Diabetes mellitus related bone metabolism and periodontal disease

[1]  A. Izenberg,et al.  Diabetic Neuropathies , 2015, Seminars in Neurology.

[2]  E. Bak,et al.  Diabetic characteristics and alveolar bone loss in streptozotocin- and streptozotocin-nicotinamide-treated rats with periodontitis. , 2014, Journal of periodontal research.

[3]  Liang-Jun Yan Pathogenesis of Chronic Hyperglycemia: From Reductive Stress to Oxidative Stress , 2014, Journal of diabetes research.

[4]  A. Rubio-Guerra,et al.  Diabetic nephropathy and inflammation. , 2014, World journal of diabetes.

[5]  D. Chen,et al.  Delayed Fracture Healing and Increased Callus Adiposity in a C57BL/6J Murine Model of Obesity-Associated Type 2 Diabetes Mellitus , 2014, PloS one.

[6]  G. Davey,et al.  Mesenchymal Stem Cell-Based Treatment for Microvascular and Secondary Complications of Diabetes Mellitus , 2014, Front. Endocrinol..

[7]  K. Drosatos,et al.  Palmitic Acid and DGAT1 Deficiency Enhance Osteoclastogenesis, while Oleic Acid‐Induced Triglyceride Formation Prevents It , 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[8]  I. Kanazawa,et al.  Advanced glycation end product 3 (AGE3) suppresses the mineralization of mouse stromal ST2 cells and human mesenchymal stem cells by increasing TGF-β expression and secretion. , 2014, Endocrinology.

[9]  G. Woo,et al.  Effect of the interaction between periodontitis and type 1 diabetes mellitus on alveolar bone, mandibular condyle and tibia , 2014, Acta odontologica Scandinavica.

[10]  I. Lamster Diabetes Mellitus and Oral Health: An Interprofessional Approach , 2014 .

[11]  A. Bascones-Martínez,et al.  Diabetes and periodontal disease. Review of the literature. , 2014, American journal of dentistry.

[12]  T. Hanioka,et al.  Relationship between IL1 gene polymorphisms and periodontal disease in Japanese women. , 2014, DNA and cell biology.

[13]  M. Górska,et al.  Association between type 1 diabetes and periodontal health. , 2014, Advances in medical sciences.

[14]  N. Inohara,et al.  Emerging roles of immunostimulatory oral bacteria in periodontitis development. , 2014, Trends in microbiology.

[15]  H. Newman,et al.  Obesity, diabetes mellitus, atherosclerosis and chronic periodontitis: a shared pathology via oxidative stress and mitochondrial dysfunction? , 2014, Periodontology 2000.

[16]  G. Hajishengallis Aging and its Impact on Innate Immunity and Inflammation: Implications for Periodontitis. , 2014, Journal of oral biosciences.

[17]  S. Nietzsche,et al.  Antibacterial activity of moxifloxacin on bacteria associated with periodontitis within a biofilm. , 2014, Journal of Medical Microbiology.

[18]  M. Battaglia Neutrophils and type 1 autoimmune diabetes , 2014, Current opinion in hematology.

[19]  D. Graves,et al.  Bacterial infection increases periodontal bone loss in diabetic rats through enhanced apoptosis. , 2013, The American journal of pathology.

[20]  P. Preshaw,et al.  Periodontitis: oral complication of diabetes. , 2013, Endocrinology and metabolism clinics of North America.

[21]  B G Loos,et al.  Molecular Biotypes for Periodontal Diseases? , 2013, Journal of dental research.

[22]  A. Lapolla,et al.  AGEs, rather than hyperglycemia, are responsible for microvascular complications in diabetes: a "glycoxidation-centric" point of view. , 2013, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[23]  M. Carstensen,et al.  Anti‐inflammatory cytokines and risk of type 2 diabetes , 2013, Diabetes, obesity & metabolism.

[24]  Yong-Wei Fu,et al.  Apoptosis of periodontium cells in streptozototocin- and ligature-induced experimental diabetic periodontitis in rats , 2013, Acta odontologica Scandinavica.

[25]  Shuqing Chen,et al.  IL-1Ra and its Delivery Strategies: Inserting the Association in Perspective , 2013, Pharmaceutical Research.

[26]  G. Tirabassi,et al.  Gingival advanced glycation end-products in diabetes mellitus-associated chronic periodontitis: an immunohistochemical study. , 2013, Journal of periodontal research.

[27]  D. Mooney,et al.  NF-κB inhibits osteogenic differentiation of mesenchymal stem cells by promoting β-catenin degradation , 2013, Proceedings of the National Academy of Sciences.

[28]  P. Marchetti,et al.  Reduction of Circulating Neutrophils Precedes and Accompanies Type 1 Diabetes , 2013, Diabetes.

[29]  R. Genco,et al.  Diabetes and periodontal diseases: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. , 2013, Journal of clinical periodontology.

[30]  Sneha Suresh,et al.  A comparative evaluation of antioxidant enzymes and selenium in the serum of periodontitis patients with diabetes mellitus type 2 , 2013, Contemporary clinical dentistry.

[31]  Y. Yoon,et al.  Cell Therapy for Diabetic Neuropathy Using Adult Stem or Progenitor Cells , 2013, Diabetes & metabolism journal.

[32]  Jyotika K. Fernandes,et al.  Oral Health and Type 2 Diabetes , 2013, The American journal of the medical sciences.

[33]  P. Preshaw,et al.  A review of the evidence for pathogenic mechanisms that may link periodontitis and diabetes. , 2013, Journal of clinical periodontology.

[34]  H. Kolb,et al.  Fasting and meal-stimulated residual beta cell function is positively associated with serum concentrations of proinflammatory cytokines and negatively associated with anti-inflammatory and regulatory cytokines in patients with longer term type 1 diabetes , 2013, Diabetologia.

[35]  Andre Pascal Kengne,et al.  Diabetes Mellitus and Inflammation , 2013, Current Diabetes Reports.

[36]  Thomas A Einhorn,et al.  Chemokine expression is upregulated in chondrocytes in diabetic fracture healing. , 2013, Bone.

[37]  K. Gomes,et al.  The linkage between inflammation and Type 2 diabetes mellitus. , 2013, Diabetes research and clinical practice.

[38]  G. López-Gallardo,et al.  Serum levels of bone resorption markers are decreased in patients with type 2 diabetes , 2013, Acta Diabetologica.

[39]  Katarzyna A. Broniowska,et al.  The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis , 2013, Annals of the New York Academy of Sciences.

[40]  A. Beyerlein,et al.  Reduced Blood Leukocyte and Neutrophil Numbers in the Pathogenesis of Type 1 Diabetes , 2013, Hormone and Metabolic Research.

[41]  Kenneth A. Philbrick,et al.  Peripheral leptin regulates bone formation , 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[42]  L. Terrazas,et al.  Alternatively Activated Macrophages in Types 1 and 2 Diabetes , 2012, Mediators of inflammation.

[43]  D. Graves,et al.  Gene Expression Dynamics during Diabetic Periodontitis , 2012, Journal of dental research.

[44]  P. Eke,et al.  Prevalence of Periodontitis in Adults in the United States: 2009 and 2010 , 2012, Journal of dental research.

[45]  Jens Stoye,et al.  Bacterial Community Shift in Treated Periodontitis Patients Revealed by Ion Torrent 16S rRNA Gene Amplicon Sequencing , 2012, PloS one.

[46]  T. Kavin,et al.  Diabetes and periodontal disease , 2012, Journal of pharmacy & bioallied sciences.

[47]  S. Wallet,et al.  Hyperglycemia induced and intrinsic alterations in type 2 diabetes-derived osteoclast function. , 2012, Oral diseases.

[48]  H. F. Carvalho,et al.  Sequential IL‐23 and IL‐17 and increased Mmp8 and Mmp14 expression characterize the progression of an experimental model of periodontal disease in type 1 diabetes , 2012, Journal of cellular physiology.

[49]  D. Graves,et al.  Lipid peroxidation is associated with the severity of periodontal disease and local inflammatory markers in patients with type 2 diabetes. , 2012, The Journal of clinical endocrinology and metabolism.

[50]  W. Knowler,et al.  Diabetes and oral disease: implications for health professionals , 2012, Annals of the New York Academy of Sciences.

[51]  D. Graves,et al.  Diabetes aggravates periodontitis by limiting repair through enhanced inflammation , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[52]  Y. Izumi,et al.  Improvement of glycemic control after periodontal treatment by resolving gingival inflammation in type 2 diabetic patients with periodontal disease , 2012, Journal of diabetes investigation.

[53]  Y. Li,et al.  Aggregatibacter actinomycetemcomitans Infection Enhances Apoptosis In Vivo through a Caspase-3-Dependent Mechanism in Experimental Periodontitis , 2012, Infection and Immunity.

[54]  N. Tandon,et al.  Pharmacologic Prevention of Microvascular and Macrovascular Complications in Diabetes Mellitus , 2012, American Journal of Cardiovascular Drugs.

[55]  D. Peterson,et al.  Impaired Therapeutic Capacity of Autologous Stem Cells in a Model of Type 2 Diabetes , 2012, Stem cells translational medicine.

[56]  H. F. Carvalho,et al.  Periodontal Disease-Associated Compensatory Expression of Osteoprotegerin Is Lost in Type 1 Diabetes Mellitus and Correlates with Alveolar Bone Destruction by Regulating Osteoclastogenesis , 2012, Cells Tissues Organs.

[57]  B. Dye Global periodontal disease epidemiology. , 2012, Periodontology 2000.

[58]  Bhaskar Ponugoti,et al.  Role of Forkhead Transcription Factors in Diabetes-Induced Oxidative Stress , 2012, International Journal of Experimental Diabetes Research.

[59]  M. Podar,et al.  Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing , 2011, The ISME Journal.

[60]  L. Hofbauer,et al.  Delayed bone regeneration and low bone mass in a rat model of insulin-resistant type 2 diabetes mellitus is due to impaired osteoblast function. , 2011, American journal of physiology. Endocrinology and metabolism.

[61]  G. Schett Effects of inflammatory and anti‐inflammatory cytokines on the bone , 2011, European journal of clinical investigation.

[62]  John D Lambris,et al.  Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement. , 2011, Cell host & microbe.

[63]  M. Parker,et al.  Diabetes mellitus and hip fracture: a study of 5966 cases. , 2011, Injury.

[64]  I. Reid,et al.  Skeletal phenotype of the leptin receptor–deficient db/db mouse , 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[65]  M. Prentki,et al.  Type 2 diabetes across generations: from pathophysiology to prevention and management , 2011, The Lancet.

[66]  Hyunjin Shin,et al.  State of the union between metabolism and the immune system in type 2 diabetes , 2011, Genes and Immunity.

[67]  P. Marchetti,et al.  Neutralizing Interleukin-1β (IL-1β) Induces β-Cell Survival by Maintaining PDX1 Protein Nuclear Localization* , 2011, The Journal of Biological Chemistry.

[68]  D. Graves,et al.  Inflammation and Uncoupling as Mechanisms of Periodontal Bone Loss , 2011, Journal of dental research.

[69]  D. Graves,et al.  Review of osteoimmunology and the host response in endodontic and periodontal lesions , 2011, Journal of oral microbiology.

[70]  P. O S I T I O N S T A T E M E N T,et al.  Diagnosis and Classification of Diabetes Mellitus , 2011, Diabetes Care.

[71]  T. Mattila,et al.  Influence of Intensive versus Conventional Glucose Control on Microvascular and Macrovascular Complications in Type 1 and 2 Diabetes Mellitus , 2010, Drugs.

[72]  Ferdinando Giacco,et al.  Oxidative stress and diabetic complications. , 2010, Circulation research.

[73]  Ashish R Jain,et al.  Diabetes and periodontitis , 2010, Journal of Indian Society of Periodontology.

[74]  J. Shibli,et al.  Receptor activator of nuclear factor-kappa B ligand/osteoprotegerin ratio in sites of chronic periodontitis of subjects with poorly and well-controlled type 2 diabetes. , 2010, Journal of periodontology.

[75]  T. Conrads,et al.  Identification of the Homeobox Protein Prx1 (MHox, Prrx-1) as a Regulator of Osterix Expression and Mediator of Tumor Necrosis Factor α Action in Osteoblast Differentiation , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[76]  K. Cusi The Role of Adipose Tissue and Lipotoxicity in the Pathogenesis of Type 2 Diabetes , 2010, Current diabetes reports.

[77]  Jeffrey A. Bluestone,et al.  Genetics, pathogenesis and clinical interventions in type 1 diabetes , 2010, Nature.

[78]  Thomas A Einhorn,et al.  TNF-α Mediates Diabetes-Enhanced Chondrocyte Apoptosis During Fracture Healing and Stimulates Chondrocyte Apoptosis Through FOXO1 , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[79]  A. Scutt,et al.  Diabetes Induced Changes in Rat Mesenchymal Stem Cells , 2010, Cells Tissues Organs.

[80]  Thomas A Einhorn,et al.  High levels of tumor necrosis factor-alpha contribute to accelerated loss of cartilage in diabetic fracture healing. , 2009, The American journal of pathology.

[81]  D. Hafler,et al.  Monocytes from Patients with Type 1 Diabetes Spontaneously Secrete Proinflammatory Cytokines Inducing Th17 Cells1 , 2009, The Journal of Immunology.

[82]  D. Lappin,et al.  Markers of bone destruction and formation and periodontitis in type 1 diabetes mellitus. , 2009, Journal of clinical periodontology.

[83]  E. Ding,et al.  Adiponectin levels and risk of type 2 diabetes: a systematic review and meta-analysis. , 2009, JAMA.

[84]  E. Slate,et al.  Periodontal disease status in gullah african americans with type 2 diabetes living in South Carolina. , 2009, Journal of periodontology.

[85]  Hong-bing He,et al.  [Osteoblast apoptosis in experimental diabetic periodontitis in rats]. , 2009, Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology.

[86]  E. Gómez-Barrena,et al.  Role of parathyroid hormone-related protein in the decreased osteoblast function in diabetes-related osteopenia. , 2009, Endocrinology.

[87]  R. Okazaki [Management of osteoporosis in diabetes mellitus]. , 2009, Nihon rinsho. Japanese journal of clinical medicine.

[88]  I. Silva,et al.  [Periodontal status in children and adolescents with type 1 diabetes mellitus]. , 2009, Arquivos brasileiros de endocrinologia e metabologia.

[89]  R. DeFronzo From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus , 2009, Diabetes.

[90]  T. Ohnishi,et al.  Oxidative stress causes alveolar bone loss in metabolic syndrome model mice with type 2 diabetes. , 2009, Journal of periodontal research.

[91]  D. Graves,et al.  FOXO1 Plays an Important Role in Enhanced Microvascular Cell Apoptosis and Microvascular Cell Loss in Type 1 and Type 2 Diabetic Rats , 2009, Diabetes.

[92]  D. Graves,et al.  Activation of the Acquired Immune Response Reduces Coupled Bone Formation in Response to a Periodontal Pathogen1 , 2008, The Journal of Immunology.

[93]  J. Mitsuhashi,et al.  Increased bone resorption may play a crucial role in the occurrence of osteopenia in patients with type 2 diabetes: Possible involvement of accelerated polyol pathway in its pathogenesis. , 2008, Diabetes research and clinical practice.

[94]  P. Tonin,et al.  Diabetes and osteoporosis , 2008, Aging clinical and experimental research.

[95]  R. Orbak,et al.  The Influence of Type-1 Diabetes Mellitus on Dentition and Oral Health in Children and Adolescents , 2008, Yonsei medical journal.

[96]  D. Graves,et al.  Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathy. , 2008, The American journal of pathology.

[97]  Louis F Rose,et al.  Diabetes mellitus and inflammatory periodontal diseases , 2008, Current opinion in endocrinology, diabetes, and obesity.

[98]  G. Wolf,et al.  Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy. , 2008, Current diabetes reviews.

[99]  I. Tsukamoto,et al.  Increased cathepsin K and tartrate-resistant acid phosphatase expression in bone of streptozotocin-induced diabetic rats. , 2007, Bone.

[100]  C. Andry,et al.  Resolvin E1 Regulates Inflammation at the Cellular and Tissue Level and Restores Tissue Homeostasis In Vivo1 , 2007, The Journal of Immunology.

[101]  G. Dahlquist,et al.  Worldwide childhood type 1 diabetes incidence – what can we learn from epidemiology? , 2007, Pediatric diabetes.

[102]  D. Graves,et al.  Diabetes-enhanced inflammation and apoptosis: impact on periodontal pathosis. , 2007, Periodontology 2000.

[103]  M. Casati,et al.  Overexpression of interleukin‐1β and interleukin‐6 may play an important role in periodontal breakdown in type 2 diabetic patients , 2007 .

[104]  S. Yamagishi,et al.  Molecular mechanisms of diabetic nephropathy and its therapeutic intervention. , 2007, Current drug targets.

[105]  D. Graves,et al.  Diminished Bone Formation During Diabetic Fracture Healing is Related to the Premature Resorption of Cartilage Associated With Increased Osteoclast Activity , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[106]  P. Vestergaard,et al.  Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes—a meta-analysis , 2007, Osteoporosis International.

[107]  P. Trackman,et al.  Activation of RAGE induces elevated O2− generation by mononuclear phagocytes in diabetes , 2007, Journal of leukocyte biology.

[108]  D. Graves,et al.  Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways. , 2007, Bone.

[109]  M. Moeschberger,et al.  Changes in Periodontal Health Status Are Associated with Bacterial Community Shifts as Assessed by Quantitative 16S Cloning and Sequencing , 2006, Journal of Clinical Microbiology.

[110]  Desmond E. Williams,et al.  The Burden of Diabetes Mellitus Among US Youth: Prevalence Estimates From the SEARCH for Diabetes in Youth Study , 2006, Pediatrics.

[111]  Karen C Johnson,et al.  Risk of fracture in women with type 2 diabetes: the Women's Health Initiative Observational Study. , 2006, The Journal of clinical endocrinology and metabolism.

[112]  M. Prentki,et al.  Islet beta cell failure in type 2 diabetes. , 2006, The Journal of clinical investigation.

[113]  M. Saito,et al.  Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN/Kob rats , 2006, Osteoporosis International.

[114]  D. Graves,et al.  Diabetes Enhances Periodontal Bone Loss through Enhanced Resorption and Diminished Bone Formation , 2006, Journal of dental research.

[115]  O. Johnell,et al.  Risk factors for fragility fracture in middle age. A prospective population-based study of 33,000 men and women , 2006, Osteoporosis International.

[116]  J. She,et al.  Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss. , 2006, Biochemical and biophysical research communications.

[117]  D. Graves,et al.  Diabetes enhances mRNA levels of proapoptotic genes and caspase activity, which contribute to impaired healing. , 2006, Diabetes.

[118]  T. Niwa,et al.  Advanced glycation end product modification of bone proteins and bone remodelling: hypothesis and preliminary immunohistochemical findings , 2005, Annals of the rheumatic diseases.

[119]  W. Jeffcoate,et al.  The role of proinflammatory cytokines in the cause of neuropathic osteoarthropathy (acute Charcot foot) in diabetes , 2005, The Lancet.

[120]  Panos N Papapanou,et al.  Analytical epidemiology of periodontitis. , 2005, Journal of clinical periodontology.

[121]  G. Taylor,et al.  Diabetes and Periodontal Infection: Making the Connection , 2005 .

[122]  S. Kato,et al.  Advanced Glycation End‐Products Attenuate Human Mesenchymal Stem Cells and Prevent Cognate Differentiation Into Adipose Tissue, Cartilage, and Bone , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[123]  M. Moeschberger,et al.  Identification of Candidate Periodontal Pathogens and Beneficial Species by Quantitative 16S Clonal Analysis , 2005, Journal of Clinical Microbiology.

[124]  S. Yusuf,et al.  The relationship between dysglycaemia and cardiovascular and renal risk in diabetic and non-diabetic participants in the HOPE study: a prospective epidemiological analysis , 2005, Diabetologia.

[125]  P. Vestergaard,et al.  Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk , 2005, Diabetologia.

[126]  Philip Zeitler,et al.  The global spread of type 2 diabetes mellitus in children and adolescents. , 2005, The Journal of pediatrics.

[127]  J. Rubin,et al.  The p55 TNF receptor mediates TNF inhibition of osteoblast differentiation independently of apoptosis. , 2005, American journal of physiology. Endocrinology and metabolism.

[128]  Y. Seino,et al.  Osteoclastic function is accelerated in male patients with type 2 diabetes mellitus: the preventive role of osteoclastogenesis inhibitory factor/osteoprotegerin (OCIF/OPG) on the decrease of bone mineral density. , 2005, Diabetes research and clinical practice.

[129]  J. Penninger,et al.  G(-) anaerobes-reactive CD4+ T-cells trigger RANKL-mediated enhanced alveolar bone loss in diabetic NOD mice. , 2005, Diabetes.

[130]  K. Åkesson,et al.  Increased bone density and decreased bone turnover, but no evident alteration of fracture susceptibility in elderly women with diabetes mellitus , 2005, Osteoporosis International.

[131]  E. Krall,et al.  Inflammation is More Persistent in Type 1 Diabetic Mice , 2005, Journal of dental research.

[132]  Hong-Hee Kim,et al.  Reactive oxygen species mediate RANK signaling in osteoclasts. , 2004, Experimental cell research.

[133]  S. Socransky,et al.  Subgingival microbiota of chronic periodontitis subjects from different geographic locations. , 2004, Journal of clinical periodontology.

[134]  D. Graves,et al.  Diabetes prolongs the inflammatory response to a bacterial stimulus through cytokine dysregulation. , 2004, The Journal of investigative dermatology.

[135]  C. C. Costa,et al.  [Study of the oral manifestations in diabetic children and their correlation variables]. , 2004, Arquivos brasileiros de endocrinologia e metabologia.

[136]  A. Kamer,et al.  The influence of diabetes on the periodontal tissues. , 2003, Journal of the American Dental Association.

[137]  D. Graves,et al.  A role for advanced glycation end products in diminished bone healing in type 1 diabetes. , 2003, Diabetes.

[138]  Sayon Roy,et al.  Downregulation of fibronectin overexpression reduces basement membrane thickening and vascular lesions in retinas of galactose-fed rats. , 2003, Diabetes.

[139]  M. Donath,et al.  Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function. , 2003, Diabetes.

[140]  Pamela J Schreiner,et al.  Older women with diabetes have a higher risk of falls: a prospective study. , 2002, Diabetes care.

[141]  Joseph L Evans,et al.  Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. , 2002, Endocrine reviews.

[142]  D. Graves,et al.  Inflammation and tissue loss caused by periodontal pathogens is reduced by interleukin-1 antagonists. , 2002, The Journal of infectious diseases.

[143]  G. Taylor,et al.  Glycemic control of type 2 diabetes and severe periodontal disease in the US adult population. , 2002, Community dentistry and oral epidemiology.

[144]  J. Albandar,et al.  Global epidemiology of periodontal diseases in children and young persons. , 2002, Periodontology 2000.

[145]  J. Shaw,et al.  Global and societal implications of the diabetes epidemic , 2001, Nature.

[146]  M. Brownlee Insight Review Articles , 2022 .

[147]  Graeme I. Bell,et al.  Diabetes mellitus and genetically programmed defects in β-cell function , 2001, Nature.

[148]  S. Kahn,et al.  The Importance of β-Cell Failure in the Development and Progression of Type 2 Diabetes , 2001 .

[149]  J. Klein,et al.  Metallothionein inhibits doxorubicin-induced mitochondrial cytochrome c release and caspase-3 activation in cardiomyocytes. , 2001, The Journal of pharmacology and experimental therapeutics.

[150]  J. Bergström,et al.  Smoking and subgingival microflora in periodontal disease. , 2001, Journal of clinical periodontology.

[151]  T. Tachikawa,et al.  Participation of periodontal ligament cells with regeneration of alveolar bone. , 2001, Journal of periodontology.

[152]  L. Niskanen,et al.  Salivary matrix metalloproteinase (MMP-8) levels and gelatinase (MMP-9) activities in patients with type 2 diabetes mellitus. , 2000, Journal of periodontal research.

[153]  S. Huumonen,et al.  Alveolar bone loss in type 1 diabetic subjects. , 2000, Journal of clinical periodontology.

[154]  K. Polonsky,et al.  Interactions between insulin resistance and insulin secretion in the development of glucose intolerance. , 2000, The Journal of clinical investigation.

[155]  D. Thordarson,et al.  Ankle Fusion in a High Risk Population: An Assessment of Nonunion Risk Factors , 1999, Foot & ankle international.

[156]  M. Laakso,et al.  Hyperglycemia and cardiovascular disease in type 2 diabetes. , 1999, Diabetes.

[157]  R. Natarajan,et al.  Hyperglycemia-induced activation of nuclear transcription factor kappaB in vascular smooth muscle cells. , 1999, Diabetes.

[158]  J. Baynes,et al.  Chemical modification of proteins by methylglyoxal. , 1998, Cellular and molecular biology.

[159]  M. Becker,et al.  Glycemic control and alveolar bone loss progression in type 2 diabetes. , 1998, Annals of periodontology.

[160]  A. Schmidt,et al.  Enhanced interaction of advanced glycation end products with their cellular receptor RAGE: implications for the pathogenesis of accelerated periodontal disease in diabetes. , 1998, Annals of periodontology.

[161]  Y. Seino,et al.  Circulating levels of tartrate-resistant acid phosphatase in rat models of non-insulin-dependent diabetes mellitus. , 1998, Journal of diabetes and its complications.

[162]  S. Socransky,et al.  Microbial complexes in subgingival plaque. , 1998, Journal of clinical periodontology.

[163]  D. Graves,et al.  IL-1 and TNF antagonists inhibit the inflammatory response and bone loss in experimental periodontitis. , 1998, Journal of immunology.

[164]  H. Sies,et al.  Oxidative stress: oxidants and antioxidants , 1997, Experimental physiology.

[165]  J. E. Kudlow,et al.  Glucose Metabolism to Glucosamine Is Necessary for Glucose Stimulation of Transforming Growth Factor-α Gene Transcription* , 1996, The Journal of Biological Chemistry.

[166]  K. Walker,et al.  Body fat distribution and non-insulin-dependent diabetes: comparison of a fiber-rich, high-carbohydrate, low-fat (23%) diet and a 35% fat diet high in monounsaturated fat. , 1996, The American journal of clinical nutrition.

[167]  R. Unger Lipotoxicity in the Pathogenesis of Obesity-Dependent NIDDM: Genetic and Clinical Implications , 1995, Diabetes.

[168]  D. Rao,et al.  Bone Loss and Bone Turnover in Diabetes , 1995, Diabetes.

[169]  J. Baynes,et al.  Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose. , 1995, Biochemistry.

[170]  M. Karnovsky,et al.  NADPH-oxidase expression and in situ production of superoxide by osteoclasts actively resorbing bone , 1994, The Journal of cell biology.

[171]  H. Löe Periodontal Disease: The sixth complication of diabetes mellitus , 1993, Diabetes Care.

[172]  R. Unger,et al.  Diabetic hyperglycemia: link to impaired glucose transport in pancreatic beta cells. , 1991, Science.

[173]  Paul J Thornalley The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life. , 1990, The Biochemical journal.

[174]  L. Bonewald,et al.  Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. , 1990, The Journal of clinical investigation.

[175]  Yii-Der I. Chen,et al.  Measurement of Plasma Glucose, Free Fatty Acid, Lactate, and Insulin for 24 h in Patients With NIDDM , 1988, Diabetes.

[176]  A. Cerami,et al.  Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. , 1988, The New England journal of medicine.

[177]  R. Williams,et al.  Flurbiprofen: a potent inhibitor of alveolar bone resorption in beagles. , 1985, Science.

[178]  M. Goldberg,et al.  Treatment of Diabetic Retinopathy , 1980, Diabetes.

[179]  O. Moses,et al.  Streptozotocin-induced diabetes in rats diminishes the size of the osteoprogenitor pool in bone marrow. , 2014, Diabetes research and clinical practice.

[180]  A. Al-Khabbaz Type 2 diabetes mellitus and periodontal disease severity. , 2014, Oral health & preventive dentistry.

[181]  최성호,et al.  Diabetic characteristics and alveolar bone loss in streptozotocin- and streptozotocin-nicotinamide-treated rats with periodontitis. , 2014 .

[182]  N. Sridhar,et al.  Prevalence and severity of periodontal disease in type 2 diabetes mellitus (non–insulin-dependent diabetes mellitus) patients in Bangalore city: An epidemiological study , 2013, Journal of Indian Society of Periodontology.

[183]  Dhiren P. Shah,et al.  ON OXIDATIVE STRESS AND DIABETIC COMPLICATIONS , 2013 .

[184]  E. Kohner,et al.  Introduction to diabetes mellitus. , 2012, Advances in experimental medicine and biology.

[185]  M. V. von Herrath,et al.  Type 1 diabetes: etiology, immunology, and therapeutic strategies. , 2011, Physiological reviews.

[186]  F. Zaccardi,et al.  Oxidative stress, nitric oxide, and diabetes. , 2010, The review of diabetic studies : RDS.

[187]  D. Graves,et al.  Diabetic complications and dysregulated innate immunity. , 2008, Frontiers in bioscience : a journal and virtual library.

[188]  Guangji Wang,et al.  streptozotocin- induced diabetic rats , 2008 .

[189]  T. Watts Diabetes mellitus promotes periodontal destruction in children , 2007, BDJ.

[190]  D. Daleke,et al.  The role of oxidative stress in diabetic complications , 2007, Cell Biochemistry and Biophysics.

[191]  M. Casati,et al.  Overexpression of interleukin-1beta and interleukin-6 may play an important role in periodontal breakdown in type 2 diabetic patients. , 2007, Journal of periodontal research.

[192]  Ansuman T. Satpathy,et al.  Cytokines in type 2 diabetes. , 2006, Vitamins and hormones.

[193]  Mark S. Anderson,et al.  The NOD mouse: a model of immune dysregulation. , 2005, Annual review of immunology.

[194]  L. Moyer-Mileur,et al.  Alterations in bone characteristics associated with glycemic control in adolescents with type 1 diabetes mellitus. , 2004, The Journal of pediatrics.

[195]  Louis C Gerstenfeld,et al.  Diabetes causes decreased osteoclastogenesis, reduced bone formation, and enhanced apoptosis of osteoblastic cells in bacteria stimulated bone loss. , 2004, Endocrinology.

[196]  J. Brandão-Neto,et al.  Osteopenia: a bone disorder associated with diabetes mellitus , 2004, Journal of Bone and Mineral Metabolism.

[197]  D. Graves,et al.  Diabetes interferes with the bone formation by affecting the expression of transcription factors that regulate osteoblast differentiation. , 2003, Endocrinology.

[198]  Joseph L Evans,et al.  Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction? , 2003, Diabetes.

[199]  I. Raz,et al.  Hyperglycemia and Cardiovascular Disease in Type 2 Diabetes Mellitus: Evidence-based Approach to Primary and Secondary Prevention , 2003 .

[200]  K. Maedler,et al.  Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function. , 2001, Diabetes.

[201]  G I Bell,et al.  Diabetes mellitus and genetically programmed defects in beta-cell function. , 2001, Nature.

[202]  S. Kahn Clinical review 135: The importance of beta-cell failure in the development and progression of type 2 diabetes. , 2001, The Journal of clinical endocrinology and metabolism.

[203]  W. Knowler,et al.  Non-insulin dependent diabetes mellitus and alveolar bone loss progression over 2 years. , 1998, Journal of periodontology.

[204]  A. Dedić,et al.  [Diabetes mellitus and periodontal diseases]. , 1998, Medicinski arhiv.

[205]  U. Sauer,et al.  High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells. , 1998, The Journal of clinical investigation.

[206]  T. Miyata,et al.  Possible involvement of advanced glycation end-products in bone resorption. , 1996, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[207]  B. Spiegelman,et al.  Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. , 1993, Science.

[208]  W. Ketterl [Periodontal diseases]. , 1971, Der Zahnarzt; Colloquium med. dent.

[209]  Rongkun Liu,et al.  Tumor Necrosis Factor- (cid:1) Mediates Diabetes-Enhanced Apoptosis of Matrix-Producing Cells and Impairs Diabetic Healing , 2006 .