Clinical problem-solving. Bitter pills.

Copyright © 2010 Massachusetts Medical Society. A 60-year-old man presented to an urgent care clinic with fatigue of 1 month’s duration and increasing frequency of urination, nighttime urination, and increasing thirst over the previous week. He had earlier been told that he had prediabetes and was now concerned that his symptoms reflected progression to diabetes mellitus. He was otherwise in his usual state of health. He reported no dysuria, urgency, incomplete bladder emptying, straining to initiate urination, fevers, chills, arthralgias, or rash.

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