Roles of hepatocyte growth factor (HGF) activator and HGF activator inhibitor in the pericellular activation of HGF/scatter factor
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[1] H. Itoh,et al. Expression of Hepatocyte Growth Factor Activator Inhibitor Type 2 (HAI-2) in Human Testis: Identification of a Distinct Transcription Start Site for the HAI-2 Gene in Testis , 2002, Biological chemistry.
[2] M. Takigawa,et al. CD44 stimulation by fragmented hyaluronic acid induces upregulation and tyrosine phosphorylation of c-Met receptor protein in human chondrosarcoma cells. , 2002, Biochimica et biophysica acta.
[3] S. Wahl,et al. Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis , 2002, Oncogene.
[4] G. Merlino,et al. Constitutive c-Met signaling through a nonautocrine mechanism promotes metastasis in a transgenic transplantation model. , 2002, Cancer research.
[5] S. Nakahara,et al. Prometastatic Effect ofN-Acetylglucosaminyltransferase V Is Due to Modification and Stabilization of Active Matriptase by Adding β1–6 GlcNAc Branching* , 2002, The Journal of Biological Chemistry.
[6] K. Miyazawa,et al. Functional Characterization of Kunitz Domains in Hepatocyte Growth Factor Activator Inhibitor Type 1* , 2002, The Journal of Biological Chemistry.
[7] Baljit Singh,et al. Expression of the serine protease matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: correlation with clinical outcome and tumor clinicopathological parameters. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.
[8] B. Zbar,et al. Dysregulation of Met receptor tyrosine kinase activity in invasive tumors. , 2002, The Journal of clinical investigation.
[9] H. Itoh,et al. Emerging multifunctional aspects of cellular serine proteinase inhibitors in tumor progression and tissue regeneration , 2002, Pathology international.
[10] N. Kitamura,et al. Mouse hepatocyte growth factor (HGF) activator inhibitor type 2 lacking the first Kunitz domain potently inhibits the HGF activator. , 2002, Biochemical and biophysical research communications.
[11] S. Hirono,et al. Expression of hepatocyte growth factor activator and hepatocyte growth factor activator inhibitor type 1 in human hepatocellular carcinoma. , 2001, Biochemical and biophysical research communications.
[12] T. Iwanaga,et al. A role for membrane-type serine protease (MT-SP1) in intestinal epithelial turnover. , 2001, Biochemical and biophysical research communications.
[13] W. Jiang,et al. Expression of hepatocyte growth factor/scatter factor, its activator, inhibitors and the c-Met receptor in human cancer cells. , 2001, International journal of oncology.
[14] H. Itoh,et al. Reduced expression of hepatocyte growth factor activator inhibitor type‐2/placental bikunin (HAI‐2/PB) in human glioblastomas: Implication for anti‐invasive role of HAI‐2/PB in glioblastoma cells , 2001, International journal of cancer.
[15] U. Scherf,et al. Identification of differentially expressed genes in hepatocellular carcinoma and metastatic liver tumors by oligonucleotide expression profiling , 2001, Cancer.
[16] Paul Scherz,et al. Functional analysis of secreted and transmembrane proteins critical to mouse development , 2001, Nature Genetics.
[17] N. Kitamura,et al. Mouse hepatocyte growth factor activator inhibitor type 1 (HAI-1) and type 2 (HAI-2)/placental bikunin genes and their promoters. , 2001, Biochimica et biophysica acta.
[18] J. Barasch,et al. Activation of Hepatocyte Growth Factor (HGF) by Endogenous HGF Activator Is Required for Metanephric Kidney Morphogenesis in Vitro * , 2001, The Journal of Biological Chemistry.
[19] R. Dickson,et al. Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo. , 2001, The American journal of pathology.
[20] R. Dickson,et al. Regulation of the activity of matriptase on epithelial cell surfaces by a blood-derived factor. , 2001, European journal of biochemistry.
[21] H. Itoh,et al. Pericellular activation of hepatocyte growth factor/scatter factor (HGF/SF) in colorectal carcinomas: roles of HGF activator (HGFA) and HGFA inhibitor type 1 (HAI-1). , 2001, Human cell.
[22] K. Miyazawa,et al. Hepatocyte Growth Factor Activator Inhibitor Type 1 Is a Specific Cell Surface Binding Protein of Hepatocyte Growth Factor Activator (HGFA) and Regulates HGFA Activity in the Pericellular Microenvironment* , 2000, The Journal of Biological Chemistry.
[23] H. Itoh,et al. Localization of hepatocyte growth factor activator inhibitor type 1 in Langhans' cells of human placenta , 2000, Histochemistry and Cell Biology.
[24] R. Dickson,et al. Activation of Hepatocyte Growth Factor and Urokinase/Plasminogen Activator by Matriptase, an Epithelial Membrane Serine Protease* , 2000, The Journal of Biological Chemistry.
[25] N. Kitamura,et al. Activation of hepatocyte growth factor/scatter factor in colorectal carcinoma. , 2000, Cancer research.
[26] Jennifer L. Harris,et al. Cellular Localization of Membrane-type Serine Protease 1 and Identification of Protease-activated Receptor-2 and Single-chain Urokinase-type Plasminogen Activator as Substrates* , 2000, The Journal of Biological Chemistry.
[27] N. Kitamura,et al. Genomic structure and chromosomal localization of the human hepatocyte growth factor activator inhibitor type 1 and 2 genes. , 2000, European journal of biochemistry.
[28] K. Miyazawa,et al. Mouse hepatocyte growth factor activator gene: its expression not only in the liver but also in the gastrointestinal tract. , 2000, Biochimica et biophysica acta.
[29] D. Stolz,et al. Cross-talk between Epidermal Growth Factor Receptor and c-Met Signal Pathways in Transformed Cells* , 2000, The Journal of Biological Chemistry.
[30] G. Merlino,et al. Disassociation of Met-Mediated Biological Responses In Vivo: the Natural Hepatocyte Growth Factor/Scatter Factor Splice Variant NK2 Antagonizes Growth but Facilitates Metastasis , 2000, Molecular and Cellular Biology.
[31] K. Nabeshima,et al. Conserved expression of hepatocyte growth factor activator inhibitor type-2/placental bikunin in human colorectal carcinomas. , 2000, Cancer letters.
[32] S. Mitsui,et al. Hair cycle-dependent expression of hepatocyte growth factor (HGF) activator, other proteinases, and proteinase inhibitors correlates with the expression of HGF in rat hair follicles. , 1999, The journal of investigative dermatology. Symposium proceedings.
[33] K. Matsumoto,et al. Multiple sites of proteolytic cleavage to release soluble forms of hepatocyte growth factor activator inhibitor type 1 from a transmembrane form. , 1999, Journal of biochemistry.
[34] C. Craik,et al. Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[35] H. Dietz,et al. Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression. , 1999, Journal of the National Cancer Institute.
[36] M. Seiki,et al. Regulation of matrix metalloproteinase‐2 (MMP‐2) by hepatocyte growth factor/scatter factor (HGF/SF) in human glioma cells: HGF/SF enhances MMP‐2 expression and activation accompanying up‐regulation of membrane type‐1 MMP , 1999, International journal of cancer.
[37] M. Johnson,et al. Molecular Cloning of cDNA for Matriptase, a Matrix-degrading Serine Protease with Trypsin-like Activity* , 1999, The Journal of Biological Chemistry.
[38] M. Johnson,et al. Purification and Characterization of a Complex Containing Matriptase and a Kunitz-type Serine Protease Inhibitor from Human Milk* , 1999, The Journal of Biological Chemistry.
[39] K. Nabeshima,et al. Distribution of Hepatocyte Growth Factor Activator Inhibitor Type 1 (HAI-1) in Human Tissues: Cellular Surface Localization of HAI-1 in Simple Columnar Epithelium and Its Modulated Expression in Injured and Regenerative Tissues , 1999, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[40] N. Kitamura,et al. Hepatocyte growth factor activator inhibitor type 2 lacking the first Kunitz-type serine proteinase inhibitor domain is a predominant product in mouse but not in human. , 1999, Biochemical and biophysical research communications.
[41] M. Omata,et al. Hepatocyte growth factor activator: a possible regulator of morphogenesis during fetal development of the rat gastrointestinal tract. , 1998, Biochemical and biophysical research communications.
[42] N. Shimizu,et al. Structural organization and chromosomal localization of the human hepatocyte growth factor activator gene--phylogenetic and functional relationship with blood coagulation factor XII, urokinase, and tissue-type plasminogen activator. , 1998, European journal of biochemistry.
[43] N. Kitamura,et al. Functional characterization of Kunitz domains in hepatocyte growth factor activator inhibitor type 2 , 1998, FEBS letters.
[44] H. Kataoka,et al. Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells. , 1998, Biochemical and biophysical research communications.
[45] Y. Itoyama,et al. Inductions of hepatocyte growth factor and its activator in rat brain with permanent middle cerebral artery occlusion , 1998, Brain Research.
[46] K. Nabeshima,et al. Evaluation of hepatocyte growth factor activator inhibitor expression in normal and malignant colonic mucosa. , 1998, Cancer letters.
[47] G. Merlino,et al. NK1, a Natural Splice Variant of Hepatocyte Growth Factor/Scatter Factor, Is a Partial Agonist In Vivo , 1998, Molecular and Cellular Biology.
[48] H. Friess,et al. Cloning of a new Kunitz-type protease inhibitor with a putative transmembrane domain overexpressed in pancreatic cancer. , 1998, Biochimica et biophysica acta.
[49] K. Matsumoto,et al. Purification and Cloning of Hepatocyte Growth Factor Activator Inhibitor Type 2, a Kunitz-type Serine Protease Inhibitor* , 1997, The Journal of Biological Chemistry.
[50] T Nakamura,et al. Hepatocyte growth factor (HGF) as a tissue organizer for organogenesis and regeneration. , 1997, Biochemical and biophysical research communications.
[51] K. Nabeshima,et al. Analysis of tissue factor and tissue factor pathway inhibitor expression in human colorectal carcinoma cell lines and metastatic sublines to the liver , 1997, International journal of cancer.
[52] J. Greve,et al. Identification and Cloning of Human Placental Bikunin, a Novel Serine Protease Inhibitor Containing Two Kunitz Domains* , 1997, The Journal of Biological Chemistry.
[53] S. Roczniak,et al. Characterization of Placental Bikunin, a Novel Human Serine Protease Inhibitor* , 1997, The Journal of Biological Chemistry.
[54] S. Scherer,et al. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas , 1997, Nature Genetics.
[55] K. Miyazawa,et al. Hepatocyte Growth Factor Activator Inhibitor, a Novel Kunitz-type Serine Protease Inhibitor* , 1997, The Journal of Biological Chemistry.
[56] L. Jin,et al. Scatter factor stimulates tumor growth and tumor angiogenesis in human breast cancers in the mammary fat pads of nude mice. , 1997, Laboratory investigation; a journal of technical methods and pathology.
[57] K. Miyazawa,et al. Induction of hepatocyte growth factor activator messenger RNA in the liver following tissue injury and acute inflammation , 1997, Hepatology.
[58] P. Comoglio,et al. Overexpression and activation of hepatocyte growth factor/scatter factor in human non-small-cell lung carcinomas. , 1996, British Journal of Cancer.
[59] D. Stolz,et al. Presence of urokinase in serum-free primary rat hepatocyte cultures and its role in activating hepatocyte growth factor. , 1996, Cancer research.
[60] K. Matsumoto,et al. Emerging multipotent aspects of hepatocyte growth factor. , 1996, Journal of biochemistry.
[61] G. V. Vande Woude,et al. Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network , 1996, Molecular and cellular biology.
[62] K. Miyazawa,et al. Activation of Hepatocyte Growth Factor in the Injured Tissues Is Mediated by Hepatocyte Growth Factor Activator (*) , 1996, The Journal of Biological Chemistry.
[63] N. Rahimi,et al. Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinoma. , 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[64] H. Tsubouchi,et al. Concomitant expression of hepatocyte growth factor (HGF), HGF activator and c‐met genes in human glioma cells in vitro , 1995, FEBS letters.
[65] Carmen Birchmeier,et al. Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud , 1995, Nature.
[66] G. Michalopoulos,et al. The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis , 1995, The Journal of cell biology.
[67] T. Nakamura,et al. Hepatocyte growth factor is the most potent endogenous stimulant of rabbit gastric epithelial cell proliferation and migration in primary culture. , 1995, The Journal of clinical investigation.
[68] K. Miyazawa,et al. Hepatocyte growth factor remains as an inactive single chain after partial hepatectomy or unilateral nephrectomy , 1995, FEBS letters.
[69] K. Miyazawa,et al. Activation of hepatocyte growth factor by two homologous proteases, blood-coagulation factor XIIa and hepatocyte growth factor activator. , 1995, European journal of biochemistry.
[70] Tetsuo Noda,et al. Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor , 1995, Nature.
[71] M. Sharpe,et al. Scatter factor/hepatocyte growth factor is essential for liver development , 1995, Nature.
[72] P. Lollini,et al. The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit. , 1995, Oncogene.
[73] A. Bardelli,et al. Biological Activation of pro-HGF (Hepatocyte Growth Factor) by Urokinase Is Controlled by a Stoichiometric Reaction (*) , 1995, The Journal of Biological Chemistry.
[74] G. V. Vande Woude,et al. Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[75] T. Nakamura,et al. Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity. , 1994, Oncogene.
[76] K. Miyazawa,et al. Proteolytic activation of hepatocyte growth factor in response to tissue injury. , 1994, The Journal of biological chemistry.
[77] K. Miyazawa,et al. Activation of the zymogen of hepatocyte growth factor activator by thrombin. , 1993, The Journal of biological chemistry.
[78] G. Michalopoulos,et al. Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA. , 1993, The American journal of pathology.
[79] K. Miyazawa,et al. Molecular cloning and sequence analysis of the cDNA for a human serine protease reponsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII. , 1993, The Journal of biological chemistry.
[80] T. Nakamura,et al. Proteolytic activation of a single-chain precursor of hepatocyte growth factor by extracellular serine-protease. , 1992, Biochemical and biophysical research communications.
[81] W. Birchmeier,et al. Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. , 1992, The EMBO journal.
[82] J. Rubin,et al. Processing of hepatocyte growth factor to the heterodimeric form is required for biological activity , 1992, FEBS letters.
[83] K. Miyazawa,et al. Activation of hepatocyte growth factor by proteolytic conversion of a single chain form to a heterodimer. , 1992, The Journal of biological chemistry.
[84] A. Bardelli,et al. Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. , 1991, The EMBO journal.
[85] W. Birchmeier,et al. Evidence for the identity of human scatter factor and human hepatocyte growth factor. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[86] S. Hirono,et al. Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. , 1988, The Journal of clinical investigation.
[87] Toshikazu Nakamura,et al. Purification and subunit structure of hepatocyte growth factor from rat platelets , 1987, FEBS letters.
[88] Michael Stoker,et al. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility , 1987, Nature.
[89] H. Dvorak. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. , 1986, The New England journal of medicine.
[90] J. Kondo,et al. A novel protease obtained from FBS-containing culture supernatant, that processes single chain form hepatocyte growth factor to two chain form in serum-free culture , 2006, Cytotechnology.
[91] T. Taher,et al. Cross-talk between CD44 and c-Met in B cells. , 1999, Current topics in microbiology and immunology.
[92] Y. Matsushima,et al. Production and activation of hepatocyte growth factor during the healing of rat gastric ulcers. , 1997, Digestion.