Ensemble Activity and Behavior—What's the Code?

The brain represents information in a distributed code, carried by action potentials in ensembles of neurons. Ensemble activity can now be monitored by multielectrode arrays in behaving animals. Deadwyler and Hampson describe recent results that illustrate how the brain may code behavior in ensembles of neurons.

[1]  M. Nicolelis,et al.  Induction of immediate spatiotemporal changes in thalamic networks by peripheral block of ascending cutaneous information , 1993, Nature.

[2]  D. Gardner The neurobiology of neural networks , 1993 .

[3]  Geoffrey E. Hinton,et al.  Parallel Models of Associative Memory , 1989 .

[4]  F. Frankel,et al.  Biological Sciences: Role of ATP in DNA Replication , 1973, Nature.

[5]  T. Teyler,et al.  Long-term potentiation. , 1987, Annual review of neuroscience.

[6]  W. Schultz,et al.  Responses of monkey dopamine neurons to reward and conditioned stimuli during successive steps of learning a delayed response task , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[7]  Michael J. Daly,et al.  Resistance to Radiation , 1995, Science.

[8]  B L McNaughton,et al.  Dynamics of the hippocampal ensemble code for space. , 1993, Science.

[9]  H Eichenbaum,et al.  The organization of spatial coding in the hippocampus: a study of neural ensemble activity , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[10]  J. J. Hopfield,et al.  Pattern recognition computation using action potential timing for stimulus representation , 1995, Nature.

[11]  J J Hopfield,et al.  Rapid local synchronization of action potentials: toward computation with coupled integrate-and-fire neurons. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[12]  M. Nicolelis,et al.  Spatiotemporal structure of somatosensory responses of many-neuron ensembles in the rat ventral posterior medial nucleus of the thalamus , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[13]  E T Rolls,et al.  Computational constraints suggest the need for two distinct input systems to the hippocampal CA3 network , 1992, Hippocampus.

[14]  E. Capaldi,et al.  The organization of behavior. , 1992, Journal of applied behavior analysis.

[15]  M. Arbib,et al.  Grasping objects: the cortical mechanisms of visuomotor transformation , 1995, Trends in Neurosciences.

[16]  C. Gross,et al.  Neural ensemble coding in inferior temporal cortex. , 1994, Journal of neurophysiology.

[17]  Richard Durbin,et al.  The computing neuron , 1989 .

[18]  J. T. Massey,et al.  Mental rotation of the neuronal population vector. , 1989, Science.

[19]  L. Nadel,et al.  The Hippocampus as a Cognitive Map , 1978 .

[20]  G Stürzenhofecker The spirit of the gift. , 1993, Science.

[21]  J E Lisman,et al.  Storage of 7 +/- 2 short-term memories in oscillatory subcycles , 1995, Science.

[22]  R. Muller,et al.  On the directional firing properties of hippocampal place cells , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[23]  Terrence J. Sejnowski,et al.  The Computational Brain , 1996, Artif. Intell..

[24]  J. Stevens,et al.  Applied Multivariate Statistics for the Social Sciences , 1993 .