Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility.
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E. Hu | R. Kunz | N. Chen | S. Chmait | J. Treanor | H. Monenschein | R. Rzasa | Amy C Porter | Xiaoning Zhao | Jennifer R. Allen | Silke Miller | C. Davis | Daniel B Horne | A. Reichelt | Heather Eastwood | Matthew R. Kaller | M. Frohn | Alexander J. Pickrell | Jeff Clarine | Thomas T. Nguyen | Adrie D Jones | K. Andrews | Holger Monenschein