Adenovirus DNA Polymerase Loses Fidelity on a Stretch of Eleven Homocytidines during Pre-GMP Vaccine Preparation
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T. Hanke | S. Di Marco | S. Colloca | Alison Crook | E. Wee | Z. Hannoun
[1] B. Korber,et al. Effect of epitope variant co-delivery on the depth of CD8 T cell responses induced by HIV-1 conserved mosaic vaccines , 2021, Molecular therapy. Methods & clinical development.
[2] John C W Lim,et al. Measuring Progress of Regulatory Convergence and Cooperation Among Asia–Pacific Economic Cooperation (APEC) Member Economies in the Context of the COVID-19 Pandemic , 2021, Therapeutic Innovation & Regulatory Science.
[3] Wei Zhou,et al. Reshaping cell line development and CMC strategy for fast responses to pandemic outbreak , 2020, Biotechnology progress.
[4] Nguyen H. Tran,et al. Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial , 2020, The Lancet.
[5] A. Franklin,et al. A proposed reverse transcription mechanism for (CAG)n and similar expandable repeats that cause neurological and other diseases , 2020, Heliyon.
[6] B. Korber,et al. T cell-based strategies for HIV-1 vaccines , 2019, Human vaccines & immunotherapeutics.
[7] T. Hanke. Aiming for protective T-cell responses: a focus on the first generation conserved-region HIVconsv vaccines in preventive and therapeutic clinical trials , 2019, Expert review of vaccines.
[8] B. Clotet,et al. Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study) , 2019, EClinicalMedicine.
[9] S. Faust,et al. Heterologous Two-Dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-Lasting Cellular Immunity to Influenza Virus A in Healthy Adults , 2018, EBioMedicine.
[10] W. Jaoko,et al. Broad HIV-1 inhibition in vitro by vaccine-elicited CD8+ T cells in African adults , 2016, Molecular therapy. Methods & clinical development.
[11] A. McMichael,et al. Novel Conserved-region T-cell Mosaic Vaccine With High Global HIV-1 Coverage Is Recognized by Protective Responses in Untreated Infection. , 2016, Molecular therapy : the journal of the American Society of Gene Therapy.
[12] E. Karita,et al. A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of Electroporated HIV DNA with or without Interleukin 12 in Prime-Boost Combinations with an Ad35 HIV Vaccine in Healthy HIV-Seronegative African Adults , 2015, PloS one.
[13] T. Hanke,et al. Safety and Tolerability of Conserved Region Vaccines Vectored by Plasmid DNA, Simian Adenovirus and Modified Vaccinia Virus Ankara Administered to Human Immunodeficiency Virus Type 1-Uninfected Adults in a Randomized, Single-Blind Phase I Trial , 2014, PloS one.
[14] Lucy Dorrell,et al. Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1. , 2014, Molecular therapy : the journal of the American Society of Gene Therapy.
[15] W. Wold,et al. Adenovirus vectors for gene therapy, vaccination and cancer gene therapy. , 2014, Current gene therapy.
[16] A. Hill,et al. Clinical Assessment of a Novel Recombinant Simian Adenovirus ChAdOx1 as a Vectored Vaccine Expressing Conserved Influenza A Antigens , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.
[17] Jennifer A. Johnson,et al. Nonreplicating vectors in HIV vaccines. , 2013, Current opinion in HIV and AIDS.
[18] Taco G. Uil,et al. Adenovirus DNA replication. , 2013, Cold Spring Harbor perspectives in biology.
[19] K. Bojang,et al. A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity , 2012, PloS one.
[20] B. Haynes,et al. Lessons learned from HIV-1 vaccine trials: new priorities and directions , 2012, Nature Immunology.
[21] Ad Davidson,et al. Chromatin structure of adenovirus DNA throughout infection , 2011, Nucleic acids research.
[22] Fernando Castro-Chavez,et al. Most Used Codons per Amino Acid and per Genome in the Code of Man Compared to Other Organisms According to the Rotating Circular Genetic Code. , 2011, NeuroQuantology : an interdisciplinary journal of neuroscience and quantum physics.
[23] C. Turnbough,et al. Regulation of gene expression by reiterative transcription. , 2011, Current opinion in microbiology.
[24] D. Raab,et al. The GeneOptimizer Algorithm: using a sliding window approach to cope with the vast sequence space in multiparameter DNA sequence optimization , 2010, Systems and Synthetic Biology.
[25] D. Barouch. Novel adenovirus vector-based vaccines for HIV-1 , 2010, Current opinion in HIV and AIDS.
[26] S. Plotkin,et al. Vaccines: the Fourth Century , 2009, Clinical and Vaccine Immunology.
[27] Devan V Mehrotra,et al. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial , 2008, The Lancet.
[28] F. He,et al. Relative contributions of codon usage, promoter efficiency and leader sequence to the antigen expression and immunogenicity of HIV-1 Env DNA vaccine. , 2006, Vaccine.
[29] S. Mittal,et al. Development of nonhuman adenoviruses as vaccine vectors , 2005, Vaccine.
[30] D. Webster,et al. Differential Immunogenicity of Various Heterologous Prime-Boost Vaccine Regimens Using DNA and Viral Vectors in Healthy Volunteers1 , 2005, The Journal of Immunology.
[31] M. Ison,et al. Adenovirus , 2016, Microbiology spectrum.
[32] Hildegund C.J. Ertl,et al. Adenoviruses as vaccine vectors , 2004, Molecular Therapy.
[33] A. Moore,et al. Progress in DNA‐based heterologous prime‐boost immunization strategies for malaria , 2004, Immunological reviews.
[34] A. Davison,et al. Genetic content and evolution of adenoviruses. , 2003, The Journal of general virology.
[35] L. M. Albright. Vectors , 2003, Current protocols in molecular biology.
[36] S. Yokoyama,et al. Structure of a T7 RNA polymerase elongation complex at 2.9 Å resolution , 2002, Nature.
[37] A. Hill,et al. Enhanced CD8 T cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes. , 2002, Vaccine.
[38] Takuya Ueda,et al. Cell-free translation reconstituted with purified components , 2001, Nature Biotechnology.
[39] J. Sambrook,et al. Molecular Cloning: A Laboratory Manual , 2001 .
[40] P. Travers,et al. The MHC class I-restricted immune response to HIV-gag in BALB/c mice selects a single epitope that does not have a predictable MHC-binding motif and binds to Kd through interactions between a glutamine at P3 and pocket D. , 1998, Journal of immunology.
[41] J. Haas,et al. Increased Immune Response Elicited by DNA Vaccination with a Synthetic gp120 Sequence with Optimized Codon Usage , 1998, Journal of Virology.
[42] F. Graham,et al. Identification of an immunodominant cytotoxic T-lymphocyte recognition site in glycoprotein B of herpes simplex virus by using recombinant adenovirus vectors and synthetic peptides , 1991, Journal of virology.
[43] S. Zolla-Pazner,et al. Generation of human monoclonal antibodies to human immunodeficiency virus. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[44] P. C. van der Vliet,et al. Temperature-sensitive initiation and elongation of adenovirus DNA replication in vitro with nuclear extracts from H5ts36-, H5ts149-, and H5ts125-infected HeLa cells , 1983, Journal of virology.
[45] F. Graham,et al. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. , 1977, The Journal of general virology.
[46] James Theiler,et al. Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants , 2007, Nature Medicine.
[47] C. Peter,et al. 3 Roles of Transcription Factors in DNA Replication , 1996 .
[48] J. Majors. Translational frameshift suppression in mouse mammary tumor virus and other retroviruses. , 1990, Enzyme.
[49] W. French Anderson,et al. Transcription of single base oligonucleotides by ribonucleic acid- directed deoxyribonucleic acid polymerase , 1976, Nucleic Acids Res..
[50] M. Chamberlin,et al. DEOXYRIBONUCLEIC ACID-DIRECTED SYNTHESIS OF RIBONUCLEIC ACID BY AN ENZYME FROM ESCHERICHIA COLI , 1962 .
[51] W. Bailey. History of Vaccination. , 1899, Public health papers and reports.