The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873

[1]  M. Ibberson,et al.  Discovery and functional characterization of cardiovascular long noncoding RNAs. , 2015, Journal of molecular and cellular cardiology.

[2]  A. Bayoumi,et al.  Long Non-Coding RNAs as Master Regulators in Cardiovascular Diseases , 2015, International journal of molecular sciences.

[3]  C. Bauters,et al.  [Potential of non-coding RNA as biomarkers in heart failure]. , 2015, Medecine sciences : M/S.

[4]  Zhijian Yang,et al.  Altered long noncoding RNA expression profiles in the myocardium of rats with ischemic heart failure , 2015, Journal of cardiovascular medicine.

[5]  Yan Li,et al.  Interleukin-17 (IL-17)-induced MicroRNA 873 (miR-873) Contributes to the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting A20 Ubiquitin-editing Enzyme* , 2014, The Journal of Biological Chemistry.

[6]  Florian Reisinger,et al.  RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction. , 2014, Cardiovascular research.

[7]  A. Hergovich,et al.  The Hippo pathway in disease and therapy: cancer and beyond , 2014, Clinical and Translational Medicine.

[8]  Boris N. Kholodenko,et al.  Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling , 2014, Nature Cell Biology.

[9]  B. Rollins,et al.  Somatic activating ARAF mutations in Langerhans cell histiocytosis. , 2014, Blood.

[10]  M. Hermiston,et al.  A(nother) RAF mutation in LCH. , 2014, Blood.

[11]  W. Kolch,et al.  HGF induces epithelial-to-mesenchymal transition by modulating the mammalian hippo/MST2 and ISG15 pathways. , 2014, Journal of proteome research.

[12]  M. Meyerson,et al.  Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma. , 2014, The Journal of clinical investigation.

[13]  L. Zender,et al.  Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development , 2014, RNA.

[14]  Ling V. Sun,et al.  Mst1 and Mst2 Are Essential Regulators of Trophoblast Differentiation and Placenta Morphogenesis , 2014, PloS one.

[15]  S. Rahman,et al.  HTLV-1 Tax mediated downregulation of miRNAs associated with chromatin remodeling factors in T cells with stably integrated viral promoter , 2014, Retrovirology.

[16]  P. Vandenabeele,et al.  Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis , 2014, Cell Death and Disease.

[17]  D. Barford,et al.  KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation , 2013, Cell.

[18]  P. Yuan,et al.  Functional Role of Mst1/Mst2 in Embryonic Stem Cell Differentiation , 2013, PloS one.

[19]  Julian Downward,et al.  Hmga2 functions as a competing endogenous RNA to promote lung cancer progression , 2013, Nature.

[20]  F. Martín-Belmonte,et al.  Crossroads of Wnt and Hippo in epithelial tissues. , 2013, Trends in cell biology.

[21]  A. Penzo-Méndez,et al.  Hippo signaling regulates differentiation and maintenance in the exocrine pancreas. , 2013, Gastroenterology.

[22]  Shuji Takahashi,et al.  Hippo signaling components, Mst1 and Mst2, act as a switch between self-renewal and differentiation in Xenopus hematopoietic and endothelial progenitors. , 2013, International Journal of Developmental Biology.

[23]  David M. Thomas,et al.  The Hippo pathway and human cancer , 2013, Nature Reviews Cancer.

[24]  K. Guan,et al.  The Hippo pathway: regulators and regulations. , 2013, Genes & development.

[25]  Robert E. Lewis,et al.  Kinase Suppressor of Ras 2 (KSR2) Regulates Tumor Cell Transformation via AMPK , 2012, Molecular and Cellular Biology.

[26]  U. Moll,et al.  p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis , 2012, Cell.

[27]  Donncha F. O’Brien,et al.  Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects , 2012, Nature Medicine.

[28]  P. Doevendans,et al.  Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia–reperfusion in vivo , 2012, Basic Research in Cardiology.

[29]  Xiaodong Wang,et al.  Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase , 2012, Cell.

[30]  Chaoqian Xu,et al.  The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2 , 2011, Nature Medicine.

[31]  D. Cacchiarelli,et al.  A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA , 2011, Cell.

[32]  A. Meng,et al.  Angiomotin-like2 Gene (amotl2) Is Required for Migration and Proliferation of Endothelial Cells during Angiogenesis* , 2011, The Journal of Biological Chemistry.

[33]  Bryan R. Cullen,et al.  Reduced Expression of Brain-Enriched microRNAs in Glioblastomas Permits Targeted Regulation of a Cell Death Gene , 2011, PloS one.

[34]  D. Stolz,et al.  Characterization of DISC formation and TNFR1 translocation to mitochondria in TNF-α-treated hepatocytes. , 2011, The American journal of pathology.

[35]  T. Bale,et al.  Early Prenatal Stress Epigenetically Programs Dysmasculinization in Second-Generation Offspring via the Paternal Lineage , 2011, The Journal of Neuroscience.

[36]  C. Kanduri.  Kcnq1ot1: a chromatin regulatory RNA. , 2011, Seminars in cell & developmental biology.

[37]  J. Mattick,et al.  The melanoma-upregulated long noncoding RNA SPRY4-IT1 modulates apoptosis and invasion. , 2011, Cancer research.

[38]  L. V. Van Laake,et al.  miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes , 2011, The Journal of experimental medicine.

[39]  W. Kolch,et al.  Raf family kinases: old dogs have learned new tricks. , 2011, Genes & cancer.

[40]  Junjie Chen,et al.  Angiomotin-like Proteins Associate with and Negatively Regulate YAP1* , 2010, The Journal of Biological Chemistry.

[41]  L. Maquat,et al.  lncRNAs transactivate Staufen1-mediated mRNA decay by duplexing with 3'UTRs via Alu elements , 2010, Nature.

[42]  M. Medvedovic,et al.  MicroRNA-494 Targeting Both Proapoptotic and Antiapoptotic Proteins Protects Against Ischemia/Reperfusion-Induced Cardiac Injury , 2010, Circulation.

[43]  J. Steitz,et al.  Down-Regulation of a Host MicroRNA by a Herpesvirus saimiri Noncoding RNA , 2010, Science.

[44]  Jiayi Wang,et al.  CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer , 2010, Nucleic acids research.

[45]  Danish Sayed,et al.  MicroRNA-21 Is a Downstream Effector of AKT That Mediates Its Antiapoptotic Effects via Suppression of Fas Ligand* , 2010, The Journal of Biological Chemistry.

[46]  F. Chan,et al.  Physiological consequences of programmed necrosis, an alternative form of cell demise , 2010, Molecules and cells.

[47]  Peifeng Li.  MicroRNAs in Cardiac Apoptosis , 2010, Journal of cardiovascular translational research.

[48]  Howard Y. Chang,et al.  Long noncoding RNA HOTAIR reprograms chromatin state to promote cancer metastasis , 2010, Nature.

[49]  W. Kolch,et al.  Tumor and Stem Cell Biology Heterogeneous Nuclear Ribonucleoprotein H Blocks Mst2-mediated Apoptosis in Cancer Cells by Regulating A-raf Transcription , 2022 .

[50]  Robert E. Lewis,et al.  KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity. , 2009, Cell metabolism.

[51]  V. Rao,et al.  Proteomic characterization of the dynamic KSR-2 interactome, a signaling scaffold complex in MAPK pathway. , 2009, Biochimica et biophysica acta.

[52]  Jianqin Jiao,et al.  miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy , 2009, Proceedings of the National Academy of Sciences.

[53]  Na Zhang,et al.  RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis , 2009, Science.

[54]  T. Veenstra,et al.  KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals. , 2009, Molecular cell.

[55]  Tao Wang,et al.  Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α , 2009, Cell.

[56]  F. Chan,et al.  Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation , 2009, Cell.

[57]  J. Olson,et al.  DR5-mediated DISC controls caspase-8 cleavage and initiation of apoptosis in human glioblastomas , 2009, Journal of cellular and molecular medicine.

[58]  John N. Hutchinson,et al.  An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. , 2009, Molecular cell.

[59]  Victoria Sanz-Moreno,et al.  Ras Subcellular Localization Defines Extracellular Signal-Regulated Kinase 1 and 2 Substrate Specificity through Distinct Utilization of Scaffold Proteins , 2008, Molecular and Cellular Biology.

[60]  Jian Yu,et al.  PUMA, a potent killer with or without p53 , 2008, Oncogene.

[61]  W. Tan,et al.  Foxo3a Inhibits Cardiomyocyte Hypertrophy through Transactivating Catalase* , 2008, Journal of Biological Chemistry.

[62]  R. Zahedi,et al.  Positive Regulation of A-RAF by Phosphorylation of Isoform-specific Hinge Segment and Identification of Novel Phosphorylation Sites* , 2008, Journal of Biological Chemistry.

[63]  P. Zamore,et al.  Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells , 2008, Nature Protocols.

[64]  A. Pinto,et al.  Essential role of ERK dimers in the activation of cytoplasmic but not nuclear substrates by ERK-scaffold complexes. , 2008, Molecular cell.

[65]  Ru Wei,et al.  The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth , 2008, Nature.

[66]  P. Vandenabeele,et al.  Caspase-14 reveals its secrets , 2008, The Journal of cell biology.

[67]  J. Troppmair,et al.  Regulation of pyruvate kinase type M2 by A-Raf: a possible glycolytic stop or go mechanism. , 2007, Anticancer research.

[68]  Walter Kolch,et al.  RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein. , 2007, Molecular cell.

[69]  U. Rapp,et al.  Unique N-region Determines Low Basal Activity and Limited Inducibility of A-RAF Kinase , 2007, Journal of Biological Chemistry.

[70]  John H. White,et al.  Expression of human kinase suppressor of Ras 2 (hKSR-2) gene in HL60 leukemia cells is directly upregulated by 1,25-dihydroxyvitamin D(3) and is required for optimal cell differentiation. , 2007, Experimental cell research.

[71]  T. Takenawa,et al.  DA-Raf1, a competent intrinsic dominant-negative antagonist of the Ras–ERK pathway, is required for myogenic differentiation , 2007, The Journal of cell biology.

[72]  K. Chien,et al.  Molecular medicine: MicroRNAs and the tell-tale heart , 2007, Nature.

[73]  M. Basson.  MicroRNAs loom large in the heart , 2007, Nature Medicine.

[74]  J. Marín-García,et al.  Oxidative stress enhances phosphorylation of p53 in neonatal rat cardiomyocytes , 2007, Molecular and Cellular Biochemistry.

[75]  Michael T. McManus,et al.  Dysregulation of Cardiogenesis, Cardiac Conduction, and Cell Cycle in Mice Lacking miRNA-1-2 , 2007, Cell.

[76]  Thomas Thum,et al.  MicroRNAs in the Human Heart: A Clue to Fetal Gene Reprogramming in Heart Failure , 2007, Circulation.

[77]  Takashi Nakakuki,et al.  Quantitative transcriptional control of ErbB receptor signaling undergoes graded to biphasic response for cell differentiation. , 2006, The Journal of Biological Chemistry.

[78]  Sung Soo Kim,et al.  Differential anti-proliferative actions of peroxisome proliferator-activated receptor-gamma agonists in MCF-7 breast cancer cells. , 2006, Biochemical pharmacology.

[79]  M. Rijnkels,et al.  A noncoding RNA is a potential marker of cell fate during mammary gland development. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[80]  Robert E. Lewis,et al.  The Molecular Scaffold Kinase Suppressor of Ras 1 Is a Modifier of RasV12-Induced and Replicative Senescence , 2006, Molecular and Cellular Biology.

[81]  Z. Weng,et al.  A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome , 2006, Cell.

[82]  R. Seger,et al.  The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions , 2006, Growth factors.

[83]  A. Furukawa,et al.  H2O2 Accelerates Cellular Senescence by Accumulation of Acetylated p53 via Decrease in the Function of SIRT1 by NAD+ Depletion , 2006, Cellular Physiology and Biochemistry.

[84]  N. Rajewsky,et al.  Silencing of microRNAs in vivo with ‘antagomirs’ , 2005, Nature.

[85]  K. Livak,et al.  Real-time quantification of microRNAs by stem–loop RT–PCR , 2005, Nucleic acids research.

[86]  W. Kolch.  Coordinating ERK/MAPK signalling through scaffolds and inhibitors , 2005, Nature Reviews Molecular Cell Biology.

[87]  Y. Choi,et al.  Retroviral expression screening of oncogenes in pancreatic ductal carcinoma. , 2005, European journal of cancer.

[88]  Jeffrey Robbins,et al.  Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death , 2005, Nature.

[89]  Tetsuya Watanabe,et al.  Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death , 2005, Nature.

[90]  J. Alan,et al.  Protein Kinase C and Epidermal Growth Factor Stimulation of Raf1 Potentiates Adenylyl Cyclase Type 6 Activation in Intact Cells , 2005, Molecular Pharmacology.

[91]  Walter Kolch,et al.  Role of the Kinase MST2 in Suppression of Apoptosis by the Proto-Oncogene Product Raf-1 , 2004, Science.

[92]  Anna R Martirosyan,et al.  Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model. , 2004, Biochemical pharmacology.

[93]  B. Mack,et al.  Allogenic antibody-mediated identification of head and neck cancer antigens. , 2004, Biochemical and biophysical research communications.

[94]  Robert E. Lewis,et al.  The Molecular Scaffold KSR1 Regulates the Proliferative and Oncogenic Potential of Cells , 2004, Molecular and Cellular Biology.

[95]  M. Farrar,et al.  Membrane Localization, Oligomerization, and Phosphorylation Are Required for Optimal Raf Activation* , 2003, Journal of Biological Chemistry.

[96]  V. Kim,et al.  The nuclear RNase III Drosha initiates microRNA processing , 2003, Nature.

[97]  T. Veenstra,et al.  Protein Phosphatase 2A Positively Regulates Ras Signaling by Dephosphorylating KSR1 and Raf-1 on Critical 14-3-3 Binding Sites , 2003, Current Biology.

[98]  U. Rapp,et al.  Ras signaling: PP2A puts Ksr and Raf in the right place , 2003, Current Biology.

[99]  P. Bernardi,et al.  The selection between apoptosis and necrosis is differentially regulated in hydrogen peroxide-treated and glutathione-depleted human promonocytic cells , 2003, Cell Death and Differentiation.

[100]  R. Kolesnick,et al.  Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice. , 2003, Cancer research.

[101]  Yan-Hsiung Wang,et al.  Identification and Characterization of a Novel p300-mediated p53 Acetylation Site, Lysine 305* , 2003, Journal of Biological Chemistry.

[102]  M. Kelliher,et al.  The Death Domain Kinase RIP Protects Thymocytes from Tumor Necrosis Factor Receptor Type 2–induced Cell Death , 2002, The Journal of experimental medicine.

[103]  Kenneth M. Murphy,et al.  Kinase Suppressor of Ras (KSR) Is a Scaffold Which Facilitates Mitogen-Activated Protein Kinase Activation In Vivo , 2002, Molecular and Cellular Biology.

[104]  T. Schedl,et al.  C. elegans ksr-1 and ksr-2 Have Both Unique and Redundant Functions and Are Required for MPK-1 ERK Phosphorylation , 2002, Current Biology.

[105]  W. Dai,et al.  Reactive Oxygen Species-induced Phosphorylation of p53 on Serine 20 Is Mediated in Part by Polo-like Kinase-3* , 2001, The Journal of Biological Chemistry.

[106]  J. Hancock,et al.  Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions , 2001, Oncogene.

[107]  T. Ohyama,et al.  MST, a Physiological Caspase Substrate, Highly Sensitizes Apoptosis Both Upstream and Downstream of Caspase Activation* , 2001, The Journal of Biological Chemistry.

[108]  Brian Seed,et al.  Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule , 2000, Nature Immunology.

[109]  W. Kolch,et al.  Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation* , 2000, The Journal of Biological Chemistry.

[110]  A. Yuryev,et al.  Isoform-Specific Localization of A-RAF in Mitochondria , 2000, Molecular and Cellular Biology.

[111]  C. Herrmann,et al.  Mitogenic signaling of Ras is regulated by differential interaction with Raf isozymes , 2000, Oncogene.

[112]  R. von Harsdorf,et al.  p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c‐independent apoptosis blocked by Bcl‐2 , 1999, The EMBO journal.

[113]  C. di Loreto,et al.  Myocyte death in the failing human heart is gender dependent. , 1999, Circulation research.

[114]  M. Raff,et al.  Caspase activation in the terminal differentiation of human epidermal keratinocytes , 1999, Current Biology.

[115]  V. Rotter,et al.  Hydrogen peroxide induces nuclear translocation of p53 and apoptosis in cells of oligodendroglia origin. , 1999, Brain research. Molecular brain research.

[116]  H. Endou,et al.  Hydrogen Peroxide Induces Necrosis, Apoptosis, Oncosis and Apoptotic Oncosis of Mouse Terminal Proximal Straight Tubule Cells , 1999, Nephron.

[117]  J. McCubrey,et al.  Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells , 1998, Leukemia.

[118]  S. Ménard,et al.  Increased expression of c-erbB-2 in hormone-dependent breast cancer cells inhibits cell growth and induces differentiation , 1998, Oncogene.

[119]  W. Fiers,et al.  Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor , 1998, The Journal of experimental medicine.

[120]  E. Krebs,et al.  Caspase‐mediated activation and induction of apoptosis by the mammalian Ste20‐like kinase Mst1 , 1998, The EMBO journal.

[121]  R. Peshock,et al.  Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha. , 1998, Circulation.

[122]  C. Marshall,et al.  Differential Regulation of Raf-1, A-Raf, and B-Raf by Oncogenic Ras and Tyrosine Kinases* , 1997, The Journal of Biological Chemistry.

[123]  G. Rubin,et al.  KSR modulates signal propagation within the MAPK cascade. , 1996, Genes & development.

[124]  S. Schreiber,et al.  Controlling protein association and subcellular localization with a synthetic ligand that induces heterodimerization of proteins. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[125]  E. Lalani,et al.  bcl-2: role in epithelial differentiation and oncogenesis. , 1996, Human pathology.

[126]  C. Rommel,et al.  Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1. , 1996, Oncogene.

[127]  H. Horvitz,et al.  The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans , 1995, Cell.

[128]  Min Han,et al.  The C. elegans ksr-1 gene encodes a novel raf-related kinase involved in Ras-mediated signal transduction , 1995, Cell.

[129]  Henry C. Chang,et al.  KSR, a novel protein kinase required for RAS signal transduction , 1995, Cell.

[130]  C. Pritchard,et al.  Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells , 1995, Molecular and cellular biology.

[131]  J. Hancock,et al.  Activation of Raf as a result of recruitment to the plasma membrane. , 1994, Science.

[132]  Sally J. Leevers,et al.  Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane , 1994, Nature.

[133]  S. Elledge,et al.  Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1 , 1993, Nature.

[134]  M. Weber,et al.  Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase. , 1993, Science.

[135]  Paul W. Sternberg,et al.  C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation , 1993, Nature.

[136]  S. Barni,et al.  Enhanced secretion of tumour necrosis factor in patients with myocardial infarction. , 1992, European Journal of Medicine.

[137]  R. Lupu,et al.  A ligand for the erbB-2 oncogene product (gp30) induces differentiation of human breast cancer cells. , 1992, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[138]  J. Cohen,et al.  Programmed cell death in terminally differentiating keratinocytes: role of endogenous endonuclease. , 1991, The Journal of investigative dermatology.

[139]  N. Gas,et al.  Effects of differentiation‐inducing agents on maturation of human MCF‐7 breast cancer cells , 1990, Journal of cellular physiology.

[140]  G. Gould,et al.  Expression of c-raf-1 and A-raf-1 during differentiation of 3T3-L1 preadipocyte fibroblasts into adipocytes. , 1989, Biochemical and biophysical research communications.

[141]  S. Hsu,et al.  The use of antiavidin antibody and avidin-biotin-peroxidase complex in immunoperoxidase technics. , 1981, American journal of clinical pathology.

[142]  Yanrui Li,et al.  miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1 , 2011, Nature Medicine.

[143]  K. Guan,et al.  Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. , 2011, Genes & development.

[144]  S. Dimmeler,et al.  Control of cardiovascular differentiation by microRNAs , 2010, Basic Research in Cardiology.

[145]  U. Rapp,et al.  RAF expression in human astrocytic tumors. , 2009, International journal of molecular medicine.

[146]  P. Vandenabeele,et al.  Caspases in cell survival, proliferation and differentiation , 2007, Cell Death and Differentiation.

[147]  寺井 健太.  Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase , 2006 .

[148]  S. Schreiber,et al.  Dimerization as a regulatory mechanism in signal transduction. , 1998, Annual review of immunology.

[149]  A. Lichtenstein,et al.  Apoptotic vs. nonapoptotic cytotoxicity induced by hydrogen peroxide. , 1997, Free radical biology & medicine.

[150]  D. Yellon,et al.  Inability of dimethylthiourea to limit tissue necrosis during acute myocardial infarction in rabbits. , 1992, Free radical biology & medicine.

[151]  J. Downey,et al.  Free radicals and their involvement during long-term myocardial ischemia and reperfusion. , 1990, Annual review of physiology.