Factors influencing pediatric transfusion: A complex decision impacting quality of care

The risks of red blood cell transfusion may outweigh the benefits for many patients in pediatric intensive care units (PICUs), but guidelines from the Transfusion and Anemia eXpertise Initiative (TAXI) have not been consistently adopted. We sought to identify factors that influenced transfusion decision‐making in PICUs to explore potential barriers and facilitators to implementing the guidelines.

[1]  Laura M. Holdsworth,et al.  Factors Influencing Implementation of Blood Transfusion Recommendations in Pediatric Critical Care Units , 2021, Frontiers in Pediatrics.

[2]  J. Vincent,et al.  Transfusion in the mechanically ventilated patient , 2020, Intensive Care Medicine.

[3]  Laura M. Holdsworth,et al.  Implementation of clinical practice changes in the PICU: a qualitative study using and refining the iPARIHS framework , 2020, Implementation Science.

[4]  Wei Zhang,et al.  Liberal Transfusion versus Restrictive Transfusion and Outcomes in Critically Ill Adults: A Meta-Analysis , 2020, Transfusion Medicine and Hemotherapy.

[5]  C. Traube,et al.  Association Between Transfusion of RBCs and Subsequent Development of Delirium in Critically Ill Children* , 2018, Pediatric Critical Care Medicine.

[6]  J. Fortenberry,et al.  Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative , 2018, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[7]  M. Dahmer,et al.  Mechanisms of red blood cell transfusion‐related immunomodulation , 2018, Transfusion.

[8]  C. Weiss.  Why do we fail to deliver evidence-based practice in critical care medicine? , 2017, Current opinion in critical care.

[9]  David A Chambers,et al.  Leveraging Implementation Science to Improve Cancer Care Delivery and Patient Outcomes. , 2017, Journal of oncology practice.

[10]  J. Acker,et al.  Transfusion‐related immunomodulation: review of the literature and implications for pediatric critical illness , 2017, Transfusion.

[11]  Sanjay R. Patel,et al.  An Official American Thoracic Society Research Statement: Implementation Science in Pulmonary, Critical Care, and Sleep Medicine. , 2016, American journal of respiratory and critical care medicine.

[12]  S. Fortin,et al.  Blood transfusion in acute and chronic pediatric settings: beliefs and practices , 2016, Transfusion.

[13]  R. Habib,et al.  Role of blood transfusion product type and amount in deep vein thrombosis after cardiac surgery. , 2015, Thrombosis research.

[14]  Naihua Duan,et al.  Purposeful Sampling for Qualitative Data Collection and Analysis in Mixed Method Implementation Research , 2015, Administration and Policy in Mental Health and Mental Health Services Research.

[15]  J. Lacroix,et al.  Survey on Stated Transfusion Practices in PICUs* , 2014, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[16]  P. Spinella,et al.  Role of Transfused Red Blood Cells for Shock and Coagulopathy Within Remote Damage Control Resuscitation , 2014, Shock.

[17]  S. Salpeter,et al.  Impact of more restrictive blood transfusion strategies on clinical outcomes: a meta-analysis and systematic review. , 2014, The American journal of medicine.

[18]  J. Ritchie,et al.  Qualitative Research Practice: A Guide for Social Science Students and Researchers , 2013 .

[19]  David J Murphy,et al.  Changes in Transfusion Practice Over Time in the PICU* , 2013, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[20]  H. Trottier,et al.  Red blood cell transfusion in critically ill children (CME) , 2013, Transfusion.

[21]  J. Wetterslev,et al.  Association of blood transfusion with increased mortality in myocardial infarction: a meta-analysis and diversity-adjusted study sequential analysis. , 2013, JAMA internal medicine.

[22]  M. Poca,et al.  Transfusion strategies for acute upper gastrointestinal bleeding. , 2013, The New England journal of medicine.

[23]  J. Grimshaw,et al.  A cross-country comparison of intensive care physicians’ beliefs about their transfusion behaviour: A qualitative study using the theoretical domains framework , 2012, Implementation Science.

[24]  P. Spinella,et al.  Effect of processing and storage on red blood cell function in vivo. , 2012, Seminars in perinatology.

[25]  B. Chaitman,et al.  Liberal or restrictive transfusion in high-risk patients after hip surgery. , 2011, The New England journal of medicine.

[26]  N. B. Lerner,et al.  Children with single-ventricle physiology do not benefit from higher hemoglobin levels post cavopulmonary connection: Results of a prospective, randomized, controlled trial of a restrictive versus liberal red-cell transfusion strategy* , 2011, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[27]  J. Vincent,et al.  Transfusion requirements after cardiac surgery: the TRACS randomized controlled trial. , 2010, JAMA.

[28]  C. Silliman,et al.  Transfusion‐related acute lung injury (TRALI): a clinical review with emphasis on the critically ill , 2009, British journal of haematology.

[29]  Marie Johnston,et al.  Evidence-based selection of theories for designing behaviour change interventions: using methods based on theoretical construct domains to understand clinicians' blood transfusion behaviour. , 2009, British journal of health psychology.

[30]  P. Marik,et al.  Efficacy of red blood cell transfusion in the critically ill: A systematic review of the literature* , 2008, Critical care medicine.

[31]  J. Twisk,et al.  Red blood cell transfusion in critically ill children is independently associated with increased mortality , 2007, Intensive Care Medicine.

[32]  J. Collet,et al.  Transfusion strategies for patients in pediatric intensive care units. , 2007, The New England journal of medicine.

[33]  C. Abraham,et al.  Making psychological theory useful for implementing evidence based practice: a consensus approach , 2005, Quality and Safety in Health Care.

[34]  C. Infante-Rivard,et al.  Survey on transfusion practices of pediatric intensivists* , 2002, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[35]  L. Spencer,et al.  Qualitative data analysis for applied policy research , 2002 .

[36]  G. Wells,et al.  A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. , 1999, The New England journal of medicine.

[37]  R. Steketee,et al.  Longitudinal evaluation of severely anemic children in Kenya: the effect of transfusion on mortality and hematologic recovery , 1997, AIDS.

[38]  A. Huberman,et al.  Qualitative Data Analysis: A Methods Sourcebook , 1994 .

[39]  R. Steketee,et al.  Effect of blood transfusion on survival among children in a Kenyan hospital , 1992, The Lancet.

[40]  J. Avorn,et al.  Influence of clinical knowledge, organizational context, and practice style on transfusion decision making. Implications for practice change strategies. , 1990, JAMA.

[41]  P. Sperryn,et al.  Blood. , 1989, British journal of sports medicine.

[42]  A. D’Alessandro,et al.  Red blood cell storage lesion: causes and potential clinical consequences. , 2019, Blood transfusion = Trasfusione del sangue.

[43]  Michael F Swartz,et al.  Outcomes Using a Conservative Versus Liberal Red Blood Cell Transfusion Strategy in Infants Requiring Cardiac Operation. , 2017, The Annals of thoracic surgery.