Learning and memory in the SAMP8 mouse

[1]  J. Morley,et al.  Age-related changes in hippocampal drug facilitation of memory processing in SAMP 8 Mice , 1996, Neurobiology of Aging.

[2]  M. Alreja.  Excitatory actions of serotonin on GABAergic neurons of the medial septum and diagonal band of broca , 1996, Synapse.

[3]  J. Morley,et al.  Age-related changes in learning, memory, and lipofuscin as a function of the percentage of SAMP8 genes , 1995, Physiology & Behavior.

[4]  J. Morley,et al.  Effect of ovarian steroids on footshock avoidance learning and retention in female mice , 1995, Physiology & Behavior.

[5]  D. Harrison.  The SAM model of senescence Edited by Toshio Takeda, Elsevier Science B. V., P. O. Box 211, 1000 AE Amsterdam, The Netherlands, 1994, ISBN 0-444-81695-x, 458 pp , 1995, Experimental Gerontology.

[6]  H. Satoh,et al.  Effects of prolonged selenium deficiency on Open field behavior and Morris water maze performance in mice , 1995, Pharmacology Biochemistry and Behavior.

[7]  M. Kavaliers,et al.  Reduced spatial learning in mice infected with the nematode, Heligmosomoides polygyrus , 1995, Parasitology.

[8]  J. Morley,et al.  Age-related impairment in learning but not memory in SAMP8 female mice , 1995, Pharmacology Biochemistry and Behavior.

[9]  J. Morley,et al.  Age-related decrease of plasma testosterone in SAMP8 mice: Replacement improves age-related impairment of learning and memory , 1995, Physiology & Behavior.

[10]  L. Mucke,et al.  Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein , 1995, Nature.

[11]  R. Vertes,et al.  Extrinsic modulation of medial septal cell discharges by the ascending brainstem hippocampal synchronizing pathway , 1994, Hippocampus.

[12]  S. Ikegami.  Behavioral impairment in radial-arm maze learning and acetylcholine content of the hippocampus and cerebral cortex in aged mice , 1994, Behavioural Brain Research.

[13]  J. Morley,et al.  An amyloid β-protein fragment, Aβ[12–28], equipotently impairs post-training memory processing when injected into different limbic system structures , 1994, Brain Research.

[14]  H. L. Petri,et al.  Milacemide treatment in mice enhances acquisiton of a Morris-type water maze task , 1994, Pharmacology Biochemistry and Behavior.

[15]  S. Yamaguchi,et al.  Nicotine imptoves cognitive disturbance in senescence-accelerated mice , 1994, Pharmacology Biochemistry and Behavior.

[16]  I. Akiguchi,et al.  A novel murine model of aging, Senescence-Accelerated Mouse (SAM). , 1994, Archives of gerontology and geriatrics.

[17]  R. Vertes,et al.  The midline posterior hypothalamic region comprises a critical part of the ascending brainstem hippocampal synchronizing pathway , 1994, Hippocampus.

[18]  D. Ingram,et al.  Age-related deposition of glia-associated fibrillar material in brains of c57BL/6 mice , 1994, Neuroscience.

[19]  O. Benešová.  Neuropathobiology of Senile Dementia and Mechanism of Action of Nootropic Drugs , 1994, Drugs & aging.

[20]  J. Morley,et al.  Topography of a binding site for small amnestic peptides deduced from structure-activity studies: relation to amnestic effect of amyloid beta protein. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[21]  M. Ball,et al.  Morphological and Biochemical Analyses of Amyloid Plaque Core Proteins Purified from Alzheimer Disease Brain Tissue , 1993, Journal of neurochemistry.

[22]  J. Kimura,et al.  Beta/A4 proteinlike immunoreactive granular structures in the brain of senescence-accelerated mouse. , 1993, The American journal of pathology.

[23]  Y. Fujibayashi,et al.  Age-related changes in barrier function in mouse brain I. Accelerated age-related increase of brain transfer of serum albumin in accelerated senescence prone SAM-P/8 mice with deficits in learning and memory. , 1993, Archives of gerontology and geriatrics.

[24]  R. Schreiber,et al.  Studies on the neuronal circuits involved in the discriminative stimulus effects of 5-hydroxytryptamine1A receptor agonists in the rat. , 1993, The Journal of pharmacology and experimental therapeutics.

[25]  J. Morley,et al.  Age-related changes in footshock avoidance acquisition and retention in senescence accelerated mouse (SAM) , 1993, Neurobiology of Aging.

[26]  J. Morley,et al.  Age-related changes in the pharmacological improvement of retention in senescence accelerated mouse (SAM) , 1993, Neurobiology of Aging.

[27]  J. Reed,et al.  Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease beta A4 peptides. , 1992, Journal of molecular biology.

[28]  H. Kawamura,et al.  Age-related changes in radial-arm maze learning and basal forebrain cholinergic systems in senescence accelerated mice (SAM) , 1992, Behavioural Brain Research.

[29]  M. Mattson,et al.  β-Amyloid precursor protein and alzheimer's disease: The peptide plot thickens , 1992, Neurobiology of Aging.

[30]  C. Cotman,et al.  β-Amyloid neurotoxicity: A discussion of in vitro findings , 1992, Neurobiology of Aging.

[31]  Y. Kitamura,et al.  Age-related changes in NMDA-induced [3H]acetylcholine release from brain slices of senescene-accelerated mouse , 1992, International Journal of Developmental Neuroscience.

[32]  Y. Kitamura,et al.  Age-related changes in transmitter glutamate and NMDA receptor/channels in the brain of senescence-accelerated mouse , 1992, Neuroscience Letters.

[33]  J. Morley,et al.  Early onset of age-related impairment of aversive and appetitive learning in the SAM-P/8 mouse. , 1992, Journal of gerontology.

[34]  A. Phillips,et al.  The effects of serotonergic compounds on evoked responses in the dentate gyrus and CA1 region of the hippocampal formation of the rat , 1991, Neuropharmacology.

[35]  J. Reed,et al.  Human and rodent sequence analogs of Alzheimer's amyloid beta A4 share similar properties and can be solubilized in buffers of pH 7.4. , 1991, European journal of biochemistry.

[36]  M. Hosokawa,et al.  Senescence‐Accelerated Mouse (SAM): A Novel Murine Model of Accelerated Senescence , 1991, Journal of the American Geriatrics Society.

[37]  B. Cristie,et al.  Hippocampal theta field activity and theta-on/theta-off cell discharges are controlled by an ascending hypothalamo-septal pathway , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[38]  Y. Kitamura,et al.  Effects of bifemelane hydrochloride, a brain function improver, on muscarinic receptors in the CNS of senescence-accelerated mouse. , 1991, Japanese journal of pharmacology.

[39]  J. Morley,et al.  Amnestic effects in mice of four synthetic peptides homologous to amyloid beta protein from patients with Alzheimer disease. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[40]  Y. Kitamura,et al.  Involvement of glutamate receptor subtypes in l-[3H]noradrenaline release from cerebral cortical and hippocampal slices of mice , 1990, Neurochemistry International.

[41]  Y. Nomura,et al.  Age-related changes in uptake and release on l-[3H]noradrenaline in brain slices of senescence accelerated mouse , 1990, International Journal of Developmental Neuroscience.

[42]  A. Shimada,et al.  Age-related deterioration of long-term potentiation in the CA3 and CA1 regions of hippocampal slices from the senescence-accelerated mouse. , 1990, Archives of gerontology and geriatrics.

[43]  J. Morley,et al.  Pharmacological enhancement of long-term memory retention in old mice. , 1990, Journal of gerontology.

[44]  A. Iwai,et al.  Effects of a new TRH analogue, YM-14673, on disturbance of passive avoidance learning in senescence-accelerated mice , 1990, Pharmacology Biochemistry and Behavior.

[45]  Y. Nomura,et al.  Biochemical changes related to aging in the senescence-accelerated mouse , 1989, Experimental Gerontology.

[46]  Y. Kitamura,et al.  Ligand-binding characteristics of [3H]QNB, [3H]prazosin, [3H]rauwolscine, [3H]TCP and [3H]nitrendipine to cerebral cortical and hippocampal membranes of senescence accelerated mouse , 1989, Neuroscience Letters.

[47]  Masanori Hosokawa,et al.  Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task , 1989, Brain Research.

[48]  I. Akiguchi,et al.  Spontaneous Spongy Degeneration of the Brain Stem in SAM-P/8 Mice, a Newly Developed Memory-Deficient Strain , 1989, Journal of neuropathology and experimental neurology.

[49]  S. Kawabata,et al.  Effects of indeloxamine hydrochloride on passive avoidance behavior of senescence-accelerated mice , 1989 .

[50]  Ichiro Akiguchi,et al.  Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-P/8 as an animal model of disturbances in recent memory , 1988, Brain Research.

[51]  T. Freund,et al.  GABA-containing neurons in the septum control inhibitory interneurons in the hippocampus , 1988, Nature.

[52]  M. Hattori,et al.  Effects of repeated administration of deer antler extract on biochemical changes related to aging in senescence-accelerated mice. , 1988, Chemical & pharmaceutical bulletin.

[53]  J. Morley,et al.  Endocrinology in aging. , 1988, Disease-a-month : DM.

[54]  G. Aghajanian,et al.  Responses of hippocampal pyramidal cells to putative serotonin 5-HT1A and 5-HT1B agonists: A comparative study with dorsal raphe neurons , 1988, Neuropharmacology.

[55]  L. Amaducci,et al.  The Early Story of Alzheimer's Disease , 1987 .

[56]  J. Wehner,et al.  Effects of chronic diisopropylfluorophosphate treatment on spatial learning in mice , 1987, Pharmacology Biochemistry and Behavior.

[57]  J. Morley,et al.  Biological actions of androgens. , 1987, Endocrine reviews.

[58]  A. Nagaoka,et al.  Age-related changes in learning and memory in the senescence-accelerated mouse (SAM) , 1986, Physiology & Behavior.

[59]  C. D. Stern,et al.  Handbook of Chemical Neuroanatomy Methods in Chemical Neuroanatomy. Edited by A. Bjorklund and T. Hokfelt. Elsevier, Amsterdam, 1983. Cloth bound, 548 pp. UK £140. (Volume 1 in the series). , 1986, Neurochemistry International.

[60]  S. Yehuda,et al.  In vivo modulation of brain cholesterol level and learning performance by a novel plant lipid: indications for interactions between hippocampal-cortical cholesterol and learning. , 1986, Life sciences.

[61]  G. V. Goddard,et al.  Medial septal facilitation of hippocampal granule cell activity is mediated by inhibition of inhibitory interneurones , 1985, Brain Research.

[62]  I. Crawford,et al.  GABAergic agents on the medial septal nucleus affect hippocampal theta rhythm and acetylcholine utilization , 1984, Brain Research.

[63]  J. Flood,et al.  Memory retention: potentiation of cholinergic drug combinations in mice , 1983, Neurobiology of Aging.

[64]  H. Thompson,et al.  The transsynaptic regulation of the septal-hippocampal cholinergic neurons. , 1983, Life sciences.

[65]  D. Prince,et al.  Cholinergic excitation of mammalian hippocampal pyramidal cells , 1982, Brain Research.

[66]  Y. Ben-Ari,et al.  Intracellular observations on the disinhibitory action of acetylcholine in the hippocampus , 1981, Neuroscience.

[67]  Keiichi Higuchi,et al.  A new murine model of accelerated senescence , 1981, Mechanisms of Ageing and Development.

[68]  J. Morley,et al.  Extrahypothalamic thyrotropin releasing hormone (TRH) -- its distribution and its functions. , 1979, Life sciences.

[69]  L. Nadel,et al.  The Hippocampus as a Cognitive Map , 1978 .

[70]  M. Segal.  Responses of septal nuclei neurons to microiontophoretically administered putative neurotransmitters. , 1974, Life sciences.

[71]  E. Bennett,et al.  Comparison of the effects of anisomycin on memory across six strains of mice. , 1974, Behavioral biology.

[72]  E. Bennett,et al.  Influence of training strength on amnesia induced by pretraining injections of cycloheximide. , 1972, Physiology & behavior.

[73]  T. Takeda.  Senescence-Accelerated Mouse (SAM). A novel murine model of aging , 1994 .

[74]  N. Nishiyama,et al.  Effects of Kamikihi-To, a traditional Chinese medicine, on passive and conditioned avoidance performance impairment in senescence accelerated mouse (SAM). , 1990, Japanese journal of pharmacology.

[75]  S. Korenman,et al.  Endocrine aspects of aging. , 1980, Annals of internal medicine.