Imidazole derivatives as a novel class of hybrid compounds with inhibitory histamine N-methyltransferase potencies and histamine hH3 receptor affinities.
暂无分享,去创建一个
J. Schwartz | H. Stark | Yuan H. Zhao | W. Sippl | J. Arrang | C. Ganellin | H. Pertz | X. Ligneau | W. Schunack | J. Apelt | Sven Grassmann | C. Ganellin | Jean Michel Arrang | S. Grassmann
[1] Holger Stark,et al. Development of a new class of nonimidazole histamine H(3) receptor ligands with combined inhibitory histamine N-methyltransferase activity. , 2002, Journal of medicinal chemistry.
[2] M. Nishibori,et al. Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons. , 2001, Structure.
[3] J. Schwartz,et al. Different antagonist binding properties of human and rat histamine H3 receptors. , 2001, Bioorganic & medicinal chemistry letters.
[4] H. Haas,et al. The physiology of brain histamine , 2001, Progress in Neurobiology.
[5] P. Chazot,et al. Immunological identification of the mammalian H3 histamine receptor in the mouse brain , 2001, Neuroreport.
[6] K. Tanaka,et al. Molecular cloning and characterization of a new human histamine receptor, HH4R. , 2000, Biochemical and biophysical research communications.
[7] C R Ganellin,et al. Distinct pharmacology of rat and human histamine H3 receptors: role of two amino acids in the third transmembrane domain , 2000, British journal of pharmacology.
[8] M. Erlander,et al. Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles. , 2000, The Journal of pharmacology and experimental therapeutics.
[9] J. Schwartz,et al. Cloning and cerebral expression of the guinea pig histamine H3 receptor: evidence for two isoforms , 2000, Neuroreport.
[10] M. Jackson,et al. Cloning and functional expression of the human histamine H3 receptor. , 1999, Molecular pharmacology.
[11] J. Schwartz,et al. General construction pattern of histamine H3-receptor antagonists: change of a paradigm. , 1998, Bioorganic & medicinal chemistry letters.
[12] J. Schwartz,et al. Development of FUB 181, a Selective Histamine H3‐Receptor Antagonist of High Oral in Vivo Potency with 4‐(?gv‐(Arylalkyloxy)alkyl)‐1H‐imidazole Structure , 1998, Archiv der Pharmazie.
[13] H. Stark,et al. Improvement by FUB 181, a novel histamine H3-receptor antagonist, of learning and memory in the elevated plus-maze test in mice , 1998, Naunyn-Schmiedeberg's Archives of Pharmacology.
[14] R. Leurs,et al. Therapeutic potential of histamine H3 receptor agonists and antagonists. , 1998, Trends in pharmacological sciences.
[15] H. Haas,et al. International Union of Pharmacology. XIII. Classification of histamine receptors. , 1997, Pharmacological reviews.
[16] R. Leurs,et al. Inhibition of cortical acetylcholine release and cognitive performance by histamine H3 receptor activation in rats , 1996, British journal of pharmacology.
[17] K. Matsuno,et al. Ameliorating effect of SA4503, a novel sigma 1 receptor agonist, on memory impairments induced by cholinergic dysfunction in rats. , 1996, European journal of pharmacology.
[18] J. Schwartz,et al. Inhibition of histamine versus acetylcholine metabolism as a mechanism of tacrine activity. , 1996, European journal of pharmacology.
[19] J. Schwartz,et al. Novel carbamates as potent histamine H3 receptor antagonists with high in vitro and oral in vivo activity. , 1996, Journal of medicinal chemistry.
[20] K. Onodera,et al. Effects of thioperamide, a histamine H3-receptor antagonist, on a scopolamine-induced learning deficit using an elevated plus-maze test in mice. , 1995, Life sciences.
[21] J. Schwartz,et al. [125I]iodoproxyfan, a new antagonist to label and visualize cerebral histamine H3 receptors. , 1994, The Journal of pharmacology and experimental therapeutics.
[22] J. Schwartz,et al. S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist. , 1992, The Journal of pharmacology and experimental therapeutics.
[23] S. Vincent,et al. Inhibition of histamine-N-methyltransferase (HNMT) by fragments of 9-amino-1,2,3,4-tetrahydroacridine (tacrine) and by beta-carbolines. , 1992, Biochemical pharmacology.
[24] T. Nagasu,et al. Novel sulfonamides as potential, systemically active antitumor agents. , 1992, Journal of medicinal chemistry.
[25] J. Thornton,et al. Stereochemical quality of protein structure coordinates , 1992, Proteins.
[26] Y. Itoh,et al. A Highly Sensitive Assay for Histamine Using Ion‐Pair HPLC Coupled with Postcolumn Fluorescent Derivatization: Its Application to Biological Specimens , 1992, Journal of neurochemistry.
[27] Angelo Vedani,et al. A new force field for modeling metalloproteins , 1990 .
[28] J. Schwartz,et al. Effects of histamine H3-receptor ligands on various biochemical indices of histaminergic neuron activity in rat brain. , 1989, European journal of pharmacology.
[29] J. Schwartz,et al. Autoinhibition of histamine synthesis mediated by presynaptic H3-receptors , 1987, Neuroscience.
[30] J. Schwartz,et al. Highly potent and selective ligands for histamine H3-receptors , 1987, Nature.
[31] P. Kollman,et al. An all atom force field for simulations of proteins and nucleic acids , 1986, Journal of computational chemistry.
[32] J. Schwartz,et al. Autoregulation of histamine release in brain by presynaptic H3-receptors , 1985, Neuroscience.
[33] R. Bowsher,et al. Rat histamine N-methyltransferase. Quantification, tissue distribution, purification, and immunologic properties. , 1983, The Journal of biological chemistry.
[34] J. Schwartz,et al. Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor , 1983, Nature.
[35] O. Mitsunobu. The Use of Diethyl Azodicarboxylate and Triphenylphosphine in Synthesis and Transformation of Natural Products , 1981 .
[36] G J Williams,et al. The Protein Data Bank: a computer-based archival file for macromolecular structures. , 1977, Journal of molecular biology.
[37] J. Kelley,et al. Attempted inhibition of histidine decarboxylase with beta-alkyl analogues of histidine. , 1977, Journal of medicinal chemistry.
[38] Y. Cheng,et al. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. , 1973, Biochemical pharmacology.
[39] J. Schwartz,et al. Catabolism of 3 H-histamine in the rat brain after intracisternal administration. , 1971, European journal of pharmacology.
[40] V. P. Whittaker,et al. SOME PROPERTIES OF SYNAPTIC MEMBRANES ISOLATED FROM THE CENTRAL NERVOUS SYSTEM * , 1966, Annals of the New York Academy of Sciences.
[41] A. Surrey,et al. The Role of Phenol in the Reaction of 4,7-Dichloroquinoline with Novol Diamine , 1951 .
[42] Roland L. Dunbrack,et al. Comparative modeling of CASP3 targets using PSI‐BLAST and SCWRL , 1999, Proteins.
[43] D S Goodsell,et al. Automated docking of flexible ligands: Applications of autodock , 1996, Journal of molecular recognition : JMR.
[44] J. Schwartz,et al. Histaminergic transmission in the mammalian brain. , 1991, Physiological reviews.
[45] M. Nishibori,et al. 9-Amino-1,2,3,4-tetrahydroacridine is a potent inhibitor of histamine N-methyltransferase. , 1991, Japanese journal of pharmacology.
[46] C. R. Ganellin,et al. Pharmacology of Histamine Receptors , 1982 .
[47] A. Hirshfeld,et al. The synthesis of zapotidine. , 1967, Tetrahedron.