Rheologic properties of soft tissue fillers and implications for clinical use

The use of injectable soft‐tissue fillers has become an essential tool in esthetic rejuvenation. Rheology, the study of flow of matter, helps to understand the function of these products.

[1]  D. Cassuto,et al.  Biophysical Characteristics of Hyaluronic Acid Soft-Tissue Fillers and Their Relevance to Aesthetic Applications , 2013, Plastic and reconstructive surgery.

[2]  S. Manfredini,et al.  Hyaluronic Acid Fillers in Soft Tissue Regeneration , 2017, Facial Plastic Surgery.

[3]  K. Arndt,et al.  Delayed-Onset Nodules to Differentially Crosslinked Hyaluronic Acids: Comparative Incidence and Risk Assessment. , 2019, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[4]  G. Lemperle,et al.  ArteFill: a third-generation permanent dermal filler and tissue stimulator. , 2006, Clinics in plastic surgery.

[5]  A. Swift,et al.  Minimal recovery time needed to return to social engagement following nasolabial fold correction with hyaluronic acid fillers produced with XpresHAn technology , 2017, Clinical, cosmetic and investigational dermatology.

[6]  L. Baumann,et al.  A double-blind, randomized, multicenter, controlled trial of suspended polymethylmethacrylate microspheres for the correction of atrophic facial acne scars. , 2014, Journal of the American Academy of Dermatology.

[7]  D. Vleggaar,et al.  Composition and mechanism of action of poly-L-lactic acid in soft tissue augmentation. , 2014, Journal of Drugs in Dermatology.

[8]  T. Michaud Rheology of hyaluronic acid and dynamic facial rejuvenation: Topographical specificities , 2018, Journal of cosmetic dermatology.

[9]  M. A. O. Ignacio,et al.  How to cite this article , 2016 .

[10]  Darin J. Messina,et al.  Rheological Properties and In Vivo Performance Characteristics of Soft Tissue Fillers , 2015, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[11]  C. Murray,et al.  The evolution of soft tissue fillers in clinical practice. , 2005, Dermatologic clinics.

[12]  James Varani,et al.  In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin. , 2007, Archives of dermatology.

[13]  S. Vogt,et al.  A Multicenter, Randomized Trial Comparing Calcium Hydroxylapatite to Two Hyaluronic Acids for Treatment of Nasolabial Folds , 2007, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[14]  J. Carruthers,et al.  Volumizing with a 20‐mg/mL Smooth, Highly Cohesive, Viscous Hyaluronic Acid Filler and Its Role in Facial Rejuvenation Therapy , 2010, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[15]  Alexander Zinovy Rivkin A Prospective Study of Non‐Surgical Primary Rhinoplasty Using a Polymethylmethacrylate Injectable Implant , 2014, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[16]  G. Lemperle,et al.  Soft Tissue Augmentation With Artecoll: 10‐Year History, Indications, Techniques, and Complications , 2003, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[17]  T. Flynn,et al.  Hyaluronic Acids: Clinical Applications , 2010 .

[18]  M. Bothwell,et al.  Novel use of polymethyl methacrylate (PMMA) microspheres in the treatment of infraorbital rhytids , 2013, Journal of cosmetic dermatology.

[19]  J. Dover,et al.  Five-Year Safety and Satisfaction Study of PMMA–Collagen in the Correction of Nasolabial Folds , 2015, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[20]  Glenn H Fredrickson,et al.  The science of hyaluronic acid dermal fillers , 2008, Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology.

[21]  Rod J. Rohrich,et al.  Cohesivity of Hyaluronic Acid Fillers: Development and Clinical Implications of a Novel Assay, Pilot Validation with a Five-Point Grading Scale, and Evaluation of Six U.S. Food and Drug Administration–Approved Fillers , 2015, Plastic and reconstructive surgery.

[22]  S. Liew,et al.  Basics of Dermal Filler Rheology , 2015, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[23]  Hema Sundaram,et al.  Comparison of the Rheological Properties of Viscosity and Elasticity in Two Categories of Soft Tissue Fillers: Calcium Hydroxylapatite and Hyaluronic Acid , 2010, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[24]  G. Monheit,et al.  Comparative Physical Properties of Hyaluronic Acid Dermal Fillers , 2009, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[25]  V. Bertucci,et al.  Rheologic and Physicochemical Properties Used to Differentiate Injectable Hyaluronic Acid Filler Products , 2019, Plastic and reconstructive surgery.

[26]  N. Sadick,et al.  ArteFill® Permanent Injectable for Soft Tissue Augmentation: I. Mechanism of Action and Injection Techniques , 2009, Aesthetic Plastic Surgery.

[27]  C. Bayerl,et al.  Efficacy and safety of a new hyaluronic acid dermal filler in the treatment of moderate nasolabial folds: 6-month interim results of a randomized, evaluator-blinded, intra-individual comparison study , 2011, Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology.

[28]  N. Sadick,et al.  Optimizing outcomes with polymethylmethacrylate fillers , 2018, Journal of cosmetic dermatology.

[29]  G. Lemperle,et al.  Foreign Body Granulomas after All Injectable Dermal Fillers: Part 2. Treatment Options , 2009, Plastic and reconstructive surgery.

[30]  D. Vleggaar,et al.  Facial volume restoration of the aging face with poly‐l‐lactic acid , 2011, Dermatologic therapy.

[31]  D. Goldberg,et al.  Calcium Hydroxylapatite Filler for Facial Rejuvenation: A Histologic and Immunohistochemical Analysis , 2008, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[32]  Rod J. Rohrich,et al.  A randomized study of the efficacy and safety of injectable poly-L-lactic acid versus human-based collagen implant in the treatment of nasolabial fold wrinkles. , 2010, Journal of the American Academy of Dermatology.

[33]  Kevin C. Smith,et al.  Five percent lidocaine cream applied simultaneously to the skin and mucosa of the lips creates excellent anesthesia for filler injections. , 2005, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[34]  D. Hurwitz,et al.  Malar augmentation with a polymethylmethacrylate-enhanced filler: assessment of a 12-month open-label pilot study. , 2013, Aesthetic surgery journal.

[35]  D. Vleggaar Facial volumetric correction with injectable poly-L-lactic acid. , 2005, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[36]  S. Dahan,et al.  Association between collagen production and mechanical stretching in dermal extracellular matrix: in vivo effect of cross-linked hyaluronic acid filler. A randomised, placebo-controlled study. , 2013, Journal of dermatological science.

[37]  Derek H. Jones Injectable Fillers: Principles and Practice , 2010 .

[38]  J. Carruthers,et al.  Fillers and Neocollagenesis , 2014, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[39]  G. Lemperle,et al.  Foreign Body Granulomas after All Injectable Dermal Fillers: Part 1. Possible Causes , 2009, Plastic and reconstructive surgery.

[40]  V. Bertucci,et al.  Dynamics of hyaluronic acid fillers formulated to maintain natural facial expression , 2019, Journal of cosmetic dermatology.

[41]  D. Goldberg,et al.  Physiochemical Characteristics of Poly-L-Lactic Acid (PLLA) , 2018, Aesthetic surgery journal.

[42]  A. Breithaupt,et al.  Collagen Stimulators: Poly-L-Lactic Acid and Calcium Hydroxyl Apatite. , 2015, Facial plastic surgery clinics of North America.