Recent progress on the effect of extracellular matrix on occurrence and progression of breast cancer.

[1]  M. Posner.  Collagen type XII linked with poor overall survival in breast cancer , 2023, Cancer.

[2]  Chen Li,et al.  COL11A1 as an novel biomarker for breast cancer with machine learning and immunohistochemistry validation , 2022, Frontiers in Immunology.

[3]  H. McCarthy,et al.  Development and characterisation of 3D collagen-gelatin based scaffolds for breast cancer research. , 2022, Biomaterials advances.

[4]  K. Kim,et al.  Contribution of mechanical homeostasis to epithelial-mesenchymal transition. , 2022, Cellular oncology.

[5]  Y. Zhou,et al.  Correction: In situ monitoring of functional activity of extracellular matrix stiffness-dependent multidrug resistance protein 1 using scanning electrochemical microscopy , 2022, Chemical science.

[6]  Sean X. Sun,et al.  The interplay between physical cues and mechanosensitive ion channels in cancer metastasis , 2022, Frontiers in Cell and Developmental Biology.

[7]  M. Opyrchal,et al.  Mechano-Sensing Channel PIEZO2 Enhances Invasive Phenotype in Triple-Negative Breast Cancer , 2022, International journal of molecular sciences.

[8]  J. West,et al.  Tunable PEG Hydrogels for Discerning Differential Tumor Cell Response to Biomechanical Cues , 2022, Advanced biology.

[9]  Fan Yang,et al.  Silencing of COL3A1 represses proliferation, migration, invasion, and immune escape of triple negative breast cancer cells via down‐regulating PD‐L1 expression , 2022, Cell biology international.

[10]  J. Saez-Rodriguez,et al.  Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix , 2022, Nature Metabolism.

[11]  D. Yin,et al.  MiR-4458-loaded gelatin nanospheres target COL11A1 for DDR2/SRC signaling pathway inactivation to suppress the progression of estrogen receptor-positive breast cancer. , 2022, Biomaterials science.

[12]  Gang Zhao,et al.  Exosomes deliver lncRNA DARS-AS1 siRNA to inhibit chronic unpredictable mild stress-induced TNBC metastasis. , 2022, Cancer letters.

[13]  Y. Kato,et al.  COL8A1 facilitates the growth of triple-negative breast cancer via FAK/Src activation , 2022, Breast Cancer Research and Treatment.

[14]  L. Kiesel,et al.  The heparan sulphate proteoglycan Syndecan‐1 (CD138) regulates tumour progression in a 3D model of ductal carcinoma in situ of the breast , 2022, IUBMB life.

[15]  P. Rameshwar,et al.  Oncobiology and treatment of breast cancer in young women , 2022, Cancer and Metastasis Reviews.

[16]  G. Calin,et al.  Serglycin Is Involved in TGF-β Induced Epithelial-Mesenchymal Transition and Is Highly Expressed by Immune Cells in Breast Cancer Tissue , 2022, Frontiers in Oncology.

[17]  H. Hua,et al.  Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy , 2022, Journal of Hematology & Oncology.

[18]  P. V. van Diest,et al.  Spatial collagen stiffening promotes collective breast cancer cell invasion by reinforcing extracellular matrix alignment , 2022, Oncogene.

[19]  P. Olczyk,et al.  The Role of Extracellular Matrix Proteins in Breast Cancer , 2022, Journal of clinical medicine.

[20]  J. Bielas,et al.  Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain , 2021, Nature Cancer.

[21]  Min Chen,et al.  Integrin α6β4 requires plectin and vimentin for adhesion complex distribution and invasive growth. , 2021, Journal of cell science.

[22]  X. Kong,et al.  Recent Advances in the Role of Discoidin Domain Receptor Tyrosine Kinase 1 and Discoidin Domain Receptor Tyrosine Kinase 2 in Breast and Ovarian Cancer , 2021, Frontiers in Cell and Developmental Biology.

[23]  F. Giesel,et al.  Radioligands Targeting Fibroblast Activation Protein (FAP) , 2021, Cancers.

[24]  Tingting Li,et al.  Non-muscle myosin II isoforms orchestrate substrate stiffness sensing to promote cancer cell contractility and migration. , 2021, Cancer letters.

[25]  Jacob M. Hope,et al.  Channeling the Force: Piezo1 Mechanotransduction in Cancer Metastasis , 2021, Cells.

[26]  E. Turley,et al.  Hyaluronan Functions in Wound Repair That Are Captured to Fuel Breast Cancer Progression , 2021, Biomolecules.

[27]  S. Sen,et al.  ECM stiffness-tuned exosomes drive breast cancer motility through thrombospondin-1. , 2021, Biomaterials.

[28]  I. Miinalainen,et al.  Deletion of Col15a1 Modulates the Tumour Extracellular Matrix and Leads to Increased Tumour Growth in the MMTV-PyMT Mouse Mammary Carcinoma Model , 2021, International journal of molecular sciences.

[29]  C. Tanikawa,et al.  Collagen XVII inhibits breast cancer cell proliferation and growth through deactivation of the AKT/mTOR signaling pathway , 2021, PloS one.

[30]  C. Kuperwasser,et al.  Microenvironmental control of cell fate decisions in mammary gland development and cancer. , 2021, Developmental cell.

[31]  Shuibin Lin,et al.  Heterogeneous microenvironmental stiffness regulates pro-metastatic functions of breast cancer cells. , 2021, Acta biomaterialia.

[32]  M. Boutros,et al.  The extracellular matrix proteins type I collagen, type III collagen, fibronectin, and laminin 421 stimulate migration of cancer cells , 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[33]  Junmin Qian,et al.  Hydroxyethyl chitosan hydrogels for enhancing breast cancer cell tumorigenesis. , 2021, International journal of biological macromolecules.

[34]  S. Rangappa,et al.  New Heparanase-Inhibiting Triazolo-Thiadiazoles Attenuate Primary Tumor Growth and Metastasis , 2021, Cancers.

[35]  F. Gao,et al.  Hyaluronan synthase 2 (HAS2) regulates cell phenotype and invadopodia formation in luminal-like breast cancer cells , 2021, Molecular and Cellular Biochemistry.

[36]  Zihua Chen,et al.  EphA2–YES1–ANXA2 pathway promotes gastric cancer progression and metastasis , 2021, Oncogene.

[37]  Yongquan Zheng,et al.  Extracellular Matrix: Emerging Roles and Potential Therapeutic Targets for Breast Cancer , 2021, Frontiers in Oncology.

[38]  R. Steward,et al.  Evaluation of the effect of 3D porous Chitosan-alginate scaffold stiffness on breast cancer proliferation and migration. , 2021, Journal of biomedical materials research. Part A.

[39]  Catherine C. Park,et al.  Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer , 2021, The Journal of experimental medicine.

[40]  D. Waisman,et al.  Plasmin and Plasminogen System in the Tumor Microenvironment: Implications for Cancer Diagnosis, Prognosis, and Therapy , 2021, Cancers.

[41]  J. Couchman.  Syndecan-1 (CD138), Carcinomas and EMT , 2021, International journal of molecular sciences.

[42]  L. Haupt,et al.  Corrigendum: Heparanase Promotes Syndecan-1 Expression to Mediate Fibrillar Collagen and Mammographic Density in Human Breast Tissue Cultured ex vivo , 2021, Frontiers in Cell and Developmental Biology.

[43]  P. Vermeulen,et al.  Type IV collagen as a potential biomarker of metastatic breast cancer , 2021, Clinical & Experimental Metastasis.

[44]  K. Kyriakopoulou,et al.  Key Matrix Remodeling Enzymes: Functions and Targeting in Cancer , 2021, Cancers.

[45]  Youn-Jae Kim,et al.  RhoBTB3 Regulates Proliferation and Invasion of Breast Cancer Cells via Col1a1 , 2021, Molecules and cells.

[46]  Kalin L. Wilson,et al.  Oncogenic Functions and Therapeutic Targeting of EphA2 in Cancer , 2021, Oncogene.

[47]  Y. Lv,et al.  Three-dimensional decellularized tumor extracellular matrices with different stiffness as bioengineered tumor scaffolds , 2021, Bioactive materials.

[48]  V. Tzelepi,et al.  Epigenetic Alterations in Triple-Negative Breast Cancer—The Critical Role of Extracellular Matrix , 2021, Cancers.

[49]  Hassan Yousefi,et al.  Understanding the role of integrins in breast cancer invasion, metastasis, angiogenesis, and drug resistance , 2021, Oncogene.

[50]  K. Pantel,et al.  Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions , 2021, Oncogene.

[51]  M. V. Van Dyke,et al.  Collagen/kerateine multi-protein hydrogels as a thermally stable extracellular matrix for 3D in vitro models , 2021, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[52]  S. Niland,et al.  Hold on or Cut? Integrin- and MMP-Mediated Cell–Matrix Interactions in the Tumor Microenvironment , 2020, International journal of molecular sciences.

[53]  Xuan Wu,et al.  Collagen Type X Alpha 1 (COL10A1) Contributes to Cell Proliferation, Migration, and Invasion by Targeting Prolyl 4-Hydroxylase Beta Polypeptide (P4HB) in Breast Cancer , 2020, Medical science monitor : international medical journal of experimental and clinical research.

[54]  K. Shen,et al.  Breast Subtypes and Prognosis of Breast Cancer Patients With Initial Bone Metastasis: A Population-Based Study , 2020, Frontiers in Oncology.

[55]  Hongmei Zhou,et al.  Transforming Growth Factor-β Signaling in Fibrotic Diseases and Cancer-Associated Fibroblasts , 2020, Biomolecules.

[56]  Yu-han Qiu,et al.  Transcriptional co-activators YAP/TAZ: Potential therapeutic targets for metastatic breast cancer. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[57]  A. McGuigan,et al.  Matrix Stiffness-Regulated Growth of Breast Tumor Spheroids and Their Response to Chemotherapy. , 2020, Biomacromolecules.

[58]  L. Coussens,et al.  Tumor-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression , 2020, Nature Materials.

[59]  L. Haupt,et al.  Three-Dimensional Models as a New Frontier for Studying the Role of Proteoglycans in the Normal and Malignant Breast Microenvironment , 2020, Frontiers in Cell and Developmental Biology.

[60]  R. Haag,et al.  Tumor Microenvironment‐Activatable Nanoenzymes for Mechanical Remodeling of Extracellular Matrix and Enhanced Tumor Chemotherapy , 2020, Advanced Functional Materials.

[61]  Yueqing Gu,et al.  The improved targeting of an aspirin prodrug albumin-based nanosystem for visualizing and inhibiting lung metastasis of breast cancer. , 2020, Biomaterials science.

[62]  C. Lim,et al.  Cell Migration and Breast Cancer Metastasis in Biomimetic Extracellular Matrices with Independently Tunable Stiffness , 2020, Advanced Functional Materials.

[63]  S. Tojkander,et al.  TRPV6 calcium channel directs homeostasis of the mammary epithelial sheets and controls epithelial mesenchymal transition , 2020, Scientific Reports.

[64]  M. Franchi,et al.  Extracellular Matrix-Mediated Breast Cancer Cells Morphological Alterations, Invasiveness, and Microvesicles/Exosomes Release , 2020, Cells.

[65]  F. Saltel,et al.  A Complex and Evolutive Character: Two Face Aspects of ECM in Tumor Progression , 2020, Frontiers in Oncology.

[66]  B. Teicher.  TGFβ-Directed Therapeutics: 2020. , 2020, Pharmacology & therapeutics.

[67]  L. Bond,et al.  Novel mechanism for OSM-promoted extracellular matrix remodeling in breast cancer: LOXL2 upregulation and subsequent ECM alignment , 2020, Breast cancer research : BCR.

[68]  F. Saltel,et al.  Linking Matrix Rigidity with EMT and Cancer Invasion. , 2020, Developmental cell.

[69]  P. Kiely,et al.  Collagen and fibronectin promote an aggressive cancer phenotype in breast cancer cells but drive autonomous gene expression patterns. , 2020, Gene.

[70]  Zheng-Rong Lu,et al.  Overexpression of Extradomain-B Fibronectin is Associated with Invasion of Breast Cancer Cells , 2020, Cells.

[71]  Suaib Luqman,et al.  Isothymusin, a potential inhibitor of cancer cell proliferation: An in silico and in vitro investigation. , 2020, Current topics in medicinal chemistry.

[72]  Wenzhong Li,et al.  Matrix Stiffness Regulates Chemosensitivity, Stemness Characteristics, and Autophagy in Breast Cancer Cells , 2020 .

[73]  L. Haupt,et al.  Heparanase Promotes Syndecan-1 Expression to Mediate Fibrillar Collagen and Mammographic Density in Human Breast Tissue Cultured ex vivo , 2020, bioRxiv.

[74]  Fei Li,et al.  Effect of three-dimensional ECM stiffness on cancer cell migration through regulating cell volume homeostasis. , 2020, Biochemical and biophysical research communications.

[75]  I. Sagi,et al.  Emerging roles of ECM remodeling processes in cancer. , 2020, Seminars in cancer biology.

[76]  M. Franchi,et al.  Epithelial-to-Mesenchymal Transition and invadopodia markers in breast cancer: Lumican a key regulator. , 2020, Seminars in cancer biology.

[77]  E. Helal‐Neto,et al.  Extracellular Matrix Derived from High Metastatic Human Breast Cancer Triggers Epithelial-Mesenchymal Transition in Epithelial Breast Cancer Cells through αvβ3 Integrin , 2020, International journal of molecular sciences.

[78]  Sheng-Xiang Lin,et al.  Comparison of the roles of estrogens and androgens in breast cancer and prostate cancer , 2020, Journal of cellular biochemistry.

[79]  M. Coppolino,et al.  β1 integrin-mediated signaling regulates MT1-MMP phosphorylation to promote tumor cell invasion , 2020, Journal of Cell Science.

[80]  Y. Yao,et al.  Biointerface anisotropy modulates migration of breast cancer cell. , 2020, Colloids and surfaces. B, Biointerfaces.

[81]  V. Weaver,et al.  The fibrotic tumor stroma. , 2020, Biochimica et biophysica acta. Reviews on cancer.

[82]  S. Cuéllar.  Integrating trastuzumab biosimilars and HER2-directed therapies into HER2-positive breast cancer management. , 2020, The American journal of managed care.

[83]  Shelly R. Peyton,et al.  Tumor cell–organized fibronectin maintenance of a dormant breast cancer population , 2020, Science Advances.

[84]  Maoli Wang,et al.  Bioinformatics analysis of prognostic significance of COL10A1 in breast cancer , 2020, Bioscience reports.

[85]  S. Bicciato,et al.  Reprogramming normal cells into tumor precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties , 2020, Nature Materials.

[86]  Xiao-yun Song,et al.  CircACAP2 promotes breast cancer proliferation and metastasis by targeting miR-29a/b-3p-COL5A1 axis. , 2019, Life sciences.

[87]  Bayan Al-Momany,et al.  Role of CD44 in breast cancer. , 2019, Breast disease.

[88]  D. Helfman,et al.  Up-regulated fibronectin in 3D culture facilitates spreading of triple negative breast cancer cells on 2D through integrin β-5 and Src , 2019, Scientific Reports.

[89]  L. Jie,et al.  Recent treatment progress of triple negative breast cancer. , 2019, Progress in biophysics and molecular biology.

[90]  E. Andrechek,et al.  Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer. , 2019, Cell reports.

[91]  M. Smid,et al.  Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression , 2019, Breast Cancer Research.

[92]  Peter A Mollica,et al.  3D bioprinted mammary organoids and tumoroids in human mammary derived ECM hydrogels. , 2019, Acta biomaterialia.

[93]  Thomas M. Valentin,et al.  Breast Cancer Cells Transition from Mesenchymal to Amoeboid Migration in Tunable Three-Dimensional Silk-Collagen Hydrogels. , 2019, ACS biomaterials science & engineering.

[94]  D. Vynios,et al.  A guide to hyaluronan and related enzymes in breast cancer: biological significance and diagnostic value , 2019, The FEBS journal.

[95]  Ê. Ferreira,et al.  Versican and Tumor-Associated Macrophages Promotes Tumor Progression and Metastasis in Canine and Murine Models of Breast Carcinoma , 2019, Front. Oncol..

[96]  A. Suleman,et al.  Collagen Type I-Gelatin Methacryloyl Composites: Mimicking the Tumor Microenvironment. , 2019, ACS biomaterials science & engineering.

[97]  Johannes A Eble,et al.  The extracellular matrix in tumor progression and metastasis , 2019, Clinical & Experimental Metastasis.

[98]  Zhongyuan Chen,et al.  ROCK isoforms differentially modulate cancer cell motility by mechanosensing the substrate stiffness. , 2019, Acta biomaterialia.

[99]  J. D. Obayemi,et al.  A shear assay study of single normal/breast cancer cell deformation and detachment from poly-di-methyl-siloxane (PDMS) surfaces. , 2019, Journal of the mechanical behavior of biomedical materials.

[100]  M. Matsuda,et al.  An amphipathic helix of vinexin α is necessary for a substrate stiffness-dependent conformational change in vinculin , 2019, Journal of Cell Science.

[101]  Ashutosh Kumar Singh,et al.  Gelatin-Based Matrices as a Tunable Platform To Study in Vitro and in Vivo 3D Cell Invasion. , 2019, ACS applied bio materials.

[102]  Hien M. Nguyen,et al.  Specific Inhibition of Heparanase by a Glycopolymer with Well-Defined Sulfation Pattern Prevents Breast Cancer Metastasis in Mice. , 2018, ACS applied materials & interfaces.

[103]  D. Fu,et al.  Laminin is over expressed in breast cancer and facilitate cancer cell metastasis , 2018, Journal of cancer research and therapeutics.

[104]  C. Deng,et al.  Effect of Stromal Cells in Tumor Microenvironment on Metastasis Initiation , 2018, International journal of biological sciences.

[105]  G. Xiong,et al.  Membrane associated collagen XIII promotes cancer metastasis and enhances anoikis resistance , 2018, Breast Cancer Research.

[106]  Jodie M. Fleming,et al.  In Situ Drug Delivery to Breast Cancer-Associated Extracellular Matrix. , 2018, ACS chemical biology.

[107]  A. Brock,et al.  Phenotypic Basis for Matrix Stiffness-Dependent Chemoresistance of Breast Cancer Cells to Doxorubicin , 2018, Front. Oncol..

[108]  L. Martiny,et al.  Elastin molecular aging promotes MDA‐MB‐231 breast cancer cell invasiveness , 2018, FEBS open bio.

[109]  Wenjian Ma,et al.  MRTF-A mediates the activation of COL1A1 expression stimulated by multiple signaling pathways in human breast cancer cells. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[110]  Pinar Zorlutuna,et al.  Stromal cell-laden 3D hydrogel microwell arrays as tumor microenvironment model for studying stiffness dependent stromal cell-cancer interactions. , 2018, Biomaterials.

[111]  Jianhua Cao,et al.  Myricetin suppresses breast cancer metastasis through down‐regulating the activity of matrix metalloproteinase (MMP)‐2/9 , 2018, Phytotherapy research : PTR.

[112]  A. Moustakas,et al.  Serglycin promotes breast cancer cell aggressiveness: Induction of epithelial to mesenchymal transition, proteolytic activity and IL-8 signaling. , 2018, Matrix biology : journal of the International Society for Matrix Biology.

[113]  Yan Zhao,et al.  Matrix stiffness-upregulated LOXL2 promotes fibronectin production, MMP9 and CXCL12 expression and BMDCs recruitment to assist pre-metastatic niche formation , 2018, Journal of experimental & clinical cancer research : CR.

[114]  Guo‐Jun Zhang,et al.  Collagen 1A1 (COL1A1) promotes metastasis of breast cancer and is a potential therapeutic target. , 2018, Discovery medicine.

[115]  P. Mukherjee,et al.  An overview of mammographic density and its association with breast cancer , 2018, Breast Cancer.

[116]  M. Jena,et al.  Role of extracellular matrix in breast cancer development: a brief update , 2018, F1000Research.

[117]  V. Weaver,et al.  Feeling Stress: The Mechanics of Cancer Progression and Aggression , 2018, Front. Cell Dev. Biol..

[118]  F. Rubio-Moscardo,et al.  Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses , 2018, Proceedings of the National Academy of Sciences.

[119]  Rui Huang,et al.  Cell penetrating peptides functionalized gambogic acid-nanostructured lipid carrier for cancer treatment , 2018, Drug delivery.

[120]  V. Weaver,et al.  α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site , 2017, Molecular biology of the cell.

[121]  D. Radisky,et al.  Therapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer , 2017, Journal of cellular biochemistry.

[122]  Hideaki Fujita,et al.  Substrate rigidity-dependent positive feedback regulation between YAP and ROCK2 , 2017, Cell adhesion & migration.

[123]  Y. Xiong,et al.  SRGN-TGFβ2 regulatory loop confers invasion and metastasis in triple-negative breast cancer , 2017, Oncogenesis.

[124]  Huajian Gao,et al.  A non-equilibrium thermodynamic model for tumor extracellular matrix with enzymatic degradation , 2017 .

[125]  K. Wong,et al.  Targeting the Tumor Stroma: the Biology and Clinical Development of Pegylated Recombinant Human Hyaluronidase (PEGPH20) , 2017, Current Oncology Reports.

[126]  D. Ribatti,et al.  Recombinant fibromodulin and decorin effects on NF-κB and TGFβ1 in the 4T1 breast cancer cell line. , 2017, Oncology letters.

[127]  T. Putti,et al.  TRPV4 plays a role in breast cancer cell migration via Ca2+-dependent activation of AKT and downregulation of E-cadherin cell cortex protein , 2017, Oncogenesis.

[128]  K. Ueda,et al.  Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior , 2017, PloS one.

[129]  M. Franchi,et al.  Lumican effectively regulates the estrogen receptors-associated functional properties of breast cancer cells, expression of matrix effectors and epithelial-to-mesenchymal transition , 2017, Scientific Reports.

[130]  M. Götte,et al.  Syndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and EGFR signaling pathways , 2017, Molecular Cancer.

[131]  D. Amadori,et al.  Investigating the Mechanobiology of Cancer Cell–ECM Interaction Through Collagen-Based 3D Scaffolds , 2017, Cellular and Molecular Bioengineering.

[132]  G. Lianos,et al.  Breast cancer in young women: an overview , 2017, Updates in Surgery.

[133]  T. Simoncini,et al.  Thyroid Hormone Controls Breast Cancer Cell Movement via Integrin αV/β3/SRC/FAK/PI3-Kinases , 2017, Hormones and Cancer.

[134]  V. Weaver,et al.  From transformation to metastasis: deconstructing the extracellular matrix in breast cancer , 2016, Cancer and Metastasis Reviews.

[135]  Paolo A Netti,et al.  An Engineered Breast Cancer Model on a Chip to Replicate ECM‐Activation In Vitro during Tumor Progression , 2016, Advanced healthcare materials.

[136]  G. Sledge.  Curing Metastatic Breast Cancer. , 2016, Journal of oncology practice.

[137]  J. Xu,et al.  Substrate stiffness orchestrates epithelial cellular heterogeneity with controlled proliferative pattern via E-cadherin/β-catenin mechanotransduction. , 2016, Acta biomaterialia.

[138]  D. Livant,et al.  Therapeutic inhibition of breast cancer bone metastasis progression and lung colonization: breaking the vicious cycle by targeting α5β1 integrin , 2016, Breast Cancer Research and Treatment.

[139]  A. Friedl,et al.  Syndecan-1-Induced ECM Fiber Alignment Requires Integrin αvβ3 and Syndecan-1 Ectodomain and Heparan Sulfate Chains , 2016, PloS one.

[140]  T. Oskarsson,et al.  The extracellular matrix in breast cancer. , 2016, Advanced drug delivery reviews.

[141]  Joachim P. Spatz,et al.  In vitro cancer cell-ECM interactions inform in vivo cancer treatment. , 2016, Advanced drug delivery reviews.

[142]  E. Turley,et al.  Hyaluronan, Inflammation, and Breast Cancer Progression , 2015, Front. Immunol..

[143]  Baocun Sun,et al.  Transforming growth factor-β1 induces EMT by the transactivation of epidermal growth factor signaling through HA/CD44 in lung and breast cancer cells , 2015, International journal of molecular medicine.

[144]  Albert C. Chen,et al.  Matrix stiffness drives Epithelial-Mesenchymal Transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway , 2015, Nature Cell Biology.

[145]  A. Theocharis,et al.  Insights into the key roles of proteoglycans in breast cancer biology and translational medicine. , 2015, Biochimica et biophysica acta.

[146]  Z. Bhujwalla,et al.  COX-2 dependent regulation of mechanotransduction in human breast cancer cells , 2015, Cancer biology & therapy.

[147]  Kenneth M. Yamada,et al.  Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network , 2015, The Journal of cell biology.

[148]  A. Mercurio,et al.  A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells , 2015, Genes & development.

[149]  I. Kovalszky,et al.  Proteoglycans/Glycosaminoglycans: From Basic Research to Clinical Practice , 2014, BioMed research international.

[150]  O. De Wever,et al.  Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion , 2014, Oncoscience.

[151]  D E Leckband,et al.  Cadherin adhesion and mechanotransduction. , 2014, Annual review of cell and developmental biology.

[152]  David J Mooney,et al.  Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium. , 2014, Nature materials.

[153]  Michael W Davidson,et al.  Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. , 2014, Cancer research.

[154]  E. Filardo,et al.  The G Protein-Coupled Estrogen Receptor-1, GPER-1, Promotes Fibrillogenesis via a Shc-Dependent Pathway Resulting in Anchorage-Independent Growth , 2014, Hormones and Cancer.

[155]  D. Vigetti,et al.  Collagen VI and Hyaluronan: The Common Role in Breast Cancer , 2014, BioMed research international.

[156]  Shelly R. Peyton,et al.  Sorafenib resistance and JNK signaling in carcinoma during extracellular matrix stiffening. , 2014, Biomaterials.

[157]  Anindita Dutta,et al.  Extracellular Matrix Protein Laminin Induces Matrix Metalloproteinase-9 in Human Breast Cancer Cell Line MCF-7 , 2014, Cancer Microenvironment.

[158]  K. Ueda,et al.  The role of the interaction of the vinculin proline-rich linker region with vinexin &agr; in sensing the stiffness of the extracellular matrix , 2014, Journal of Cell Science.

[159]  N. Karamanos,et al.  Lumican affects tumor cell functions, tumor-ECM interactions, angiogenesis and inflammatory response. , 2014, Matrix biology : journal of the International Society for Matrix Biology.

[160]  Z. Ren,et al.  Increasing matrix stiffness upregulates vascular endothelial growth factor expression in hepatocellular carcinoma cells mediated by integrin β1. , 2014, Biochemical and biophysical research communications.

[161]  Jieqing Zhu,et al.  Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition , 2014, BMC Cancer.

[162]  P. Heldin,et al.  Deregulation of hyaluronan synthesis, degradation and binding promotes breast cancer. , 2013, Journal of biochemistry.

[163]  A. Moustakas,et al.  Serglycin Is Implicated in the Promotion of Aggressive Phenotype of Breast Cancer Cells , 2013, PloS one.

[164]  T. Oskarsson,et al.  Extracellular matrix components in breast cancer progression and metastasis. , 2013, Breast.

[165]  G. Weber.  Why does cancer therapy lack effective anti-metastasis drugs? , 2013, Cancer letters.

[166]  N. Pouliot,et al.  Laminin-511 , 2013, Cell adhesion & migration.

[167]  Stephen T. C. Wong,et al.  Microenvironmental regulation of epithelial-mesenchymal transitions in cancer. , 2012, Cancer research.

[168]  Triantafyllos Stylianopoulos,et al.  Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors , 2012, Proceedings of the National Academy of Sciences.

[169]  N. Cho,et al.  Invasive breast cancer induces laminin-332 upregulation and integrin β4 neoexpression in myofibroblasts to confer an anoikis-resistant phenotype during tissue remodeling , 2012, Breast Cancer Research.

[170]  T. Ngo,et al.  Migration of breast cancer cell lines in response to pulmonary laminin 332 , 2012, Cancer medicine.

[171]  S. Rafii,et al.  Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition. , 2012, Cancer research.

[172]  Z. Werb,et al.  The extracellular matrix: A dynamic niche in cancer progression , 2012, The Journal of cell biology.

[173]  Robin L. Anderson,et al.  Integrin‐dependent response to laminin‐511 regulates breast tumor cell invasion and metastasis , 2012, International journal of cancer.

[174]  A. Mercurio,et al.  Neuropilin-2 regulates α6β1 integrin in the formation of focal adhesions and signaling , 2012, Journal of Cell Science.

[175]  Z. Werb,et al.  Extracellular matrix degradation and remodeling in development and disease. , 2011, Cold Spring Harbor perspectives in biology.

[176]  A. Theocharis,et al.  Versican but not decorin accumulation is related to malignancy in mammographically detected high density and malignant-appearing microcalcifications in non-palpable breast carcinomas , 2011, BMC Cancer.

[177]  Wolfhard Semmler,et al.  Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE‐MRI in a longitudinal in vivo study , 2011, International journal of cancer.

[178]  David Beebe,et al.  Syndecan-1 in breast cancer stroma fibroblasts regulates extracellular matrix fiber organization and carcinoma cell motility. , 2011, The American journal of pathology.

[179]  Mina J Bissell,et al.  Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition. , 2010, Journal of cell science.

[180]  Erin Rericha,et al.  Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation , 2010, The Journal of cell biology.

[181]  Hai-wei Zhang,et al.  Endostar Suppresses Invasion Through Downregulating the Expression of Matrix Metalloproteinase-2/9 in MDA-MB-435 Human Breast Cancer Cells , 2008, Experimental biology and medicine.

[182]  L. Minafra,et al.  Breast Cancer Cells Exhibit Selective Modulation Induced by Different Collagen Substrates , 2008, Connective tissue research.

[183]  E. Nice,et al.  Evidence for a role of tumor-derived laminin-511 in the metastatic progression of breast cancer. , 2007, The American journal of pathology.

[184]  J. Peterse,et al.  Breast cancer metastasis: markers and models , 2005, Nature Reviews Cancer.

[185]  Shelly R. Peyton,et al.  Extracellular matrix rigidity governs smooth muscle cell motility in a biphasic fashion , 2005, Journal of cellular physiology.

[186]  D. Heinegård,et al.  Complexes of Matrilin-1 and Biglycan or Decorin Connect Collagen VI Microfibrils to Both Collagen II and Aggrecan* , 2003, Journal of Biological Chemistry.

[187]  Jessie L.-S. Au,et al.  Drug Delivery and Transport to Solid Tumors , 2003, Pharmaceutical Research.

[188]  Peter H Watson,et al.  Mammographic density is related to stroma and stromal proteoglycan expression , 2003, Breast Cancer Research.

[189]  D. Hocking,et al.  Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions. , 2002, Molecular biology of the cell.

[190]  T. Wight,et al.  Versican: a versatile extracellular matrix proteoglycan in cell biology. , 2002, Current opinion in cell biology.

[191]  M. Aumailley,et al.  Cell adhesion to laminin 1 or 5 induces isoform-specific clustering of integrins and other focal adhesion components. , 1998, Journal of cell science.

[192]  J. Azzopardi,et al.  Elastosis in breast cancer , 1974, Cancer.

[193]  Curt Lundmark.  Breast cancer and elastosis , 1972, Cancer.

[194]  E. Hammond,et al.  Heparanase Inhibition by Pixatimod (PG545): Basic Aspects and Future Perspectives. , 2020, Advances in experimental medicine and biology.

[195]  Yihong Wang,et al.  Elastin in the Tumor Microenvironment. , 2020, Advances in experimental medicine and biology.

[196]  A. Theocharis,et al.  The Complex Interplay Between Extracellular Matrix and Cells in Tissues. , 2019, Methods in molecular biology.

[197]  J. Itou,et al.  The Sal-like 4 - integrin α6β1 network promotes cell migration for metastasis via activation of focal adhesion dynamics in basal-like breast cancer cells. , 2017, Biochimica et biophysica acta. Molecular cell research.

[198]  Patricia J Keely,et al.  Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression. , 2011, Cold Spring Harbor perspectives in biology.

[199]  Hu Li.  Role of Vinculin in Cell Response to Mechanical Stimuli , 2009 .