Health impact of nanotechnologies in food production

This report gives an overview and an advice for priority of scientific issues that need to be addressed in order to improve the process of risk assessment for nanoparticles in food and in order to gain insight in dossier requirements for nanoparticles in food.

[1]  T. Xia,et al.  Toxic Potential of Materials at the Nanolevel , 2006, Science.

[2]  Mihail C. Roco,et al.  Nanoscale Science and Engineering: Unifying and Transforming Tools , 2004 .

[3]  Karluss Thomas,et al.  Research strategies for safety evaluation of nanomaterials, Part I: evaluating the human health implications of exposure to nanoscale materials. , 2005, Toxicological sciences : an official journal of the Society of Toxicology.

[4]  Andrew D. Maynard,et al.  Nanotechnology: assessing the risks , 2006 .

[5]  J. Weiss,et al.  Liposomal Nanocapsules in Food Science and Agriculture , 2005, Critical reviews in food science and nutrition.

[6]  Gabriel A Silva,et al.  Nanotechnology approaches for drug and small molecule delivery across the blood brain barrier. , 2007, Surgical neurology.

[7]  Lide Zhang,et al.  Comparison of short-term toxicity between Nano-Se and selenite in mice. , 2005, Life sciences.

[8]  Nazila Salamat-Miller,et al.  Current strategies used to enhance the paracellular transport of therapeutic polypeptides across the intestinal epithelium. , 2005, International journal of pharmaceutics.

[9]  R. Duncan,et al.  Dendrimer biocompatibility and toxicity. , 2005, Advanced drug delivery reviews.

[10]  F. Shahidi,et al.  Nanotechnology in nutraceuticals and functional foods , 2006 .

[11]  Jayanth Panyam,et al.  Biodegradable nanoparticles for drug and gene delivery to cells and tissue. , 2003, Advanced drug delivery reviews.

[12]  G. Russell-Jones,et al.  Lectin-mediated transport of nanoparticles across Caco-2 and OK cells. , 1999, International journal of pharmaceutics.

[13]  A. Ulrich.  Biophysical Aspects of Using Liposomes as Delivery Vehicles , 2002, Bioscience reports.

[14]  R. Müller,et al.  Nanosuspensions as particulate drug formulations in therapy. Rationale for development and what we can expect for the future. , 2001, Advanced drug delivery reviews.

[15]  M. Prato,et al.  Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[16]  M. Hashida,et al.  Uptake by hepatocytes and biliary excretion of intravenously administered polystyrene microspheres in rats. , 1999, Journal of drug targeting.

[17]  T. Tsuchiya,et al.  Novel harmful effects of [60]fullerene on mouse embryos in vitro and in vivo , 1996, FEBS letters.

[18]  O. Preining.  The physical nature of very, very small particles and its impact on their behaviour , 1998 .

[19]  Y. Bao,et al.  Biological effects of a nano red elemental selenium , 2001, BioFactors.

[20]  Stephen M. Roberts,et al.  Characterization of the size, shape, and state of dispersion of nanoparticles for toxicological studies , 2007 .

[21]  G. Oberdörster,et al.  Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles , 2005, Environmental health perspectives.

[22]  S. Schürch,et al.  Interaction of fine particles and nanoparticles with red blood cells visualized with advanced microscopic techniques. , 2006, Environmental science & technology.

[23]  P. Méléard,et al.  Physical and chemical stability of marine lipid-based liposomes under acid conditions. , 2001, Colloids and surfaces. B, Biointerfaces.

[24]  Krishnendu Roy,et al.  Oral gene delivery with chitosan–DNA nanoparticles generates immunologic protection in a murine model of peanut allergy , 1999, Nature Medicine.

[25]  M. Cansell,et al.  Marine lipid-based liposomes increase in vivo FA bioavailability , 2003, Lipids.

[26]  Z. Chai,et al.  Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. , 2007, Toxicology letters.

[27]  C. Divya,et al.  Nanoscience and Nanotechnology , 2007 .

[28]  F. Wudl,et al.  Pharmacokinetics of a water-soluble fullerene in rats , 1996, Antimicrobial agents and chemotherapy.

[29]  J Kleiner,et al.  Assessment of intake from the diet. , 2002, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[30]  Julie W. Fitzpatrick,et al.  Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy , 2005, Particle and Fibre Toxicology.

[31]  Wang Guobin,et al.  Preparation and acute toxicology of nano-magnetic ferrofluid , 2008, Journal of Huazhong University of Science and Technology [Medical Sciences].

[32]  J. Kraehenbuhl,et al.  Epithelial M cells: differentiation and function. , 2000, Annual review of cell and developmental biology.

[33]  S. Pratsinis,et al.  Synthesis, characterization, and bioavailability in rats of ferric phosphate nanoparticles. , 2007, The Journal of nutrition.

[34]  Geertsma Re,et al.  Nanotechnology in medical applications:state-of-the-art in materials and devices , 2005 .

[35]  L. Mortelmans,et al.  Passage of Inhaled Particles Into the Blood Circulation in Humans , 2002, Circulation.

[36]  Jochen Weiss,et al.  Functional Materials in Food Nanotechnology , 2006 .

[37]  J. West,et al.  The Differential Cytotoxicity of Water-Soluble Fullerenes , 2004 .

[38]  Feng Zhao,et al.  Acute toxicological effects of copper nanoparticles in vivo. , 2006, Toxicology letters.

[39]  M. Hashida,et al.  Hepatic uptake of polystyrene microspheres in rats: effect of particle size on intrahepatic distribution. , 1999, Journal of controlled release : official journal of the Controlled Release Society.

[40]  Meng Wang,et al.  Acute toxicity of nano- and micro-scale zinc powder in healthy adult mice. , 2006, Toxicology letters.