid in hypertension. , 2004, Current drug metabolism.
[137] M. Hollenberg,et al. Hyperpolarization of murine small caliber mesenteric arteries by activation of endothelial proteinase-activated receptor 2. , 2004, Canadian journal of physiology and pharmacology.
[138] D. Edwards,et al. Distinct hyperpolarizing and relaxant roles for gap junctions and endothelium-derived H2O2 in NO-independent relaxations of rabbit arteries , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[139] Hua Cai,et al. Role of p47phox in Vascular Oxidative Stress and Hypertension Caused by Angiotensin II , 2002, Hypertension.
[140] B. Lévy,et al. Altered TP receptor function in isolated, perfused kidneys of nondiabetic and diabetic ApoE-deficient mice. , 2008, American journal of physiology. Renal physiology.
[141] R. Berne,et al. Differential Effects of Adenosine and Nitroglycerin on the Action Potentials of Large and Small Coronary Arteries , 1979, Circulation research.
[142] J. Simard,et al. Multiple connexins form gap junction channels in rat basilar artery smooth muscle cells. , 1999, Circulation research.
[143] R. Breyer,et al. Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. , 2004, Pharmacology & therapeutics.
[144] M. Lazdunski,et al. Altered acetylcholine, bradykinin and cutaneous pressure‐induced vasodilation in mice lacking the TREK1 potassium channel: the endothelial link , 2007, EMBO reports.
[145] M. Félétou. Calcium‐activated potassium channels and endothelial dysfunction: therapeutic options? , 2009, British journal of pharmacology.
[146] N. Bissoli,et al. Endothelial mediators of 17 beta-estradiol-induced coronary vasodilation in the isolated rat heart. , 2004, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
[147] T. Itoh,et al. Acetylcholine‐induced membrane potential changes in endothelial cells of rabbit aortic valve , 1999, British journal of pharmacology.
[148] B. T. Altura,et al. Mechanisms of hydrogen peroxide-induced contraction of rat aorta. , 1998, European journal of pharmacology.
[149] Richard G. W. Anderson,et al. Caveolin, a protein component of caveolae membrane coats , 1992, Cell.
[150] R. Touyz. Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance? , 2004, Hypertension.
[151] P. Lory,et al. Direct inhibition of T‐type calcium channels by the endogenous cannabinoid anandamide , 2001, The EMBO journal.
[152] S. Moncada,et al. Vascular endothelial cells synthesize nitric oxide from L-arginine , 1988, Nature.
[153] S. Heinemann,et al. Heme Regulates Allosteric Activation of the Slo1 BK Channel , 2005, The Journal of general physiology.
[154] J. Sainz,et al. Gender difference in the role of endothelium-derived relaxing factors modulating renal vascular reactivity. , 2004, European journal of pharmacology.
[155] T. Pauyo,et al. TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure. , 2009, American journal of physiology. Heart and circulatory physiology.
[156] T. Griffith,et al. Central role of heterocellular gap junctional communication in endothelium‐dependent relaxations of rabbit arteries , 1998, The Journal of physiology.
[157] F. Murad,et al. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[158] P. Vanhoutte,et al. Potentiation of endothelium-dependent relaxations to bradykinin by angiotensin I converting enzyme inhibitors in canine coronary artery involves both endothelium-derived relaxing and hyperpolarizing factors. , 1992, Circulation research.
[159] A. Habib,et al. Cyclo‐oxygenase‐1 and −2 contribution to endothelial dysfunction in ageing , 2000, British journal of pharmacology.
[160] C. Haudenschild,et al. Endothelin, hypercholesterolemia and atherosclerosis. , 2003, Coronary artery disease.
[161] K. Ishikawa. Heme oxygenase-1 against vascular insufficiency: roles of atherosclerotic disorders. , 2003, Current pharmaceutical design.
[162] Stephen J. Wilson,et al. Dimerization of the Human Receptors for Prostacyclin and Thromboxane Facilitates Thromboxane Receptor-mediated cAMP Generation* , 2004, Journal of Biological Chemistry.
[163] L. Blatter,et al. Capacitative Ca2+ entry is graded with degree of intracellular Ca2+ store depletion in bovine vascular endothelial cells , 2000, The Journal of physiology.
[164] X. Tian,et al. 4-aminopyridine-sensitive K+ channels contributes to NaHS-induced membrane hyperpolarization and relaxation in the rat coronary artery. , 2010, Vascular pharmacology.
[165] David John Adams,et al. Calcium‐activated potassium channels in native endothelial cells from rabbit aorta: conductance, Ca2+ sensitivity and block. , 1992, The Journal of physiology.
[166] P. Vanhoutte,et al. Status of the endothelium-derived hyperpolarizing factor pathway in coronary arteries after heterotopic heart transplantation. , 2007, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
[167] S. Moncada,et al. Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets , 1987, British journal of pharmacology.
[168] C. Thuillez,et al. ROLE OF ENDOTHELIUM‐DERIVED HYPERPOLARIZING FACTOR IN THE REGULATION OF RADIAL ARTERY BASAL DIAMETER AND ENDOTHELIUM‐DEPENDENT DILATATION IN VIVO , 2008, Clinical and experimental pharmacology & physiology.
[169] P. Båvenholm,et al. Enhanced Endothelium-dependent Vasodilatation by Dual Endothelin Receptor Blockade in Individuals With Insulin Resistance , 2006, Journal of cardiovascular pharmacology.
[170] K. Willecke,et al. Endothelium‐specific replacement of the connexin43 coding region by a lacZ reporter gene , 2001, Genesis.
[171] R. Cohen,et al. The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis. , 2000, Arteriosclerosis, thrombosis, and vascular biology.
[172] J. Vilaine,et al. Impairment of G-protein-mediated signal transduction in the porcine coronary endothelium during rejection after heart transplantation. , 1999, Cardiovascular research.
[173] J. Falck,et al. Stable 5,6-Epoxyeicosatrienoic Acid Analog Relaxes Coronary Arteries Through Potassium Channel Activation , 2005, Hypertension.
[174] Yasuo Ogasawara,et al. Hydrogen Peroxide, an Endogenous Endothelium-Derived Hyperpolarizing Factor, Plays an Important Role in Coronary Autoregulation In Vivo , 2003, Circulation.
[175] R. Busse,et al. Modulation of the Ca2 Permeable Cation Channel TRPV4 by Cytochrome P450 Epoxygenases in Vascular Endothelium , 2005, Circulation research.
[176] P. Vanhoutte,et al. Epoxyeicosatrienoic acids, potassium channel blockers and endothelium‐dependent hyperpolarization in the guinea‐pig carotid artery , 1998, British journal of pharmacology.
[177] Richard Graham Knowles,et al. Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[178] D. Strøbæk,et al. Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+‐activated K+ channels , 2007, British journal of pharmacology.
[179] Masashi Yanagisawa,et al. A missense mutation of the endothelin-B receptor gene in multigenic hirschsprung's disease , 1994, Cell.
[180] Shinn-Zong Lin,et al. Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion , 2008, Proceedings of the National Academy of Sciences.
[181] D. Rader,et al. COX-2-Derived Prostacyclin Confers Atheroprotection on Female Mice , 2004, Science.
[182] J. Falck,et al. Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase. , 2000, Journal of lipid research.
[183] P. Needleman,et al. Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase). , 1988, The Journal of biological chemistry.
[184] S. Narumiya,et al. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor , 1997, Nature.
[185] T. Benzing,et al. Angiotensin-converting enzyme inhibitor ramiprilat interferes with the sequestration of the B2 kinin receptor within the plasma membrane of native endothelial cells. , 1999, Circulation.
[186] W. Hsueh,et al. Peroxisome proliferator-activated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction. , 1999, Arteriosclerosis, thrombosis, and vascular biology.
[187] A. Takeshita,et al. Short-term estrogen augments both nitric oxide-mediated and non-nitric oxide-mediated endothelium-dependent forearm vasodilation in postmenopausal women. , 1997, Journal of cardiovascular pharmacology.
[188] W. Campbell,et al. Apamin-Sensitive K+ Currents Mediate Arachidonic Acid-Induced Relaxations of Rabbit Aorta , 2004, Hypertension.
[189] W. Seeger,et al. Impact of TASK-1 in Human Pulmonary Artery Smooth Muscle Cells , 2006, Circulation research.
[190] P. Baker,et al. The role of gap junctions in mediating endothelium‐dependent responses to bradykinin in myometrial small arteries isolated from pregnant women , 2002, British journal of pharmacology.
[191] J. Nicolas,et al. NPY receptor subtype in the rabbit isolated ileum , 1999, British journal of pharmacology.
[192] J. Petrie,et al. AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease , 2009, Clinical science.
[193] M. Schwartzman,et al. Heme Oxygenase-2 Deletion Causes Endothelial Cell Activation Marked by Oxidative Stress, Inflammation, and Angiogenesis , 2009, Journal of Pharmacology and Experimental Therapeutics.
[194] D. Ward,et al. The expression and function of Ca2+‐sensing receptors in rat mesenteric artery; comparative studies using a model of type II diabetes , 2008, British journal of pharmacology.
[195] S. Sandow,et al. Rapid Endothelial Cell–Selective Loading of Connexin 40 Antibody Blocks Endothelium-Derived Hyperpolarizing Factor Dilation in Rat Small Mesenteric Arteries , 2005, Circulation research.
[196] T. Bolton. Mechanisms of action of transmitters and other substances on smooth muscle. , 1979, Physiological reviews.
[197] R. E. Berson,et al. Role of Shear Stress in Endothelial Cell Morphology and Expression of Cyclooxygenase Isoforms , 2011, Arteriosclerosis, thrombosis, and vascular biology.
[198] C. Giannarelli,et al. Atorvastatin Prevents Endothelial Dysfunction in Mesenteric Arteries From Spontaneously Hypertensive Rats: Role of Cyclooxygenase 2–Derived Contracting Prostanoids , 2009, Hypertension.
[199] A. Ishisaki,et al. Autocrine endothelial regulation in brain stem vessels of newborn piglets. , 1999, Histology and histopathology.
[200] P. Vanhoutte,et al. Augmented Endothelium-Derived Hyperpolarizing Factor-Mediated Relaxations Attenuate Endothelial Dysfunction in Femoral and Mesenteric, but Not in Carotid Arteries from Type I Diabetic Rats , 2006, Journal of Pharmacology and Experimental Therapeutics.
[201] M. Giembycz,et al. Prostanoid receptor antagonists: development strategies and therapeutic applications , 2009, British journal of pharmacology.
[202] Y. Li,et al. Shear stress, SIRT1, and vascular homeostasis , 2010, Proceedings of the National Academy of Sciences.
[203] B. Fisslthaler,et al. The Na‐K‐ATPase is a target for an EDHF displaying characteristics similar to potassium ions in the porcine renal interlobar artery , 2002, British journal of pharmacology.
[204] C. Hill,et al. Structure, Function, and Endothelium-Derived Hyperpolarizing Factor in the Caudal Artery of the SHR and WKY Rat , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[205] G. Lavielle,et al. S 18886, a new thromboxane (TP)-receptor antagonist is the active isomer of S 18204 in all species, except in the guinea-pig. , 1997, Advances in experimental medicine and biology.
[206] A. Koller,et al. Enhanced release of prostaglandins contributes to flow-induced arteriolar dilation in eNOS knockout mice. , 1999, Circulation research.
[207] T. Murai,et al. Levcromakalim causes indirect endothelial hyperpolarization via a myo‐endothelial pathway , 1999, British journal of pharmacology.
[208] G. FitzGerald,et al. The isoprostanes in biology and medicine , 2001, Trends in Endocrinology & Metabolism.
[209] Yasuhiro Watanabe,et al. The involvement of reactive oxygen species and arachidonic acid in α1‐adrenoceptor‐induced smooth muscle cell proliferation and migration , 1997, British journal of pharmacology.
[210] D. Meeking,et al. Effects of cyclo-oxygenase inhibition on vasodilatory response to acetylcholine in patients with type 1 diabetes and nondiabetic subjects. , 2000, Diabetes care.
[211] S. Snyder,et al. Targeted disruption of the neuronal nitric oxide synthase gene , 1993, Cell.
[212] M. Kilberg,et al. Ontogeny of cationic amino acid transport systems in rat placenta. , 1994, The American journal of physiology.
[213] J. van de Voorde,et al. Influence of cytochrome P-450 inhibitors on endothelium-dependent nitro-L-arginine-resistant relaxation and cromakalim-induced relaxation in rat mesenteric arteries. , 1997, Journal of cardiovascular pharmacology.
[214] W. Campbell,et al. Role of endothelium-derived metabolites of arachidonic acid in enhanced pulmonary artery contractions in female rabbits. , 1996, Hypertension.
[215] Yanyan Zhao,et al. Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic acid production and arterial blood pressure. , 2009, Kidney international.
[216] J. Vane,et al. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation , 1976, Nature.
[217] Salam H. Ibrahim,et al. Dominant Negative Actions of Human Prostacyclin Receptor Variant Through Dimerization: Implications for Cardiovascular Disease , 2010, Arteriosclerosis, thrombosis, and vascular biology.
[218] B. Nilius,et al. Calcium‐activated chloride channels in bovine pulmonary artery endothelial cells. , 1997, The Journal of physiology.
[219] H. Suzuki,et al. Direct and indirect actions of acetylcholine and histamine on intrapulmonary artery and vein muscles of the rat. , 1989, The Japanese journal of physiology.
[220] K. Ley,et al. Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. , 1999, Science.
[221] T. Bolton,et al. Function of Interstitial Cells of Cajal in the Rabbit Portal Vein , 2004, Circulation research.
[222] T. Sakai. Acetylcholine induces Ca-dependent K currents in rabbit endothelial cells. , 1990, Japanese journal of pharmacology.
[223] P. Vanhoutte,et al. Endothelium‐dependent contractions in SHR: a tale of prostanoid TP and IP receptors , 2009, British journal of pharmacology.
[224] M. Yen,et al. Abnormal activation of K+ channels in aortic smooth muscle of rats with endotoxic shock: electrophysiological and functional evidence , 2000, British journal of pharmacology.
[225] K. Sugamura,et al. Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2 , 2001, The Journal of experimental medicine.
[226] L. Petrocellis,et al. The endocannabinoid system: a general view and latest additions , 2004, British journal of pharmacology.
[227] H. Nisell,et al. Diverse Mechanisms of Endothelium-Derived Hyperpolarizing Factor-Mediated Dilatation in Small Myometrial Arteries in Normal Human Pregnancy and Preeclampsia1 , 2010, Biology of reproduction.
[228] J. Fauchère,et al. Food intake regulation in rodents: Y5 or Y1 NPY receptors or both? , 2000, Canadian journal of physiology and pharmacology.
[229] J. Schwartz,et al. Formation and inactivation of endogenous cannabinoid anandamide in central neurons , 1994, Nature.
[230] P. Vanhoutte,et al. Hyperpolarization as a mechanism for endothelium‐dependent relaxations in the porcine coronary artery. , 1992, The Journal of physiology.
[231] K. C. Chang,et al. Possible superoxide radical-induced alteration of vascular reactivity in aortas from streptozotocin-treated rats. , 1993, The Journal of pharmacology and experimental therapeutics.
[232] R. Khalil,et al. Gender, sex hormones, and vascular tone. , 2004, American journal of physiology. Regulatory, integrative and comparative physiology.
[233] J. Zicha,et al. Regression of L-NAME–Induced Hypertension: The Role of Nitric Oxide and Endothelium-Derived Constricting Factor , 2008, Hypertension Research.
[234] W. Graier,et al. 11,12-Epoxyeicosatrienoic acid stimulates tyrosine kinase activity in porcine aortic endothelial cells. , 1998, European journal of pharmacology.
[235] J. Drijfhout,et al. Cross-presentation by intercellular peptide transfer through gap junctions , 2005, Nature.
[236] Maristela L Onozato,et al. Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems. , 2007, American journal of physiology. Heart and circulatory physiology.
[237] M. Majesky. Developmental basis of vascular smooth muscle diversity. , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[238] E. Canet,et al. Inhibitors of the cytochrome P450‐mono‐oxygenase and endothelium‐dependent hyperpolarizations in the guinea‐pig isolated carotid artery , 1996, British journal of pharmacology.
[239] G. Gardos,et al. The function of calcium in the potassium permeability of human erythrocytes. , 1958, Biochimica et biophysica acta.
[240] K. Goto,et al. Characterization of endothelium-dependent relaxation independent of NO and prostaglandins in guinea pig coronary artery. , 1998, The Journal of pharmacology and experimental therapeutics.
[241] F. Coceani,et al. Carbon monoxide‐induced relaxation of the ductus arteriosus in the lamb: evidence against the prime role of guanylyl cyclase , 1996, British journal of pharmacology.
[242] W. Vetter,et al. Obesity increases prostanoid-mediated vasoconstriction and vascular thromboxane receptor gene expression , 2002, Journal of hypertension.
[243] M. Oriowo,et al. Histamine-induced vasodilatation in the perfused mesenteric arterial bed of diabetic rats. , 2002, Vascular pharmacology.
[244] R. Gerzer,et al. NO-independent regulatory site on soluble guanylate cyclase , 2001, Nature.
[245] C. Lowenstein,et al. Increased Endothelial Exocytosis and Generation of Endothelin-1 Contributes to Constriction of Aged Arteries , 2010, Circulation research.
[246] P. Vallance,et al. An Endothelium-Derived Hyperpolarizing Factor–Like Factor Moderates Myogenic Constriction of Mesenteric Resistance Arteries in the Absence of Endothelial Nitric Oxide Synthase–Derived Nitric Oxide , 2001, Hypertension.
[247] S. Takai,et al. Tissue angiotensin II generating system by angiotensin-converting enzyme and chymase. , 2006, Journal of pharmacological sciences.
[248] M. Quon,et al. Endothelial dysfunction in mice with streptozotocin-induced type 1 diabetes is opposed by compensatory overexpression of cyclooxygenase-2 in the vasculature. , 2009, Endocrinology.
[249] M. Taggart,et al. Regulation of Endothelial-Dependent Relaxation in Human Systemic Arteries by SKCa and IKCa Channels , 2007, Reproductive Sciences.
[250] T. Hintze,et al. Amlodipine releases nitric oxide from canine coronary microvessels: an unexpected mechanism of action of a calcium channel-blocking agent. , 1998, Circulation.
[251] N. Kanaya,et al. Role of Endothelium-derived Hyperpolarizing Factor in Phenylephrine-induced Oscillatory Vasomotion in Rat Small Mesenteric Artery , 2003, Anesthesiology.
[252] R. Roman,et al. P-450 metabolites of arachidonic acid in the control of cardiovascular function. , 2002, Physiological reviews.
[253] S. Taddei,et al. Endothelium-dependent contractions to endothelin in the rat aorta are mediated by thromboxane A2. , 1993, Journal of cardiovascular pharmacology.
[254] T. Itoh,et al. K(+) channel blockers and cytochrome P450 inhibitors on acetylcholine-induced, endothelium-dependent relaxation in rabbit mesenteric artery. , 1999, European journal of pharmacology.
[255] M. Mulvany,et al. Nitric oxide, prostanoid and non‐NO, non‐prostanoid involvement in acetylcholine relaxation of isolated human small arteries , 2000, British journal of pharmacology.
[256] G. G. Emerson,et al. Endothelial cell pathway for conduction of hyperpolarization and vasodilation along hamster feed artery. , 2000, Circulation research.
[257] K. Porter,et al. Modulation of Ca(2+) signalling in human vascular endothelial cells by hydrogen sulfide. , 2010, Atherosclerosis.
[258] P Kouklis,et al. Ca(2+) signalling and PKCalpha activate increased endothelial permeability by disassembly of VE-cadherin junctions. , 2001, The Journal of physiology.
[259] V. Dzau. Significance of the vascular renin-angiotensin pathway. , 1986, Hypertension.
[260] P. Sorgen,et al. Gap Junction Protein Cx37 Interacts With Endothelial Nitric Oxide Synthase in Endothelial Cells , 2010, Arteriosclerosis, thrombosis, and vascular biology.
[261] H. Maeda,et al. Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization. , 2003, The Journal of clinical investigation.
[262] S. Okuyama,et al. Beneficial Effects of a New 20-Hydroxyeicosatetraenoic Acid Synthesis Inhibitor, TS-011 [N-(3-Chloro-4-morpholin-4-yl) Phenyl-N′-hydroxyimido Formamide], on Hemorrhagic and Ischemic Stroke , 2005, Journal of Pharmacology and Experimental Therapeutics.
[263] J. García-Sancho,et al. High affinity inhibition of Ca(2+)-dependent K+ channels by cytochrome P-450 inhibitors. , 1992, The Journal of biological chemistry.
[264] D. Gutterman,et al. Acetylcholine‐induced arteriolar dilation is reduced in streptozotocin‐induced diabetic rats with motor nerve dysfunction , 1999, British journal of pharmacology.
[265] R. Olcese,et al. The RCK2 domain of the human BKCa channel is a calcium sensor , 2008, Proceedings of the National Academy of Sciences.
[266] G. Fink,et al. Cyclooxygenase, p38 Mitogen-Activated Protein Kinase (MAPK), Extracellular Signal-Regulated Kinase MAPK, Rho Kinase, and Src Mediate Hydrogen Peroxide-Induced Contraction of Rat Thoracic Aorta and Vena Cava , 2007, Journal of Pharmacology and Experimental Therapeutics.
[267] S. Dryer,et al. Evidence for two-pore domain potassium channels in rat cerebral arteries. , 2006, American journal of physiology. Heart and circulatory physiology.
[268] J. Wood,et al. Local formation of angiotensin II in the rat aorta: effect of endothelium , 1990, British journal of pharmacology.
[269] R. Hammer,et al. Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development. , 2000, The Journal of clinical investigation.
[270] K. Kamata,et al. Cilostazol improves endothelial dysfunction by increasing endothelium-derived hyperpolarizing factor response in mesenteric arteries from Type 2 diabetic rats. , 2008, European journal of pharmacology.
[271] M. Hamann,et al. Human ClCa1 modulates anionic conduction of calcium-dependent chloride currents , 2009, The Journal of physiology.
[272] Y. Ouchi,et al. Elevated blood pressure and craniofaclal abnormalities in mice deficient in endothelin-1 , 1994, Nature.
[273] T. Itoh,et al. Reduced function of endothelial prostacyclin in human omental resistance arteries in pre‐eclampsia , 2002, The Journal of physiology.
[274] G. Burnstock. Purinergic Signaling and Vascular Cell Proliferation and Death , 2002, Arteriosclerosis, thrombosis, and vascular biology.
[275] S. P. Williams,et al. Role of prostaglandins in acetylcholine-induced contraction of aorta from spontaneously hypertensive and Wistar-Kyoto rats. , 1996, Hypertension.
[276] C. Mallari,et al. Role of endogenous nitric oxide in progression of atherosclerosis in apolipoprotein E-deficient mice. , 2000, American journal of physiology. Heart and circulatory physiology.
[277] E. Arikawa,et al. Effects of endothelin receptor blockade on hypervasoreactivity in streptozotocin-diabetic rats: vessel-specific involvement of thromboxane A2. , 2006, Canadian journal of physiology and pharmacology.
[278] H. Miura,et al. Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition. , 2006, American journal of physiology. Heart and circulatory physiology.
[279] D. Strøbæk,et al. Activation of the human, intermediate-conductance, Ca2+-activated K+ channel by methylxanthines , 2000, Pflügers Archiv.
[280] L. Ghiadoni,et al. Vasoconstriction to endogenous endothelin-1 is increased in the peripheral circulation of patients with essential hypertension. , 1999, Circulation.
[281] B. Lévy,et al. Plasticity of Human Adipose Lineage Cells Toward Endothelial Cells: Physiological and Therapeutic Perspectives , 2004, Circulation.
[282] K. Kamata,et al. Metformin normalizes endothelial function by suppressing vasoconstrictor prostanoids in mesenteric arteries from OLETF rats, a model of type 2 diabetes. , 2008, American journal of physiology. Heart and circulatory physiology.
[283] D. Pollock. CHRONIC STUDIES ON THE INTERACTION BETWEEN NITRIC OXIDE AND ENDOTHELIN IN CARDIOVASCULAR AND RENAL FUNCTION , 1999, Clinical and experimental pharmacology & physiology.
[284] B. Kwak,et al. Connexins in vascular physiology and pathology. , 2009, Antioxidants & redox signaling.
[285] T. Münzel,et al. Nebivolol: the somewhat-different beta-adrenergic receptor blocker. , 2009, Journal of the American College of Cardiology.
[286] Ying Yu,et al. A novel genetic model of selective COX-2 inhibition: comparison with COX-2 null mice. , 2007, Prostaglandins & other lipid mediators.
[287] D. Rodríguez‐Puyol,et al. The role of hydrogen peroxide in the contractile response to angiotensin II. , 2001, Molecular pharmacology.
[288] F. Cosentino,et al. Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries. , 1995, Circulation.
[289] K. Chandy,et al. Calmodulin Mediates Calcium-dependent Activation of the Intermediate Conductance KCa Channel,IKCa1 * , 1999, The Journal of Biological Chemistry.
[290] G. FitzGerald,et al. COX-2 inhibitors and cardiovascular risk. , 2007, Journal of cardiovascular pharmacology.
[291] W. Fleming. The electrogenic Na+, K+-pump in smooth muscle: physiologic and pharmacologic significance. , 1980, Annual review of pharmacology and toxicology.
[292] T. Lüscher,et al. Vascular Protective Effects of Angiotensin Converting Enzyme Inhibitors and their Relation to Clinical Events , 2001, Journal of cardiovascular pharmacology.
[293] S. Dhein. Gap junction channels in the cardiovascular system: pharmacological and physiological modulation. , 1998, Trends in pharmacological sciences.
[294] W. Campbell,et al. Acetylcholine-induced relaxation and hyperpolarization in small bovine adrenal cortical arteries: role of cytochrome P450 metabolites. , 2004, Endocrinology.
[295] C. Estrada,et al. Neuronal Nitric Oxide Synthase Activation by Vasoactive Intestinal Peptide in Bovine Cerebral Arteries , 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[296] T. Cocks,et al. Endothelium-dependent hyperpolarization as a remote anti-atherogenic mechanism. , 2002, Trends in pharmacological sciences.
[297] J. Zweier,et al. Hydrogen peroxide induces intracellular calcium oscillations in human aortic endothelial cells. , 1998, Circulation.
[298] C. Aalkjær,et al. Hypothesis for the Initiation of Vasomotion , 2001, Circulation research.
[299] R. Furchgott,et al. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine , 1980, Nature.
[300] A. Cameron,et al. Endothelial function is preserved in pregnant women with well‐controlled type 1 diabetes , 2002, BJOG : an international journal of obstetrics and gynaecology.
[301] S. Earley,et al. Ca2+ release from the sarcoplasmic reticulum is required for sustained TRPM4 activity in cerebral artery smooth muscle cells. , 2010, American journal of physiology. Cell physiology.
[302] A. Blann. How a Damaged Blood Vessel Wall Contibutes to Thrombosis and Hypertenasion , 2003, Pathophysiology of Haemostasis and Thrombosis.
[303] S. Sandow,et al. Spatial separation of endothelial small‐ and intermediate‐conductance calcium‐activated potassium channels (KCa) and connexins: possible relationship to vasodilator function? , 2006, Journal of anatomy.
[304] J. Falck,et al. Mechanism and signal transduction of 14 (R), 15 (S)-epoxyeicosatrienoic acid (14,15-EET) binding in guinea pig monocytes. , 2000, Prostaglandins & other lipid mediators.
[305] J. Hibbs,et al. Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite. , 1987, Science.
[306] Qingbo Xu,et al. Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice. , 2004, The Journal of clinical investigation.
[307] H. Shimokawa,et al. Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice , 2008, The Journal of experimental medicine.
[308] D. Kohan,et al. Regulation of blood pressure and salt homeostasis by endothelin. , 2011, Physiological reviews.
[309] M. Gladwin,et al. The functional nitrite reductase activity of the heme-globins. , 2008, Blood.
[310] Donald G Welsh,et al. WHAT'S WHERE AND WHY AT A VASCULAR MYOENDOTHELIAL MICRODOMAIN SIGNALLING COMPLEX , 2009, Clinical and experimental pharmacology & physiology.
[311] R. Busse,et al. Epoxyeicosatrienoic Acids Regulate Trp Channel–Dependent Ca2+ Signaling and Hyperpolarization in Endothelial Cells , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[312] C. Hillard. Endocannabinoids and vascular function. , 2000, The Journal of pharmacology and experimental therapeutics.
[313] V. Richard,et al. Arterial Stiffness Is Regulated by Nitric Oxide and Endothelium-Derived Hyperpolarizing Factor During Changes in Blood Flow in Humans , 2010, Hypertension.
[314] M. Félétou,et al. Aging and prostacyclin responses in aorta and platelets from WKY and SHR rats. , 2008, American journal of physiology. Heart and circulatory physiology.
[315] H. Dvorak,et al. Neutrophils Emigrate from Venules by a Transendothelial Cell Pathway in Response to FMLP , 1998, The Journal of experimental medicine.
[316] Hiroaki Shimokawa,et al. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries. , 2002, Biochemical and biophysical research communications.
[317] N. Standen,et al. ATP-sensitive and inwardly rectifying potassium channels in smooth muscle. , 1997, Physiological reviews.
[318] K. Pritchard,et al. Mechanisms of activation of eNOS by 20-HETE and VEGF in bovine pulmonary artery endothelial cells. , 2006, American journal of physiology. Lung cellular and molecular physiology.
[319] T. Griffith. Endothelium‐dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis? , 2004, British journal of pharmacology.
[320] T. Tanabe,et al. Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence , 1988, FEBS letters.
[321] V. Marzo,et al. Endocannabinoids and the control of energy balance , 2007, Trends in Endocrinology & Metabolism.
[322] A. Ahluwalia,et al. Vanilloid Receptor TRPV1, Sensory C-Fibers, and Vascular Autoregulation: A Novel Mechanism Involved in Myogenic Constriction , 2004, Circulation research.
[323] N. Abraham,et al. Endothelial Dysfunction and Hypertension in Rats Transduced With CYP4A2 Adenovirus , 2006, Circulation research.
[324] L. Toro,et al. MaxiK channel-mediated relaxation of guinea-pig aorta following stimulation of IP receptor with beraprost via cyclic AMP-dependent and -independent mechanisms , 2001, Naunyn-Schmiedeberg's Archives of Pharmacology.
[325] D. Krause,et al. Male-female differences in the relative contribution of endothelial vasodilators released by rat tail artery. , 2002, Life sciences.
[326] J. Patlak,et al. Functional Coupling of Ryanodine Receptors to KCa Channels in Smooth Muscle Cells from Rat Cerebral Arteries , 1999, The Journal of general physiology.
[327] W. Campbell,et al. Regulation of potassium channels in coronary arterial smooth muscle by endothelium-derived vasodilators. , 1997, Hypertension.
[328] P. Vanhoutte,et al. Further investigation of endothelium‐derived hyperpolarizing factor (EDHF) in rat hepatic artery: studies using 1‐EBIO and ouabain , 1999, British journal of pharmacology.
[329] R. Berne. The role of adenosine in the regulation of coronary blood flow. , 1980, Circulation research.
[330] B. Lévy,et al. Cyclooxygenase Involvement in Thromboxane-Dependent Contraction in Rat Mesenteric Resistance Arteries , 2004, Hypertension.
[331] M. Maclean,et al. Pulmonary hypertension secondary to left ventricular dysfunction: the role of nitric oxide and endothelin‐1 in the control of pulmonary vascular tone , 2002, British journal of pharmacology.
[332] P. Vanhoutte,et al. Is endothelin involved in the pathogenesis of hypertension? , 1993, Hypertension.
[333] A. A. Taylor,et al. Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries. , 1993, The Journal of clinical investigation.
[334] A. Nicolosi,et al. Mitochondrial Sources of H2O2 Generation Play a Key Role in Flow-Mediated Dilation in Human Coronary Resistance Arteries , 2003, Circulation research.
[335] Jian-Kang Chen,et al. Transfection of an Active Cytochrome P450 Arachidonic Acid Epoxygenase Indicates That 14,15-Epoxyeicosatrienoic Acid Functions as an Intracellular Second Messenger in Response to Epidermal Growth Factor* , 1999, The Journal of Biological Chemistry.
[336] M. Nelson,et al. TRPV4 Forms a Novel Ca2+ Signaling Complex With Ryanodine Receptors and BKCa Channels , 2005, Circulation research.
[337] T. Sundqvist. Bovine aortic endothelial cells release hydrogen peroxide , 1991, Journal of cellular physiology.
[338] W. Graier,et al. Activation of microsomal cytochrome P450 mono‐oxygenase by Ca2+ store depletion and its contribution to Ca2+ entry in porcine aortic endothelial cells , 1997, British journal of pharmacology.
[339] P. Ganz,et al. Role of Endothelin-1 in the Active Constriction of Human Atherosclerotic Coronary Arteries , 2001, Circulation.
[340] N. Gokina,et al. Augmented EDHF signaling in rat uteroplacental vasculature during late pregnancy. , 2010, American journal of physiology. Heart and circulatory physiology.
[341] L. Salkoff,et al. Transplantable sites confer calcium sensitivity to BK channels , 1999, Nature Neuroscience.
[342] R. Brandes,et al. N(G)-nitro-L-arginine- and indomethacin-resistant endothelium-dependent relaxation in the rabbit renal artery: effect of hypercholesterolemia. , 1997, Atherosclerosis.
[343] J. Falck,et al. Role of SKCa and IKCa in endothelium‐dependent hyperpolarizations of the guinea‐pig isolated carotid artery , 2005, British journal of pharmacology.
[344] M. Amrani,et al. Role of endogenous endothelin in the regulation of basal coronary tone in the rat , 1998, The Journal of physiology.
[345] A 4-AP-sensitive current is enhanced by chronic carbon monoxide exposure in coronary artery myocytes. , 2002, American journal of physiology. Heart and circulatory physiology.
[346] K. Kamata,et al. Specific impairment of endothelium-derived hyperpolarizing factor-type relaxation in mesenteric arteries from streptozotocin-induced diabetic mice. , 2006, Vascular pharmacology.
[347] J. Stallone,et al. Sexual dimorphism in prostanoid-potentiated vascular contraction: roles of endothelium and ovarian steroids. , 2002, American journal of physiology. Heart and circulatory physiology.
[348] R. Motterlini. Carbon monoxide-releasing molecules (CO-RMs): vasodilatory, anti-ischaemic and anti-inflammatory activities. , 2007, Biochemical Society transactions.
[349] C. Triggle,et al. Reduced EDHF responses and connexin activity in mesenteric arteries from the insulin-resistant obese Zucker rat , 2008, Diabetologia.
[350] S. Narumiya,et al. Thromboxane A2 Regulates Vascular Tone via Its Inhibitory Effect on the Expression of Inducible Nitric Oxide Synthase , 2003, Circulation.
[351] R. Wang,et al. Resurgence of carbon monoxide: an endogenous gaseous vasorelaxing factor. , 1998, Canadian journal of physiology and pharmacology.
[352] C. Yost. Update on tandem pore (2P) domain K+ channels. , 2003, Current Drug Targets.
[353] D. Lidington,et al. Deletion of neuronal NOS prevents impaired vasodilation in septic mouse skeletal muscle. , 2007, Cardiovascular research.
[354] D. Krause,et al. 17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation. , 2003, American journal of physiology. Heart and circulatory physiology.
[355] Y. Minamiya,et al. Ca2+ waves in lung capillary endothelium. , 1996, Circulation research.
[356] A. Gerbes,et al. Purine metabolism in cultured coronary endothelial cells. , 1979, Advances in experimental medicine and biology.
[357] T. Ishii,et al. Mechanism of calcium gating in small-conductance calcium-activated potassium channels , 1998, Nature.
[358] E. Canet,et al. Endothelium‐derived factors and hyperpolarization of the carotid artery of the guinea‐pig , 1996, British journal of pharmacology.
[359] R. Busse,et al. New fACEs to the renin-angiotensin system. , 2005, Physiology.
[360] C. Delaey,et al. Retinal arterial tone is controlled by a retinal-derived relaxing factor. , 1998, Circulation research.
[361] V. Miller,et al. Sex steroids and endothelial function: translating basic science to clinical practice. , 2007, Trends in pharmacological sciences.
[362] F. Ruiz-Marcos,et al. Mechanisms of the increased pressor response to vasopressors in the mesenteric bed of nitric oxide-deficient hypertensive rats. , 2001, European journal of pharmacology.
[363] M. Kunitomo,et al. Altered endothelium-dependent responsiveness in the aortas and renal arteries of Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of non-insulin-dependent diabetes mellitus. , 2000, General pharmacology.
[364] M. Cipolla,et al. SKCa and IKCa Channels, Myogenic Tone, and Vasodilator Responses in Middle Cerebral Arteries and Parenchymal Arterioles: Effect of Ischemia and Reperfusion , 2009, Stroke.
[365] B. Duling,et al. Integrated Ca2+ Signaling Between Smooth Muscle and Endothelium of Resistance Vessels , 2000, Circulation research.
[366] D. Fulton,et al. Subcellular targeting and trafficking of nitric oxide synthases. , 2006, The Biochemical journal.
[367] J. Adelman,et al. Determinants contributing to estrogen-regulated expression of SK3. , 2003, Biochemical and biophysical research communications.
[368] M. Murakami,et al. Prostaglandin E synthases: Understanding their pathophysiological roles through mouse genetic models. , 2010, Biochimie.
[369] T. Hla,et al. Regulation of vascular physiology and pathology by the S1P2 receptor subtype. , 2008, Cardiovascular research.
[370] M. Randall,et al. Sex differences in the relative contributions of nitric oxide and EDHF to agonist‐stimulated endothelium‐dependent relaxations in the rat isolated mesenteric arterial bed , 1998, British journal of pharmacology.
[371] A. Quyyumi,et al. Aspirin improves endothelial dysfunction in atherosclerosis. , 1998, Circulation.
[372] M. Walsh,et al. Delayed Rectifier K + Channels of Vascular Smooth Muscle: Characterization, Function, and Regulation by Phosphorylation , 2001 .
[373] C. de Wit,et al. Signaling across Myoendothelial Gap Junctions—Fact or fiction? , 2008, Cell communication & adhesion.
[374] A. Ahluwalia,et al. Endothelium-derived C-type natriuretic peptide: more than just a hyperpolarizing factor. , 2005, Trends in pharmacological sciences.
[375] L. Ghiadoni,et al. Vasodilation to bradykinin is mediated by an ouabain-sensitive pathway as a compensatory mechanism for impaired nitric oxide availability in essential hypertensive patients. , 1999, Circulation.
[376] Yuan-sheng Gao,et al. Nebivolol Induces Endothelium Dependent Relaxatíons of Canine Coronary Arteries , 1991, Journal of cardiovascular pharmacology.
[377] G. FitzGerald,et al. Prostaglandin F2α elevates blood pressure and promotes atherosclerosis , 2009, Proceedings of the National Academy of Sciences.
[378] S. Suissa,et al. Use of First- and Second-Generation Cyclooxygenase-2–Selective Nonsteroidal Antiinflammatory Drugs and Risk of Acute Myocardial Infarction , 2006, Circulation.
[379] B. Nilius,et al. Diversity of TRP channel activation. , 2004, Novartis Foundation symposium.
[380] G Kaley,et al. Role of shear stress and endothelial prostaglandins in flow- and viscosity-induced dilation of arterioles in vitro. , 1993, Circulation research.
[381] J. V. Levy. Prostacyclin-induced contraction of isolated aortic strips from normal and spontaneously hypertensive rats (SHR). , 1980, Prostaglandins.
[382] B. Fredholm,et al. Pharmacology of adenosine A2A receptors. , 1996, Trends in pharmacological sciences.
[383] T. Grosser,et al. PROSTANOIDS IN HEALTH AND DISEASE , 1979 .
[384] A. Branzi,et al. The endothelin system in pulmonary arterial hypertension. , 2004, Cardiovascular research.
[385] W. Giles,et al. Natriuretic peptide C receptor signalling in the heart and vasculature , 2008, The Journal of physiology.
[386] G. Bessard,et al. Effect of 5-lipoxygenase blockade on blood pressure and acetylcholine-evoked endothelium-dependent contraction in aorta from spontaneously hypertensive rats , 2006, Journal of hypertension.
[387] B. Isakson,et al. Biological and biophysical properties of vascular connexin channels. , 2009, International review of cell and molecular biology.
[388] L. Liotta,et al. Basement membrane collagen: degradation by migrating endothelial cells. , 1983, Science.
[389] S. Fitzgerald,et al. Endothelial dysfunction and arterial pressure regulation during early diabetes in mice: roles for nitric oxide and endothelium-derived hyperpolarizing factor. , 2007, American journal of physiology. Regulatory, integrative and comparative physiology.
[390] S. Narumiya,et al. Increased Bleeding Tendency and Decreased Susceptibility to Thromboembolism in Mice Lacking the Prostaglandin E Receptor Subtype EP3 , 2001, Circulation.
[391] C. Matouk,et al. Epigenetic Regulation of Vascular Endothelial Gene Expression , 2008, Circulation research.
[392] M. Gladwin,et al. Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation , 2003, Nature Medicine.
[393] P. Cuevas,et al. Diabetes impairs endothelium-dependent relaxation of human penile vascular tissues mediated by NO and EDHF. , 2003, Biochemical and biophysical research communications.
[394] J. Beavo,et al. Regulation of Nitric Oxide–Sensitive Guanylyl Cyclase Cyclic GMP Phosphodiesterases and Regulation of Smooth Muscle Function Structure, Regulation, and Function of Membrane Guanylyl Cyclase Receptors, With a Focus on GC-A Cyclic GMP–Dependent Protein Kinases and the Cardiovascular System: Insights F , 2003 .
[395] W. Graier,et al. Mechanisms of L‐NG nitroarginine/indomethacin‐resistant relaxation in bovine and porcine coronary arteries , 1996, British journal of pharmacology.
[396] S. Snyder,et al. Nitric oxide: a physiologic messenger molecule. , 1994, Annual review of biochemistry.
[397] M. Nishiyama,et al. Potassium channels activated in the endothelium‐dependent hyperpolarization in guinea‐pig coronary artery , 1998, The Journal of physiology.
[398] M. Kennedy,et al. A common precursor for hematopoietic and endothelial cells. , 1998, Development.
[399] F. Luft,et al. Hydrogen peroxide, potassium currents, and membrane potential in human endothelial cells. , 1999, Circulation.
[400] D. Woodward,et al. Identification of a prostanoid FP receptor population producing endothelium‐dependent vasorelaxation in the rabbit jugular vein , 1995, British journal of pharmacology.
[401] C. Aalkjaer,et al. Studies of the renin-angiotensin system in the wall of rat femoral resistance vessels. , 1991, European journal of pharmacology.
[402] A. Yim,et al. Histidine-tryptophan-ketoglutarate solution maximally preserves endothelium-derived hyperpolarizing factor-mediated function during heart preservation: comparison with University of Wisconsin solution. , 2004, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
[403] N. Toda,et al. The Pharmacology of Nitric Oxide in the Peripheral Nervous System of Blood Vessels , 2003, Pharmacological Reviews.
[404] P. Mannon,et al. Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2. , 1998, The Journal of clinical investigation.
[405] P. Vanhoutte,et al. Role of potassium in regulating blood flow and blood pressure. , 2006, American journal of physiology. Regulatory, integrative and comparative physiology.
[406] M. T. Roberts,et al. Modulation of recombinant small-conductance Ca(2+)-activated K(+) channels by the muscle relaxant chlorzoxazone and structurally related compounds. , 2001, The Journal of pharmacology and experimental therapeutics.
[407] P. Taylor,et al. The effect of hyperglycaemia on function of rat isolated mesenteric resistance artery , 1994, British journal of pharmacology.
[408] Ageing suppresses endothelium‐dependent relaxation and generates contraction mediated by the muscarinic receptors in vascular smooth muscle of normotensive Wistar‐Kyoto and spontaneously hypertensive rats , 1988, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.
[409] S. Bunting,et al. Vascular endothelial growth factor-mediated endothelium-dependent relaxation is blunted in spontaneously hypertensive rats. , 2001, The Journal of pharmacology and experimental therapeutics.
[410] J. Adelman,et al. Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin , 2001, Nature.
[411] K. Kamata,et al. Imbalance between endothelium-derived relaxing and contracting factors in mesenteric arteries from aged OLETF rats, a model of Type 2 diabetes. , 2007, American journal of physiology. Heart and circulatory physiology.
[412] F. Recchia,et al. Acute and Chronic Endothelial Dysfunction: Implications for the Development of Heart Failure , 2004, Heart Failure Reviews.
[413] R. Busse,et al. The tissue renin–angiotensin system and intracellular signalling , 2006, Current opinion in nephrology and hypertension.
[414] M. Omata,et al. Effects of hypertension, diabetes mellitus, and hypercholesterolemia on endothelin type B receptor-mediated nitric oxide release from rat kidney. , 1999, Circulation.
[415] J. Vane,et al. Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin. , 1978, Pharmacological reviews.
[416] T. Hla,et al. Human cyclooxygenase-2 cDNA. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[417] S. Verma,et al. Cellular basis of endothelial dysfunction in small mesenteric arteries from spontaneously diabetic (db/db−/−) mice: role of decreased tetrahydrobiopterin bioavailability , 2002, British journal of pharmacology.
[418] A. Kristof,et al. Attenuation of endothelium-dependent hyperpolarizing factor by bacterial lipopolysaccharides. , 1997, European journal of pharmacology.
[419] L. Muller,et al. Endothelin-converting Enzyme-1, Abundance of Isoforms a-d and Identification of a Novel Alternatively Spliced Variant Lacking a Transmembrane Domain* , 2005, Journal of Biological Chemistry.
[420] H. Itoh,et al. Cytokine-induced C-type natriuretic peptide (CNP) secretion from vascular endothelial cells--evidence for CNP as a novel autocrine/paracrine regulator from endothelial cells. , 1993, Endocrinology.
[421] D. Triggle. Cardiovascular T-type calcium channels: physiological and pharmacological significance. , 1997, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.
[422] C. Garland. Compromised vascular endothelial cell SKCa activity: a fundamental aspect of hypertension? , 2010, British journal of pharmacology.
[423] J. Yamazaki,et al. Chloride channels and their functional roles in smooth muscle tone in the vasculature. , 2001, Japanese journal of pharmacology.
[424] S. Moncada,et al. A specific inhibitor of nitric oxide formation from l‐arginine attenuates endothelium‐dependent relaxation , 1989, British journal of pharmacology.
[425] W. S. Lee,et al. Localization and quantification of endoplasmic reticulum Ca(2+)-ATPase isoform transcripts. , 1995, The American journal of physiology.
[426] M. Taggart,et al. TNF-α Alters Nitric Oxide- and Endothelium-Derived Hyperpolarizing Factor-Mediated Vasodilatation in Human Omental Arteries , 2008, Hypertension in pregnancy.
[427] J. A. Peters,et al. Transient receptor potential cation channels in disease. , 2007, Physiological reviews.
[428] C. Robertson,et al. Potentiated endothelium-derived hyperpolarizing factor-mediated dilations in cerebral arteries following mild head injury. , 2001, Journal of neurotrauma.
[429] C. Waters,et al. IP3 Constricts Cerebral Arteries via IP3 Receptor–Mediated TRPC3 Channel Activation and Independently of Sarcoplasmic Reticulum Ca2+ Release , 2008, Circulation research.
[430] P. Vanhoutte,et al. Hydrogen peroxide and endothelium-dependent hyperpolarization in the guinea-pig carotid artery. , 2005, European journal of pharmacology.
[431] H. Thai,et al. Angiotensin Subtype 1 Receptor (AT1) Blockade Improves Vasorelaxation in Heart Failure by Up-Regulation of Endothelial Nitric-Oxide Synthase via Activation of the AT2 Receptor , 2003, Journal of Pharmacology and Experimental Therapeutics.
[432] Yuan-sheng Gao,et al. Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting. , 2007, The Journal of clinical investigation.
[433] L. Ghiadoni,et al. Hypertension causes premature aging of endothelial function in humans. , 1997, Hypertension.
[434] J. Pollock,et al. Role of endothelin ET(A) receptors in the hypertension produced by 4-day L-nitroarginine methyl ester and cyclosporine treatment. , 1998, European journal of pharmacology.
[435] L. Ghiadoni,et al. Endogenous estrogen and acetylcholine-induced vasodilation in normotensive women. , 1997, Hypertension.
[436] A. Kitabatake,et al. Endothelium‐dependent hyperpolarization and relaxation in mesenteric arteries of middle‐aged rats: influence of oestrogen , 2002, British journal of pharmacology.
[437] S. Katz,et al. Impaired Acetlcholine‐Mediated Vasodilation in Patients With Congestive Heart Failure Role of Endothelium‐Derived Vasodilating and Vasoconstricting Factors , 1993, Circulation.
[438] D. Fulton,et al. Contribution of NO and cytochrome P450 to the vasodilator effect of bradykinin in the rat kidney , 1992, British journal of pharmacology.
[439] K. Chandy,et al. Blockade of the Intermediate-Conductance Calcium-Activated Potassium Channel as a New Therapeutic Strategy for Restenosis , 2003, Circulation.
[440] G. Godlewski,et al. Receptors for acylethanolamides-GPR55 and GPR119. , 2009, Prostaglandins & other lipid mediators.
[441] N. Flavahan. Balancing prostanoid activity in the human vascular system. , 2007, Trends in pharmacological sciences.
[442] S S Segal,et al. Flow control among microvessels coordinated by intercellular conduction. , 1986, Science.
[443] T. Poulos,et al. Crystal Structures of Zinc-free and -bound Heme Domain of Human Inducible Nitric-oxide Synthase , 1999, The Journal of Biological Chemistry.
[444] S. P. Marrelli,et al. Altered Endothelial Ca2+ Regulation After Ischemia/Reperfusion Produces Potentiated Endothelium-Derived Hyperpolarizing Factor–Mediated Dilations , 2002, Stroke.
[445] R. Busse,et al. Dynamic Modulation of Interendothelial Gap Junctional Communication by 11,12-Epoxyeicosatrienoic Acid , 2002, Circulation research.
[446] E. Canet,et al. Bradykinin and changes in microvascular permeability in the hamster cheek pouch: role of nitric oxide , 1996, British journal of pharmacology.
[447] Shenyuan L. Zhang,et al. The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers , 2008, Nature.
[448] A. Ahluwalia,et al. Vascular actions of natriuretic peptides , 2004, Basic Research in Cardiology.
[449] William A. Catterall,et al. International Union of Pharmacology. XL. Compendium of Voltage-Gated Ion Channels: Calcium Channels , 2003, Pharmacological Reviews.
[450] C. Garland,et al. K+ is an endothelium-derived hyperpolarizing factor in rat arteries , 1998, Nature.
[451] Tomoya Yamashita,et al. Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice. , 2002, The Journal of clinical investigation.
[452] P. Vanhoutte,et al. Endothelium‐dependent contractions to acetylcholine, ATP and the calcium ionophore A 23187 in aortas from spontaneously hypertensive and normotensive rats , 2004, Fundamental & clinical pharmacology.
[453] C. Bronner,et al. Angiotensin II-Induced Hypertension Is Associated with a Selective Inhibition of Endothelium-Derived Hyperpolarizing Factor-Mediated Responses in the Rat Mesenteric Artery , 2009, Journal of Pharmacology and Experimental Therapeutics.
[454] B. Nilius,et al. Ion channels and their functional role in vascular endothelium. , 2001, Physiological reviews.
[455] D. Behm,et al. Epoxyeicosatrienoic Acids Function as Selective, Endogenous Antagonists of Native Thromboxane Receptors: Identification of a Novel Mechanism of Vasodilation , 2009, Journal of Pharmacology and Experimental Therapeutics.
[456] G. Burnstock,et al. Increased flow‐induced ATP release from isolated vascular endothelial cells but not smooth muscle cells , 1991, British journal of pharmacology.
[457] R. Roman,et al. Reversal of delayed vasospasm by an inhibitor of the synthesis of 20-HETE. , 2005, American journal of physiology. Heart and circulatory physiology.
[458] S. Aslam,et al. Impaired Endothelial Function and Microvascular Asymmetrical Dimethylarginine in Angiotensin II–Infused Rats: Effects of Tempol , 2010, Hypertension.
[459] T. Lüscher,et al. Blood pressure and vascular effects of endothelin blockade in chronic nitric oxide-deficient hypertension. , 1997, Hypertension.
[460] G. FitzGerald,et al. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[461] O. Griffith,et al. NG-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo? , 1989, Biochemical and biophysical research communications.
[462] D. Andersson,et al. Involvement of sensory nerves in vasodilator responses to acetylcholine and potassium ions in rat hepatic artery , 2000, British journal of pharmacology.
[463] M. Wolin. Interactions of oxidants with vascular signaling systems. , 2000, Arteriosclerosis, thrombosis, and vascular biology.
[464] M. Freichel,et al. Impairment of Store-Operated Ca2+ Entry in TRPC4−/− Mice Interferes With Increase in Lung Microvascular Permeability , 2002, Circulation research.
[465] Y. Sasaguri,et al. Nephrogenic diabetes insipidus in mice lacking all nitric oxide synthase isoforms. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[466] A. Agarwal,et al. Heme oxygenase-1 and carbon monoxide in vascular pathobiology: focus on angiogenesis. , 2008, Circulation.
[467] Sadao Kimura,et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells , 1988, Nature.
[468] V. Winn,et al. cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[469] S. Barman. Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C. , 2007, American journal of physiology. Lung cellular and molecular physiology.
[470] R. Köhler,et al. Expression and Function of Endothelial Ca2+-Activated K+ Channels in Human Mesenteric Artery: A Single-Cell Reverse Transcriptase–Polymerase Chain Reaction and Electrophysiological Study In Situ , 2000, Circulation research.
[471] R. Busse,et al. A transferable, beta‐naphthoflavone‐inducible, hyperpolarizing factor is synthesized by native and cultured porcine coronary endothelial cells. , 1996, The Journal of physiology.
[472] O. Bertrand,et al. Influence of Postangioplasty β-Irradiation on Endothelial Function in Porcine Coronary Arteries , 2000 .
[473] P. Devillier,et al. Cysteinyl Leukotrienes Modulate Angiotensin II Constrictor Effects on Aortas From Streptozotocin-Induced Diabetic Rats , 2001, Arteriosclerosis, thrombosis, and vascular biology.
[474] B. Koller,et al. The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth , 1997, Nature.
[475] N. Weintraub,et al. Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation. , 1998, Circulation research.
[476] J. Falck,et al. A Role for Heterocellular Coupling and EETs in Dilation of Rat Cremaster Arteries , 2006, Microcirculation.
[477] M. Biel,et al. Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4−/− mice , 2001, Nature Cell Biology.
[478] W. Campbell,et al. Membrane Potential-Dependent Inhibition of Platelet Adhesion to Endothelial Cells by Epoxyeicosatrienoic Acids , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[479] M. Abeywardena,et al. Age- and Hypertension-induced Changes in Abnormal Contractions in Rat Aorta , 2002, Journal of cardiovascular pharmacology.
[480] R. Cohen,et al. Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits. , 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.
[481] F. Lenz,et al. ET-1- and NO-mediated signal transduction pathway in human brain capillary endothelial cells. , 2003, American journal of physiology. Cell physiology.
[482] Mark T. Nelson,et al. Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K(+) current in K(+)-mediated vasodilation. , 2000, Circulation research.
[483] G. Saade,et al. The role of endothelium-derived hyperpolarizing factor in the regulation of the uterine circulation in pregnant rats. , 2001, American journal of obstetrics and gynecology.
[484] J. Burnett,et al. Thrombin enhances the release of endothelin from cultured porcine aortic endothelial cells. , 1989, European journal of pharmacology.
[485] A. Malik,et al. TRP channels and the control of vascular function. , 2010, Current opinion in pharmacology.
[486] L. Poston,et al. The oestrogen receptor β contributes to sex related differences in endothelial function of murine small arteries via EDHF , 2006, The Journal of physiology.
[487] M. Saito,et al. Attenuation of nitric oxide- and prostaglandin-independent vasodilation of retinal arterioles induced by acetylcholine in streptozotocin-treated rats. , 2007, Vascular pharmacology.
[488] A. Maio,et al. Downregulation of connexin 43 gene expression in rat heart during inflammation. The role of tumour necrosis factor. , 1999, Cytokine.
[489] N. Holstein-Rathlou,et al. Is there a role for T-type Ca2+ channels in regulation of vasomotor tone in mesenteric arterioles? , 2009, Canadian journal of physiology and pharmacology.
[490] R. Weisbrod,et al. Mechanism of nitric oxide-induced vasodilatation: refilling of intracellular stores by sarcoplasmic reticulum Ca2+ ATPase and inhibition of store-operated Ca2+ influx. , 1999, Circulation research.
[491] K. Willecke,et al. Impaired conduction of vasodilation along arterioles in connexin40-deficient mice. , 2000, Circulation research.
[492] C. Davison,et al. Nitric oxide-dependent and -independent mechanisms account for gender differences in vasodilation to acetylcholine. , 2000, The Journal of pharmacology and experimental therapeutics.
[493] C. Thuillez,et al. Crucial Role of NO and Endothelium-Derived Hyperpolarizing Factor in Human Sustained Conduit Artery Flow-Mediated Dilatation , 2006, Hypertension.
[494] K. Desai,et al. Nitric oxide synthase inhibition exaggerates the hypotensive response to ghrelin: role of calcium-activated potassium channels , 2005, Journal of hypertension.
[495] P. Vanhoutte. Say NO to ET. , 2000, Journal of the autonomic nervous system.
[496] R. Sadja,et al. Gating of GIRK Channels Details of an Intricate, Membrane-Delimited Signaling Complex , 2003, Neuron.
[497] F. Gage,et al. Cell fusion-independent differentiation of neural stem cells to the endothelial lineage , 2004, Nature.
[498] P. Pacher,et al. Endocannabinoids and cannabinoid receptors in ischaemia–reperfusion injury and preconditioning , 2008, British journal of pharmacology.
[499] I. Nishio,et al. Arterial relaxation mediated by endothelium-derived hyperpolarizing factor in hypertension induced by chronic inhibition of nitric oxide synthesis. , 1999, Clinical and experimental hypertension.
[500] B. Nilius,et al. Transient receptor potential channels in endothelium: solving the calcium entry puzzle? , 2003, Endothelium : journal of endothelial cell research.
[501] K. Hultenby,et al. Endothelium-derived hyperpolarizing factor in preeclampsia: heterogeneous contribution, mechanisms, and morphological prerequisites. , 2008, American journal of physiology. Regulatory, integrative and comparative physiology.
[502] W. Campbell,et al. Hypercholesterolemia Enhances 15-Lipoxygenase–Mediated Vasorelaxation and Acetylcholine-Induced Hypotension , 2008, Arteriosclerosis, thrombosis, and vascular biology.
[503] A. Avogaro,et al. Characterization of endothelial progenitor cells. , 2005, Biochemical and biophysical research communications.
[504] P. Vanhoutte,et al. Role of endothelial cell hyperpolarization in EDHF‐mediated responses in the guinea‐pig carotid artery , 2000, British journal of pharmacology.
[505] S. Taddei,et al. Role of endothelium in endothelin-evoked contractions in the rat aorta. , 1993, Hypertension.
[506] P. Matheson,et al. Tempol, an antioxidant, restores endothelium-derived hyperpolarizing factor-mediated vasodilation during hypertension. , 2003, European journal of pharmacology.
[507] J. Maruyama,et al. Acetylcholine-induced endothelium-derived contracting factor in hypoxic pulmonary hypertensive rats. , 1999, Journal of applied physiology.
[508] L. Rosenfeld,et al. Ifetroban sodium: an effective TxA2/PGH2 receptor antagonist. , 2006, Cardiovascular drug reviews.
[509] T. Itoh,et al. Involvement of H2O2 in superoxide‐dismutase‐induced enhancement of endothelium‐dependent relaxation in rabbit mesenteric resistance artery , 2003, British journal of pharmacology.
[510] W. Bao,et al. Systemic Activation of the Transient Receptor Potential Vanilloid Subtype 4 Channel Causes Endothelial Failure and Circulatory Collapse: Part 2 , 2008, Journal of Pharmacology and Experimental Therapeutics.
[511] A. Ichikawa,et al. Uptake of histamine by mouse peritoneal macrophages and a macrophage cell line, RAW264.7. , 2003, American journal of physiology. Cell physiology.
[512] P. Ganz,et al. Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. , 1986, The New England journal of medicine.
[513] M. Focardi,et al. H2O2-induced redox-sensitive coronary vasodilation is mediated by 4-aminopyridine-sensitive K+ channels. , 2006, American journal of physiology. Heart and circulatory physiology.
[514] M. Fujishima,et al. Renin-Angiotensin System Blockade Improves Endothelial Dysfunction in Hypertension , 2000, Hypertension.
[515] A. Kawabata,et al. Direct inhibition of endothelial nitric oxide synthase by hydrogen sulfide: contribution to dual modulation of vascular tension. , 2007, Toxicology.
[516] Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[517] L. Janssen,et al. 8-isoprostaglandin E(2) activates Ca(2+)-dependent K(+) current via cyclic AMP signaling pathway in murine renal artery. , 2005, European journal of pharmacology.
[518] E. Vigmond,et al. KIR channels function as electrical amplifiers in rat vascular smooth muscle , 2008, The Journal of physiology.
[519] J. Falck,et al. Gender-specific compensation for the lack of NO in the mediation of flow-induced arteriolar dilation. , 2001, American journal of physiology. Heart and circulatory physiology.
[520] R. Schubert,et al. Iloprost activates KCa channels of vascular smooth muscle cells: role of cAMP-dependent protein kinase. , 1996, The American journal of physiology.
[521] R. Busse,et al. Display of the characteristics of endothelium‐derived hyperpolarizing factor by a cytochrome P450‐derived arachidonic acid metabolite in the coronary microcirculation , 1994, British journal of pharmacology.
[522] G. Lip,et al. Virchow’s Triad Revisited: Blood Constituents , 2003, Pathophysiology of Haemostasis and Thrombosis.
[523] Z. Fortes,et al. Influence of female sex hormones on endothelium-derived vasoconstrictor prostanoid generation in microvessels of spontaneously hypertensive rats. , 1999, Hypertension.
[524] W. Hodgson,et al. Potentiation by endothelin‐1 of 5‐hydroxytryptamine responses in aortae from streptozotocin‐diabetic rats: a role for thromboxane A2 , 1995, British journal of pharmacology.
[525] J. Kawabe,et al. Downregulation of nitric oxide accumulation by cyclooxygenase-2 induction and thromboxane A2 production in interleukin-1β-stimulated rat aortic smooth muscle cells , 2002, Journal of hypertension.
[526] C. Brideau,et al. Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique. , 1994, Canadian journal of physiology and pharmacology.
[527] P. Insel,et al. Bcl-2 protects lymphoma cells from apoptosis but not growth arrest promoted by cAMP and dexamethasone. , 2001, American journal of physiology. Cell physiology.
[528] B. Duling,et al. Gap junctions in the control of vascular function. , 2009, Antioxidants & redox signaling.
[529] O. V. Evgenov,et al. NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential , 2006, Nature Reviews Drug Discovery.
[530] P. Vanhoutte,et al. Further investigations into the endothelium‐dependent hyperpolarizing effects of bradykinin and substance P in porcine coronary artery , 2001, British journal of pharmacology.
[531] L. Barr,et al. A STUDY OF THE STRUCTURE AND DISTRIBUTION OF THE NEXUS , 1964, The Journal of cell biology.
[532] T. Gudermann,et al. Amplification of EDHF‐type vasodilatations in TRPC1‐deficient mice , 2010, British journal of pharmacology.
[533] H. Miura,et al. Human coronary arteriolar dilation to bradykinin depends on membrane hyperpolarization: contribution of nitric oxide and Ca2+-activated K+ channels. , 1999, Circulation.
[534] B. Samuelsson,et al. Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis. , 2010, Biochemical and biophysical research communications.
[535] K. Proctor,et al. Intestinal vasodilation by epoxyeicosatrienoic acids: arachidonic acid metabolites produced by a cytochrome P450 monooxygenase. , 1987, Circulation research.
[536] S. Moncada,et al. Investigation of Vascular Responses in Endothelial Nitric Oxide Synthase/Cyclooxygenase-1 Double-Knockout Mice: Key Role for Endothelium-Derived Hyperpolarizing Factor in the Regulation of Blood Pressure in Vivo , 2005, Circulation.
[537] B. Fredholm,et al. International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update , 2011, Pharmacological Reviews.
[538] C. Leo,et al. Impairment of both nitric oxide‐mediated and EDHF‐type relaxation in small mesenteric arteries from rats with streptozotocin‐induced diabetes , 2011, British journal of pharmacology.
[539] Anlong Li,et al. Heme Is a Carbon Monoxide Receptor for Large-Conductance Ca2+-Activated K+ Channels , 2005, Circulation research.
[540] R. L. Jones,et al. Focus on prostacyclin and its novel mimetics. , 1996, Trends in pharmacological sciences.
[541] W R Taylor,et al. Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy. , 1998, Hypertension.
[542] T. Lüscher,et al. Endothelium-independent relaxation and hyperpolarization to C-type natriuretic peptide in porcine coronary arteries. , 1998, Journal of cardiovascular pharmacology.
[543] T. Bolton,et al. Non‐Contractile Cells with Thin Processes Resembling Interstitial Cells of Cajal Found in the Wall of Guinea‐Pig Mesenteric Arteries , 2003, The Journal of physiology.
[544] C. Hill,et al. Vascular gap junctions and implications for hypertension , 2004, Clinical and experimental pharmacology & physiology.
[545] A. Weston,et al. Acetylcholine releases endothelium‐derived hyperpolarizing factor and EDRF from rat blood vessels , 1988, British journal of pharmacology.
[546] T. Michel,et al. The Endothelial Nitric-oxide Synthase-Caveolin Regulatory Cycle* , 1998, The Journal of Biological Chemistry.
[547] Lingyun Wu,et al. The direct effect of carbon monoxide on KCa channels in vascular smooth muscle cells , 1997, Pflügers Archiv.
[548] S. Narumiya,et al. Function of prostanoid receptors: studies on knockout mice. , 2002, Prostaglandins & other lipid mediators.
[549] M. Anand-Srivastava. Platelets from spontaneously hypertensive rats exhibit decreased expression of inhibitory guanine nucleotide regulatory protein. Relation with adenylyl cyclase activity. , 1993, Circulation research.
[550] U. Förstermann,et al. Regulation of endothelial-type NO synthase expression in pathophysiology and in response to drugs. , 2002, Nitric oxide : biology and chemistry.
[551] L. Janssen,et al. Mechanisms of hydrogen‐peroxide‐induced biphasic response in rat mesenteric artery , 2003, British journal of pharmacology.
[552] K. Griendling,et al. Reactive oxygen species in hypertension; An update. , 2004, American journal of hypertension.
[553] Y. Nakaya,et al. Exercise training improves acetylcholine-induced endothelium-dependent hyperpolarization in type 2 diabetic rats, Otsuka Long-Evans Tokushima fatty rats. , 2002, Atherosclerosis.
[554] U. Förstermann,et al. Endothelial Nitric Oxide Synthase in Vascular Disease: From Marvel to Menace , 2006, Circulation.
[555] P. Vanhoutte,et al. Morphological heterogeneity with normal expression but altered function of G proteins in porcine cultured regenerated coronary endothelial cells , 1997, British journal of pharmacology.
[556] S. Belmadani,et al. Hydrogen peroxide acts as both vasodilator and vasoconstrictor in the control of perfused mouse mesenteric resistance arteries , 2005, Journal of hypertension.
[557] P. Vanhoutte,et al. Endothelium‐dependent hyperpolarization of canine coronary smooth muscle , 1988, British journal of pharmacology.
[558] P. Vanhoutte,et al. Effects of inhibitors of arachidonic acid metabolism and calcium entry on responses to acetylcholine, potassium and norepinephrine in the isolated canine saphenous vein. , 1983, The Journal of pharmacology and experimental therapeutics.
[559] L. Ruilope,et al. Endothelial dysfunction in spontaneously hypertensive rats: consequences of chronic treatment with losartan or captopril , 1997, Journal of hypertension.
[560] K. Taylor,et al. 15-Lipoxygenase Catalytically Consumes Nitric Oxide and Impairs Activation of Guanylate Cyclase* , 1999, The Journal of Biological Chemistry.
[561] C. Durinx,et al. Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV , 2003, Critical reviews in clinical laboratory sciences.
[562] K. Morgan,et al. Mechanisms of smooth muscle contraction. , 1996, Physiological reviews.
[563] S. Moncada,et al. Nitric oxide, cytochrome C oxidase, and the cellular response to hypoxia. , 2010, Arteriosclerosis, thrombosis, and vascular biology.
[564] R. Kulmacz,et al. Thromboxane synthase: structure and function of protein and gene. , 2002, Prostaglandins & other lipid mediators.
[565] J. Falck,et al. Androgen-Dependent Hypertension Is Mediated by 20-Hydroxy-5,8,11,14-Eicosatetraenoic Acid–Induced Vascular Dysfunction: Role of Inhibitor of &kgr;B Kinase , 2011, Hypertension.
[566] G. W. Payne,et al. Histamine inhibits conducted vasodilation through endothelium‐derived NO production in arterioles of mouse skeletal muscle , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[567] J. Kuo,et al. Methyl palmitate: a potent vasodilator released in the retina. , 2010, Investigative ophthalmology & visual science.
[568] M. Yanagisawa,et al. Impaired Ventilatory Responses to Hypoxia in Mice Deficient in Endothelin-Converting-Enzyme-1 , 2001, Pediatric Research.
[569] D. Eckman,et al. Endothelium‐dependent relaxation and hyperpolarization in guinea‐pig coronary artery: role of epoxyeicosatrienoic acid , 1998, British journal of pharmacology.
[570] Hiroshi Watanabe,et al. Cyclooxygenase-dependent Vasoconstricting Factor(s) in Remodelled Rat Femoral Arteries , 2022 .
[571] A. Beaudet,et al. Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice , 1996, The Journal of experimental medicine.
[572] J. Balligand,et al. Role of Caveolar Compartmentation in Endothelium-Derived Hyperpolarizing Factor–Mediated Relaxation: Ca2+ Signals and Gap Junction Function Are Regulated by Caveolin in Endothelial Cells , 2008, Circulation.
[573] Hidezo Mori,et al. Cardioprotective role of endogenous hydrogen peroxide during ischemia-reperfusion injury in canine coronary microcirculation in vivo. , 2006, American journal of physiology. Heart and circulatory physiology.
[574] J. Falck,et al. Role of arachidonic acid lipoxygenase metabolites in acetylcholine-induced relaxations of mouse arteries. , 2011, American journal of physiology. Heart and circulatory physiology.
[575] C. Burant,et al. Glucocorticoids regulate Na+/H+ exchange expression and activity in region- and tissue-specific manner. , 1994, The American journal of physiology.
[576] F. Johnson,et al. HEME OXYGENASE-DERIVED ENDOGENOUS CARBON MONOXIDE IMPAIRS FLOW-INDUCED DILATION IN RESISTANCE VESSELS , 2007, Shock.
[577] Z. Katušić,et al. Mechanisms of Cerebral Arterial Relaxations to Hydrogen Peroxide , 1998, Stroke.
[578] D. Kass,et al. Phosphodiesterase type 5: expanding roles in cardiovascular regulation. , 2007, Circulation research.
[579] J. Cunningham,et al. Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. , 1992, The Journal of biological chemistry.
[580] I. Fleming. Molecular mechanisms underlying the activation of eNOS , 2010, Pflügers Archiv - European Journal of Physiology.
[581] S. Kunapuli,et al. P2 receptor subtypes in the cardiovascular system. , 1998, The Biochemical journal.
[582] T. Rabelink,et al. Endothelin A receptor blockade alleviates hypertension and renal lesions associated with chronic nitric oxide synthase inhibition. , 1998, Journal of the American Society of Nephrology : JASN.
[583] C. Funk,et al. The 5-lipoxygenase/leukotriene pathway in preclinical models of cardiovascular disease. , 2010, Cardiovascular research.
[584] C. Garland,et al. Activation of endothelial cell IKCa with 1‐ethyl‐2‐benzimidazolinone evokes smooth muscle hyperpolarization in rat isolated mesenteric artery , 2001, British journal of pharmacology.
[585] M. Marletta,et al. Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate. , 1988, Biochemistry.
[586] M. Kunitomo,et al. Excessive salt or cholesterol intake alters the balance among endothelium-derived factors released from renal arteries in spontaneously hypertensive rats. , 1999, Journal of cardiovascular pharmacology.
[587] K. Ishii,et al. Identification, cloning and expression of rabbit vascular smooth muscle Kv1.5 and comparison with native delayed rectifier K+ current , 1999, The Journal of physiology.
[588] M. Biel,et al. Structure and function of cyclic nucleotide-gated channels. , 1999, Reviews of physiology, biochemistry and pharmacology.
[589] C. Busch,et al. Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a New Activator of KCa2 and KCa3.1 Potassium Channels, Potentiates the Endothelium-Derived Hyperpolarizing Factor Response and Lowers Blood Pressure , 2009, Molecular Pharmacology.
[590] T. Totoki,et al. NOS II Inhibition Restores Attenuation of Endothelium-Dependent Hyperpolarization in Rat Mesenteric Artery Exposed to Lipopolysaccharide , 2004, Journal of cardiovascular pharmacology.
[591] H. Kontos,et al. H2O2 and endothelium-dependent cerebral arteriolar dilation. Implications for the identity of endothelium-derived relaxing factor generated by acetylcholine. , 1990, Hypertension.
[592] H. Holzhütter,et al. A kinetic model for the interaction of nitric oxide with a mammalian lipoxygenase. , 1997, European journal of biochemistry.
[593] B. Jugdutt. Nitric Oxide and Cardioprotection During Ischemia-Reperfusion , 2002, Heart Failure Reviews.
[594] A. Ahluwalia,et al. Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor. , 2008, The Journal of endocrinology.
[595] L. Navar,et al. Actions of epoxygenase metabolites on the preglomerular vasculature. , 1996, Journal of the American Society of Nephrology : JASN.
[596] Chao-shu Tang,et al. Frontiers in Research Review: The Pathophysiological Significance of Sulphur-Containing Gases Significance of endogenous sulphur-containing gases in the cardiovascular system , 2010 .
[597] G. Christ,et al. Gap junctions in vascular tissues. Evaluating the role of intercellular communication in the modulation of vasomotor tone. , 1996, Circulation research.
[598] B. Duling,et al. Connexin40 and connexin43 in mouse aortic endothelium: evidence for coordinated regulation. , 2006, American journal of physiology. Heart and circulatory physiology.
[599] C. Garland,et al. Recent developments in vascular endothelial cell transient receptor potential channels. , 2005, Circulation research.
[600] P. Vanhoutte,et al. C‐type natriuretic peptide and endothelium‐dependent hyperpolarization in the guinea‐pig carotid artery , 2008, British journal of pharmacology.
[601] A. Gurney,et al. Two-Pore Domain K Channel, TASK-1, in Pulmonary Artery Smooth Muscle Cells , 2003, Circulation research.
[602] J. Garthwaite,et al. Probing the presence of the ligand‐binding haem in cellular nitric oxide receptors , 2008, British journal of pharmacology.
[603] G. Reaven. Multiple CHD risk factors in type 2 diabetes: beyond hyperglycaemia , 2002, Diabetes, obesity & metabolism.
[604] I. Fleming,et al. Epoxyeicosatrienoic acids and endothelium-dependent responses , 2010, Pflügers Archiv - European Journal of Physiology.
[605] H. Lenasi. The role of nitric oxide‐ and prostacyclin‐independent vasodilatation in the human cutaneous microcirculation: effect of cytochrome P450 2C9 inhibition , 2009, Clinical physiology and functional imaging.
[606] J. Hodgson,et al. Urinary 20-Hydroxyeicosatetraenoic Acid Is Associated With Endothelial Dysfunction in Humans , 2004, Circulation.
[607] H. Drummond,et al. Inhibition of 20-HETE production contributes to the vascular responses to nitric oxide. , 1997, Hypertension.
[608] A. K. Singh,et al. Pharmacological activation of cloned intermediate- and small-conductance Ca(2+)-activated K(+) channels. , 2000, American journal of physiology. Cell physiology.
[609] C. Marcocci,et al. The sulfaphenazole-sensitive pathway acts as a compensatory mechanism for impaired nitric oxide availability in patients with primary hyperparathyroidism. Effect of surgical treatment. , 2010, The Journal of clinical endocrinology and metabolism.
[610] P. Ramwell,et al. The effect of prostacyclin on the human umbilical artery. , 1978, Prostaglandins.
[611] J. Balligand,et al. eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues. , 2009, Physiological reviews.
[612] G. Burnstock,et al. Ultrastructural localization of nitric oxide synthase and endothelin in the renal and mesenteric arteries of the golden hamster: differences during and after arousal from hibernation. , 1999, Endothelium : journal of endothelial cell research.
[613] C. Garland,et al. Modulation of Endothelial Cell KCa3.1 Channels During Endothelium-Derived Hyperpolarizing Factor Signaling in Mesenteric Resistance Arteries , 2008, Circulation research.
[614] B. Nilius,et al. Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels , 2003, Nature.
[615] R. Hogg,et al. Action of niflumic acid on evoked and spontaneous calcium‐activated chloride and potassium currents in smooth muscle cells from rabbit portal vein , 1994, British journal of pharmacology.
[616] L. Audoly,et al. Role of microsomal prostaglandin E synthase 1 in the kidney. , 2007, Journal of the American Society of Nephrology : JASN.
[617] Lei Zhao,et al. Lipoxygenase genes and their targeted disruption. , 2002, Prostaglandins & other lipid mediators.
[618] H. Miura,et al. Hydrogen Peroxide Inhibits Cytochrome P450 Epoxygenases: Interaction Between Two Endothelium-Derived Hyperpolarizing Factors , 2008, Circulation research.
[619] A. Malik,et al. Transport across the endothelium: regulation of endothelial permeability. , 2006, Handbook of experimental pharmacology.
[620] G. Vazquez,et al. The Constitutive Function of Native TRPC3 Channels Modulates Vascular Cell Adhesion Molecule-1 Expression in Coronary Endothelial Cells Through Nuclear Factor &kgr;B Signaling , 2010, Circulation research.
[621] K. Honn,et al. Overexpression of platelet-type 12-lipoxygenase promotes tumor cell survival by enhancing alpha(v)beta(3) and alpha(v)beta(5) integrin expression. , 2003, Cancer research.
[622] W. Campbell,et al. Epoxyeicosatrienoic acids activate K+ channels in coronary smooth muscle through a guanine nucleotide binding protein. , 1997, Circulation research.
[623] R. Hammer,et al. Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. , 1998, Development.
[624] J. Vane,et al. Cyclooxygenases 1 and 2. , 1998, Annual review of pharmacology and toxicology.
[625] J. Friedman,et al. Abnormal osmotic regulation in trpv4-/- mice , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[626] L. Ghiadoni,et al. Aging and endothelial function in normotensive subjects and patients with essential hypertension. , 1995, Circulation.
[627] N. Marrion,et al. Small-Conductance, Calcium-Activated Potassium Channels from Mammalian Brain , 1996, Science.
[628] J. Pernow,et al. Contribution of endothelin to the coronary vasoconstriction in the isolated rat heart induced by nitric oxide synthase inhibition. , 1998, Acta physiologica Scandinavica.
[629] R. Hammer,et al. Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice , 1994, Cell.
[630] Qun Gao,et al. Mitochondrial-derived hydrogen peroxide inhibits relaxation of bovine coronary arterial smooth muscle to hypoxia through stimulation of ERK MAP kinase. , 2009, American journal of physiology. Heart and circulatory physiology.
[631] Shenyuan L. Zhang,et al. Store-dependent and -independent Modes Regulating Ca2+ Release-activated Ca2+ Channel Activity of Human Orai1 and Orai3* , 2008, Journal of Biological Chemistry.
[632] W. Campbell,et al. Role of arachidonic acid lipoxygenase metabolites in the regulation of vascular tone. , 2009, American journal of physiology. Heart and circulatory physiology.
[633] P. Vanhoutte,et al. Cannabinoid CB1 receptor and endothelium‐dependent hyperpolarization in guinea‐pig carotid, rat mesenteric and porcine coronary arteries , 1998, British journal of pharmacology.
[634] G. Gross,et al. Roles of Epoxyeicosatrienoic Acids in Vascular Regulation and Cardiac Preconditioning , 2007, Journal of cardiovascular pharmacology.
[635] W. Campbell,et al. 11,12-Epoxyeicosatrienoic acid stimulates endogenous mono-ADP-ribosylation in bovine coronary arterial smooth muscle. , 1999, Circulation research.
[636] X. Fang,et al. Epoxyeicosatrienoic acids increase intracellular calcium concentration in vascular smooth muscle cells. , 1999, Hypertension.
[637] N. Belyaev,et al. Amyloid-degrading enzymes as therapeutic targets in Alzheimer's disease. , 2008, Current Alzheimer research.
[638] Patrick M. Sexton,et al. International Union of Pharmacology. XXXII. The Mammalian Calcitonin Gene-Related Peptides, Adrenomedullin, Amylin, and Calcitonin Receptors , 2002, Pharmacological Reviews.
[639] T. Itoh,et al. Mechanisms of hydrogen peroxide-induced relaxation in rabbit mesenteric small artery. , 2001, European journal of pharmacology.
[640] M. Marletta,et al. Synthesis of nitrite and nitrate in murine macrophage cell lines. , 1987, Cancer research.
[641] R. Busse,et al. Pulsatile stretch in coronary arteries elicits release of endothelium-derived hyperpolarizing factor: a modulator of arterial compliance. , 1998, Circulation research.
[642] T. Michel,et al. Life history of eNOS: partners and pathways. , 2007, Cardiovascular research.
[643] Soohee Lee,et al. Endothelin-3-converting Enzyme Activity of the KEL1 and KEL6 Phenotypes of the Kell Blood Group System* , 2006, Journal of Biological Chemistry.
[644] R. Paul,et al. Ca2+ clearance and contractility in vascular smooth muscle: evidence from gene-altered murine models. , 2008, Journal of molecular and cellular cardiology.
[645] W. Hsueh,et al. Expression and Function of PPARγ in Rat and Human Vascular Smooth Muscle Cells , 2000 .
[646] J. Falck,et al. 14,15-Epoxyeicosatrienoic Acid Represents a Transferable Endothelium-Dependent Relaxing Factor in Bovine Coronary Arteries , 2005, Hypertension.
[647] M. Lazdunski,et al. The endocannabinoid anandamide is a direct and selective blocker of the background K+ channel TASK‐1 , 2001, The EMBO journal.
[648] M. Nangle,et al. Effects of interleukin‐6 treatment on neurovascular function, nerve perfusion and vascular endothelium in diabetic rats , 2010, Diabetes, obesity & metabolism.
[649] Y. Boo,et al. Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases. , 2003, American journal of physiology. Cell physiology.
[650] J. Falck,et al. Epoxygenase Metabolites Contribute to Nitric Oxide-Independent Afferent Arteriolar Vasodilation in Response to Bradykinin , 2001, Journal of Vascular Research.
[651] P. Kubes,et al. Potassium‐ and acetylcholine‐induced vasorelaxation in mice lacking endothelial nitric oxide synthase , 2000, British journal of pharmacology.
[652] L. Ghiadoni,et al. Endothelial dysfunction in hypertension. , 2001, Journal of cardiovascular pharmacology.
[653] H. Rockman,et al. A role for the thromboxane receptor in L-NAME hypertension. , 2008, American journal of physiology. Renal physiology.
[654] Z. Ungvari,et al. Mediation of EDHF‐Induced Reduction of Smooth Muscle [Ca2+]i and Arteriolar Dilation by K+ Channels, 5,6‐EET, and Gap Junctions , 2001, Microcirculation.
[655] F. Russell. Urotensin II in cardiovascular regulation , 2008, Vascular health and risk management.
[656] D. Harder,et al. Cerebral Capillary Endothelial Cell Mitogenesis and Morphogenesis Induced by Astrocytic Epoxyeicosatrienoic Acid , 2002, Stroke.
[657] M. Gladwin,et al. Nitrite as regulator of hypoxic signaling in mammalian physiology , 2009, Medicinal research reviews.
[658] C. Cavadas,et al. NPY, NPY receptors, and DPP IV activity are modulated by LPS, TNF-α and IFN-γ in HUVEC , 2003, Regulatory Peptides.
[659] G. Saade,et al. Citrulline does not relax isolated rat and rabbit vessels , 2000, British journal of pharmacology.
[660] H. Shirahase,et al. Endothelium‐dependent contraction in intrapulmonary arteries: mediation by endothelial NK1 receptors and TXA2 , 1995, British journal of pharmacology.
[661] N. Severs,et al. Individual gap junction plaques contain multiple connexins in arterial endothelium. , 1998, Circulation research.
[662] B. Kalyanaraman,et al. The Role of Tetrahydrobiopterin in Superoxide Generation from eNOS: Enzymology and Physiological Implications , 2003, Free radical research.
[663] C. Leffler,et al. Carbon Monoxide Dilates Cerebral Arterioles by Enhancing the Coupling of Ca2+ Sparks to Ca2+-Activated K+ Channels , 2002, Circulation research.
[664] V. Stein,et al. Molecular structure and physiological function of chloride channels. , 2002, Physiological reviews.
[665] I. Laher,et al. Store‐operated calcium entry in vascular smooth muscle , 2008, British journal of pharmacology.
[666] F. Fyhrquist,et al. Renin‐angiotensin system revisited , 2008, Journal of internal medicine.
[667] B. Koller,et al. Inhibition of 5-lipoxygenase-activating protein (FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension in hypoxic rats. , 1996, The Journal of clinical investigation.
[668] R. Busse,et al. Calcium influx into endothelial cells and formation of endothelium-derived relaxing factor is controlled by the membrane potential , 1990, Pflügers Archiv.
[669] J. Madden,et al. Cyclooxygenase contracting factors and altered pulmonary vascular responses in chronically hypoxic newborn pigs. , 2002, Journal of applied physiology.
[670] A. Gabrielsen,et al. Thromboxane synthase expression and thromboxane A2 production in the atherosclerotic lesion , 2010, Journal of Molecular Medicine.
[671] B. Hierck,et al. The role of shear stress on ET-1, KLF2, and NOS-3 expression in the developing cardiovascular system of chicken embryos in a venous ligation model. , 2007, Physiology.
[672] G. G. Emerson,et al. Electrical Coupling Between Endothelial Cells and Smooth Muscle Cells in Hamster Feed Arteries: Role in Vasomotor Control , 2000, Circulation research.
[673] B. Larsen,et al. Pharmacological Characterization of the New Stable Antiarrhythmic Peptide Analog Ac-d-Tyr-d-Pro-d-Hyp-Gly-d-Ala-Gly-NH2 (ZP123): In Vivo and in Vitro Studies , 2003, Journal of Pharmacology and Experimental Therapeutics.
[674] M. Crackower,et al. The role of ACE2 in cardiovascular physiology. , 2003, Trends in cardiovascular medicine.
[675] G. FitzGerald,et al. Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation. , 2001, The Journal of clinical investigation.
[676] Lijun Li,et al. Neuropeptide Y: multiple receptors and multiple roles in cardiovascular diseases. , 2004, Current opinion in investigational drugs.
[677] L. Ytrebø,et al. Adenosine instead of supranormal potassium in cardioplegic solution preserves endothelium-derived hyperpolarization factor-dependent vasodilation. , 2008, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.
[678] S. Snyder,et al. Heme oxygenase 2: endothelial and neuronal localization and role in endothelium-dependent relaxation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[679] D. Stec,et al. Heme oxygenase-1 induction does not improve vascular relaxation in angiotensin II hypertensive mice. , 2008, American journal of hypertension.
[680] David S. Park,et al. Caveolae-deficient Endothelial Cells Show Defects in the Uptake and Transport of Albumin in Vivo * , 2001, The Journal of Biological Chemistry.
[681] Zhiyong Lin,et al. Kruppel-Like Factor 2 as a Novel Mediator of Statin Effects in Endothelial Cells , 2005, Circulation.
[682] A. Brash,et al. Oxygenation of biological membranes by the pure reticulocyte lipoxygenase. , 1990, The Journal of biological chemistry.
[683] S. Yang,et al. Hyperpolarization contributes to vascular hyporeactivity in rats with lipopolysaccharide-induced endotoxic shock. , 2000, Life sciences.
[684] F. Johnson,et al. Carbon monoxide promotes endothelium-dependent constriction of isolated gracilis muscle arterioles. , 2003, American journal of physiology. Regulatory, integrative and comparative physiology.
[685] R. Sotníková. Investigation of the mechanisms underlying H2O2-evoked contraction in the isolated rat aorta. , 1998, General pharmacology.
[686] B. Masters,et al. 20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries. , 1993, Circulation research.
[687] P. Vanhoutte,et al. Heterogeneous Behavior of the Canine Arterial and Venous Wall: Importance of the Endothelium , 1982, Circulation research.
[688] P. Vanhoutte,et al. Characterization of a charybdotoxin‐sensitive intermediate conductance Ca2+‐activated K+ channel in porcine coronary endothelium: relevance to EDHF , 2002, British journal of pharmacology.
[689] R. Langenbach,et al. Phenotypes of the COX-deficient mice indicate physiological and pathophysiological roles for COX-1 and COX-2. , 2002, Prostaglandins & other lipid mediators.
[690] R. Busse,et al. Cytochrome P450 2C9-induced Endothelial Cell Proliferation Involves Induction of Mitogen-activated Protein (MAP) Kinase Phosphatase-1, Inhibition of the c-Jun N-terminal Kinase, and Up-regulation of Cyclin D1* , 2002, The Journal of Biological Chemistry.
[691] A. Fujimura,et al. TRPV4 as a flow sensor in flow-dependent K+ secretion from the cortical collecting duct. , 2007, American journal of physiology. Renal physiology.
[692] K. Sanders. Invited review: mechanisms of calcium handling in smooth muscles. , 2001, Journal of applied physiology.
[693] R. Busse,et al. Differential role of extra‐ and intracellular calcium in the release of EDRF and prostacyclin from cultured endothelial cells , 1988, British journal of pharmacology.
[694] H. Sarau,et al. Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14 , 1999, Nature.
[695] Y. Izumiya,et al. Activated Endocannabinoid System in Coronary Artery Disease and Antiinflammatory Effects of Cannabinoid 1 Receptor Blockade on Macrophages , 2009, Circulation.
[696] Lijun Li,et al. Neuropeptide Y: a new mediator linking sympathetic nerves, blood vessels and immune system? , 2003, Canadian journal of physiology and pharmacology.
[697] D. Kendall,et al. The complexities of the cardiovascular actions of cannabinoids , 2004, British journal of pharmacology.
[698] M. Kähönen,et al. Exercise enhances vasorelaxation in experimental obesity associated hypertension. , 1999, Cardiovascular research.
[699] J. Vane,et al. The endothelial cell as a metabolic and endocrine organ , 1987 .
[700] H. Suzuki,et al. Calcium dependency of the endothelium‐dependent hyperpolarization in smooth muscle cells of the rabbit carotid artery. , 1990, The Journal of physiology.
[701] N. Bishara,et al. Glucose enhances expression of TRPC1 and calcium entry in endothelial cells. , 2010, American journal of physiology. Heart and circulatory physiology.
[702] H. Vaudry,et al. Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: 20 Years after the Discovery , 2009, Pharmacological Reviews.
[703] Kazuki Nakamura,et al. Chronic nitric oxide exposure alters the balance between endothelium-derived relaxing factors released from rat renal arteries: prevention by treatment with NOX-100, a NO scavenger. , 2004, Life sciences.
[704] A. Brash,et al. Lipoxygenase-catalyzed formation of R-configuration hydroperoxides. , 2002, Prostaglandins & other lipid mediators.
[705] M. Peach,et al. Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism. , 1983, The Journal of pharmacology and experimental therapeutics.
[706] T. Lüscher,et al. Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide. , 1990, The Journal of clinical investigation.
[707] Takashi Saito,et al. Role for Hydrogen Peroxide in Flow-Induced Dilation of Human Coronary Arterioles , 2003, Circulation research.
[708] J. Degen,et al. Structural and Functional Diversity of Connexin Genes in the Mouse and Human Genome , 2002, Biological chemistry.
[709] K. Kamata,et al. IGF-I-induced enhancement of contractile response in organ-cultured aortae from diabetic rats is mediated by sustained thromboxane A2 release from endothelial cells. , 2005, The Journal of endocrinology.
[710] W. Jackson. Ion channels and vascular tone. , 2000, Hypertension.
[711] S. Heinemann,et al. Reactive oxygen species impair Slo1 BK channel function by altering cysteine-mediated calcium sensing , 2004, Nature Structural &Molecular Biology.
[712] V. Bolotina. Orai, STIM1 and iPLA2β: a view from a different perspective , 2008, The Journal of physiology.
[713] L. Ghiadoni,et al. Age-Related Reduction of NO Availability and Oxidative Stress in Humans , 2001, Hypertension.
[714] L. Liaudet,et al. Nitric oxide and peroxynitrite in health and disease. , 2007, Physiological reviews.
[715] P. Seeburg,et al. Respiration and parturition affected by conditional overexpression of the Ca2+-activated K+ channel subunit, SK3. , 2000, Science.
[716] N. Alp,et al. Mechanisms for the role of tetrahydrobiopterin in endothelial function and vascular disease. , 2007, Clinical science.
[717] G. Burnstock,et al. Endothelium of human umbilical blood vessels: ultrastructural immunolocalization of neuropeptides. , 1993, Journal of vascular research.
[718] J. Catravas,et al. Endothelial nitric oxide (NO) and its pathophysiologic regulation. , 2008, Vascular pharmacology.
[719] Tony J. Verbeuren. Terutroban et récepteurs TP endothéliaux dans l’athérogenèse , 2006 .
[720] Y. Sasaguri,et al. Spontaneous Myocardial Infarction in Mice Lacking All Nitric Oxide Synthase Isoforms , 2008, Circulation.
[721] N. L. Alsip,et al. Oestrous cycle and pregnancy alter the reactivity of the rat uterine vasculature. , 2000, Human reproduction.
[722] J. Banting,et al. Acute hypertension after nitric oxide synthase inhibition is mediated primarily by increased endothelin vasoconstriction , 1996, Journal of hypertension.
[723] W. Cole,et al. ATP‐Sensitive K+ Channels of Vascular Smooth Muscle Cells , 2003, Journal of cardiovascular electrophysiology.
[724] S. Grissmer,et al. Blockage of intermediate-conductance Ca2+-activated K+ channels inhibit human pancreatic cancer cell growth in vitro. , 2004, Molecular pharmacology.
[725] L. Ghiadoni,et al. Cyclooxygenase inhibition restores nitric oxide activity in essential hypertension. , 1997, Hypertension.
[726] P. Vanhoutte,et al. Role of gap junctions in the responses to EDHF in rat and guinea‐pig small arteries , 1999, British journal of pharmacology.
[727] D. Kohan. SYMPOSIUM Experimental Biology 1995 Endothelin Receptors: Role in Renal Function and Dysfunction ENDOTHELINS: RENAL TUBULE SYNTHESIS AND ACTIONS , 1996, Clinical and experimental pharmacology & physiology.
[728] S. Watts. Endothelin receptors: what's new and what do we need to know? , 2010, American journal of physiology. Regulatory, integrative and comparative physiology.
[729] P. Krause,et al. Prostaglandin E2 at new glance: novel insights in functional diversity offer therapeutic chances. , 2010, The international journal of biochemistry & cell biology.
[730] Yu Huang,et al. Thromboxane prostanoid receptor activation impairs endothelial nitric oxide-dependent vasorelaxations: the role of Rho kinase. , 2009, Biochemical pharmacology.
[731] G. Osol,et al. Estrogen replacement enhances EDHF‐mediated vasodilation of mesenteric and uterine resistance arteries: role of endothelial cell Ca2+ , 2009, American journal of physiology. Endocrinology and metabolism.
[732] T. Münzel,et al. Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension. , 2008, Antioxidants & redox signaling.
[733] P. Kaminski,et al. Stretch Enhances Contraction of Bovine Coronary Arteries via an NAD(P)H Oxidase–Mediated Activation of the Extracellular Signal–Regulated Kinase Mitogen-Activated Protein Kinase Cascade , 2003, Circulation research.
[734] I. Grgic,et al. Shear stress-induced up-regulation of the intermediate-conductance Ca(2+)-activated K(+) channel in human endothelium. , 2003, Cardiovascular research.
[735] P. Vanhoutte,et al. Mediation by M3‐muscarinic receptors of both endothelium‐dependent contraction and relaxation to acetylcholine in the aorta of the spontaneously hypertensive rat , 1994, British journal of pharmacology.
[736] Hiroaki Shimokawa,et al. Electron Spin Resonance Detection of Hydrogen Peroxide as an Endothelium-Derived Hyperpolarizing Factor in Porcine Coronary Microvessels , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[737] M. Kähönen,et al. Influence of gender on control of arterial tone in experimental hypertension. , 1998, American journal of physiology. Heart and circulatory physiology.
[738] K. Sato,et al. Relationship between quin2-determined cytosolic [Ca2+] and sweat secretion. , 1988, The American journal of physiology.
[739] K. Okumura,et al. Altered gene expression of prostacyclin synthase and prostacyclin receptor in the thoracic aorta of spontaneously hypertensive rats. , 1999, Cardiovascular research.
[740] T. Coffman,et al. Thromboxane receptor mediates renal vasoconstriction and contributes to acute renal failure in endotoxemic mice. , 2004, Journal of the American Society of Nephrology : JASN.
[741] P. Verhamme,et al. THE PIVOTAL ROLE OF THE ENDOTHELIUM IN HAEMOSTASIS AND THROMBOSIS , 2006, Acta clinica Belgica.
[742] A. Bonev,et al. Kir2.1 encodes the inward rectifier potassium channel in rat arterial smooth muscle cells , 1999, The Journal of physiology.
[743] L. Ruilope,et al. Atorvastatin prevents glomerulosclerosis and renal endothelial dysfunction in hypercholesterolaemic rabbits. , 2001, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[744] V. Cachofeiro,et al. Increased Vascular Responsiveness to Bradykinin in Kidneys of Spontaneously Hypertensive Rats Effect of Nω‐Nitro‐L‐Arginine , 1991, Hypertension.
[745] D. Newby,et al. The vascular effects of rotigaptide in vivo in man. , 2008, Biochemical pharmacology.
[746] F. Ruschitzka,et al. Selective COX-2 Inhibition Improves Endothelial Function in Coronary Artery Disease , 2003, Circulation.
[747] H. Tai,et al. Thromboxanes: synthase and receptors. , 1998, Journal of biomedical science.
[748] P. Vanhoutte,et al. Mechanisms underlying ATP-induced endothelium-dependent contractions in the SHR aorta. , 2007, European journal of pharmacology.
[749] J. Falck,et al. Metabolism of adrenic acid to vasodilatory 1α,1β-dihomo-epoxyeicosatrienoic acids by bovine coronary arteries , 2007 .
[750] P. Moore,et al. Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide. , 2006, Biochemical and biophysical research communications.
[751] A. Yim,et al. Alteration of cellular electrophysiologic properties in porcine pulmonary microcirculation after preservation with University of Wisconsin and Euro-Collins solutions. , 2004, The Annals of thoracic surgery.
[752] R. Zatz,et al. Linking oxidative stress, the renin-angiotensin system, and hypertension. , 2011, Hypertension.
[753] R. Marsault,et al. Bradykinin‐induced contractions of canine saphenous veins: mediation by B2 receptors and involvement of eicosanoids , 1997, British journal of pharmacology.
[754] J. Gelfand,et al. Seeing red: flushing out instigators of niacin-associated skin toxicity. , 2010, The Journal of clinical investigation.
[755] C. Aalkjaer,et al. NS309 restores EDHF‐type relaxation in mesenteric small arteries from type 2 diabetic ZDF rats , 2010, British journal of pharmacology.
[756] J. Tfelt‐Hansen,et al. Novel Role of the Calcium-Sensing Receptor in Blood Pressure Modulation , 2008, Hypertension.
[757] A. Mügge,et al. Endothelial‐derived superoxide anions in pig coronary arteries: evidence from lucigenin chemiluminescence and histochemical techniques. , 1997, The Journal of physiology.
[758] I. Leusen,et al. Endothelium-dependent relaxation and hyperpolarization in aorta from control and renal hypertensive rats. , 1992, Circulation research.
[759] R. Busse,et al. Cytochrome P450 2C is an EDHF synthase in coronary arteries , 1999, Nature.
[760] J. Soboloff,et al. Role of STIM and Orai proteins in the store-operated calcium signaling pathway. , 2007, Cell calcium.
[761] A. Davenport,et al. Secretory pathways in endothelin synthesis , 1999, British journal of pharmacology.
[762] S. Tunaru,et al. Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice. , 2010, The Journal of clinical investigation.
[763] H. Itoh,et al. [Natriuretic peptide family]. , 2000, Nihon rinsho. Japanese journal of clinical medicine.
[764] S. Fujimoto,et al. Weibel‐Palade bodies as a storage site of calcitonin gene‐related peptide and endothelin‐1 in blood vessels of the rat carotid body , 1997, The Anatomical record.
[765] M. Jensen,et al. Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study , 2006, The Lancet.
[766] Y. Ueta,et al. Adrenomedullin, an autocrine mediator of blood-brain barrier function. , 2003, Hypertension research : official journal of the Japanese Society of Hypertension.
[767] D. Bredt. Endogenous nitric oxide synthesis: biological functions and pathophysiology. , 1999, Free radical research.
[768] P. Pratt,et al. Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. , 1996, Circulation research.
[769] K. Fujii,et al. Decreased 4-aminopyridine sensitive K+ currents in endothelial cells from hypertensive rats. , 2002, Hypertension research : official journal of the Japanese Society of Hypertension.
[770] C. Page,et al. Phosphodiesterase inhibitors , 2006, British journal of pharmacology.
[771] A. Takeshita,et al. Influence of Diabetes Mellitus, Hypercholesterolemia, and Their Combination on EDHF-Mediated Responses in Mice , 2005, Journal of cardiovascular pharmacology.
[772] W. Aird. Phenotypic Heterogeneity of the Endothelium: II. Representative Vascular Beds , 2007, Circulation research.
[773] R. Wilensky,et al. Hypercholesterolemia Suppresses Inwardly Rectifying K+ Channels in Aortic Endothelium In Vitro and In Vivo , 2006, Circulation research.
[774] C. Triggle,et al. Endothelial dysfunction in the streptozotocin‐induced diabetic apoE‐deficient mouse , 2005, British journal of pharmacology.
[775] K. Krause,et al. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. , 2007, Physiological reviews.
[776] R. Busse,et al. 20-HETE–Induced Contraction of Small Coronary Arteries Depends on the Activation of Rho-Kinase , 2003, Hypertension.
[777] T. Stevens,et al. On the endothelial cell ISOC , 2003 .
[778] K. Pritchard,et al. Bradykinin-Induced Dilation of Human Coronary Arterioles Requires NADPH Oxidase–Derived Reactive Oxygen Species , 2009, Arteriosclerosis, thrombosis, and vascular biology.
[779] M. Iida,et al. Effects of angiotensin II receptor antagonist on impaired endothelium-dependent and endothelium-independent relaxations in type II diabetic rats , 2006, Journal of hypertension.
[780] K. Kamata,et al. Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats , 2000, Naunyn-Schmiedeberg's Archives of Pharmacology.
[781] S. Moncada,et al. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo , 1990, British journal of pharmacology.
[782] Y. Pinto,et al. Impaired coronary endothelial function in a rat model of spontaneous albuminuria. , 2002, Kidney international.
[783] J. Foley,et al. Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP-Sensitive K+ Channels and p42/p44 MAPK Pathway , 2004, Circulation research.
[784] Bruce D. Hammock,et al. Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases , 2009, Nature Reviews Drug Discovery.
[785] S. Moncada,et al. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor , 1986, Nature.
[786] G. Garcı́a-Cardeña,et al. Endothelial Nitric Oxide Synthase Is Regulated by Tyrosine Phosphorylation and Interacts with Caveolin-1* , 1996, The Journal of Biological Chemistry.
[787] J. Jukema,et al. Negative effects of rofecoxib treatment on cardiac function after ischemia-reperfusion injury in APOE3Leiden mice are prevented by combined treatment with thromboxane prostanoid-receptor antagonist S18886 (terutroban). , 2008, Critical care medicine.
[788] J. Balligand,et al. Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[789] C. Garland,et al. Enhanced spontaneous Ca2+ events in endothelial cells reflect signalling through myoendothelial gap junctions in pressurized mesenteric arteries. , 2008, Cell calcium.
[790] T. Fülöp,et al. Increased Cyclooxygenase-2 Expression and Prostaglandin-Mediated Dilation in Coronary Arterioles of Patients With Diabetes Mellitus , 2006, Circulation research.
[791] B. Hornig,et al. Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients. , 1997, Circulation.
[792] L. Muller,et al. Heterodimerization of Endothelin-converting Enzyme-1 Isoforms Regulates the Subcellular Distribution of This Metalloprotease* , 2003, The Journal of Biological Chemistry.
[793] G. Edwards,et al. Impairment of endothelial SKCa channels and of downstream hyperpolarizing pathways in mesenteric arteries from spontaneously hypertensive rats , 2010, British journal of pharmacology.
[794] R. Andriantsitohaina,et al. Characterization of endothelium‐derived relaxing factors released by bradykinin in human resistance arteries , 1997, British journal of pharmacology.
[795] J. Falck,et al. Identification of 15-hydroxy-11,12-epoxyeicosatrienoic acid as a vasoactive 15-lipoxygenase metabolite in rabbit aorta. , 2008, American journal of physiology. Heart and circulatory physiology.
[796] D. E. Goldman. POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES , 1943, The Journal of general physiology.
[797] D. Cook,et al. Mechanisms of arachidonic acid-induced contractions of canine cerebral arteries. , 1987, European journal of pharmacology.
[798] A. Moreno,et al. Gap junction channel gating modulated through protein phosphorylation. , 2007, Progress in biophysics and molecular biology.
[799] Z. Katušić,et al. Thromboxane A2 Receptor Antagonists Inhibit Endothelium‐Dependent Contractions , 1990, Hypertension.
[800] R. Touyz,et al. Reactive oxygen species and vascular remodelling in hypertension: still alive. , 2006, The Canadian journal of cardiology.
[801] P. Buttrick,et al. Increased contractility and altered Ca(2+) transients of mouse heart myocytes conditionally expressing PKCbeta. , 2001, American journal of physiology. Cell physiology.
[802] Y. Sasaguri,et al. Severe dyslipidaemia, atherosclerosis, and sudden cardiac death in mice lacking all NO synthases fed a high-fat diet. , 2010, Cardiovascular research.
[803] A. Takeshita,et al. Importance of endothelium-derived hyperpolarizing factor in human arteries. , 1997, The Journal of clinical investigation.
[804] I. Grgic,et al. Selective Blockade of the Intermediate-Conductance Ca2+-Activated K+ Channel Suppresses Proliferation of Microvascular and Macrovascular Endothelial Cells and Angiogenesis In Vivo , 2005, Arteriosclerosis, thrombosis, and vascular biology.
[805] R. Natarajan,et al. A leukocyte type of 12-lipoxygenase is expressed in human vascular and mononuclear cells. Evidence for upregulation by angiotensin II. , 1995, Arteriosclerosis, thrombosis, and vascular biology.
[806] D. Rader,et al. Microsomal Prostaglandin E Synthase-1 Deletion Suppresses Oxidative Stress and Angiotensin II–Induced Abdominal Aortic Aneurysm Formation , 2008, Circulation.
[807] P. Huang,et al. An endothelium-derived hyperpolarizing factor distinct from NO and prostacyclin is a major endothelium-dependent vasodilator in resistance vessels of wild-type and endothelial NO synthase knockout mice. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[808] A. Giaid,et al. Role of urotensin II in health and disease. , 2010, American journal of physiology. Regulatory, integrative and comparative physiology.
[809] J. Blanco-Rivero,et al. Long-term fenofibrate treatment impairs endothelium-dependent dilation to acetylcholine by altering the cyclooxygenase pathway. , 2007, Cardiovascular research.
[810] J. Gamble,et al. Heme Oxygenase-1 Increases Endothelial Progenitor Cells , 2009, Arteriosclerosis, thrombosis, and vascular biology.
[811] M. Claeys,et al. Endothelium-dependent inhibitory effects of acetylcholine, adenosine triphosphate, thrombin and arachidonic acid in the canine femoral artery. , 1982, The Journal of pharmacology and experimental therapeutics.
[812] D. Harder,et al. 20-Hydroxyeicosatetraenoic Acid-induced Vasoconstriction and Inhibition of Potassium Current in Cerebral Vascular Smooth Muscle Is Dependent on Activation of Protein Kinase C* , 1997, The Journal of Biological Chemistry.
[813] D. Power,et al. Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation. , 2007, Journal of molecular and cellular cardiology.
[814] L. Rubin,et al. Differential effects of stable prostacyclin analogs on smooth muscle proliferation and cyclic AMP generation in human pulmonary artery. , 2002, American journal of respiratory cell and molecular biology.
[815] H. Coleman,et al. Involvement of Myoendothelial Gap Junctions in the Actions of Endothelium-Derived Hyperpolarizing Factor , 2002, Circulation research.
[816] L. Ghiadoni,et al. Identification of a cytochrome P450 2C9-derived endothelium-derived hyperpolarizing factor in essential hypertensive patients. , 2006, Journal of the American College of Cardiology.
[817] M. Yanagisawa,et al. Endothelin-converting Enzyme-2 Is a Membrane-bound, Phosphoramidon-sensitive Metalloprotease with Acidic pH Optimum (*) , 1995, The Journal of Biological Chemistry.
[818] D. Pimentel,et al. S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide , 2004, Nature Medicine.
[819] W. Durante,et al. ARGINASE: A CRITICAL REGULATOR OF NITRIC OXIDE SYNTHESIS AND VASCULAR FUNCTION , 2007, Clinical and experimental pharmacology & physiology.
[820] T. Sakurai,et al. Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor , 1990, Nature.
[821] B. Schutte,et al. Expression of CLCN voltage-gated chloride channel genes in human blood vessels. , 1999, Journal of molecular and cellular cardiology.
[822] R. Paul,et al. Eicosonoid metabolism and beta-adrenergic mechanisms in coronary arterial smooth muscle: potential compartmentation of cAMP. , 1986, The American journal of physiology.
[823] K. Kane,et al. Modification of the ischaemic‐induced contraction in the sheep circumflex coronary artery by various pharmacological antagonists , 1990, British journal of pharmacology.
[824] A. Osuna,et al. Vascular reactivity and flow-pressure curve in isolated kidneys from rats with N-nitro-L-arginine methyl ester-induced hypertension , 1996, Journal of hypertension.
[825] H. Rockman,et al. Role for Thromboxane Receptors in Angiotensin-II–Induced Hypertension , 2004, Hypertension.
[826] P. Reinhart,et al. Molecular Cloning and Characterization of the Intermediate-Conductance Ca2+-Activated K+ Channel in Vascular Smooth Muscle , 1999 .
[827] H. Kwan,et al. TRP channels in endothelial function and dysfunction. , 2007, Biochimica et biophysica acta.
[828] N. Etienne-Selloum,et al. Endothelium-derived contracting factors mediate the Ang II-induced endothelial dysfunction in the rat aorta: preventive effect of red wine polyphenols , 2010, Pflügers Archiv - European Journal of Physiology.
[829] T. Griffith,et al. Nitric oxide-independent relaxations to acetylcholine and A23187 involve different routes of heterocellular communication. Role of Gap junctions and phospholipase A2. , 1999, Circulation research.
[830] S. Taddei,et al. Endothelium‐dependent contractions in hypertension , 2005, British journal of pharmacology.
[831] T. Stevens,et al. Regulation of Endothelial Cell Barrier Function by Store‐Operated Calcium Entry , 2006, Microcirculation.
[832] F. Faraci,et al. Vascular protection: superoxide dismutase isoforms in the vessel wall. , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[833] J. Umans,et al. Effect of pregnancy on mechanisms of relaxation in human omental microvessels. , 1996, Hypertension.
[834] K. Kamata,et al. Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats. , 2004, Canadian journal of physiology and pharmacology.
[835] J. Nishimura,et al. Thapsigargin‐induced endothelium‐dependent triphasic regulation of vascular tone in the porcine renal artery , 1999, British journal of pharmacology.
[836] J. Zweier,et al. Peroxynitrite induces destruction of the tetrahydrobiopterin and heme in endothelial nitric oxide synthase: transition from reversible to irreversible enzyme inhibition. , 2010, Biochemistry.
[837] R. Henning,et al. Altered myogenic constriction and endothelium-derived hyperpolarizing factor-mediated relaxation in small mesenteric arteries of hypertensive subtotally nephrectomized rats , 2006, Journal of hypertension.
[838] J. Imig. Targeting Epoxides for Organ Damage in Hypertension , 2010, Journal of cardiovascular pharmacology.
[839] Brij B. Singh,et al. Assembly of Trp1 in a Signaling Complex Associated with Caveolin-Scaffolding Lipid Raft Domains* , 2000, The Journal of Biological Chemistry.
[840] A. Hodgkin,et al. The effect of sodium ions on the electrical activity of the giant axon of the squid , 1949, The Journal of physiology.
[841] Z. Endre,et al. Renal endothelial dysfunction and impaired autoregulation after ischemia-reperfusion injury result from excess nitric oxide. , 2006, American journal of physiology. Renal physiology.
[842] R. Ordway,et al. Arachidonic acid and other fatty acids directly activate potassium channels in smooth muscle cells. , 1989, Science.
[843] J. Vane,et al. Identification of endothelin 1 and big endothelin 1 in secretory vesicles isolated from bovine aortic endothelial cells. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[844] S. Narumiya,et al. Prostaglandin E2 Induces Vascular Relaxation by E-Prostanoid 4 Receptor-Mediated Activation of Endothelial Nitric Oxide Synthase , 2007, Hypertension.
[845] O. Rådmark. Arachidonate 5-lipoxygenase. , 2002, Journal of lipid mediators and cell signalling.
[846] P. Devillier,et al. Involvement of cysteinyl leukotrienes in angiotensin II-induced contraction in isolated aortas from transgenic (mRen-2)27 rats , 2002, Journal of hypertension.
[847] C. Patrono,et al. Cyclooxygenase-2 Expression and Inhibition in Atherothrombosis , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[848] L. Janssen. Are endothelium-derived hyperpolarizing and contracting factors isoprostanes? , 2002, Trends in pharmacological sciences.
[849] R. Ginnan,et al. Interplay between calcium and reactive oxygen/nitrogen species: an essential paradigm for vascular smooth muscle signaling. , 2010, Antioxidants & redox signaling.
[850] K. Helle,et al. Relaxing effects of cyclic GMP and cyclic AMP-enhancing agents on the long-lasting contraction to endothelin-1 in the porcine coronary artery. , 1998, Scandinavian journal of clinical and laboratory investigation.
[851] S. G. Taylor,et al. Endothelium-derived hyperpolarizing a new endogenous inhibitor from the vascular endothelium , 1988 .
[852] C. DeSouza,et al. Endothelin-1 Vasoconstrictor Tone Increases With Age in Healthy Men But Can Be Reduced by Regular Aerobic Exercise , 2007, Hypertension.
[853] S. Snyder,et al. H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase , 2008, Science.
[854] J. López-Barneo,et al. Reduction of Ca(2+) channel activity by hypoxia in human and porcine coronary myocytes. , 2002, Cardiovascular research.
[855] Kakoli Parai,et al. β-Adrenoceptor mediated responses in rat pulmonary artery: putative role of TASK-1 related K channels , 2006, Naunyn-Schmiedeberg's Archives of Pharmacology.
[856] E. Stankevičius,et al. Combination of Ca2+‐activated K+ channel blockers inhibits acetylcholine‐evoked nitric oxide release in rat superior mesenteric artery , 2006, British journal of pharmacology.
[857] R. Köhler,et al. Prominent role of KCa3.1 in endothelium-derived hyperpolarizing factor-type dilations and conducted responses in the microcirculation in vivo. , 2009, Cardiovascular research.
[858] R. Busse,et al. Endothelium-dependent hyperpolarization of smooth muscle cells in rabbit femoral arteries is not mediated by EDRF (nitric oxide) , 1988, Naunyn-Schmiedeberg's Archives of Pharmacology.
[859] C. de Wit,et al. Distinct Endothelium-Derived Hyperpolarizing Factors Emerge In Vitro and In Vivo and Are Mediated in Part via Connexin 40–Dependent Myoendothelial Coupling , 2011, Hypertension.
[860] Manuela Zaccolo,et al. of in The Role of the in the A Molecular for Generating cAMP and cGMP Signaling Cross-Talk Role of Phosphodiesterases and Implications for Cardiac Pathophysiology , 2007 .
[861] T. Itoh,et al. Effects of H2O2 on membrane potential of smooth muscle cells in rabbit mesenteric resistance artery. , 2003, European Journal of Pharmacology.
[862] H. Wulff,et al. Modulators of small- and intermediate-conductance calcium-activated potassium channels and their therapeutic indications. , 2007, Current medicinal chemistry.
[863] J. Fauchère,et al. NPY receptor subtypes involved in the contraction of the proximal colon of the rat , 1998, Regulatory Peptides.
[864] M. Hecker,et al. Etomidate and Thiopental Inhibit the Release of Endothelium‐derived Hyperpolarizing Factor in the Human Renal Artery , 1996, Anesthesiology.
[865] D. Kass,et al. Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics. , 2009, Pharmacology & therapeutics.
[866] G. Edwards,et al. Endothelium-derived hyperpolarizing factor--a critical appraisal. , 1998, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques.
[867] J. Liao,et al. Inhibition of Vascular Smooth Muscle Cell Migration by Cytochrome P450 Epoxygenase-Derived Eicosanoids , 2002, Circulation research.
[868] J. López-Barneo,et al. Ca2+ channel‐sarcoplasmic reticulum coupling: a mechanism of arterial myocyte contraction without Ca2+ influx , 2003, The EMBO journal.
[869] M. Nelson,et al. Inward rectifier K+ currents in smooth muscle cells from rat resistance-sized cerebral arteries. , 1993, The American journal of physiology.
[870] S. Lundin,et al. Metabolism and excretion of nitric oxide in humans. An experimental and clinical study. , 1993, Circulation research.
[871] K A Dora,et al. Elevation of intracellular calcium in smooth muscle causes endothelial cell generation of NO in arterioles. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[872] G. Burnstock. Release of vasoactive substances from endothelial cells by shear stress and purinergic mechanosensory transduction , 1999, Journal of anatomy.
[873] H. Kaneto,et al. Association of soluble epoxide hydrolase gene polymorphism with insulin resistance in type 2 diabetic patients. , 2005, Biochemical and biophysical research communications.
[874] C. Garland,et al. Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries , 1997, British journal of pharmacology.
[875] Y. Urade,et al. Lipocalin-type and hematopoietic prostaglandin D synthases as a novel example of functional convergence. , 2002, Prostaglandins & other lipid mediators.
[876] L. Ignarro,et al. Association between cyclic GMP accumulation and acetylcholine-elicited relaxation of bovine intrapulmonary artery. , 1984, The Journal of pharmacology and experimental therapeutics.
[877] P. Vanhoutte,et al. Suppression of K+‐induced hyperpolarization by phenylephrine in rat mesenteric artery: relevance to studies of endothelium‐derived hyperpolarizing factor , 2001, British journal of pharmacology.
[878] P. Boor,et al. The Selective TP Receptor Antagonist, S18886 (Terutroban), Attenuates Renal Damage in the Double Transgenic Rat Model of Hypertension , 2007, American Journal of Nephrology.
[879] Wenzheng Zhang,et al. Protein interactions with nitric oxide synthases: controlling the right time, the right place, and the right amount of nitric oxide. , 2003, American journal of physiology. Renal physiology.
[880] K. Komori,et al. Heterogeneous distribution of muscarinic receptors in the rabbit saphenous artery , 1987, British journal of pharmacology.
[881] Youjun Wang,et al. STIM, ORAI AND TRPC CHANNELS IN THE CONTROL OF CALCIUM ENTRY SIGNALS IN SMOOTH MUSCLE , 2008, Clinical and experimental pharmacology & physiology.
[882] J. Keizer,et al. Model of beta-cell mitochondrial calcium handling and electrical activity. II. Mitochondrial variables. , 1998, The American journal of physiology.
[883] Jiqiu Chen,et al. Hypertension Does Not Account for the Accelerated Atherosclerosis and Development of Aneurysms in Male Apolipoprotein E/Endothelial Nitric Oxide Synthase Double Knockout Mice , 2001, Circulation.
[884] B. T. Altura,et al. Hydrogen peroxide-induced endothelium-dependent , 1999 .
[885] Eric F. Johnson,et al. The CYP4A Isoforms Hydroxylate Epoxyeicosatrienoic Acids to Form High Affinity Peroxisome Proliferator-activated Receptor Ligands* , 2002, The Journal of Biological Chemistry.
[886] J. Michel,et al. A fourth isoform of endothelin-converting enzyme (ECE-1) is generated from an additional promoter molecular cloning and characterization. , 1999, European journal of biochemistry.
[887] É. Thorin,et al. The cardiovascular physiology and pharmacology of endothelin-1. , 2010, Advances in pharmacology.
[888] J. Jaggar,et al. Isoform-Selective Physical Coupling of TRPC3 Channels to IP3 Receptors in Smooth Muscle Cells Regulates Arterial Contractility , 2010, Circulation research.
[889] B. Nilius,et al. Role of cytochrome P450-dependent transient receptor potential V4 activation in flow-induced vasodilatation. , 2008, Cardiovascular research.
[890] T. Michel,et al. Cellular signaling and NO production , 2010, Pflügers Archiv - European Journal of Physiology.
[891] E. Seto,et al. Acetylation and deacetylation of non-histone proteins. , 2005, Gene.
[892] Toshio Kitazawa,et al. Cyclic GMP Causes Ca2+ Desensitization in Vascular Smooth Muscle by Activating the Myosin Light Chain Phosphatase* , 1997, The Journal of Biological Chemistry.
[893] J. Pernow,et al. The importance of endothelin-1 for vascular dysfunction in cardiovascular disease. , 2007, Cardiovascular research.
[894] J. Stallone,et al. Sympathy for the devil: the role of thromboxane in the regulation of vascular tone and blood pressure. , 2008, American journal of physiology. Heart and circulatory physiology.
[895] E. Honoré,et al. The neuronal background K2P channels: focus on TREK1 , 2007, Nature Reviews Neuroscience.
[896] T. Rabelink,et al. C-Type Natriuretic Peptide-Induced Vasodilation Is Dependent On Hyperpolarization in Human Forearm Resistance Vessels , 2001, Hypertension.
[897] H. Suzuki,et al. Some electrical properties of the endothelium‐dependent hyperpolarization recorded from rat arterial smooth muscle cells. , 1989, The Journal of physiology.
[898] D. Riendeau,et al. Double-label expression studies of prostacyclin synthase, thromboxane synthase and COX isoforms in normal aortic endothelium. , 2007, Biochimica et biophysica acta.
[899] J. Pfau,et al. Extracellular transsulfuration generates hydrogen sulfide from homocysteine and protects endothelium from redox stress. , 2010, American journal of physiology. Heart and circulatory physiology.
[900] R. Cohen,et al. Elevated glucose promotes generation of endothelium-derived vasoconstrictor prostanoids in rabbit aorta. , 1990, The Journal of clinical investigation.
[901] K. Chandy,et al. The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans. , 2008, The Journal of clinical investigation.
[902] G. He,et al. Hyperkalemia alters endothelium-dependent relaxation through non-nitric oxide and noncyclooxygenase pathway: a mechanism for coronary dysfunction due to cardioplegia. , 1996, The Annals of thoracic surgery.
[903] C. Hill,et al. Attenuation of conducted vasodilatation in rat mesenteric arteries during hypertension: role of inwardly rectifying potassium channels , 2004, The Journal of physiology.
[904] B. Tesfamariam,et al. Dissociation of endothelial cell dysfunction and blood pressure in SHR. , 1995, The American journal of physiology.
[905] Zhanjun Jia,et al. Deletion of Microsomal Prostaglandin E Synthase-1 Increases Sensitivity to Salt Loading and Angiotensin II Infusion , 2006, Circulation research.
[906] H. Miura,et al. Human coronary arteriolar dilation to arachidonic acid depends on cytochrome P-450 monooxygenase and Ca2+-activated K+ channels. , 1998, Circulation research.
[907] R. Andriantsitohaina,et al. Heterogeneity of endothelium-dependent vasorelaxation in conductance and resistance arteries from Lyon normotensive and hypertensive rats , 2003, Journal of hypertension.
[908] K. Kamata,et al. Mechanisms underlying the impaired EDHF-type relaxation response in mesenteric arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats. , 2006, European journal of pharmacology.
[909] M. Schindler,et al. Development and potential of non-peptide antagonists for calcitonin-gene-related peptide (CGRP) receptors: evidence for CGRP receptor heterogeneity. , 2001, Biochemical Society transactions.
[910] P. Libby,et al. Prostaglandin E2 Suppresses Chemokine Production in Human Macrophages through the EP4 Receptor* , 2002, The Journal of Biological Chemistry.
[911] N. Abraham,et al. Arachidonic acid-induced endothelial-dependent relaxations of canine coronary arteries: contribution of a cytochrome P-450-dependent pathway. , 1987, The Journal of pharmacology and experimental therapeutics.
[912] D. Paul,et al. Central Role of Connexin40 in the Propagation of Electrically Activated Vasodilation in Mouse Cremasteric Arterioles In Vivo , 2003, Circulation research.
[913] H. Willard,et al. Molecular cloning of cDNA encoding the Ca2+ release channel (ryanodine receptor) of rabbit cardiac muscle sarcoplasmic reticulum. , 1990, The Journal of biological chemistry.
[914] K. Muraki,et al. Activation of Ca(2+)-dependent K(+) current by nordihydroguaiaretic acid in porcine coronary arterial smooth muscle cells. , 1999, The Journal of pharmacology and experimental therapeutics.
[915] M. Nelson,et al. Extracellular K(+)‐induced hyperpolarizations and dilatations of rat coronary and cerebral arteries involve inward rectifier K(+) channels. , 1996, The Journal of physiology.
[916] P. Vanhoutte,et al. Openers of calcium-activated potassium channels and endothelium-dependent hyperpolarizations in the guinea pig carotid artery , 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.
[917] A. Adeagbo. Endothelium-derived hyperpolarizing factor: characterization as a cytochrome P450 1A-linked metabolite of arachidonic acid in perfused rat mesenteric prearteriolar bed. , 1997, American journal of hypertension.
[918] A. Pries,et al. Impaired Hyperpolarization in Regenerated Endothelium After Balloon Catheter Injury , 2001, Circulation research.
[919] E. Okon,et al. In the presence of L‐NAME SERCA blockade induces endothelium‐dependent contraction of mouse aorta through activation of smooth muscle prostaglandin H2/thromboxane A2 receptors , 2002, British journal of pharmacology.
[920] R. Cohen,et al. Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C. , 1991, The Journal of clinical investigation.
[921] Y. Nakaya,et al. Hydrogen peroxide-induced vascular relaxation in porcine coronary arteries is mediated by Ca2+-activated K+ channels , 2007, Heart and Vessels.
[922] E. Rimm,et al. Acceleration of Cardiovascular Disease by a Dysfunctional Prostacyclin Receptor Mutation: Potential Implications for Cyclooxygenase-2 Inhibition , 2008, Circulation research.
[923] J. Hibbs,et al. L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells. , 1987, Journal of immunology.
[924] S. Narumiya,et al. Roles of Prostaglandin I2 and Thromboxane A2 in Cardiac Ischemia-Reperfusion Injury: A Study Using Mice Lacking Their Respective Receptors , 2001, Circulation.
[925] A. Quyyumi,et al. Endogenous Endothelin in Human Coronary Vascular Function: Differential Contribution of Endothelin Receptor Types A and B , 2007, Hypertension.
[926] P. Pacher,et al. Cannabinoid CB1 receptor inhibition decreases vascular smooth muscle migration and proliferation , 2008, Biochemical and biophysical research communications.
[927] L. Neyses,et al. Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells. , 2010, Cardiovascular research.
[928] G. Garcı́a-Cardeña,et al. Nitric oxide synthase inhibitors attenuate transforming-growth-factor-beta 1-stimulated capillary organization in vitro. , 1997, The American journal of pathology.
[929] N. Flavahan,et al. Natural Course of the Impairment of Endothelium-Dependent Relaxations After Balloon Endothelium Removal in Porcine Coronary Arteries Possible Dysfunction of a Pertussis Toxin-Sensitive G Protein , 1989, Circulation research.
[930] C. Cavadas,et al. Neuropeptide Y expression, localization and cellular transducing effects in HUVEC , 2005, Biology of the cell.
[931] C. Baylis. ACUTE INTERACTIONS BETWEEN ENDOTHELIN AND NITRIC OXIDE IN THE CONTROL OF RENAL HAEMODYNAMICS , 1999, Clinical and experimental pharmacology & physiology.
[932] J. Pernow,et al. Characterization of endothelin-1-induced vascular effects in the rat heart by using endothelin receptor antagonists. , 1994, European journal of pharmacology.
[933] Cuk-Seong Kim,et al. SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase , 2007, Proceedings of the National Academy of Sciences.
[934] S. Moncada,et al. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor , 1987, Nature.
[935] C. Triggle,et al. Catalase has negligible inhibitory effects on endothelium‐dependent relaxations in mouse isolated aorta and small mesenteric artery , 2003, British journal of pharmacology.
[936] J. Vijg,et al. Reduction of pressor response to vasoconstrictor agents by overexpression of catalase in mice. , 2003, American journal of hypertension.
[937] C. Szabó. Hydrogen sulphide and its therapeutic potential , 2007, Nature Reviews Drug Discovery.
[938] M. Blaustein,et al. Distinct Distribution of Different Na+ Pump α Subunit Isoforms in Plasmalemma , 1997 .
[939] W. K. Sonnenburg,et al. Concentrations of prostaglandin endoperoxide synthase and prostaglandin I2 synthase in the endothelium and smooth muscle of bovine aorta. , 1983, The Journal of clinical investigation.
[940] S. yet,et al. Role of Heme Oxygenase-1 in the Regulation of Blood Pressure and Cardiac Function , 2003, Experimental biology and medicine.
[941] J. Sullivan,et al. Potassium channels: molecular defects, diseases, and therapeutic opportunities. , 2000, Pharmacological reviews.
[942] H. Shimokawa. Hydrogen peroxide as an endothelium-derived hyperpolarizing factor , 2010, Pflügers Archiv - European Journal of Physiology.
[943] J. Garthwaite,et al. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain , 1988, Nature.
[944] G. Nguyen. Renin, (pro)renin and receptor: an update. , 2011, Clinical science.
[945] A. Heagerty,et al. Functional evidence of a role for two‐pore domain potassium channels in rat mesenteric and pulmonary arteries , 2004, British journal of pharmacology.
[946] É. Thorin,et al. Endothelin-dependent tone limits acetylcholine-induced dilation of resistance coronary vessels after blockade of NO formation in conscious dogs. , 1998, Hypertension.
[947] M. Kähönen,et al. Mesenteric arterial function in vitro in three models of experimental hypertension , 1996, Journal of hypertension.
[948] E. Ferrannini,et al. Hypertension, insulin resistance, and the metabolic syndrome. , 2004, Endocrinology and metabolism clinics of North America.
[949] Y. Hattori,et al. Alterations in EDHF‐mediated hyperpolarization and relaxation in mesenteric arteries of female rats in long‐term deficiency of oestrogen and during oestrus cycle , 2001, British journal of pharmacology.
[950] I. Morita. Distinct functions of COX-1 and COX-2. , 2002, Prostaglandins & other lipid mediators.
[951] T. H. Grayson,et al. Endothelium-Dependent Vasodilation in Human Mesenteric Artery Is Primarily Mediated by Myoendothelial Gap Junctions Intermediate Conductance Calcium-Activated K+ Channel and Nitric Oxide , 2011, Journal of Pharmacology and Experimental Therapeutics.
[952] S. Snyder,et al. Heme Oxygenase-2 Is Neuroprotective in Cerebral Ischemia , 1999, Molecular medicine.
[953] T. Dalsgaard,et al. Calcium-activated potassium channels – a therapeutic target for modulating nitric oxide in cardiovascular disease? , 2010, Expert opinion on therapeutic targets.
[954] P. Neufer,et al. Independence of Connexin Expression and Vasomotor Conduction from Sympathetic Innervation in Hamster Feed Arteries , 2004, Microcirculation.
[955] L. Juillerat-Jeanneret,et al. Angiotensin II Type 2 Receptor–Mediated Vasodilation in Human Coronary Microarteries , 2004, Circulation.
[956] Kazuki Nakamura,et al. CHARACTERIZATION OF NITRIC OXIDE‐ AND PROSTAGLANDIN‐INDEPENDENT RELAXATION IN RESPONSE TO ACETYLCHOLINE IN RABBIT RENAL ARTERY , 1999, Clinical and experimental pharmacology & physiology.
[957] T. M. Griffith,et al. Enhanced inhibition of the EDHF phenomenon by a phenyl methoxyalaninyl phosphoramidate derivative of dideoxyadenosine , 2004, British journal of pharmacology.
[958] O. Pongs. Regulation of the activity of voltage-gated potassium channels by β subunits , 1995 .
[959] J A Peters,et al. Guide to Receptors and Channels (GRAC), 3rd edition , 2008, British journal of pharmacology.
[960] A. Kitabatake,et al. Evidence against a role of cytochrome P450‐derived arachidonic acid metabolites in endothelium‐dependent hyperpolarization by acetylcholine in rat isolated mesenteric artery , 1997, British journal of pharmacology.
[961] C. Fry,et al. Evidence that inward rectifier K+ channels mediate relaxation by the PGI2 receptor agonist cicaprost via a cyclic AMP-independent mechanism. , 2006, Cardiovascular research.
[962] J. Garthwaite,et al. Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. , 1995, Molecular pharmacology.
[963] Valerie B. O’Donnell,et al. Molecular enzymology of lipoxygenases. , 2010, Archives of biochemistry and biophysics.
[964] C. Hill,et al. Incidence of myoendothelial gap junctions in the proximal and distal mesenteric arteries of the rat is suggestive of a role in endothelium-derived hyperpolarizing factor-mediated responses. , 2000, Circulation research.
[965] B. Horowitz,et al. Regulation of BK(Ca) channels expressed in human embryonic kidney 293 cells by epoxyeicosatrienoic acid. , 2001, Molecular pharmacology.
[966] B. Nilius,et al. Overview: Potassium Channels in Vascular Endothelial Cells , 2001 .
[967] J. Falck,et al. Mechanism of rat mesenteric arterial KATP channel activation by 14,15-epoxyeicosatrienoic acid. , 2006, American journal of physiology. Heart and circulatory physiology.
[968] M. Félétou,et al. Anti-aggregating effect of BAY 58-2667, an activator of soluble guanylyl cyclase. , 2010, Vascular pharmacology.
[969] M. Behrens,et al. SH oxidation coordinates subunits of rat brain ryanodine receptor channels activated by calcium and ATP. , 2003, American journal of physiology. Cell physiology.
[970] N. Nakahata. Thromboxane A2: physiology/pathophysiology, cellular signal transduction and pharmacology. , 2008, Pharmacology & therapeutics.
[971] W. Linz,et al. Angiotensin-converting enzyme inhibition alters nitric oxide and superoxide release in normotensive and hypertensive rats. , 1997, Hypertension.
[972] M. Koide,et al. 20‐Hydroxyeicosatetraenoic acid potentiates stretch‐induced contraction of canine basilar artery via PKCα‐mediated inhibition of KCa channel , 2002, British journal of pharmacology.
[973] Peter Jönsson,et al. Characterization of Endothelium- Dependent Relaxation in Guinea Pig Basilar Artery – Effect of Hypoxia and Role of Cytochrome P450 Mono-Oxygenase , 1998, Journal of Vascular Research.
[974] H. Coleman,et al. Prostacyclin and endothelium-dependent hyperpolarization. , 2004, Pharmacological research.
[975] R. Roman,et al. 20-Hydroxyeicosatetraeonic Acid: A New Target for the Treatment of Hypertension , 2010, Journal of cardiovascular pharmacology.
[976] B. Lévy,et al. Neuronal nitric oxide synthase is expressed in rat vascular smooth muscle cells: activation by angiotensin II in hypertension. , 1998, Circulation research.
[977] M. Asano,et al. Decreased arterial responsiveness to multiple cyclic AMP‐generating receptor agonists in spontaneously hypertensive rats , 1989, British journal of pharmacology.
[978] Malte Kelm,et al. Nitrite Reductase Function of Deoxymyoglobin: Oxygen Sensor and Regulator of Cardiac Energetics and Function , 2007, Circulation research.
[979] G. Lowe. Virchow’s Triad Revisited: Abnormal Flow , 2003, Pathophysiology of Haemostasis and Thrombosis.
[980] S. Earley,et al. Pharmacological inhibition of TRPM4 hyperpolarizes vascular smooth muscle. , 2010, American journal of physiology. Cell physiology.
[981] H. Jongsma,et al. Endothelial-Specific Deletion of Connexin40 Promotes Atherosclerosis by Increasing CD73-Dependent Leukocyte Adhesion , 2010, Circulation.
[982] G. Edwards,et al. Effects of methyl β‐cyclodextrin on EDHF responses in pig and rat arteries; association between SKCa channels and caveolin‐rich domains , 2007, British journal of pharmacology.
[983] M. Fishman,et al. Acetylcholine‐induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice , 1999, British journal of pharmacology.
[984] Cor de Wit,et al. Lack of vascular connexin 40 is associated with hypertension and irregular arteriolar vasomotion. , 2003, Physiological genomics.
[985] M. Fujishima,et al. Age and Hypertension Promote Endothelium‐Dependent Contractions to Acetylcholine in the Aorta of the Rat , 1989, Hypertension.
[986] M. Kye,et al. Small conductance Ca2+-activated K+ channels as targets of CNS drug development. , 2004, Current drug targets. CNS and neurological disorders.
[987] Z. Werb,et al. New functions for the matrix metalloproteinases in cancer progression , 2002, Nature Reviews Cancer.
[988] J. Cusick,et al. Reversal of delayed vasospasm by TS-011 in the dual hemorrhage dog model of subarachnoid hemorrhage. , 2006, AJNR. American journal of neuroradiology.
[989] Carine Michiels,et al. Endothelial cell functions , 2003, Journal of cellular physiology.
[990] M. Suematsu,et al. Interactions of multiple gas-transducing systems: hallmarks and uncertainties of CO, NO, and H2S gas biology. , 2010, Antioxidants & redox signaling.
[991] J. Rossi,et al. Ribozyme-Mediated Inhibition of Rat Leukocyte-Type 12-Lipoxygenase Prevents Intimal Hyperplasia in Balloon-Injured Rat Carotid Arteries , 2001, Circulation.
[992] E. Stevens,et al. Potassium channels: gene family, therapeutic relevance, high-throughput screening technologies and drug discovery. , 2002, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques.
[993] A. Yim,et al. Cellular Electrophysiological and Mechanical Effects of Celsior Solution on Endothelial Function in Resistance Coronary Arteries , 2005, Transplantation.
[994] W. Graier,et al. Histamine induces K+, Ca2+, and Cl- currents in human vascular endothelial cells. Role of ionic currents in stimulation of nitric oxide biosynthesis. , 1994, Circulation research.
[995] F. Rivera,et al. Increased Levels of 12(S)-HETE in Patients With Essential Hypertension , 2001, Hypertension.
[996] T. Slowinski,et al. Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension. , 1997, The Journal of clinical investigation.
[997] G. Raman,et al. Local Delivery of the KCa3.1 Blocker, TRAM-34, Prevents Acute Angioplasty-Induced Coronary Smooth Muscle Phenotypic Modulation and Limits Stenosis , 2008, Arteriosclerosis, thrombosis, and vascular biology.
[998] I. Laher,et al. Superficial buffer barrier function of smooth muscle sarcoplasmic reticulum. , 1995, Trends in pharmacological sciences.
[999] K. Kataoka,et al. Aliskiren prevents cardiovascular complications and pancreatic injury in a mouse model of obesity and type 2 diabetes , 2009, Diabetologia.
[1000] J. Falck,et al. Red blood cells: reservoirs of cis- and trans-epoxyeicosatrienoic acids. , 2005, Prostaglandins & other lipid mediators.
[1001] L. Ghiadoni,et al. Endothelium‐dependent contractions and endothelial dysfunction in human hypertension , 2009, British journal of pharmacology.
[1002] D. Edwards,et al. Hydrogen Peroxide Potentiates the EDHF Phenomenon by Promoting Endothelial Ca2+ Mobilization , 2008, Arteriosclerosis, thrombosis, and vascular biology.
[1003] G. Burnstock,et al. Ultrastructural localization of nitric oxide synthase and endothelin in rat pulmonary artery and vein during postnatal development and ageing , 1996, Cell and Tissue Research.
[1004] Hon-chi Lee,et al. Activation of rat mesenteric arterial KATP channels by 11,12-epoxyeicosatrienoic acid. , 2005, American journal of physiology. Heart and circulatory physiology.
[1005] K. Kamata,et al. Cilostazol improves endothelium-derived hyperpolarizing factor-type relaxation in mesenteric arteries from diabetic rats. , 2005, American journal of physiology. Heart and circulatory physiology.
[1006] A. Daugherty,et al. COX-2 up-regulation and vascular smooth muscle contractile hyperreactivity in spontaneous diabetic db/db mice. , 2005, Cardiovascular research.
[1007] G. Rubanyi,et al. The discovery of endothelin: the power of bioassay and the role of serendipity in the discovery of endothelium-derived vasocative substances. , 2011, Pharmacological research.
[1008] Iain S. Bartlett,et al. Homocellular Conduction Along Endothelium and Smooth Muscle of Arterioles in Hamster Cheek Pouch: Unmasking an NO Wave , 2003, Circulation research.
[1009] J. Ohanian,et al. Evidence in Favor of a Calcium-Sensing Receptor in Arterial Endothelial Cells: Studies With Calindol and Calhex 231 , 2005, Circulation research.
[1010] A. Olschewski. Targeting TASK-1 channels as a therapeutic approach. , 2010, Advances in experimental medicine and biology.
[1011] B. Nilius,et al. The pore of TRP channels: trivial or neglected? , 2003, Cell calcium.
[1012] Hikaru Suzuki,et al. THE EFFECTS OF ACETYLCHOLINE ON THE MEMBRANE AND CONTRACTILE PROPERTIES OF SMOOTH MUSCLE CELLS OF THE RABBIT SUPERIOR MESENTERIC ARTERY , 1978, British journal of pharmacology.
[1013] T. Unger,et al. Novel therapeutic targets for hypertension , 2010, Nature Reviews Cardiology.
[1014] J. Falck,et al. Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart. , 2008, American journal of physiology. Heart and circulatory physiology.
[1015] M. Simionescu,et al. Functional ultrastructure of the vascular endothelium: changes in various pathologies. , 2006, Handbook of experimental pharmacology.
[1016] P. Vanhoutte,et al. A Diffusible Substance(s) Mediates Endothelium-Dependent Contractions in the Aorta of SHR , 2003, Hypertension.
[1017] E. Ferrannini,et al. Effect of insulin on acetylcholine-induced vasodilation in normotensive subjects and patients with essential hypertension. , 1995, Circulation.
[1018] N. Villalba,et al. Altered arachidonic acid metabolism via COX‐1 and COX‐2 contributes to the endothelial dysfunction of penile arteries from obese Zucker rats , 2010, British journal of pharmacology.
[1019] V. Gross,et al. Impaired Endothelium-Derived Hyperpolarizing Factor–Mediated Dilations and Increased Blood Pressure in Mice Deficient of the Intermediate-Conductance Ca2+-Activated K+ Channel , 2006, Circulation research.
[1020] P. Fontana,et al. Intercellular Communication in Atherosclerosis , 2013 .
[1021] Shu-Wha Lin,et al. TXAS-deleted mice exhibit normal thrombopoiesis, defective hemostasis, and resistance to arachidonate-induced death. , 2004, Blood.
[1022] R. Boucher,et al. PKA holoenzyme is functionally coupled to CFTR by AKAPs. , 2000, American journal of physiology. Cell physiology.
[1023] R. Köhler,et al. Crucial importance of the endothelial K+ channel SK3 and connexin40 in arteriolar dilations during skeletal muscle contraction , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[1024] D. Coates,et al. The neprilysin (NEP) family of zinc metalloendopeptidases: Genomics and function , 2001, BioEssays : news and reviews in molecular, cellular and developmental biology.
[1025] K. Ley,et al. Leucocyte-endothelial interactions in health and disease. , 2006, Handbook of experimental pharmacology.
[1026] J. Falck,et al. Two distinct pathways account for EDHF‐dependent dilatation in the gracilis artery of dyslipidaemic hApoB+/+ mice , 2005, British journal of pharmacology.
[1027] T. Meitinger,et al. Genetic Variation in Soluble Epoxide Hydrolase (EPHX2) Is Associated With an Increased Risk of Ischemic Stroke in White Europeans , 2008, Stroke.
[1028] Limei Liu,et al. Bone Morphogenic Protein-4 Impairs Endothelial Function through Oxidative Stress–dependent Cyclooxygenase-2 Upregulation Implications on Hypertension Methods and Results: Impaired Endothelium-dependent Relaxations, Exaggerated Endothelium-dependent Con- Tractions, and Reactive Oxygen Species (ros) P , 2022 .
[1029] Makoto Murakami,et al. Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis. , 2005, Journal of biochemistry and molecular biology.
[1030] Y. Guan,et al. Deficiency in ClC-3 Chloride Channels Prevents Rat Aortic Smooth Muscle Cell Proliferation , 2002, Circulation research.
[1031] D. Webb,et al. Contribution of endogenous generation of endothelin-1 to basal vascular tone , 1994, The Lancet.
[1032] S. Verma,et al. Cyclooxygenase-2 Blockade Does Not Impair Endothelial Vasodilator Function in Healthy Volunteers: Randomized Evaluation of Rofecoxib Versus Naproxen on Endothelium-Dependent Vasodilatation , 2001, Circulation.
[1033] S. Sandow,et al. C-type natriuretic peptide: a new endothelium-derived hyperpolarizing factor? , 2007, Trends in pharmacological sciences.
[1034] G. De Nucci,et al. PHARMACOKINETICS AND PHARMACODYNAMICS OF A NITRIC OXIDE‐RELEASING DERIVATIVE OF ENALAPRIL IN MALE BEAGLES , 2007, Clinical and experimental pharmacology & physiology.
[1035] S. Snyder,et al. Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[1036] A. Pshezhetsky,et al. Serine carboxypeptidases in regulation of vasoconstriction and elastogenesis. , 2009, Trends in cardiovascular medicine.
[1037] G. Burnstock,et al. ATP-stimulated release of ATP by human endothelial cells. , 1996, Journal of cardiovascular pharmacology.
[1038] L. Kaczmarek,et al. hSK4/hIK1, a Calmodulin-binding KCa Channel in Human T Lymphocytes , 1999, The Journal of Biological Chemistry.
[1039] C. N. Gillis,et al. The fate of circulating amines within the pulmonary circulation. , 1982, Annual review of physiology.
[1040] M. Félétou,et al. The anti‐aggregating effect of BAY 41‐2272, a stimulator of soluble guanylyl cyclase, requires the presence of nitric oxide , 2010, British journal of pharmacology.
[1041] I. Fleming,et al. Baseline blood flow and bradykinin-induced vasodilator responses in the human forearm are insensitive to the cytochrome P450 2C9 (CYP2C9) inhibitor sulphaphenazole. , 2003, Clinical science.
[1042] Swati Basu,et al. Nitrite Reductase Activity of Cytochrome c* , 2008, Journal of Biological Chemistry.
[1043] S. Woodman,et al. Microvascular Hyperpermeability in Caveolin-1 (−/−) Knock-out Mice , 2002, The Journal of Biological Chemistry.
[1044] T. Bolton,et al. Endothelial‐dependent relaxant actions of carbachol and substance P in arterial smooth muscle , 1986, British journal of pharmacology.
[1045] A. Simon,et al. Decreased intercellular dye-transfer and downregulation of non-ablated connexins in aortic endothelium deficient in connexin37 or connexin40 , 2003, Journal of Cell Science.
[1046] K. Kamata,et al. Abnormalities of endothelium-dependent responses in mesenteric arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats are improved by chronic treatment with thromboxane A2 synthase inhibitor. , 2009, Atherosclerosis.
[1047] T. Masuko,et al. Hydrogen sulfide inhibits activity of three isoforms of recombinant nitric oxide synthase. , 2007, Toxicology.
[1048] Stephanie E. Wölfle,et al. Intact Endothelium-Dependent Dilation and Conducted Responses in Resistance Vessels of Hypercholesterolemic Mice in vivo , 2005, Journal of Vascular Research.
[1049] M. Nelson,et al. Physiological roles and properties of potassium channels in arterial smooth muscle. , 1995, The American journal of physiology.
[1050] Y. Hattori,et al. Ovariectomy Attenuates Hyperpolarization and Relaxation Mediated by Endothelium-Derived Hyperpolarizing Factor in Female Rat Mesenteric Artery: A Concomitant Decrease in Connexin-43 Expression , 2002, Journal of cardiovascular pharmacology.
[1051] R. Busse,et al. Cytochrome P450 2C9‐derived epoxyeicosatrienoic acids induce angiogenesis via cross‐talk with the epidermal growth factor receptor , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[1052] P. Delmas,et al. Molecular basis of the mammalian pressure-sensitive ion channels: focus on vascular mechanotransduction. , 2008, Progress in biophysics and molecular biology.
[1053] M. Mori,et al. Mechanisms underlying the hydrogen peroxide-induced, endothelium-independent relaxation of the norepinephrine-contraction in guinea-pig aorta. , 2003, European journal of pharmacology.
[1054] R. Busse,et al. EDHF: bringing the concepts together. , 2002, Trends in pharmacological sciences.
[1055] R. Gandley,et al. Moderate Hyperhomocysteinemia Decreases Endothelial-Dependent Vasorelaxation in Pregnant But Not Nonpregnant Mice , 2004, Hypertension.
[1056] T. Michel,et al. Sphingosine-1-phosphate and modulation of vascular tone. , 2009, Cardiovascular research.
[1057] V. Ridger,et al. Recombinant P-selectin glycoprotein ligand-1 directly inhibits leukocyte rolling by all 3 selectins in vivo: complete inhibition of rolling is not required for anti-inflammatory effect. , 2003, Blood.
[1058] R. D. Rudic,et al. Molecular control of nitric oxide synthases in the cardiovascular system. , 1999, Cardiovascular research.
[1059] O. Pechanova,et al. Chronic antioxidant therapy fails to ameliorate hypertension: potential mechanisms behind , 2009, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.
[1060] K. Okumura,et al. Prostaglandin H2 may be the endothelium-derived contracting factor released by acetylcholine in the aorta of the rat. , 1990, Hypertension.
[1061] L. Kaczmarek,et al. hSK4, a member of a novel subfamily of calcium-activated potassium channels. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[1062] D. Larhammar,et al. Molecular evolution of NPY receptor subtypes , 2004, Neuropeptides.
[1063] J. Mitchell,et al. Influence of plasma protein on the potencies of inhibitors of cyclooxygenase‐1 and ‐2 , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[1064] J. McMurray,et al. Endothelium-Derived Hyperpolarizing Factor: Identification and Mechanisms of Action in Human Subcutaneous Resistance Arteries , 2001, Circulation.
[1065] M. Félétou,et al. Endothelium-derived hyperpolarising factors and associated pathways: a synopsis , 2010, Pflügers Archiv - European Journal of Physiology.
[1066] R. Busse,et al. Aged Spontaneously Hypertensive Rats Exhibit a Selective Loss of EDHF-Mediated Relaxation in the Renal Artery , 2003, Hypertension.
[1067] J. Hoyer,et al. Mechanosensitive Ca2+ oscillations and STOC activation in endothelial cells , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[1068] Shenyuan L. Zhang,et al. Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai , 2006, Nature.
[1069] P. Arnaud,et al. Evidence for a basal release of a cytochrome-related endothelium-derived hyperpolarizing factor in the radial artery in humans. , 2006, American journal of physiology. Heart and circulatory physiology.
[1070] A. Cheong,et al. Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation. , 2005, Molecular cell.
[1071] F. Ledda,et al. Roles of Nitric Oxide and Endothelium‐Derived Hyperpolarizing Factor in Vasorelaxant Effect of Acetylcholine as Influenced by Aging and Hypertension , 1995, Journal of cardiovascular pharmacology.
[1072] N. Leitinger,et al. Oxidized Phospholipids Alter Vascular Connexin Expression, Phosphorylation, and Heterocellular Communication , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[1073] M. Rand,et al. Mechanisms of nitric oxide‐independent relaxations induced by carbachol and acetylcholine in rat isolated renal arteries , 2000, British journal of pharmacology.
[1074] W. Graier,et al. ORIGIN AND FUNCTION OF EPOXYEICOSATRIENOIC ACIDS IN VASCULAR ENDOTHELIAL CELLS: MORE THAN JUST ENDOTHELIUM‐DERIVED HYPERPOLARIZING FACTOR? , 1998, Clinical and experimental pharmacology & physiology.
[1075] Mark S Taylor,et al. Altered Expression of Small‐Conductance Ca2+‐Activated K+ (SK3) Channels Modulates Arterial Tone and Blood Pressure , 2003, Circulation research.
[1076] G. Rubanyi,et al. Gender difference in endothelial dysfunction in the aorta of spontaneously hypertensive rats. , 1995, Hypertension.
[1077] D. Gutterman,et al. H2O2 Is the Transferrable Factor Mediating Flow-Induced Dilation in Human Coronary Arterioles , 2011, Circulation research.
[1078] D. Gutterman,et al. Transient Receptor Potential Channel Activation and Endothelium-dependent Dilation in the Systemic Circulation , 2011, Journal of cardiovascular pharmacology.
[1079] Joanne L. Hart,et al. Mechanism of vasorelaxation and role of endogenous hydrogen sulfide production in mouse aorta , 2011, Naunyn-Schmiedeberg's Archives of Pharmacology.
[1080] Mark C. Field,et al. The Mechanism of Oxidative Stress Stabilization of the Thromboxane Receptor in COS-7 Cells* , 2004, Journal of Biological Chemistry.
[1081] D. Fulton,et al. Cytochrome P450‐dependent effects of bradykinin in the rat heart , 1995, British journal of pharmacology.
[1082] A. Briones,et al. Hypertension increases the participation of vasoconstrictor prostanoids from cyclooxygenase-2 in phenylephrine responses , 2005, Journal of hypertension.
[1083] N. Fukagawa,et al. Age-related changes in redox signaling and VSMC function. , 2010, Antioxidants & redox signaling.
[1084] J. Falck,et al. Role of tyrosine kinase and PKC in the vasoconstrictor response to 20-HETE in renal arterioles. , 1999, Hypertension.
[1085] Jianhong Luo,et al. Functional Role of Vanilloid Transient Receptor Potential 4-Canonical Transient Receptor Potential 1 Complex in Flow-Induced Ca2+ Influx , 2010, Arteriosclerosis, thrombosis, and vascular biology.
[1086] S. Narumiya,et al. Roles of thromboxane A2 and prostacyclin in the development of atherosclerosis in apoE-deficient mice , 2004 .
[1087] J. Storm,et al. Elevated Blood Pressure Linked to Primary Hyperaldosteronism and Impaired Vasodilation in BK Channel–Deficient Mice , 2005, Circulation.
[1088] G. Burnstock,et al. Endothelial cells cultured from human umbilical vein release ATP, substance P and acetylcholine in response to increased flow , 1990, Proceedings of the Royal Society of London. Series B: Biological Sciences.
[1089] A. Simon,et al. Vascular abnormalities in mice lacking the endothelial gap junction proteins connexin37 and connexin40. , 2002, Developmental biology.
[1090] M. Suematsu,et al. Role of thromboxane derived from COX‐1 and ‐2 in hepatic microcirculatory dysfunction during endotoxemia in mice , 2004, Hepatology.
[1091] S. Dahlén,et al. Dual COXIB/TP antagonists: a possible new twist in NSAID pharmacology and cardiovascular risk. , 2010, Trends in pharmacological sciences.
[1092] P. Maffia,et al. Time course of vascular reactivity to contracting and relaxing agents after endothelial denudation by balloon angioplasty in rat carotid artery. , 2003, Atherosclerosis.
[1093] L. Puybasset,et al. Coronary and systemic hemodynamic effects of sustained inhibition of nitric oxide synthesis in conscious dogs. Evidence for cross talk between nitric oxide and cyclooxygenase in coronary vessels. , 1996, Circulation research.
[1094] N. Villalba,et al. Enhanced cyclooxygenase 2‐mediated vasodilatation in coronary arteries from insulin resistant obese Zucker rats , 2009, Atherosclerosis.
[1095] M. Bodelsson,et al. Endothelium‐dependent relaxation by substance P in human isolated omental arteries and veins: relative contribution of prostanoids, nitric oxide and hyperpolarization , 1997, British journal of pharmacology.
[1096] Y. Nakaya,et al. Endothelium-derived hyperpolarizing factor activates Ca2+-activated K+ channels in porcine coronary artery smooth muscle cells. , 1998, Journal of cardiovascular pharmacology.
[1097] Tetsuhiro Yamada,et al. 2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304), an Orally Available and Long-Acting Prostacyclin Receptor Agonist Prodrug , 2007, Journal of Pharmacology and Experimental Therapeutics.
[1098] S. Eguchi,et al. The Calcium Store Sensor, STIM1, Reciprocally Controls Orai and CaV1.2 Channels , 2010, Science.
[1099] R. Haddock,et al. Endothelial coordination of cerebral vasomotion via myoendothelial gap junctions containing connexins 37 and 40. , 2006, American journal of physiology. Heart and circulatory physiology.
[1100] C. Triggle,et al. Comparison of the pharmacological properties of EDHF‐mediated vasorelaxation in guinea‐pig cerebral and mesenteric resistance vessels , 2000, British journal of pharmacology.
[1101] P. Vanhoutte,et al. The thromboxane/endoperoxide receptor (TP): the common villain. , 2010, Journal of cardiovascular pharmacology.
[1102] H Shimokawa,et al. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice. , 2000, The Journal of clinical investigation.
[1103] S. Black,et al. S-nitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[1104] J. Bény,et al. Interaction of bradykinin and des-Arg9-bradykinin with isolated pig coronary arteries: mechanical and electrophysiological events , 1987, Regulatory Peptides.
[1105] A. Makino,et al. Mechanisms underlying the attenuation of endothelium‐dependent vasodilatation in the mesenteric arterial bed of the streptozotocin‐induced diabetic rat , 2000, British journal of pharmacology.
[1106] A. Terzic,et al. Molecular Pharmacology of ATP-Sensitive K+Channels: How and Why? , 2001 .
[1107] P. Vanhoutte,et al. Role of gap junctions and EETs in endothelium‐dependent hyperpolarization of porcine coronary artery , 2000, British journal of pharmacology.
[1108] S. Olesen,et al. ATP-dependent closure and reactivation of inward rectifier K+ channels in endothelial cells. , 1993, Circulation research.
[1109] W. Durante. Carbon monoxide and bile pigments: surprising mediators of vascular function , 2002, Vascular medicine.
[1110] Y. Gwack,et al. Orai1 is an essential pore subunit of the CRAC channel , 2006, Nature.
[1111] M. Gawaz,et al. Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse. , 2009, Atherosclerosis.
[1112] H. Eizawa,et al. Purification of nitric oxide synthase from rat macrophages. , 1991, The Journal of biological chemistry.
[1113] T. Griffith,et al. Connexins and gap junctions in the EDHF phenomenon and conducted vasomotor responses , 2010, Pflügers Archiv - European Journal of Physiology.
[1114] R. M. Lee,et al. Hydrogen peroxide induces a greater contraction in mesenteric arteries of spontaneously hypertensive rats through thromboxane A2 production , 2001 .
[1115] T. Lüscher,et al. Endothelium-derived vasoactive factors in hypertension: nitric oxide and endothelin , 1995, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.
[1116] R. Köhler,et al. Endothelial K+ channel lacks the Ca2+ sensitivity‐regulating β subunit , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[1117] P. Zygmunt,et al. Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein , 1996, British journal of pharmacology.
[1118] D. Fitzgerald,et al. Intravascular Thrombosis After Hypoxia-Induced Pulmonary Hypertension: Regulation by Cyclooxygenase-2 , 2004, Circulation.
[1119] C. Searles. Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression. , 2006, American journal of physiology. Cell physiology.
[1120] Chander P Arora,et al. Long-term nitric oxide blockade in the pregnant rat: effects on blood pressure and plasma levels of endothelin-1. , 1996, American journal of obstetrics and gynecology.
[1121] R. Busse,et al. Cytochrome P450 2C9 is involved in flow‐dependent vasodilation of peripheral conduit arteries in healthy subjects and in patients with chronic heart failure , 2007, European journal of heart failure.
[1122] J. Mcgiff,et al. Red blood cells (RBCs), epoxyeicosatrienoic acids (EETs) and adenosine triphosphate (ATP) , 2010, Pharmacological reports : PR.
[1123] R. Sauvé,et al. Effects of Thiol-Modifying Agents on a K(Ca2+) Channel of Intermediate Conductance in Bovine Aortic Endothelial Cells , 1997, The Journal of Membrane Biology.
[1124] E. Jaffe,et al. Synthesis of von Willebrand factor by cultured human endothelial cells. , 1974, Proceedings of the National Academy of Sciences of the United States of America.
[1125] Pimonrat Ketsawatsomkron,et al. Angiotensin II and endothelin-1 augment the vascular complications of diabetes via JAK2 activation. , 2007, American journal of physiology. Heart and circulatory physiology.
[1126] A. M. Lefer,et al. Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia , 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[1127] R. Hammer,et al. Low Blood Pressure in Endothelial Cell–Specific Endothelin 1 Knockout Mice , 2010, Hypertension.
[1128] C. Coletta,et al. Hydrogen Sulfide-Induced Dual Vascular Effect Involves Arachidonic Acid Cascade in Rat Mesenteric Arterial Bed , 2011, Journal of Pharmacology and Experimental Therapeutics.
[1129] O. Moe,et al. OKP cells express the Na-dicarboxylate cotransporter NaDC-1. , 2004, American journal of physiology. Cell physiology.
[1130] V. Hinsbergh. Endothelial Permeability for Macromolecules Mechanistic Aspects of Pathophysiological Modulation , 1997 .
[1131] Hyun Joon Kim,et al. Cellular localization of pituitary adenylate cyclase-activating polypeptide in the rat testis. , 2003, Molecules and cells.
[1132] N. Youhnovski,et al. Specific Nitration at Tyrosine 430 Revealed by High Resolution Mass Spectrometry as Basis for Redox Regulation of Bovine Prostacyclin Synthase* , 2003, The Journal of Biological Chemistry.
[1133] Y. Guan,et al. Silence of ClC‐3 chloride channel inhibits cell proliferation and the cell cycle via G1/S phase arrest in rat basilar arterial smooth muscle cells , 2008, Cell proliferation.
[1134] J. Haefliger,et al. Loss of connexin40 is associated with decreased endothelium-dependent relaxations and eNOS levels in the mouse aorta. , 2010, American journal of physiology. Heart and circulatory physiology.
[1135] J. Falck,et al. Adrenic Acid Metabolites as Endogenous Endothelium-Derived and Zona Glomerulosa-Derived Hyperpolarizing Factors , 2010, Hypertension.
[1136] V. R. Prakash,et al. Essential role of nitric oxide in sepsis-induced impairment of endothelium-derived hyperpolarizing factor-mediated relaxation in rat pulmonary artery. , 2010, European journal of pharmacology.
[1137] G. FitzGerald,et al. Human prostacyclin receptor. , 2002, Vitamins and hormones.
[1138] Yoshitaka Takahashi,et al. Arachidonate 12-lipoxygenases. , 2002, Prostaglandins & other lipid mediators.
[1139] L. Kuo,et al. Estrogen potentiates constrictor prostanoid function in female rat aorta by upregulation of cyclooxygenase-2 and thromboxane pathway expression. , 2008, American journal of physiology. Heart and circulatory physiology.
[1140] D. Barrett,et al. Measurement of vasoactive metabolites (hydroxyeicosatetraenoic and epoxyeicosatrienoic acids) in uterine tissues of normal and compromised human pregnancy , 2010, Journal of hypertension.
[1141] J. Gratton,et al. ET(B) receptor and nitric oxide synthase blockade induce BQ-123-sensitive pressor effects in the rabbit. , 1997, Hypertension.
[1142] M. Kirkham,et al. Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles , 2005, The Journal of cell biology.
[1143] A. Gibson,et al. The developing relationship between receptor‐operated and store‐operated calcium channels in smooth muscle , 2002, British journal of pharmacology.
[1144] M. Rosolowsky,et al. Synthesis of hydroxyeicosatetraenoic (HETEs) and epoxyeicosatrienoic acids (EETs) by cultured bovine coronary artery endothelial cells. , 1996, Biochimica et biophysica acta.
[1145] M. Gladwin,et al. Heme Oxygenase-1 Deficiency Accelerates Formation of Arterial Thrombosis Through Oxidative Damage to the Endothelium, Which Is Rescued by Inhaled Carbon Monoxide , 2007, Circulation research.
[1146] R. Cohen,et al. 15‐Hydroxyeicosatetraenoic Acid and Diabetic Endothelial Dysfunction in Rabbit Aorta , 1995, Journal of cardiovascular pharmacology.
[1147] P. Vanhoutte,et al. Potassium ions and endothelium‐derived hyperpolarizing factor in guinea‐pig carotid and porcine coronary arteries , 1999, British journal of pharmacology.
[1148] O. Pongs,et al. Mice With Disrupted BK Channel &bgr;1 Subunit Gene Feature Abnormal Ca2+ Spark/STOC Coupling and Elevated Blood Pressure , 2000, Circulation research.
[1149] H. Nilsson,et al. Vasomotion: mechanisms and physiological importance. , 2003, Molecular interventions.
[1150] T. V. van Veen,et al. Selective deletion of Connexin 40 in renin-producing cells impairs renal baroreceptor function and is associated with arterial hypertension. , 2010, Kidney international.
[1151] T. Rassaf,et al. Plasma nitrite rather than nitrate reflects regional endothelial nitric oxide synthase activity but lacks intrinsic vasodilator action , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[1152] L. Clapp,et al. Evidence that Ca2+-activated K+ channels play a major role in mediating the vascular effects of iloprost and cicaprost. , 1998, European journal of pharmacology.
[1153] K. Martin,et al. Cardioprotective prostacyclin signaling in vascular smooth muscle. , 2007, Prostaglandins & other lipid mediators.
[1154] P. Vanhoutte,et al. Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture). , 2006, American journal of physiology. Heart and circulatory physiology.
[1155] A. Mügge,et al. Selective cyclo-oxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension , 2003, Journal of hypertension.
[1156] M. Cotter,et al. Chronic vitamin E treatment prevents defective endothelium-dependent relaxation in diabetic rat aorta , 1995, Diabetologia.
[1157] Ying Yu,et al. Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function. , 2006, The Journal of clinical investigation.
[1158] R. Latorre,et al. Large conductance Ca2+-activated K+ (BK) channel: activation by Ca2+ and voltage. , 2006, Biological research.
[1159] H. Coleman,et al. Role for endothelium‐derived hyperpolarizing factor in vascular tone in rat mesenteric and hindlimb circulations in vivo , 2002, The Journal of physiology.
[1160] C. Hill,et al. Myoendothelial Gap Junctions May Provide the Pathway for EDHF in Mouse Mesenteric Artery , 2003, Journal of Vascular Research.
[1161] D. Goeddel,et al. Molecular Biology of the Natriuretic Peptides and Their Receptors , 1992, Circulation.
[1162] P. Carmeliet,et al. Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis. , 1993, The Journal of clinical investigation.
[1163] A. Kitabatake,et al. Thapsigargin‐ and cyclopiazonic acid‐induced endothelium‐dependent hyperpolarization in rat mesenteric artery , 1995, British journal of pharmacology.
[1164] B. Teisseire,et al. Converting enzyme inhibition in isolated porcine resistance artery potentiates bradykinin relaxation. , 1990, European journal of pharmacology.
[1165] T. Tejerina,et al. Relaxant effects of L‐citrulline in rabbit vascular smooth muscle , 1998, British journal of pharmacology.
[1166] M. Oriowo,et al. Cyclo-oxygenase-2, endothelium and aortic reactivity during deoxycorticosterone acetate salt-induced hypertension , 2005, Journal of hypertension.
[1167] D. Demarini,et al. N-((1S)-1-{[4-((2S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Part , 2008, Journal of Pharmacology and Experimental Therapeutics.
[1168] Jiali Gu,et al. The thromboxane receptor antagonist S18886 attenuates renal oxidant stress and proteinuria in diabetic apolipoprotein E-deficient mice. , 2006, Diabetes.
[1169] T. Lüscher,et al. Indirect evidence for release of endothelium-derived relaxing factor in human forearm circulation in vivo. Blunted response in essential hypertension. , 1990, Circulation.
[1170] P. Vanhoutte,et al. Nitric oxide the gatekeeper of endothelial vasomotor control. , 2008, Frontiers in bioscience : a journal and virtual library.
[1171] I. Fleming. Cytochrome P450 epoxygenases as EDHF synthase(s). , 2004, Pharmacological research.
[1172] H. Suzuki,et al. Adrenergic transmissions in the guinea‐pig mesenteric artery and their cholinergic modulations. , 1981, The Journal of physiology.
[1173] S. Nakanishi,et al. Cloning and expression of a cDNA encoding an endothelin receptor , 1990, Nature.
[1174] P. Vanhoutte,et al. Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats , 2008, Acta Pharmacologica Sinica.
[1175] J. Tamargo,et al. Role of Reactive Oxygen Species in Kv Channel Inhibition and Vasoconstriction Induced by TP Receptor Activation in Rat Pulmonary Arteries , 2006, Annals of the New York Academy of Sciences.
[1176] M. Ishikawa,et al. Endothelium‐dependent inhibition of platelet aggregation , 1986, British journal of pharmacology.
[1177] J. de Champlain,et al. Endothelin is a dose-dependent trophic factor and a mitogen in small arteries in vivo. , 2006, Cardiovascular research.
[1178] E. Okon,et al. Paracrine effects of endothelial cells in a diabetic mouse model: capacitative calcium entry stimulated thromboxane release. , 2008, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[1179] J. Parratt,et al. Incubation with endotoxin activates the L-arginine pathway in vascular tissue. , 1990, Biochemical and biophysical research communications.
[1180] M. Paul,et al. The role of endothelin in hypertension , 1998, Current opinion in nephrology and hypertension.
[1181] M. Blaustein,et al. Organization of Ca2+ stores in vascular smooth muscle: functional implications. , 2002, Novartis Foundation symposium.
[1182] P. Ortiz de Montellano,et al. Inhibitors of cytochrome P-450 attenuate the myogenic response of dog renal arcuate arteries. , 1991, Circulation research.
[1183] M J Peach,et al. Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase. , 1992, The Journal of biological chemistry.
[1184] T. Lincoln,et al. Regulation of myosin phosphatase by a specific interaction with cGMP- dependent protein kinase Ialpha. , 1999, Science.
[1185] D. Severson,et al. Vascular dysfunction in type 2 diabetic TallyHo mice: role for an increase in the contribution of PGH2/TxA2 receptor activation and cytochrome p450 products. , 2007, Canadian journal of physiology and pharmacology.
[1186] B. Nilius,et al. Modulation of inwardly rectifying potassium channels in cultured bovine pulmonary artery endothelial cells , 1997, The Journal of physiology.
[1187] C. van Breemen,et al. Potentiation of acetylcholine-induced responses in freshly isolated rabbit aortic endothelial cells. , 1996, Journal of vascular research.
[1188] J. Pepper,et al. Stronger inhibition by nonsteroid anti‐inflammatory drugs of cyclooxygenase‐1 in endothelial cells than platelets offers an explanation for increased risk of thrombotic events , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[1189] Geoffrey Burnstock,et al. Roles of P2‐Purinoceptors in the Cardiovascular System , 1991, Circulation.
[1190] D. Lidington,et al. Nitric oxide specifically reduces the permeability of Cx37‐containing gap junctions to small molecules , 2005, Journal of cellular physiology.
[1191] S. Narumiya,et al. Thromboxane A2 and prostaglandin F2α mediate inflammatory tachycardia , 2005, Nature Medicine.
[1192] C. Fike,et al. Cyclooxygenase-2 and an early stage of chronic hypoxia-induced pulmonary hypertension in newborn pigs. , 2005, Journal of applied physiology.
[1193] G. Tipoe,et al. Endothelium-Dependent Contractions Occur in the Aorta of Wild-Type and COX2−/− Knockout But Not COX1−/− Knockout Mice , 2005, Journal of cardiovascular pharmacology.
[1194] M. Majima,et al. AT2 receptor‐dependent vasodilation is mediated by activation of vascular kinin generation under flow conditions , 2002 .
[1195] J. Voorde,et al. Evidence Against the Involvement of Cytochrome P450 Metabolites in Endothelium‐Dependent Hyperpolarization of the Rat Main Mesenteric Artery , 1997, The Journal of physiology.
[1196] H. Kuhn,et al. Interleukin-13 Upregulates Vasodilatory 15-Lipoxygenase Eicosanoids in Rabbit Aorta , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[1197] N. Abraham,et al. Carbon monoxide of vascular origin attenuates the sensitivity of renal arterial vessels to vasoconstrictors. , 2001, The Journal of clinical investigation.
[1198] W. Campbell,et al. 15-Lipoxygenase metabolites contribute to age-related reduction in acetylcholine-induced hypotension in rabbits. , 2008, American journal of physiology. Heart and circulatory physiology.
[1199] A. Heagerty,et al. Investigation of the role of TASK‐2 channels in rat pulmonary arteries; pharmacological and functional studies following RNA interference procedures , 2006, British journal of pharmacology.
[1200] M. Ujhelyi,et al. EDHF-mediated relaxation is impaired in fructose-fed rats. , 1999, Journal of cardiovascular pharmacology.
[1201] C. Schalkwijk,et al. [Vascular complications in diabetes mellitus: role of endothelial dysfunction]. , 1996, Nederlands tijdschrift voor geneeskunde.
[1202] C. Sigmund,et al. Renal Thrombotic Microangiopathy in a Genetic Model of Hypertension in Mice , 2006, Experimental biology and medicine.
[1203] P. Vanhoutte,et al. Differential effects of prostacyclin and iloprost in the isolated carotid artery of the guinea-pig. , 2001, European journal of pharmacology.
[1204] P. Pratt,et al. 20-HETE relaxes bovine coronary arteries through the release of prostacyclin. , 1998, Hypertension.
[1205] Yongbo Tang,et al. Volume‐regulated chloride channels and cerebral vascular remodelling , 2010, Clinical and experimental pharmacology & physiology.
[1206] K. Node,et al. Activation of Gαs Mediates Induction of Tissue-type Plasminogen Activator Gene Transcription by Epoxyeicosatrienoic Acids* , 2001, The Journal of Biological Chemistry.
[1207] K. Chandy,et al. Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[1208] P. Kovanen,et al. Phospholipase A(2) in vascular disease. , 2001, Circulation research.
[1209] G. Burnstock. Purinergic signalling--an overview. , 2008, Novartis Foundation symposium.
[1210] B. Muller,et al. Nitric Oxide Transport and Storage in the Cardiovascular System , 2002, Annals of the New York Academy of Sciences.
[1211] Takao Shimizu,et al. Roles for cytosolic phospholipase A2α as revealed by gene-targeted mice , 2002 .
[1212] F. Hofmann,et al. Function of cGMP-dependent protein kinases as revealed by gene deletion. , 2006, Physiological reviews.
[1213] M. Mendelsohn. Genomic and nongenomic effects of estrogen in the vasculature. , 2002, The American journal of cardiology.
[1214] R. Busse,et al. Inhibition of Endothelial Nitric Oxide Synthase Activity by Proline-Rich Tyrosine Kinase 2 in Response to Fluid Shear Stress and Insulin , 2008, Circulation research.
[1215] M. Yanagisawa,et al. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[1216] D. Clapham,et al. The G-protein-gated atrial K+ channel IKAch is a heteromultimer of two inwardly rectifying K+-channel proteins , 1995, Nature.
[1217] C. Hiley,et al. Hyperpolarisation of rat mesenteric endothelial cells by ATP-sensitive K(+) channel openers. , 2000, European journal of pharmacology.
[1218] P. Baker,et al. Differential mechanisms of endothelium-dependent vasodilator responses in human myometrial small arteries in normal pregnancy and pre-eclampsia. , 2002, Clinical science.
[1219] W. Seeger,et al. Staphylococcal alpha-toxin provokes coronary vasoconstriction and loss in myocardial contractility in perfused rat hearts: role of thromboxane generation. , 2000, Circulation.
[1220] D. Graham,et al. Cyclooxygenase and thromboxane/prostaglandin receptor contribute to aortic endothelium-dependent dysfunction in aging female spontaneously hypertensive rats. , 2009, Journal of applied physiology.
[1221] J. Wray,et al. Epoxygenases and peroxisome proliferator‐activated receptors in mammalian vascular biology , 2008, Experimental physiology.
[1222] H. Bonkovsky,et al. Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate , 2008, Circulation research.
[1223] W. Large,et al. Characteristics and physiological role of the Ca(2+)-activated Cl- conductance in smooth muscle. , 1996, The American journal of physiology.
[1224] J. Falck,et al. 14,15-Dihydroxy-eicosa-5(Z)-enoic Acid Selectively Inhibits 14,15-Epoxyeicosatrienoic Acid-Induced Relaxations in Bovine Coronary Arteries , 2011, Journal of Pharmacology and Experimental Therapeutics.
[1225] Yasuo Ogasawara,et al. Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats. , 2007, American journal of physiology. Heart and circulatory physiology.
[1226] Lingyun Wu,et al. Sustained Normalization of High Blood Pressure in Spontaneously Hypertensive Rats by Implanted Hemin Pump , 2006, Hypertension.
[1227] R. Busse,et al. Antisense oligonucleotides against cytochrome P450 2C8 attenuate EDHF‐mediated Ca2+ changes and dilation in isolated resistance arteries , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[1228] T. Verbeuren. Experimental models of thrombosis and atherosclerosis. , 2006, Therapie.
[1229] J. Bény,et al. Hydrogen peroxide: an endogenous smooth muscle cell hyperpolarizing factor. , 1991, Biochemical and biophysical research communications.
[1230] J. Stasch,et al. NO-independent, haem-dependent soluble guanylate cyclase stimulators. , 2009, Handbook of experimental pharmacology.
[1231] S. Davidge,et al. Estrogen replacement suppresses a prostaglandin H synthase-dependent vasoconstrictor in rat mesenteric arteries. , 1998, Circulation research.
[1232] Stephen J. Wilson,et al. Activation-dependent stabilization of the human thromboxane receptor: role of reactive oxygen species Published, JLR Papers in Press, January 16, 2009. This work was supported by National Institutes of Health/National Heart Lung and Blood Institute Grant HL-066233 to E.M.S. , 2009, Journal of Lipid Research.
[1233] T. Lüscher,et al. Dysfunctional renal nitric oxide synthase as a determinant of salt-sensitive hypertension: mechanisms of renal artery endothelial dysfunction and role of endothelin for vascular hypertrophy and Glomerulosclerosis. , 2000, Journal of the American Society of Nephrology : JASN.
[1234] A. Coviello,et al. Endothelial dysfunction and improvement of the angiotensin II-reactivity in hypercholesterolemic rabbits: role of cyclooxygenase metabolites. , 2008, European journal of pharmacology.
[1235] J. Turk,et al. Upregulation of intermediate-conductance Ca2+-activated K+ channel (IKCa1) mediates phenotypic modulation of coronary smooth muscle. , 2006, American journal of physiology. Heart and circulatory physiology.
[1236] J. Daut,et al. ATP‐sensitive potassium channels in capillaries isolated from guinea‐pig heart , 2000, The Journal of physiology.
[1237] M. Kähönen,et al. Ramipril therapy improves arterial dilation in experimental hypertension. , 1997, Cardiovascular research.
[1238] Kara F. Held,et al. Exquisite sensitivity to subsecond, picomolar nitric oxide transients conferred on cells by guanylyl cyclase-coupled receptors , 2010, Proceedings of the National Academy of Sciences.
[1239] F. Soubrier,et al. Recent advances in knowledge of the structure and function of the angiotensin I converting enzyme , 1995, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.
[1240] P. Cuevas,et al. Enhanced Thromboxane Receptor-Mediated Responses and Impaired Endothelium-Dependent Relaxation in Human Corpus Cavernosum from Diabetic Impotent Men: Role of Protein Kinase C Activity , 2006, Journal of Pharmacology and Experimental Therapeutics.
[1241] R. M. Lee,et al. Hydrogen peroxide is an endothelium‐dependent contracting factor in rat renal artery , 2005, British journal of pharmacology.
[1242] S. Fazel,et al. Microsomal Prostaglandin E2 Synthase-1 Deletion Leads to Adverse Left Ventricular Remodeling After Myocardial Infarction , 2008, Circulation.
[1243] B. Duling,et al. Dissection of two Cx37-independent conducted vasodilator mechanisms by deletion of Cx40: electrotonic versus regenerative conduction. , 2008, American journal of physiology. Heart and circulatory physiology.
[1244] R. Sprague,et al. 5,6-EET-induced contraction of intralobar pulmonary arteries depends on the activation of Rho-kinase. , 2005, Journal of applied physiology.
[1245] R. Paul,et al. Characterization of a coronary vasoconstrictor produced by cultured endothelial cells. , 1985, The American journal of physiology.
[1246] A. Somlyo,et al. Signal transduction by G‐proteins, Rho‐kinase and protein phosphatase to smooth muscle and non‐muscle myosin II , 2000, The Journal of physiology.
[1247] R. Busse,et al. Proinflammatory mediators chronically downregulate the formation of the endothelium-derived hyperpolarizing factor in arteries via a nitric oxide/cyclic GMP-dependent mechanism. , 1999, Circulation.
[1248] D. Herndon,et al. Thromboxane synthetase inhibition and thromboxane receptor blockade preserve pulmonary and circulatory function in a porcine burn sepsis model. , 1994, Journal of the American College of Surgeons.
[1249] R. Haddock,et al. Obesity Up-Regulates Intermediate Conductance Calcium-Activated Potassium Channels and Myoendothelial Gap Junctions to Maintain Endothelial Vasodilator Function , 2010, Journal of Pharmacology and Experimental Therapeutics.
[1250] R. Haddock,et al. Diet-Induced Obesity Impairs Endothelium-Derived Hyperpolarization via Altered Potassium Channel Signaling Mechanisms , 2011, PloS one.
[1251] M. Yanagisawa,et al. ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1 , 1994, Cell.
[1252] N. Nagahara,et al. Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide. , 2009, Journal of biochemistry.
[1253] A. Weston,et al. Endothelium‐dependent effects of acetylcholine in rat aorta: a comparison with sodium nitroprusside and cromakalim , 1988, British journal of pharmacology.
[1254] D. Gibson,et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. , 1992, Science.
[1255] S. Gardiner,et al. Effects of the non‐peptide, non‐selective endothelin antagonist, bosentan, on regional haemodynamic responses to NG‐monomethyl‐L‐arginine in conscious rats , 1996, British journal of pharmacology.
[1256] N. Weintraub,et al. Relationship of arachidonic acid release to porcine coronary artery relaxation. , 1995, Hypertension.
[1257] P. Vanhoutte,et al. Oxygen‐derived free radicals mediate endothelium‐dependent contractions to acetylcholine in aortas from spontaneously hypertensive rats , 2002, British journal of pharmacology.
[1258] J. Falck,et al. Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. , 2001, Molecular pharmacology.
[1259] D. Ganten,et al. Association and cosegregation of stroke with impaired endothelium-dependent vasorelaxation in stroke prone, spontaneously hypertensive rats. , 1996, The Journal of clinical investigation.
[1260] A. Kitabatake,et al. Alterations in endothelium‐dependent hyperpolarization and relaxation in mesenteric arteries from streptozotocin‐induced diabetic rats , 1997, British journal of pharmacology.
[1261] T. Sasaguri,et al. Fluid Shear Stress Induces Lipocalin-Type Prostaglandin D2 Synthase Expression in Vascular Endothelial Cells , 2000 .
[1262] M. Perretti,et al. Carbon Monoxide-Releasing Molecules Modulate Leukocyte-Endothelial Interactions under Flow , 2007, Journal of Pharmacology and Experimental Therapeutics.
[1263] H. Usui,et al. Possible involvement of endothelial leukotrienes in acetylcholine-induced contraction in rabbit coronary artery. , 1996, Life sciences.
[1264] B. Samuelsson,et al. Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[1265] B. Tan,et al. Reduction of NO- and EDHF-Mediated Vasodilatation in Hypertension: Role of Asymmetric Dimethylarginine , 2007, Clinical and experimental hypertension.
[1266] M. Iglarz,et al. Mechanisms of ET-1-induced Endothelial Dysfunction , 2007, Journal of cardiovascular pharmacology.
[1267] J. Yuan,et al. Downregulation of Connexin40 Is Associated with Coronary Endothelial Cell Dysfunction in Streptozotocin-induced Diabetic Mice Cx-mimetic Peptides 40 Gap27 (srpteknvfiv) and Control Scram , 2022 .
[1268] H. Hashitani,et al. K+ Channels Which Contribute to the Acetylcholine‐Induced Hyperpolarization in Smooth Muscle of the Guinea‐Pig Submucosal Arteriole , 1997, The Journal of physiology.
[1269] C. Carman,et al. A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them , 2004, The Journal of cell biology.
[1270] D. W. Cheung,et al. Calcium Activation of Hyperpolarization Response to Acetylcholine in Coronary Endothelial Cells , 1992, Journal of cardiovascular pharmacology.
[1271] Stephen P. H. Alexander,et al. An endogenous cannabinoid as an endothelium-derived vasorelaxant. , 1996, Biochemical and biophysical research communications.
[1272] B. Nilius,et al. TRP channels and mechanosensory transduction: insights into the arterial myogenic response , 2008, Pflügers Archiv - European Journal of Physiology.
[1273] S. Snyder,et al. Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[1274] R. Foresti,et al. Vasoactive properties of CORM‐3, a novel water‐soluble carbon monoxide‐releasing molecule , 2004, British journal of pharmacology.
[1275] T. B. Paiva,et al. Different mechanism of LPS‐induced vasodilation in resistance and conductance arteries from SHR and normotensive rats , 2002, British journal of pharmacology.
[1276] C. Triggle,et al. Enhanced vascular reactivity of small mesenteric arteries from diabetic mice is associated with enhanced oxidative stress and cyclooxygenase products , 2005, British journal of pharmacology.
[1277] M. Gladwin,et al. Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis , 2006, Nature chemical biology.
[1278] N. Abraham,et al. Rat mesenteric arterial dilator response to 11,12-epoxyeicosatrienoic acid is mediated by activating heme oxygenase. , 2006, American journal of physiology. Heart and circulatory physiology.
[1279] A. Malik,et al. Monohydroxyeicosatetraenoic Acids (5‐HETE and 15‐HETE) Induce Pulmonary Vasoconstriction and Edema , 1988, Circulation research.
[1280] Hikaru Suzuki,et al. Endothelium‐dependent hyperpolarization and intercellular electrical coupling in guinea‐pig mesenteric arterioles , 1999, The Journal of physiology.
[1281] K. Weber,et al. Coupled Calcium and Zinc Dyshomeostasis and Oxidative Stress in Cardiac Myocytes and Mitochondria of Rats With Chronic Aldosteronism , 2009, Journal of Cardiovascular Pharmacology.
[1282] J. Falck,et al. Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries. , 2005, American journal of physiology. Heart and circulatory physiology.
[1283] W. Campbell,et al. Chronic hypoxia enhances 15-lipoxygenase-mediated vasorelaxation in rabbit arteries. , 2009, American journal of physiology. Heart and circulatory physiology.
[1284] M. Polokoff,et al. Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. , 1994, Pharmacological reviews.
[1285] B. Janssen,et al. Reactive oxygen species and small-conductance calcium-dependent potassium channels are key mediators of inflammation-induced hypotension and shock , 2010, Journal of Molecular Medicine.
[1286] C. Garland,et al. Role of heterocellular Gap junctional communication in endothelium-dependent smooth muscle hyperpolarization: inhibition by a connexin-mimetic peptide. , 1999, Biochemical and biophysical research communications.
[1287] P. Vanhoutte,et al. Characterization of endothelium‐dependent relaxations resistant to nitro‐l‐arginine in the porcine coronary artery , 1992, British journal of pharmacology.
[1288] K. Marotti,et al. Development of venous occlusions in mice transgenic for the plasminogen activator inhibitor-1 gene , 1990, Nature.
[1289] J. Falck,et al. Bradykinin‐induced, endothelium‐dependent responses in porcine coronary arteries: involvement of potassium channel activation and epoxyeicosatrienoic acids , 2005, British journal of pharmacology.
[1290] I. Greenwood,et al. Dual modulation of swelling‐activated chloride current by NO and NO donors in rabbit portal vein myocytes , 2000, The Journal of physiology.
[1291] M. Hoenig,et al. Cytochrome P450 Activity and Endothelial Dysfunction in Insulin Resistance , 2000, Journal of Vascular Research.
[1292] C. Loddenkemper,et al. Increased TRPC3 expression in vascular endothelium of patients with malignant hypertension , 2009, Modern Pathology.
[1293] B. Altura,et al. Endothelium-dependent relaxation to hydrogen peroxide in canine basilar artery: a potential new cerebral dilator mechanism , 1998, Brain Research Bulletin.
[1294] R. Furchgott,et al. Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta. , 1985, The Journal of pharmacology and experimental therapeutics.
[1295] A. Kurtz,et al. Connexin40 Is Essential for the Pressure Control of Renin Synthesis and Secretion , 2007, Circulation research.
[1296] S. Narumiya,et al. Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation. , 1996, The Journal of clinical investigation.
[1297] D. Criddle,et al. Effect of niflumic acid on noradrenaline‐induced contractions of the rat aorta , 1996, British journal of pharmacology.
[1298] M. Peach,et al. Role of calcium in endothelium-dependent relaxation of arterial smooth muscle. , 1987, The American journal of cardiology.
[1299] R. Busse,et al. The synthesis of 20-HETE in small porcine coronary arteries antagonizes EDHF-mediated relaxation. , 2005, Cardiovascular research.
[1300] Y. Sugimoto,et al. Prostanoid receptor subtypes. , 2002, Prostaglandins & other lipid mediators.
[1301] Kazuo Kitamura,et al. Adrenomedullin: A Protective Factor for Blood Vessels , 2005, Arteriosclerosis, thrombosis, and vascular biology.
[1302] J. Masferrer,et al. 12(R)-hydroxyicosatetraenoic acid: a cytochrome-P450-dependent arachidonate metabolite that inhibits Na+,K+-ATPase in the cornea. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[1303] T. Neild,et al. Contribution of Active Membrane Processes to Conducted Hyperpolarization in Arterioles of Hamster Cheek Pouch , 2004, Microcirculation.
[1304] S. Brain,et al. Vascular actions of calcitonin gene-related peptide and adrenomedullin. , 2004, Physiological reviews.
[1305] M. Rubart,et al. Relaxation of Arterial Smooth Muscle by Calcium Sparks , 1995, Science.
[1306] P. D'Orléans-Juste,et al. Synthesis and degradation of endothelin-1. , 2003, Canadian journal of physiology and pharmacology.
[1307] Andrew P. Somlyo,et al. Signal transduction and regulation in smooth muscle , 1994, Nature.
[1308] B. Duling,et al. Ca2+ and Inositol 1,4,5-Trisphosphate–Mediated Signaling Across the Myoendothelial Junction , 2007, Circulation research.
[1309] A. Hoger,et al. Molecular cloning and expression of a bovine endothelial inward rectifier potassium channel 1 , 1997 .
[1310] P. Taylor,et al. Prevention by insulin treatment of endothelial dysfunction but not enhanced noradrenaline‐induced contractility in mesenteric resistance arteries from streptozotocin‐induced diabetic rats , 1994, British journal of pharmacology.
[1311] J. Stasch,et al. Pharmacological actions of a novel NO‐independent guanylyl cyclase stimulator, BAY 41‐8543: in vitro studies , 2002, British journal of pharmacology.
[1312] G. Pfitzer,et al. Ca2+-dependent and Ca2+-independent regulation of smooth muscle contraction , 2004, Journal of Muscle Research & Cell Motility.
[1313] T. Lüscher,et al. Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. , 1986, Hypertension.
[1314] P. Vanhoutte,et al. Gene expression changes of prostanoid synthases in endothelial cells and prostanoid receptors in vascular smooth muscle cells caused by aging and hypertension. , 2008, Physiological genomics.
[1315] R. Inoue,et al. Predominant distribution of nifedipine-insensitive, high voltage-activated Ca2+ channels in the terminal mesenteric artery of guinea pig. , 1999, Circulation research.
[1316] M. Félétou,et al. The calcium ionophore A23187 induces endothelium‐dependent contractions in femoral arteries from rats with streptozotocin‐induced diabetes , 2007, British journal of pharmacology.
[1317] J. Mitchell,et al. Not so EEZE: the 'EDHF' antagonist 14, 15 epoxyeicosa-5(Z)-enoic acid has vasodilator properties in mesenteric arteries. , 2004, European journal of pharmacology.
[1318] R. Cohen,et al. Targeting the redox regulation of SERCA in vascular physiology and disease. , 2010, Current opinion in pharmacology.
[1319] V. Ullrich,et al. Molecular cloning of human platelet thromboxane A synthase. , 1991, Biochemical and biophysical research communications.
[1320] O. Griffith,et al. NO in septic shock: good, bad or ugly? Learning from iNOS knockouts. , 1996, Trends in microbiology.
[1321] P. Cuevas,et al. ORIGINAL RESEARCH—BASIC SCIENCE: Enhancement of Both EDHF and NO/cGMP Pathways Is Necessary to Reverse Erectile Dysfunction in Diabetic Rats , 2005 .
[1322] L. Marnett,et al. Prostaglandin endoperoxide synthase: structure and catalysis. , 1991, Biochimica et biophysica acta.
[1323] E. Schiffrin. Vascular endothelin in hypertension. , 2005, Vascular pharmacology.
[1324] G. Taffet,et al. Cerebrovascular responses in mice deficient in the potassium channel, TREK-1. , 2010, American journal of physiology. Regulatory, integrative and comparative physiology.
[1325] Jian-zhong Sheng,et al. Small- and intermediate-conductance Ca2+-activated K+ channels directly control agonist-evoked nitric oxide synthesis in human vascular endothelial cells. , 2007, American journal of physiology. Cell physiology.
[1326] D. Webb,et al. Nitric oxide donor drugs: current status and future trends , 2002, Expert opinion on investigational drugs.
[1327] M. Fujishima,et al. The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation. , 1996, Journal of cardiovascular pharmacology.
[1328] P. Moore,et al. Regulation of vascular nitric oxide in vitro and in vivo; a new role for endogenous hydrogen sulphide? , 2006, British journal of pharmacology.
[1329] J. Saris,et al. Is there a local renin-angiotensin system in the heart? , 1999, Cardiovascular research.
[1330] H. Kosaka,et al. Sex-specific acute effect of estrogen on endothelium-derived contracting factor in the renal artery of hypertensive Dahl rats , 2002, Journal of hypertension.
[1331] P. Vanhoutte,et al. Calcium-independent phospholipase A(2) plays a key role in the endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. , 2010, American journal of physiology. Heart and circulatory physiology.
[1332] P. Vanhoutte,et al. Consequences of reduced production of NO on vascular reactivity of porcine coronary arteries after angioplasty: importance of EDHF , 2002, British journal of pharmacology.
[1333] B. Fakler,et al. Organization and Regulation of Small Conductance Ca2+-activated K+ Channel Multiprotein Complexes , 2007, The Journal of Neuroscience.
[1334] R. Cohen,et al. Nitric oxide inhibits capacitative cation influx in human platelets by promoting sarcoplasmic/endoplasmic reticulum Ca2+-ATPase-dependent refilling of Ca2+ stores. , 1999, Circulation research.
[1335] N. Leblanc,et al. Modulation of ICl(Ca) in vascular smooth muscle cells by oxidizing and cysteine-reactive reagents , 2001, Pflügers Archiv.
[1336] G. He,et al. Impaired endothelium-derived hyperpolarizing factor-mediated relaxation in coronary arteries by cold storage with University of Wisconsin solution. , 1998, The Journal of thoracic and cardiovascular surgery.
[1337] P. Vanhoutte,et al. K+ Channels in Cultured Bovine Retinal Pericytes: Effects of &bgr;‐Adrenergic Stimulation , 2003, Journal of cardiovascular pharmacology.
[1338] L. Ghiadoni,et al. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. , 1998, Circulation.
[1339] Juan Fang,et al. TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress. , 2010, American journal of physiology. Heart and circulatory physiology.
[1340] A. Zeiher,et al. Endothelial Function: Cardiac Events , 2005, Circulation.
[1341] J. Shyy,et al. The antiinflammatory effect of laminar flow: the role of PPARgamma, epoxyeicosatrienoic acids, and soluble epoxide hydrolase. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[1342] B. Yan,et al. Renin–angiotensin–aldosterone system blockade for cardiovascular diseases: current status , 2010, British journal of pharmacology.
[1343] Takashi Saito,et al. Flow-Induced Dilation of Human Coronary Arterioles: Important Role of Ca2+-Activated K+ Channels , 2001, Circulation.
[1344] N. Matsuki,et al. The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide. , 1997, Biochemical and biophysical research communications.
[1345] T. Griffith,et al. The endothelial component of cannabinoid‐induced relaxation in rabbit mesenteric artery depends on gap junctional communication , 1999, The Journal of physiology.
[1346] Bernard Thébaud,et al. O2 Sensing in the Human Ductus Arteriosus: Regulation of Voltage-Gated K+ Channels in Smooth Muscle Cells by a Mitochondrial Redox Sensor , 2002, Circulation research.
[1347] L. Walch,et al. Functional studies of leukotriene receptors in vascular tissues. , 2000, American journal of respiratory and critical care medicine.
[1348] M. Félétou,et al. The calcium channel antagonist S 11568 causes endothelium-dependent relaxation in canine arteries. , 1991, European journal of pharmacology.
[1349] D. Zeldin,et al. Increased CYP2J3 Expression Reduces Insulin Resistance in Fructose-Treated Rats and db/db Mice , 2010, Diabetes.
[1350] K. Okumura,et al. Correlation with blood pressure of the acetylcholine-induced endothelium-derived contracting factor in the rat aorta. , 1992, Hypertension.
[1351] M. Félétou,et al. Magnesium Modulates Endothelial Dysfunction Produced by Elevated Glucose Incubation , 1994, Journal of cardiovascular pharmacology.
[1352] R. Wimalasundera,et al. Effect of tumour necrosis factor‐α and interleukin 1β on endothelium‐dependent relaxation in rat mesenteric resistance arteries in vitro , 2003 .
[1353] D. Andersson,et al. Effects of inhibitors of small‐ and intermediate‐conductance calcium‐activated potassium channels, inwardly‐rectifying potassium channels and Na+/K+ ATPase on EDHF relaxations in the rat hepatic artery , 2000, British journal of pharmacology.
[1354] H. Ehrenreich,et al. Endothelium-dependent relaxation counteracting the contractile action of endothelin-1 is partly due to ETB receptor activation , 1996, Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie.
[1355] F. Edwards,et al. Depolarization evoked by acetylcholine in mesenteric arteries of hypertensive rats attenuates endothelium-dependent hyperpolarizing factor , 2007, Journal of hypertension.
[1356] R. Cohen,et al. TP receptors and oxidative stress hand in hand from endothelial dysfunction to atherosclerosis. , 2010, Advances in pharmacology.
[1357] M. Félétou,et al. Vascular endothelial growth factor and the in vivo increase in plasma extravasation in the hamster cheek pouch , 2001, British journal of pharmacology.
[1358] Lei Xi,et al. eNOS phosphorylation: a pivotal molecular switch in vasodilation and cardioprotection? , 2007, Journal of molecular and cellular cardiology.
[1359] Daniel Jones. End of the line for cannabinoid receptor 1 as an anti-obesity target? , 2008, Nature Reviews Drug Discovery.
[1360] H. Cai. Hydrogen peroxide regulation of endothelial function: origins, mechanisms, and consequences. , 2005, Cardiovascular research.
[1361] E. Werner,et al. Reactive Oxygen Species Mediate Endothelium-Dependent Relaxations in Tetrahydrobiopterin-Deficient Mice , 2001, Arteriosclerosis, thrombosis, and vascular biology.
[1362] N. Buus,et al. Novel approaches to improving endothelium-dependent nitric oxide-mediated vasodilatation , 2009, Pharmacological reports : PR.
[1363] S. Nakanishi,et al. Cloning and expression of cDNA for a human thromboxane A2 receptor , 1991, Nature.
[1364] L. Puybasset,et al. Endothelium-dependent hyperpolarization in isolated arteries taken from animals treated with NO-synthase inhibitors. , 1998, Journal of cardiovascular pharmacology.
[1365] Y. Shibusawa,et al. Alteration in endothelial function and modulation by treatment with pioglitazone in rabbit renal artery from short-term hypercholesterolemia. , 2005, Vascular pharmacology.
[1366] M. Hoenig,et al. Mechanisms of Impaired Endothelial Function Associated with Insulin Resistance , 1998, Journal of cardiovascular pharmacology and therapeutics.
[1367] S. Pfister. Aortic thromboxane receptor deficiency alters vascular reactivity in cholesterol-fed rabbits. , 2006, Atherosclerosis.
[1368] Hanjoong Jo,et al. Compensatory Phosphorylation and Protein-Protein Interactions Revealed by Loss of Function and Gain of Function Mutants of Multiple Serine Phosphorylation Sites in Endothelial Nitric-oxide Synthase* , 2003, The Journal of Biological Chemistry.
[1369] F. Coceani,et al. Interactions between NO, CO and an endothelium‐derived hyperpolarizing factor (EDHF) in maintaining patency of the ductus arteriosus in the mouse , 2007, British journal of pharmacology.
[1370] Catherine B. Chan,et al. Reactive oxygen species and endothelial function in diabetes. , 2010, European journal of pharmacology.
[1371] M. Watkins,et al. Synthesis of 8-epi-prostaglandin F2alpha by human endothelial cells: role of prostaglandin H2 synthase. , 1999, The Biochemical journal.
[1372] A. Ahluwalia,et al. Natriuretic Peptide Receptor-C Regulates Coronary Blood Flow and Prevents Myocardial Ischemia/Reperfusion Injury: Novel Cardioprotective Role for Endothelium-Derived C-Type Natriuretic Peptide , 2004, Circulation.
[1373] Pimonrat Ketsawatsomkron,et al. Does Peroxisome Proliferator-activated Receptor-γ (PPARγ) Protect from Hypertension Directly through Effects in the Vasculature?* , 2010, The Journal of Biological Chemistry.
[1374] E. Schiffrin,et al. Vascular gene expression in mice overexpressing human endothelin-1 targeted to the endothelium. , 2011, Physiological genomics.
[1375] P. Little,et al. Endothelin-1 signalling in vascular smooth muscle: pathways controlling cellular functions associated with atherosclerosis. , 2008, Atherosclerosis.
[1376] H. Kinoshita,et al. The role of oxygen-derived free radicals in augmented relaxations to levcromakalim in the aorta from hypertensive rats. , 2001, Japanese journal of pharmacology.
[1377] O. Yuge,,et al. Inhibitory Effect of High Concentration of Glucose on Relaxations to Activation of ATP-Sensitive K+ Channels in Human Omental Artery , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[1378] M. Nishida,et al. Transient Receptor Potential Channels in Cardiovascular Function and Disease , 2006, Circulation research.
[1379] M. Thompson,et al. Endurance exercise training improves endothelium-dependent relaxation in brachial arteries from hypercholesterolemic male pigs. , 2005, Journal of applied physiology.
[1380] M. Ohyanagi,et al. ENHANCED RELEASE OF ENDOTHELIUM‐DERIVED HYPERPOLARIZING FACTOR IN SMALL CORONARY ARTERIES FROM RATS WITH CONGESTIVE HEART FAILURE , 2005, Clinical and experimental pharmacology & physiology.
[1381] C. Kwan,et al. Evidence for P(2)-purinoceptors contribution in H(2)O(2)-induced contraction of rat aorta in the absence of endothelium. , 2000, Cardiovascular research.
[1382] D. Kaye,et al. L-arginine transporters in cardiovascular disease: a novel therapeutic target. , 2007, Pharmacology & therapeutics.
[1383] O. Carretero,et al. Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure. Role of kinins and angiotensin II type 2 receptors. , 1997, The Journal of clinical investigation.
[1384] I. Grgic,et al. Endothelial Ca2+‐activated K+ channels in normal and impaired EDHF–dilator responses – relevance to cardiovascular pathologies and drug discovery , 2009, British journal of pharmacology.
[1385] É. Rousseau,et al. 20-Hydroxyeicosatetraenoic Acid (20-HETE) Activates Mouse TRPC6 Channels Expressed in HEK293 Cells* , 2003, Journal of Biological Chemistry.
[1386] K. Shinozuka,et al. Nerve and drug-induced release of adenine nucleosides and nucleotides from rabbit aorta. , 1990, The Journal of pharmacology and experimental therapeutics.
[1387] R. Hainsworth,et al. Change in endothelial function in mesenteric arteries of sprague‐dawley rats fed a high salt diet , 2002, The Journal of physiology.
[1388] W. Campbell,et al. Beyond vasodilatation: non-vasomotor roles of epoxyeicosatrienoic acids in the cardiovascular system. , 2007, Trends in pharmacological sciences.
[1389] F. Sekiguchi,et al. Effect of chronic treatment with perindopril on endothelium-dependent relaxation of aorta and carotid artery in SHRSP. , 2000, Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi.
[1390] P. Vanhoutte,et al. Calmodulin antagonists inhibit endothelium‐dependent hyperpolarization in the canine coronary artery , 1992, British journal of pharmacology.
[1391] Q. Chai,et al. Peroxynitrite Inhibits Ca2+-Activated K+ Channel Activity in Smooth Muscle of Human Coronary Arterioles , 2002, Circulation research.
[1392] M. Rodríguez-Martínez,et al. Contractile responses elicited by hydrogen peroxide in aorta from normotensive and hypertensive rats. Endothelial modulation and mechanism involved , 1998, British journal of pharmacology.
[1393] H. Aynedjian,et al. Role of thromboxane in impaired renal vasodilatation response to acetylcholine in hypercholesterolemic rats. , 1992, The Journal of clinical investigation.
[1394] E. Puré,et al. Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis , 2006, Proceedings of the National Academy of Sciences.
[1395] M. Félétou,et al. Roles of the inward-rectifier K+ channel and Na+/K+-ATPase in the hyperpolarization to K+ in rat mesenteric arteries. , 2003 .
[1396] K. Hirata,et al. Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase. , 1998, The Journal of clinical investigation.
[1397] B. Mayer,et al. Enzymatic function of nitric oxide synthases. , 1999, Cardiovascular research.
[1398] L. Marnett,et al. Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism. , 1988, Archives of biochemistry and biophysics.
[1399] S. Narumiya,et al. Prostaglandin E2 Protects the Heart From Ischemia-Reperfusion Injury via Its Receptor Subtype EP4 , 2004, Circulation.
[1400] G. Ahlborg,et al. Nitric oxide-endothelin-1 interaction in humans. , 1997, Journal of applied physiology.
[1401] P. Devillier,et al. Cysteinyl leukotrienes are involved in angiotensin II-induced contraction of aorta from spontaneously hypertensive rats. , 2001, Cardiovascular research.
[1402] M. Cotter,et al. Effects of aldose reductase inhibition on responses of the corpus cavernosum and mesenteric vascular bed of diabetic rats. , 2000, Journal of cardiovascular pharmacology.
[1403] O. Woodman,et al. Enhanced role for the opening of potassium channels in relaxant responses to acetylcholine after myocardial ischaemia and reperfusion in dog coronary arteries , 1999, British journal of pharmacology.
[1404] E. Jaffe,et al. Cell biology of endothelial cells. , 1987, Human pathology.
[1405] I. Nishio,et al. Impaired endothelium-dependent relaxation in mesenteric arteries of reduced renal mass hypertensive rats. , 1999, Scandinavian journal of clinical and laboratory investigation.
[1406] M. Moskowitz,et al. Hypertension in mice lacking the gene for endothelial nitric oxide synthase , 1995, Nature.
[1407] Y. Yamamoto,et al. Blockade by 18β‐glycyrrhetinic acid of intercellular electrical coupling in guinea‐pig arterioles , 1998, The Journal of physiology.
[1408] Klaus Ley,et al. Monocyte-endothelial cell interactions in the development of atherosclerosis. , 2008, Trends in cardiovascular medicine.
[1409] S. Nistri,et al. The ACh‐induced contraction in rat aortas is mediated by the Cys Lt1 receptor via intracellular calcium mobilization in smooth muscle cells , 2003, British journal of pharmacology.
[1410] Bernd Nilius,et al. From TRPs to SOCs, CCEs, and CRACs: consensus and controversies. , 2003, Cell calcium.
[1411] K. Rhodes,et al. Heteromultimer Formation in Native K+Channels , 2001 .
[1412] D. Kass,et al. Tetrahydrobiopterin and Cardiovascular Disease , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[1413] P. Vanhoutte,et al. Chronic Inhibition of Nitric-Oxide Synthase Potentiates Endothelium-Dependent Contractions in the Rat Aorta by Augmenting the Expression of Cyclooxygenase-2 , 2010, Journal of Pharmacology and Experimental Therapeutics.
[1414] J. T. Shepherd,et al. Endothelium-dependent contractions to calcium ionophore A23187, arachidonic acid, and acetylcholine in canine basilar arteries. , 1988, Stroke.
[1415] Y. Ito,et al. Membrane properties of the smooth‐muscle fibres of the guinea‐pig portal vein , 1971, The Journal of physiology.
[1416] J. Stallone,et al. Estrogen potentiates vasopressin-induced contraction of female rat aorta by enhancing cyclooxygenase-2 and thromboxane function. , 2005, American journal of physiology. Heart and circulatory physiology.
[1417] N. Standen,et al. Mechanisms that regulate [Ca2+]i following depolarization in rat systemic arterial smooth muscle cells , 2000, The Journal of physiology.
[1418] S. Sage,et al. Electrical properties of resting and acetylcholine‐stimulated endothelium in intact rat aorta. , 1993, The Journal of physiology.
[1419] Paul M. Vanhoutte,et al. The Human Cardiovascular System: Facts and Concepts , 1979 .
[1420] W. Campbell,et al. Vascular pharmacology of epoxyeicosatrienoic acids. , 2010, Advances in pharmacology.
[1421] R. Natarajan,et al. Evidence for 12-lipoxygenase induction in the vessel wall following balloon injury. , 1999, Cardiovascular research.
[1422] D. Hayoz,et al. Endothelial dysfunction in chronic heart failure. Experimental and clinical studies. , 1994, Arzneimittel-Forschung.
[1423] G. W. Payne,et al. Connexin expression and conducted vasodilation along arteriolar endothelium in mouse skeletal muscle. , 2004, Journal of applied physiology.
[1424] A. Kitabatake,et al. Reciprocal changes in endothelium‐derived hyperpolarizing factor‐ and nitric oxide‐system in the mesenteric artery of adult female rats following ovariectomy , 2005, British journal of pharmacology.
[1425] S. Cordellini. Endothelial dysfunction in DOCA-salt hypertension: possible involvement of prostaglandin endoperoxides. , 1999, General pharmacology.
[1426] C. Turck,et al. Endothelin-converting enzyme-1 degrades internalized somatostatin-14. , 2008, Endocrinology.
[1427] Rui Wang. Signaling pathways for the vascular effects of hydrogen sulfide , 2011, Current opinion in nephrology and hypertension.
[1428] P. Brouckaert,et al. CRITICAL ROLE FOR SMALL AND LARGE CONDUCTANCE CALCIUM-DEPENDENT POTASSIUM CHANNELS IN ENDOTOXEMIA AND TNF TOXICITY , 2007, Shock.
[1429] M. Félétou,et al. NPY receptors as drug targets for the central regulation of body weight. , 2006, CNS & neurological disorders drug targets.
[1430] P. Carmeliet. Angiogenesis in health and disease , 2003, Nature Medicine.
[1431] M. Breschi,et al. Pharmacodynamic hybrids coupling established cardiovascular mechanisms of action with additional nitric oxide releasing properties. , 2009, Current pharmaceutical design.
[1432] P. Vanhoutte,et al. Age-dependent decrease in endothelium-dependent hyperpolarizations to endothelin-3 in the rat mesenteric artery. , 1993, Journal of cardiovascular pharmacology.
[1433] M. Simons,et al. Endothelium as master regulator of organ development and growth. , 2009, Vascular pharmacology.
[1434] S Moncada,et al. The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium. , 1987, Biochemical and biophysical research communications.
[1435] C. Ledent,et al. Inactivation of Adenosine A2A Receptor Attenuates Basal and Angiotensin II-induced ROS Production by Nox2 in Endothelial Cells , 2010, The Journal of Biological Chemistry.
[1436] E. Carafoli,et al. The plasma membrane calcium pump: Recent developments and future perspectives , 1996, Experientia.
[1437] B. Nilius,et al. Membrane potential as a modulator of the free intracellular Ca2+ concentration in agonist-activated endothelial cells. , 1999, General physiology and biophysics.
[1438] M. Gollasch,et al. Uterine Vascular Function in a Transgenic Preeclampsia Rat Model , 2008, Hypertension.
[1439] R. Paul,et al. Hypoxia and alkalinization inhibit endothelium-derived nitric oxide but not endothelium-derived hyperpolarizing factor responses in porcine coronary artery. , 1999, The Journal of pharmacology and experimental therapeutics.
[1440] M. Gollasch,et al. Regulation of spontaneous transient outward potassium currents in human coronary arteries. , 1997, Circulation.
[1441] S. Earley,et al. Endothelium-Dependent Cerebral Artery Dilation Mediated by TRPA1 and Ca2+-Activated K+ Channels , 2009, Circulation research.
[1442] L. Kuo,et al. Activation of Barium-Sensitive Inward Rectifier Potassium Channels Mediates Remote Dilation of Coronary Arterioles , 2001, Circulation.
[1443] R. Berne,et al. Propagated Vasodilation in the Microcirculation of the Hamster Cheek Pouch , 1970, Circulation research.
[1444] J. Pearson,et al. Endothelial cell function and thrombosis. , 1994, Bailliere's best practice & research. Clinical haematology.
[1445] A. Schwab,et al. Regulation of a Calcium-sensitive K+ Channel (cIK1) by Protein Kinase C , 2002, The Journal of Membrane Biology.
[1446] S. Moncada,et al. Antiplatelet properties of a novel, non-NO-based soluble guanylate cyclase activator, BAY 41-2272. , 2003, Vascular pharmacology.
[1447] S. Engeli. Dysregulation of the Endocannabinoid System in Obesity , 2008, Journal of neuroendocrinology.
[1448] R. Dolmetsch,et al. The CRAC Channel Activator STIM1 Binds and Inhibits L-Type Voltage-Gated Calcium Channels , 2010, Science.
[1449] W. Hsueh,et al. Vascular protective effects by activation of nuclear receptor PPARgamma. , 2002, Journal of diabetes and its complications.
[1450] R. Busse,et al. Endothelium-Derived Hyperpolarizing Factor Synthase (Cytochrome P450 2C9) Is a Functionally Significant Source of Reactive Oxygen Species in Coronary Arteries , 2001, Circulation research.
[1451] N. L. Alsip,et al. Influence of oestrous cycle and pregnancy on the reactivity of the rat mesenteric vascular bed. , 2000, Human reproduction.
[1452] S. Tanaka,et al. Endothelium‐derived relaxing, contracting and hyperpolarizing factors of mesenteric arteries of hypertensive and normotensive rats , 1999, British journal of pharmacology.
[1453] C. Thuillez,et al. Contribution of endothelium‐derived hyperpolarizing factors to the regulation of vascular tone in humans , 2008, Fundamental & clinical pharmacology.
[1454] S. Mishra,et al. Atorvastatin Restores the Impaired Vascular Endothelium-dependent Relaxations Mediated by Nitric Oxide and Endothelium-derived Hyperpolarizing Factors but Not Hypotension in Sepsis , 2009, Journal of cardiovascular pharmacology.
[1455] D. Beech,et al. K(+)-induced dilation of a small renal artery: no role for inward rectifier K+ channels. , 1998, Cardiovascular research.
[1456] R. Köhler,et al. Modulation of Ca2+-activated K+ channel in renal artery endothelium in situ by nitric oxide and reactive oxygen species. , 2003, Kidney international.
[1457] P. Vanhoutte,et al. Purinergic endothelium-dependent and -independent contractions in rat aorta. , 1993, Hypertension.
[1458] H. Blom,et al. Endothelium-Derived Hyperpolarizing Factor–Mediated Renal Vasodilatory Response Is Impaired During Acute and Chronic Hyperhomocysteinemia , 2004, Circulation.
[1459] A. Franco‐Cereceda,et al. Neuropeptide Y and Sympathetic Neurotransmission a , 1990, Annals of the New York Academy of Sciences.
[1460] M. Rosen,et al. Connexin‐specific cell‐to‐cell transfer of short interfering RNA by gap junctions , 2005, The Journal of physiology.
[1461] B. Schermer,et al. Inhibition of the production of endothelium‐derived hyperpolarizing factor by cannabinoid receptor agonists , 1999, British journal of pharmacology.
[1462] O. Carretero,et al. Reactive oxygen species: role in the relaxation induced by bradykinin or arachidonic acid via EDHF in isolated porcine coronary arteries. , 1999, Journal of cardiovascular pharmacology.
[1463] L. Vaca,et al. Modulation of cell membrane potential in cultured vascular endothelium. , 1996, The American journal of physiology.
[1464] M. Suematsu,et al. Mechanistic probing of gaseous signal transduction in microcirculation. , 2003, Antioxidants & redox signaling.
[1465] Hisham S. Elbatarny,et al. Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system. , 2003, Molecular pharmacology.
[1466] P. Vanhoutte,et al. The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats. , 2008, Cardiovascular research.
[1467] J. Falck,et al. Biochemical and molecular properties of the cytochrome P450 arachidonic acid monooxygenases. , 2002, Prostaglandins & other lipid mediators.
[1468] H. Dvorak,et al. Reinterpretation of endothelial cell gaps induced by vasoactive mediators in guinea‐fig, mouse and rat: many are transcellular pores , 1997, The Journal of physiology.
[1469] R. Karas,et al. Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure , 2003, Nature Medicine.
[1470] K. Okumura,et al. Nitric oxide-dependent vasodilator mechanism is not impaired by hypertension but is diminished with aging in the rat aorta. , 1999, Journal of cardiovascular pharmacology.
[1471] J. Glowinski,et al. Hydrogen peroxide increases gap junctional communication and induces astrocyte toxicity: Regulation by brain macrophages , 2004, Glia.
[1472] M. Gladwin,et al. Deoxymyoglobin Is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration , 2007, Circulation research.
[1473] S. Nelli,et al. Evaluation of potassium ion as the endothelium‐derived hyperpolarizing factor (EDHF) in the bovine coronary artery , 2003, British journal of pharmacology.
[1474] S. Mochizuki,et al. Renin Inhibitor Aliskiren Improves Impaired Nitric Oxide Bioavailability and Protects Against Atherosclerotic Changes , 2008, Hypertension.
[1475] R. Busse,et al. Activators of potassium channels enhance calcium influx into endothelial cells as a consequence of potassium currents , 1990, Naunyn-Schmiedeberg's Archives of Pharmacology.
[1476] A. Pries,et al. Selective blockade of endothelial Ca2+‐activated small‐ and intermediate‐conductance K+‐channels suppresses EDHF‐mediated vasodilation , 2003, British journal of pharmacology.
[1477] D. Warltier,et al. Transient Receptor Potential Vanilloid Type 4–Deficient Mice Exhibit Impaired Endothelium-Dependent Relaxation Induced by Acetylcholine In Vitro and In Vivo , 2009, Hypertension.
[1478] S. Pfister. Role of Lipoxygenase Metabolites of Arachidonic Acid in Enhanced Pulmonary Artery Contractions of Female Rabbits , 2011, Hypertension.
[1479] J. Bény,et al. Effect of mechanical stimulation, substance P and vasoactive intestinal polypeptide on the electrical and mechanical activities of circular smooth muscles from pig coronary arteries contracted with acetylcholine: role of endothelium. , 1986, Pharmacology.
[1480] H. Wise. Multiple signalling options for prostacyclin. , 2003, Acta pharmacologica Sinica.
[1481] S. Earley,et al. A Dietary Agonist of Transient Receptor Potential Cation Channel V3 Elicits Endothelium-Dependent Vasodilation , 2010, Molecular Pharmacology.
[1482] A. Heidland,et al. Renal Effects of S18886 (Terutroban), a TP Receptor Antagonist, in an Experimental Model of Type 2 Diabetes , 2007, Diabetes.
[1483] M. Fujishima,et al. Decreased endothelium-dependent hyperpolarization to acetylcholine in smooth muscle of the mesenteric artery of spontaneously hypertensive rats. , 1992, Circulation research.
[1484] V. Klauss,et al. A sulfaphenazole-sensitive EDHF opposes platelet-endothelium interactions in vitro and in the hamster microcirculation in vivo. , 2010, Cardiovascular research.
[1485] J. Falck,et al. Inhibition of Cytochrome P450&ohgr;-Hydroxylase: A Novel Endogenous Cardioprotective Pathway , 2004, Circulation research.
[1486] M. Randall. Endocannabinoids and the haematological system , 2007, British journal of pharmacology.
[1487] G. Pelle,et al. Improved endothelial function by the thromboxane A2 receptor antagonist S 18886 in patients with coronary artery disease treated with aspirin. , 2003, Journal of the American College of Cardiology.
[1488] D. Jacques,et al. Neuropeptide Y (NPY) and NPY receptors in the cardiovascular system: implication in the regulation of intracellular calcium. , 2007, Canadian journal of physiology and pharmacology.
[1489] H. Kuriyama,et al. ELECTRICAL PROPERTIES OF SMOOTH MUSCLE CELL MEMBRANE AND NEUROMUSCULAR TRANSMISSION IN THE GUINEA‐PIG BASILAR ARTERY , 1981, British journal of pharmacology.
[1490] L. Ruilope,et al. Effects of antihypertensive therapy on factors mediating endothelium-dependent relaxation in rats treated chronically with L-NAME. , 1999, Journal of hypertension.
[1491] L. Li,et al. Acetylcholine-sensitive intracellular Ca2+ store in fresh endothelial cells and evidence for ryanodine receptors. , 1995, Circulation research.
[1492] J. Blanco-Rivero,et al. Participation of Prostacyclin in Endothelial Dysfunction Induced by Aldosterone in Normotensive and Hypertensive Rats , 2005, Hypertension.
[1493] G. Burnstock,et al. Nitric oxide and endothelin-1 in coronary and pulmonary circulation. , 1999, International review of cytology.
[1494] P. Vanhoutte,et al. Nitric Oxide and Inactivation of the Endothelium-Dependent Contracting Factor Released by Acetylcholine in Spontaneously Hypertensive Rat , 2004, Journal of cardiovascular pharmacology.
[1495] H. Ehrenreich,et al. Endothelium-dependent relaxation counteracting the contractile action of endothelin-1 is partly due to ET , 1997 .
[1496] S. Faure,et al. Reactive Oxygen Species and Cyclooxygenase 2–Derived Thromboxane A2 Reduce Angiotensin II Type 2 Receptor Vasorelaxation in Diabetic Rat Resistance Arteries , 2010, Hypertension.
[1497] S. Nigam,et al. 15‐Lipoxygenation of phospholipids may precede the sn‐2 cleavage by phospholipases A2: reaction specificities of secretory and cytosolic phospholipases A2 towards native and 15‐lipoxygenated arachidonoyl phospholipids , 1998, FEBS letters.
[1498] P. Vanhoutte,et al. Characterization of an apamin‐sensitive small‐conductance Ca2+‐activated K+ channel in porcine coronary artery endothelium: relevance to EDHF , 2002, British journal of pharmacology.
[1499] D. Webb,et al. Deletion of Endothelial Cell Endothelin B Receptors Does Not Affect Blood Pressure or Sensitivity to Salt , 2006, Hypertension.
[1500] M. Marletta,et al. Induction of nitrite/nitrate synthesis in murine macrophages by BCG infection, lymphokines, or interferon-gamma. , 1987, Journal of immunology.
[1501] S. Jern,et al. Effects of shear stress on eicosanoid gene expression and metabolite production in vascular endothelium as studied in a novel biomechanical perfusion model. , 2000, Biochemical and biophysical research communications.
[1502] H. Coleman,et al. K+ currents underlying the action of endothelium‐derived hyperpolarizing factor in guinea‐pig, rat and human blood vessels , 2001, The Journal of physiology.
[1503] L. Bendhack,et al. Relaxation Induced by Acetylcholine Involves Endothelium-Derived Hyperpolarizing Factor in 2-Kidney 1-Clip Hypertensive Rat Carotid Arteries , 2004, Pharmacology.
[1504] C. Giannarelli,et al. Cyclooxygenase-1 Is Involved in Endothelial Dysfunction of Mesenteric Small Arteries From Angiotensin II-Infused Mice , 2007, Hypertension.
[1505] William C. Aird,et al. Phenotypic Heterogeneity of the Endothelium: I. Structure, Function, and Mechanisms , 2007, Circulation research.
[1506] A. Ahluwalia,et al. Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[1507] Lei Zhao,et al. Regulation of Thromboxane Receptor Trafficking Through the Prostacyclin Receptor in Vascular Smooth Muscle Cells: Role of Receptor Heterodimerization , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[1508] H. Kuriyama,et al. Effects of acetylcholine on the smooth muscle cell of isolated main coronary artery of the guinea‐pig. , 1979, The Journal of physiology.
[1509] M. Yoder,et al. Is endothelium the origin of endothelial progenitor cells? , 2010, Arteriosclerosis, thrombosis, and vascular biology.
[1510] L. Muller,et al. Endothelin-converting enzyme 1 degrades neuropeptides in endosomes to control receptor recycling , 2007, Proceedings of the National Academy of Sciences.
[1511] Jia Jia Lim,et al. Vasoconstrictive effect of hydrogen sulfide involves downregulation of cAMP in vascular smooth muscle cells. , 2008, American journal of physiology. Cell physiology.
[1512] S. Suh,et al. Globotriaosylceramide leads to K(Ca)3.1 channel dysfunction: a new insight into endothelial dysfunction in Fabry disease. , 2011, Cardiovascular research.
[1513] P. Vanhoutte,et al. K+‐induced hyperpolarization in rat mesenteric artery: identification, localization and role of Na+/K+‐ATPases , 2002, British journal of pharmacology.
[1514] D. Strøbæk,et al. The Ca2+-activated K+ channel of intermediate conductance: a molecular target for novel treatments? , 2001, Current drug targets.
[1515] S. Davidge. Prostaglandin H synthase and vascular function. , 2001, Circulation research.
[1516] B. Fisslthaler,et al. Angiotensin II impairs endothelial function via tyrosine phosphorylation of the endothelial nitric oxide synthase , 2009, The Journal of experimental medicine.
[1517] K.,et al. The Vasorelaxation of Cerebral Arteries by Carbon Monoxide , 2001, Experimental biology and medicine.
[1518] T. Bolton,et al. The diverse effects of noradrenaline and other stimulants on 86Rb and 42K efflux in rabbit and guinea‐pig arterial muscle. , 1984, The Journal of physiology.
[1519] P. Zygmunt,et al. Characterization of the potassium channels involved in EDHF‐mediated relaxation in cerebral arteries , 1997, British journal of pharmacology.
[1520] K. Okumura,et al. Role of Prostaglandin H2 as an Endothelium-Derived Contracting Factor in Diabetic State , 1993, Diabetes.
[1521] R. Touyz,et al. Molecular mechanisms of hypertension: role of Nox family NADPH oxidases. , 2009, Current opinion in nephrology and hypertension.
[1522] N. Brown,et al. Blood pressure reduction and tissue-type plasminogen activator release. , 2006, Hypertension.
[1523] Y. Matsumura,et al. Effects of endogenous and exogenous nitric oxide on endothelin-1 production in cultured vascular endothelial cells. , 1999, European journal of pharmacology.
[1524] B. Mayer,et al. The enigma of nitroglycerin bioactivation and nitrate tolerance: news, views and troubles , 2008, British journal of pharmacology.
[1525] P. Vanhoutte,et al. Alteration of endothelium-dependent hyperpolarizations in porcine coronary arteries with regenerated endothelium. , 1999, Circulation research.
[1526] W. Holland,et al. Role of the cell membrane and mitochondria in the phenomenon of ion transport in cardiac muscle. , 1954, The American journal of physiology.
[1527] W. Klaus,et al. Dual Mode of Action of Dihydropyridine Calcium Antagonists , 1999, Drugs.
[1528] Jin Han,et al. Physiological role of inward rectifier K+ channels in vascular smooth muscle cells , 2008, Pflügers Archiv - European Journal of Physiology.
[1529] C. Sigmund,et al. Impaired endothelial function in transgenic mice expressing both human renin and human angiotensinogen. , 2000, Stroke.
[1530] J. Scuvée-Moreau,et al. Modulation of small conductance calcium-activated potassium (SK) channels: a new challenge in medicinal chemistry. , 2003, Current medicinal chemistry.
[1531] H. S. Bennett,et al. Morphological classifications of vertebrate blood capillaries. , 1959, The American journal of physiology.
[1532] J. Adelman,et al. Genetic Deficit of SK3 and IK1 Channels Disrupts the Endothelium-Derived Hyperpolarizing Factor Vasodilator Pathway and Causes Hypertension , 2009, Circulation.
[1533] T. Bolton,et al. Identification of interstitial cells of Cajal in the rabbit portal vein. , 2003 .
[1534] E. Davidson,et al. Progression of coronary and mesenteric vascular dysfunction in Zucker obese and Zucker diabetic fatty rats. , 2006, American journal of physiology. Heart and circulatory physiology.
[1535] A. M. Lefer,et al. Potent constriction of cat coronary arteries by hydroperoxides of arachidonic acid and its blockade by anti-inflammatory agents. , 1979, Prostaglandins.
[1536] H. Nilsson,et al. Analysis of effects of connexin-mimetic peptides in rat mesenteric small arteries. , 2006, American journal of physiology. Heart and circulatory physiology.
[1537] T. Bolton,et al. Mechanisms of action of noradrenaline and carbachol on smooth muscle of guinea‐pig anterior mesenteric artery. , 1984, The Journal of physiology.
[1538] J. Vane,et al. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[1539] J. McCord,et al. Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice. , 2005, Free radical biology & medicine.
[1540] Rui Wang. Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter? , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[1541] Cuk-Seong Kim,et al. Histone Deacetylase 3 Antagonizes Aspirin-Stimulated Endothelial Nitric Oxide Production by Reversing Aspirin-Induced Lysine Acetylation of Endothelial Nitric Oxide Synthase , 2010, Circulation research.
[1542] N. Minamino,et al. Production and secretion of adrenomedullin from vascular smooth muscle cells: augmented production by tumor necrosis factor-alpha. , 1994, Biochemical and biophysical research communications.
[1543] T. Grosser,et al. Role of Prostacyclin in the Cardiovascular Response to Thromboxane A2 , 2002, Science.
[1544] S. Abramson,et al. Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases. , 2006, Clinical immunology.
[1545] M. Rodríguez-Martínez,et al. Oxidative stress induced by tert-butyl hydroperoxide causes vasoconstriction in the aorta from hypertensive and aged rats: role of cyclooxygenase-2 isoform. , 2000, The Journal of pharmacology and experimental therapeutics.
[1546] S. Earley,et al. Transient receptor potential channels and vascular function. , 2010, Clinical science.
[1547] S. Patel,et al. Molecular properties of inositol 1,4,5-trisphosphate receptors. , 1999, Cell calcium.
[1548] H. Shimokawa,et al. Roles of Endothelial Oxidases in Endothelium-derived Hyperpolarizing Factor Responses in Mice , 2008, Journal of cardiovascular pharmacology.
[1549] R. Roman,et al. Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular system. , 2005, Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi.
[1550] J. Falck,et al. 20-Hydroxyeicosatetraenoic acid is a potent dilator of mouse basilar artery: role of cyclooxygenase. , 2006, American journal of physiology. Heart and circulatory physiology.
[1551] M. Drab,et al. Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice , 2001, Science.
[1552] D. Edwards,et al. Ascorbic acid and tetrahydrobiopterin potentiate the EDHF phenomenon by generating hydrogen peroxide , 2009, Cardiovascular research.
[1553] C. Peers,et al. Hemoxygenase-2 Is an Oxygen Sensor for a Calcium-Sensitive Potassium Channel , 2004, Science.
[1554] C. Lingle,et al. Multiple regulatory sites in large-conductance calcium-activated potassium channels , 2002, Nature.
[1555] T. Hidaka,et al. Thromboxane A2 receptor blockade suppresses intercellular adhesion molecule-1 expression by stimulated vascular endothelial cells. , 1996, European journal of pharmacology.
[1556] The role of the kidney in hypertension. , 1996, JAMA.
[1557] David John Adams,et al. Role of Calcium in the Activation of Endothelial Cells , 1988, Journal of cardiovascular pharmacology.
[1558] A. Porsius,et al. Effects of hypercholesterolemia on the contractions to angiotensin II in the isolated aorta and iliac artery of the rabbit: role of arachidonic acid metabolites. , 1997, Journal of cardiovascular pharmacology.
[1559] S. Archer,et al. Endothelium-Derived Hyperpolarizing Factor in Human Internal Mammary Artery Is 11,12-Epoxyeicosatrienoic Acid and Causes Relaxation by Activating Smooth Muscle BKCa Channels , 2003, Circulation.
[1560] Qin Yang,et al. Use of intermediate/small conductance calcium-activated potassium-channel activator for endothelial protection. , 2011, The Journal of thoracic and cardiovascular surgery.
[1561] R. Busse,et al. The coronary endothelium-derived hyperpolarizing factor (EDHF) stimulates multiple signalling pathways and proliferation in vascular cells , 2001, Pflügers Archiv.
[1562] M. Murthy,et al. Phospholipase A2 activation in human neutrophils requires influx of extracellular Ca2+ and leukotriene B4. , 1995, The American journal of physiology.
[1563] A. Ahluwalia,et al. Definitive role for natriuretic peptide receptor-C in mediating the vasorelaxant activity of C-type natriuretic peptide and endothelium-derived hyperpolarising factor. , 2007, Cardiovascular research.
[1564] F. Murad,et al. Agonist‐Induced Endothelium‐Dependent Relaxation in Rat Thoracic Aorta May Be Mediated through cGMP , 1983, Circulation research.
[1565] P. Vanhoutte,et al. Specific Potentiation of Endothelium-Dependent Contractions in SHR by Tetrahydrobiopterin , 2003, Hypertension.
[1566] K. Chandy,et al. Delineation of the Clotrimazole/TRAM-34 Binding Site on the Intermediate Conductance Calcium-activated Potassium Channel, IKCa1* , 2001, The Journal of Biological Chemistry.
[1567] A. Ahluwalia,et al. Protease-Activated Receptor-2 Activation Causes EDHF-Like Coronary Vasodilation: Selective Preservation in Ischemia/Reperfusion Injury: Involvement of Lipoxygenase Products, VR1 Receptors, and C-Fibers , 2002, Circulation research.
[1568] D. Kendall,et al. Cannabinoid modulation of sensory neurotransmission via cannabinoid and vanilloid receptors: roles in regulation of cardiovascular function. , 2002, Life sciences.
[1569] Mark S Taylor,et al. Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections , 2008, Proceedings of the National Academy of Sciences.
[1570] S. Gupte,et al. Peroxide generation by p47phox-Src activation of Nox2 has a key role in protein kinase C-induced arterial smooth muscle contraction. , 2009, American journal of physiology. Heart and circulatory physiology.
[1571] J. Stamler,et al. S-Nitrosylation in Cardiovascular Signaling , 2010, Circulation research.
[1572] L. Muller,et al. Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and β-arrestins , 2007, The Journal of cell biology.
[1573] B. Levine,et al. Endothelin and aged blood vessels: one more reason to get off the couch? , 2007, Hypertension.
[1574] M. Eberlin,et al. Increased endothelin‐1 reactivity and endothelial dysfunction in carotid arteries from rats with hyperhomocysteinemia , 2009, British journal of pharmacology.
[1575] A. Srivastava,et al. Nitric oxide attenuates endothelin-1-induced activation of ERK1/2, PKB, and Pyk2 in vascular smooth muscle cells by a cGMP-dependent pathway. , 2007, American journal of physiology. Heart and circulatory physiology.