Diagnostic Ultrasound Impulses Improve Microvascular Flow in Patients With STEMI Receiving Intravenous Microbubbles.

We read with interest the paper by Mathias et al. [(1)][1], testing the hypothesis that the transthoracic high mechanical index impulses from ultrasound, used as a diagnostic tool to detect microvascular obstruction, may be used to improve the epicardial and microvascular flow in patients with

[1]  A. M. Leone,et al.  The combined effect of subcutaneous granulocyte- colony stimulating factor and myocardial contrast echocardiography with intravenous infusion of sulfur hexafluoride on post-infarction left ventricular function, the RIGENERA 2.0 trial: study protocol for a randomized controlled trial , 2016, Trials.

[2]  R. Correa-Araujo,et al.  Cardiac levels of norepinephrine, dopamine, serotonin and histamine in Chagas' disease. , 1991, International journal of cardiology.

[3]  Pedro A. Lemos,et al.  Diagnostic Ultrasound Impulses Improve Microvascular Flow in Patients With STEMI Receiving Intravenous Microbubbles. , 2016, Journal of the American College of Cardiology.

[4]  A. M. Leone,et al.  From bone marrow to the arterial wall: the ongoing tale of endothelial progenitor cells. , 2008, European heart journal.

[5]  K. Adams,et al.  Selective versus nonselective beta-blockade for heart failure therapy: are there lessons to be learned from the COMET trial? , 2003, Journal of cardiac failure.

[6]  M. Bristow,et al.  Anthracycline-associated cardiac and renal damage in rabbits. Evidence for mediation by vasoactive substances. , 1981, Laboratory investigation; a journal of technical methods and pathology.

[7]  Yunhua Gao,et al.  Myocardium-targeted transplantation of mesenchymal stem cells by diagnostic ultrasound-mediated microbubble destruction improves cardiac function in myocardial infarction of New Zealand rabbits. , 2010, International journal of cardiology.