Optimizing the Performance of Probabilistic Neural Networks in a BioinformaticsTa sk

A self adaptive probabilistic neural network model is proposed. The model incorporates the Particle Swarm Optimization algorithm to optimize the spread parameter of the probabilistic neural network, enhancing thus its perfor- mance. The proposed approach is tested on two data sets from the eld of bioinformatics, with promising results. The performance of the proposed model is compared to probabilistic neural networks, as well as to four different feedfor- ward neural networks. Different sampling techniques are used, and statistical tests are performed to justify the statistical signicance of the results.

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