A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

[1]  S. Tonegawa,et al.  Expression of cloned immunoglobulin genes introduced into mouse L cells. , 1983, Nucleic acids research.

[2]  S. Tonegawa.  Somatic generation of antibody diversity , 1983, Nature.

[3]  P. Gruss,et al.  Multiple point mutations affecting the simian virus 40 enhancer. , 1983, Science.

[4]  G. Klein.  Specific chromosomal translocations and the genesis of B-cell-derived tumors in mice and men , 1983, Cell.

[5]  P. Chambon,et al.  The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements , 1983, Cell.

[6]  S. Morrison,et al.  Immunoglobulin gene expression in transformed lymphoid cells. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[7]  J. Goverman,et al.  An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell development. , 1982, Nucleic acids research.

[8]  D. Baltimore,et al.  Regulated expression of an immunoglobulin kappa gene introduced into a mouse lymphoid cell line. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[9]  P. Gruss,et al.  Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[10]  D. Granner,et al.  Chromatin changes accompany immunoglobulin κ gene activation: a potential control region within the gene , 1982, Nature.

[11]  B. Howard,et al.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells , 1982, Molecular and cellular biology.

[12]  M. Botchan,et al.  Isolation and characterization of human DNA fragments with nucleotide sequence homologies with the simian virus 40 regulatory region , 1982, Molecular and cellular biology.

[13]  F. Alt,et al.  Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line , 1982, Nature.

[14]  E. Linney,et al.  Polyoma mutants that productively infect F9 embryonal carcinoma cells do not rescue wild-type polyoma in F9 cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[15]  P. Gruss,et al.  Activation of SV40 genome by 72-base pair tandem repeats of Moloney sarcoma virus , 1982, Nature.

[16]  H. Varmus,et al.  Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas , 1982, Nature.

[17]  R. Perry,et al.  Transcriptional regulation of immunoglobulin V genes. , 1981, Nucleic acids research.

[18]  W. Schaffner,et al.  A small segment of polyoma virus DNA enhances the expression of a cloned beta-globin gene over a distance of 1400 base pairs. , 1981, Nucleic acids research.

[19]  B. Ness,et al.  Transcription of the unrearranged mouse Cκ locus: Sequence of the initiation region and comparison of activity with a rearranged Vκ-Cκ gene , 1981, Cell.

[20]  J. Banerji,et al.  Expression of a β-globin gene is enhanced by remote SV40 DNA sequences , 1981, Cell.

[21]  Mark M. Davis,et al.  Antibody diversity: Somatic hypermutation of rearranged VH genes , 1981, Cell.

[22]  P. Chambon,et al.  The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants. , 1981, Nucleic acids research.

[23]  E. Selsing,et al.  Mapping of immunoglobulin variable region genes: relationship to the 'deletion' model of immunoglobulin gene rearrangement. , 1981, Nucleic acids research.

[24]  I. Verma,et al.  Nucleotide sequence of the genome of a murine sarcoma virus , 1981, Cell.

[25]  A. L. Goldin,et al.  High-frequency transfer of cloned herpes simplex virus type 1 sequences to mammalian cells by protoplast fusion. , 1981, Molecular and cellular biology.

[26]  J V Maizel,et al.  The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes. , 1981, The Journal of biological chemistry.

[27]  W. S. Hayward,et al.  Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis , 1981, Nature.

[28]  E. Linney,et al.  Mutation near the polyoma DNA replication origin permits productive infection of F9 embryonal carcinoma cells , 1981, Cell.

[29]  H. Varmus,et al.  Analysis of avian leukosis virus DNA and RNA in bursal tumors: Viral gene expression is not required for maintenance of the tumor state , 1981, Cell.

[30]  R. Mulligan,et al.  Expression of a bacterial gene in mammalian cells. , 1980, Science.

[31]  Hitoshi Sakano,et al.  Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes , 1980, Nature.

[32]  M. Yaniv,et al.  Expression of polyoma early functions in mouse embryonal carcinoma cells depends on sequence rearrangements in the beginning of the late region , 1980, Cell.

[33]  D. Kemp,et al.  Expression of the immunoglobulin C mu gene in mouse T and B lymphoid and myeloid cell lines. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[34]  S. Tonegawa,et al.  Exon shuffling generates an immunoglobulin heavy chain gene. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[35]  L. Hood,et al.  An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH , 1980, Cell.

[36]  M. Cooper,et al.  Mouse pre-B cells synthesize and secrete μ heavy chains but not light chains , 1980, Cell.

[37]  Mark M. Davis,et al.  An immunoglobulin heavy-chain gene is formed by at least two recombinational events , 1980, Nature.

[38]  T. Honjo,et al.  Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[39]  J. Bishop,et al.  DNA and RNA from Uninfected Vertebrate Cells Contain Nucleotide Sequences Related to the Putative Transforming Gene of Avian Myelocytomatosis Virus , 1979, Journal of virology.

[40]  Hitoshi Sakano,et al.  Sequences at the somatic recombination sites of immunoglobulin light-chain genes , 1979, Nature.

[41]  J. Seidman,et al.  Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[42]  U. Schibler,et al.  The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells , 1978, Cell.

[43]  S. Tonegawa,et al.  Sequences of mouse immunoglobulin light chain genes before and after somatic changes , 1978, Cell.

[44]  Susumu Tonegawa,et al.  A complete immunoglobulin gene is created by somatic recombination , 1978, Cell.

[45]  W. Gilbert,et al.  Sequencing end-labeled DNA with base-specific chemical cleavages. , 1980, Methods in enzymology.

[46]  M. Weigert,et al.  Genetic control of antibody variable regions. , 1977, Cold Spring Harbor symposia on quantitative biology.