Diversity in Cortical Thymic Epithelial Cells Occurs through Loss of a Foxn1-Dependent Gene Signature Driven by Stage-Specific Thymocyte Cross-Talk
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S. Parnell | G. Anderson | S. Maio | A. Handel | G. Hollander | A. Bacon | B. Lucas | Emilie J. Cosway | Kieran D. James | W. Jenkinson | J. Cowan | Andrea J. White | Stefano Maio
[1] L. Klein,et al. LAMP2 regulates autophagy in the thymic epithelium and thymic stroma-dependent CD4 T cell development , 2022, Autophagy.
[2] Y. Takahama,et al. Peptides for T cell selection in the thymus , 2021, Peptides.
[3] K. Pham,et al. Developing T cells form an immunological synapse for passage through the β-selection checkpoint , 2021, The Journal of cell biology.
[4] Jianxun Han,et al. A 2020 View of Thymus Stromal Cells in T Cell Development , 2021, The Journal of Immunology.
[5] Y. Takahama,et al. Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells , 2020, Nature Communications.
[6] J. Marioni,et al. Ageing compromises mouse thymus function and remodels epithelial cell differentiation , 2020, bioRxiv.
[7] J. Abramson,et al. Thymic epithelial cell heterogeneity: TEC by TEC , 2019, Nature Reviews Immunology.
[8] J. Zúñiga-Pflücker,et al. RBPJ-dependent Notch signaling initiates the T cell program in a subset of thymus-seeding progenitors , 2019, Nature Immunology.
[9] K. Pham,et al. Developing T cells form an immunological synapse for passage through the β−selection checkpoint , 2019, bioRxiv.
[10] Graham Anderson,et al. Generation of diversity in thymic epithelial cells , 2017, Nature Reviews Immunology.
[11] Y. Nishito,et al. Foxn1-β5t transcriptional axis controls CD8+ T-cell production in the thymus , 2017, Nature Communications.
[12] R. Boyd,et al. A novel Foxn1eGFP/+ mouse model identifies Bmp4‐induced maintenance of Foxn1 expression and thymic epithelial progenitor populations , 2017, European journal of immunology.
[13] C. Ponting,et al. Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells , 2016, Nature Immunology.
[14] Kathy E. O’Neill,et al. Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution , 2016, PloS one.
[15] H. Rodewald,et al. Foxn1 Protein Expression in the Developing, Aging, and Regenerating Thymus , 2015, The Journal of Immunology.
[16] S. Jameson,et al. TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8+ T cells , 2015, Nature Immunology.
[17] S. Parnell,et al. Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development , 2015, The Journal of Immunology.
[18] Keiji Tanaka,et al. Thymoproteasomes produce unique peptide motifs for positive selection of CD8+ T cells , 2015, Nature Communications.
[19] J. Gordon,et al. Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus. , 2014, Immunity.
[20] Paul Theodor Pyl,et al. HTSeq—a Python framework to work with high-throughput sequencing data , 2014, bioRxiv.
[21] Björn Usadel,et al. Trimmomatic: a flexible trimmer for Illumina sequence data , 2014, Bioinform..
[22] J. Caamaño,et al. The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development , 2013, The Journal of experimental medicine.
[23] S. Morrison,et al. Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches , 2013, Nature.
[24] Guangchuang Yu,et al. clusterProfiler: an R package for comparing biological themes among gene clusters. , 2012, Omics : a journal of integrative biology.
[25] C. Nguyen,et al. Transcription profiling of Prss16 (Tssp) can be used to find additional peptidase genes that are candidates for self-peptide generation in the thymus , 2012, Molecular Biology Reports.
[26] J. Caamaño,et al. Lymphotoxin Signals from Positively Selected Thymocytes Regulate the Terminal Differentiation of Medullary Thymic Epithelial Cells , 2010, The Journal of Immunology.
[27] M. Janas,et al. Stromal cell-derived factor 1α and CXCR4: newly defined requirements for efficient thymic β-selection. , 2010, Trends in immunology.
[28] T. Boehm,et al. Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage , 2010, Proceedings of the National Academy of Sciences.
[29] M. Turner,et al. Thymic development beyond β-selection requires phosphatidylinositol 3-kinase activation by CXCR4 , 2010, The Journal of experimental medicine.
[30] D. Littman,et al. CXCR4 acts as a costimulator during thymic β selection , 2009, Nature Immunology.
[31] Mark D. Robinson,et al. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..
[32] L. Davis,et al. Cutting Edge: Thymic Crosstalk Regulates Delta-Like 4 Expression on Cortical Epithelial Cells1 , 2008, The Journal of Immunology.
[33] N. Manley,et al. Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment , 2008, The Journal of experimental medicine.
[34] H. Takayanagi,et al. The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. , 2008, Immunity.
[35] N. Manley,et al. Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus , 2007, BMC Developmental Biology.
[36] J. Penninger,et al. RANK signals from CD4+3− inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla , 2007, The Journal of Experimental Medicine.
[37] Keiji Tanaka,et al. Regulation of CD8+ T Cell Development by Thymus-Specific Proteasomes , 2007, Science.
[38] H. Petrie,et al. Zoned out: functional mapping of stromal signaling microenvironments in the thymus. , 2007, Annual review of immunology.
[39] J. Pongrácz,et al. Modeling TCR Signaling Complex Formation in Positive Selection 1 , 2003, The Journal of Immunology.
[40] Christoph Peters,et al. Cathepsin L Regulates CD4+ T Cell Selection Independently of Its Effect on Invariant Chain , 2002, The Journal of experimental medicine.
[41] K. Rajewsky,et al. Homeostasis of Peripheral B Cells in the Absence of B Cell Influx from the Bone Marrow , 2001, The Journal of experimental medicine.
[42] Shankar Srinivas,et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus , 2001, BMC Developmental Biology.
[43] G. Morahan,et al. The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[44] Thomas Boehm,et al. New member of the winged-helix protein family disrupted in mouse and rat nude mutations , 1994, Nature.
[45] A. Singer,et al. Crosstalk in the mouse thymus. , 1994, Immunology today.
[46] G. Anderson,et al. MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus , 1993, Nature.
[47] S. Tonegawa,et al. Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages , 1992, Nature.
[48] G. Anderson,et al. Studies on T cell maturation on defined thymic stromal cell populations in vitro , 1992, The Journal of experimental medicine.
[49] A. Singer,et al. Disorganization and restoration of thymic medullary epithelial cells in T cell receptor‐negative scid mice: Evidence that receptor‐bearing lymphocytes influence maturation of the thymic microenvironment , 1991, European journal of immunology.
[50] J. Sprent,et al. T Cell Selection in the Thymus , 1988, Immunological reviews.
[51] R. Auerbach,et al. Inductive interaction of embryonic tissues after dissociation and reaggregation. , 1958, Experimental cell research.
[52] Thomas R. Gingeras,et al. STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..