A gerophysiology perspective on healthy ageing

[1]  E. Pearce,et al.  Metabolic orchestration of the wound healing response. , 2021, Cell metabolism.

[2]  G. Mithieux,et al.  Driving regeneration, instead of healing, in adult mammals: the decisive role of resident macrophages through efferocytosis , 2021, npj Regenerative Medicine.

[3]  J. Beard,et al.  Intrinsic Capacity: Validation of a New WHO Concept for Healthy Ageing in a Longitudinal Chinese Study. , 2021, The journals of gerontology. Series A, Biological sciences and medical sciences.

[4]  C. Franceschi.  Aging, Inflammaging and Adaptation: Comment on "Dynamic and thermodynamic models of adaptation" by A.N. Gorban et al. , 2021, Physics of Life Reviews.

[5]  Liu Cao,et al.  Adipose‐derived stem cells regulate metabolic homeostasis and delay aging by promoting mitophagy , 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[6]  S. Diao,et al.  The role and mechanism of mitochondrial functions and energy metabolism in the function regulation of the mesenchymal stem cells , 2021, Stem cell research & therapy.

[7]  I. Weissman,et al.  Restoring metabolism of myeloid cells reverses cognitive decline in ageing , 2021, Nature.

[8]  L. Casteilla,et al.  Endogenous Mobilization of Mesenchymal Stromal Cells: A Pathway for Interorgan Communication? , 2021, Frontiers in Cell and Developmental Biology.

[9]  Sébastien J. Thuault.  Reflections on aging research from within the National Institute on Aging , 2021, Nature Aging.

[10]  J. Neuzil,et al.  Platelets Facilitate the Wound-Healing Capability of Mesenchymal Stem Cells by Mitochondrial Transfer and Metabolic Reprogramming. , 2020, Cell metabolism.

[11]  Sandeep P. Dumbali,et al.  Mitochondrial Transfer and Regulators of Mesenchymal Stromal Cell Function and Therapeutic Efficacy , 2020, Frontiers in Cell and Developmental Biology.

[12]  Wei-Qiang Tan,et al.  The Roles of Inflammation in Keloid and Hypertrophic Scars , 2020, Frontiers in Immunology.

[13]  K. Scharffetter-Kochanek,et al.  Mesenchymal Stem Cells Adaptively Respond to Environmental Cues Thereby Improving Granulation Tissue Formation and Wound Healing , 2020, Frontiers in Cell and Developmental Biology.

[14]  Christoph Bock,et al.  Structural cells are key regulators of organ-specific immune response , 2020, Nature.

[15]  James T. Webber,et al.  Aging hallmarks exhibit organ-specific temporal signatures , 2020, Nature.

[16]  R. Smolarczyk,et al.  The World Health Organization (WHO) approach to healthy ageing , 2020, Maturitas.

[17]  M. Desco,et al.  T cells with dysfunctional mitochondria induce multimorbidity and premature senescence , 2020, Science.

[18]  P. Robson,et al.  Transplanting cells from old but not young donors causes physical dysfunction in older recipients , 2020, Aging cell.

[19]  M. Jackson.  Mechanistic models to guide redox investigations and interventions in musculoskeletal ageing. , 2020, Free radical biology & medicine.

[20]  T. Kirkwood,et al.  Age-related macular degeneration: A two-level model hypothesis , 2019, Progress in Retinal and Eye Research.

[21]  P. Muñoz-Cánoves,et al.  Understanding muscle regenerative decline with aging: new approaches to bring back youthfulness to aged stem cells , 2019, The FEBS journal.

[22]  M. Pittenger,et al.  Mesenchymal stem cell perspective: cell biology to clinical progress , 2019, npj Regenerative Medicine.

[23]  M. Cesari,et al.  The structure and predictive value of intrinsic capacity in a longitudinal study of ageing , 2019, BMJ Open.

[24]  L. Fried,et al.  Frailty: implications for clinical practice and public health , 2019, The Lancet.

[25]  P. Kapahi,et al.  From discoveries in ageing research to therapeutics for healthy ageing , 2019, Nature.

[26]  Martin Feelisch,et al.  The Redox architecture of physiological function , 2019, Current opinion in physiology.

[27]  R. Naviaux.  Metabolic features and regulation of the healing cycle-A new model for chronic disease pathogenesis and treatment. , 2019, Mitochondrion.

[28]  J. Cooke.  Inflammation and Its Role in Regeneration and Repair. , 2019, Circulation research.

[29]  R. Medzhitov,et al.  Counting Calories: The Cost of Inflammation , 2019, Cell.

[30]  K. Charlot,et al.  Physiology of energy homeostasis: Models, actors, challenges and the glucoadipostatic loop. , 2019, Metabolism: clinical and experimental.

[31]  Eric J Topol,et al.  High-performance medicine: the convergence of human and artificial intelligence , 2019, Nature Medicine.

[32]  C. Franceschi,et al.  Inflammaging: a new immune–metabolic viewpoint for age-related diseases , 2018, Nature Reviews Endocrinology.

[33]  Corby K. Martin,et al.  Metabolic Slowing and Reduced Oxidative Damage with Sustained Caloric Restriction Support the Rate of Living and Oxidative Damage Theories of Aging. , 2018, Cell metabolism.

[34]  Neil D. Theise,et al.  Structure and Distribution of an Unrecognized Interstitium in Human Tissues , 2018, Scientific Reports.

[35]  H. Fuchs,et al.  Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice , 2018, Proceedings of the National Academy of Sciences.

[36]  T. Wynn,et al.  Type 2 immunity in tissue repair and fibrosis , 2017, Nature Reviews Immunology.

[37]  Paul Martin,et al.  Inflammation and metabolism in tissue repair and regeneration , 2017, Science.

[38]  C. Cooper,et al.  Epidemiology of sarcopenia and insight into possible therapeutic targets , 2017, Nature Reviews Rheumatology.

[39]  Douglas E. Vaughan,et al.  Molecular and physiological manifestations and measurement of aging in humans , 2017, Aging cell.

[40]  B. Goodpaster,et al.  Metabolic Flexibility in Health and Disease. , 2017, Cell metabolism.

[41]  G. Hotamışlıgil.  Inflammation, metaflammation and immunometabolic disorders , 2017, Nature.

[42]  R. Kohanski,et al.  Geroscience and the trans-NIH Geroscience Interest Group, GSIG , 2017, GeroScience.

[43]  H. Cohen,et al.  Disease drivers of aging , 2016, Annals of the New York Academy of Sciences.

[44]  F. Sierra,et al.  Resilience in Aging Mice. , 2016, The journals of gerontology. Series A, Biological sciences and medical sciences.

[45]  B. Hinz.  The role of myofibroblasts in wound healing. , 2016, Current research in translational medicine.

[46]  D. Ramsay,et al.  Physiological Regulation: How It Really Works. , 2016, Cell metabolism.

[47]  R. Kalluri.  The biology and function of fibroblasts in cancer , 2016, Nature Reviews Cancer.

[48]  Ritu Sadana,et al.  The World report on ageing and health: a policy framework for healthy ageing , 2016, The Lancet.

[49]  D. Seals,et al.  Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity , 2016, The Journal of physiology.

[50]  J. V. van Beek,et al.  Understanding the physiology of the ageing individual: computational modelling of changes in metabolism and endurance , 2016, Interface Focus.

[51]  L. Ferrucci,et al.  Homeostatic dysregulation proceeds in parallel in multiple physiological systems , 2015, Aging cell.

[52]  Dean P. Jones,et al.  The Redox Code , 2015, Antioxidants & redox signaling.

[53]  Alan Trounson,et al.  Stem Cell Therapies in Clinical Trials: Progress and Challenges. , 2015, Cell stem cell.

[54]  B. Vogelstein,et al.  Cancer risk: Role of environment—Response , 2015, Science.

[55]  B. Vogelstein,et al.  Variation in cancer risk among tissues can be explained by the number of stem cell divisions , 2015, Science.

[56]  E. Schadt,et al.  Geroscience: Linking Aging to Chronic Disease , 2014, Cell.

[57]  Wei Cao,et al.  Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications , 2014, Nature Immunology.

[58]  N. Rosenthal,et al.  Preparing the ground for tissue regeneration: from mechanism to therapy , 2014, Nature Medicine.

[59]  E. Olson,et al.  Immune modulation of stem cells and regeneration. , 2014, Cell stem cell.

[60]  R. Weindruch,et al.  Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys , 2014, Nature Communications.

[61]  D. Ramsay,et al.  Clarifying the roles of homeostasis and allostasis in physiological regulation. , 2014, Psychological review.

[62]  Manuel Serrano,et al.  The Hallmarks of Aging , 2013, Cell.

[63]  S. Iliffe,et al.  Frailty in elderly people , 2013, The Lancet.

[64]  L. Fratiglioni,et al.  Aging with multimorbidity: A systematic review of the literature , 2011, Ageing Research Reviews.

[65]  David M. Gardiner,et al.  The Axolotl Model for Regeneration and Aging Research: A Mini-Review , 2011, Gerontology.

[66]  M. Jensen,et al.  Fat tissue, aging, and cellular senescence , 2010, Aging cell.

[67]  Hiroyuki Miyoshi,et al.  The Role of Stromal Stem Cells in Tissue Regeneration and Wound Repair , 2009, Science.

[68]  A. Uccelli,et al.  Mesenchymal stem cells in health and disease , 2008, Nature Reviews Immunology.

[69]  A. Mitnitski,et al.  Frailty in relation to the accumulation of deficits. , 2007, The journals of gerontology. Series A, Biological sciences and medical sciences.

[70]  G. Hotamisligil,et al.  Inflammation and metabolic disorders , 2006, Nature.

[71]  A. Carrière,et al.  Adipose Tissue Proadipogenic Redox Changes in Obesity* , 2006, Journal of Biological Chemistry.

[72]  T. Kirkwood,et al.  Understanding the Odd Science of Aging , 2005, Cell.

[73]  T. Seeman,et al.  Protective and Damaging Effects of Mediators of Stress: Elaborating and Testing the Concepts of Allostasis and Allostatic Load , 1999, Annals of the New York Academy of Sciences.

[74]  Bruce Mcewen,et al.  Stress, Adaptation, and Disease: Allostasis and Allostatic Load , 1998, Annals of the New York Academy of Sciences.

[75]  R. Weindruch,et al.  Caloric Intake and Aging , 1997 .

[76]  H. Dvorak.  Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. , 1986, The New England journal of medicine.

[77]  P. Kerndt,et al.  Fasting: the history, pathophysiology and complications. , 1982, The Western journal of medicine.

[78]  J. Nikolich-Žugich.  The twilight of immunity: emerging concepts in aging of the immune system , 2017, Nature Immunology.

[79]  A. Galinier,et al.  Aging-related decrease of human ASC angiogenic potential is reversed by hypoxia preconditioning through ROS production. , 2013, Molecular Therapy.