Mesenchymal stem cell homing: the devil is in the details.

[1]  John G. Laffey,et al.  Faculty Opinions recommendation of Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. , 2011 .

[2]  J. Mao,et al.  Labeling of mesenchymal stem cells with bioconjugated quantum dots. , 2011, Methods in molecular biology.

[3]  S. Eustace,et al.  Bone marrow. , 2010, Magnetic resonance imaging clinics of North America.

[4]  Jun Jiang,et al.  Anoxic preconditioning: a way to enhance the cardioprotection of mesenchymal stem cells. , 2009, International journal of cardiology.

[5]  Jeffrey M Karp,et al.  Chemical engineering of mesenchymal stem cells to induce a cell rolling response. , 2008, Bioconjugate chemistry.

[6]  K. Houkin,et al.  Optimization of a therapeutic protocol for intravenous injection of human mesenchymal stem cells after cerebral ischemia in adult rats , 2008, Brain Research.

[7]  M. Hennerici,et al.  Lipoaspirate-derived adult mesenchymal stem cells improve functional outcome during intracerebral hemorrhage by proliferation of endogenous progenitor cells Stem cells in intracerebral hemorrhages , 2008, Neuroscience Letters.

[8]  Stefanie Dimmeler,et al.  Homing and engraftment of progenitor cells: a prerequisite for cell therapy. , 2008, Journal of molecular and cellular cardiology.

[9]  S. Badylak,et al.  A perivascular origin for mesenchymal stem cells in multiple human organs. , 2008, Cell stem cell.

[10]  Jie-shou Li,et al.  Effects of transplanted bone marrow mesenchymal stem cells on the irradiated intestine of mice. , 2008, Journal of biomedical science.

[11]  N. Nardi,et al.  In Search of the In Vivo Identity of Mesenchymal Stem Cells , 2008, Stem cells.

[12]  D. Link,et al.  Hypoxic Preconditioning Results in Increased Motility and Improved Therapeutic Potential of Human Mesenchymal Stem Cells , 2008, Stem cells.

[13]  N. Perico,et al.  Human Bone Marrow Mesenchymal Stem Cells Accelerate Recovery of Acute Renal Injury and Prolong Survival in Mice , 2008, Stem cells.

[14]  S. Kostin,et al.  Efficient homing of multipotent adult mesenchymal stem cells depends on FROUNT-mediated clustering of CCR2. , 2008, Cell stem cell.

[15]  W. Bloch,et al.  Characterization of key mechanisms in transmigration and invasion of mesenchymal stem cells. , 2008, Journal of molecular and cellular cardiology.

[16]  Peter R. Brink,et al.  Culturing of Human Mesenchymal Stem Cells as Three-dimensional Aggregates Induces Functional Expression of CXCR4 That Regulates Adhesion to Endothelial Cells* , 2008, Journal of Biological Chemistry.

[17]  K. Huh,et al.  Autologous Mesenchymal Stem Cell Therapy Delays the Progression of Neurological Deficits in Patients With Multiple System Atrophy , 2008, Clinical pharmacology and therapeutics.

[18]  M. Pittenger,et al.  Dual-Modality Monitoring of Targeted Intraarterial Delivery of Mesenchymal Stem Cells After Transient Ischemia , 2008, Stroke.

[19]  P. Bianco,et al.  Mesenchymal stem cells: revisiting history, concepts, and assays. , 2008, Cell stem cell.

[20]  L. Ou,et al.  Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

[21]  S. Schiffmann,et al.  Stem cell factor and mesenchymal and neural stem cell transplantation in a rat model of Huntington's disease , 2008, Molecular and Cellular Neuroscience.

[22]  H. Shimizu,et al.  Mesenchymal Stem Cells Are Recruited into Wounded Skin and Contribute to Wound Repair by Transdifferentiation into Multiple Skin Cell Type1 , 2008, The Journal of Immunology.

[23]  M. Ashraf,et al.  Over-expression of CXCR4 on mesenchymal stem cells augments myoangiogenesis in the infarcted myocardium. , 2008, Journal of molecular and cellular cardiology.

[24]  Charles P. Lin,et al.  Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone , 2008, Nature Medicine.

[25]  W. Stanford,et al.  Late-Outgrowth Endothelial Cells Attenuate Intimal Hyperplasia Contributed by Mesenchymal Stem Cells After Vascular Injury , 2007, Arteriosclerosis, Thrombosis and Vascular Biology.

[26]  Yasuyuki Fujita,et al.  Mesenchymal Stem Cells Are Recruited into Wounded Skin and Contribute to Wound Repair by Transdifferentiation into Multiple Skin Cell Type , 2008 .

[27]  Jun Wu,et al.  Intravenously administered bone marrow cells migrate to damaged brain tissue and improve neural function in ischemic rats. , 2008, Cell transplantation.

[28]  Guosheng Lin,et al.  Insulin-like growth factor 1 improves the efficacy of mesenchymal stem cells transplantation in a rat model of myocardial infarction. , 2008, Journal of biomedical science.

[29]  Sanjay Kumar,et al.  Bone homing of mesenchymal stem cells by ectopic α4 integrin expression , 2007 .

[30]  A. Nauta,et al.  Immunomodulatory properties of mesenchymal stromal cells. , 2007, Blood.

[31]  Jihwan Song,et al.  In Vivo Tracking of Human Mesenchymal Stem Cells in Experimental Stroke , 2007, Cell transplantation.

[32]  D. Prockop,et al.  Concise Review: Mesenchymal Stem/Multipotent Stromal Cells: The State of Transdifferentiation and Modes of Tissue Repair—Current Views , 2007, Stem cells.

[33]  Jun Wu,et al.  Intravenously Administered Bone Marrow Cells Migrate to Damaged Brain Tissue and Improve Neural Function in Ischemic Rats , 2007, Cell transplantation.

[34]  A. Khademhosseini,et al.  Covalent immobilization of p-selectin enhances cell rolling. , 2007, Langmuir : the ACS journal of surfaces and colloids.

[35]  Z. Popović,et al.  SDF‐1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[36]  Dar-Ming Lai,et al.  Magnetic nanoparticle labeling of mesenchymal stem cells without transfection agent: Cellular behavior and capability of detection with clinical 1.5 T magnetic resonance at the single cell level , 2007, Magnetic resonance in medicine.

[37]  Jeremy J Mao,et al.  Labeling of mesenchymal stem cells by bioconjugated quantum dots. , 2007, Nano letters.

[38]  M. Cybulsky,et al.  Getting to the site of inflammation: the leukocyte adhesion cascade updated , 2007, Nature Reviews Immunology.

[39]  V. Dzau,et al.  Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment. , 2007, Molecular biology of the cell.

[40]  N. Gallay,et al.  The In Vitro Migration Capacity of Human Bone Marrow Mesenchymal Stem Cells: Comparison of Chemokine and Growth Factor Chemotactic Activities , 2007, Stem cells.

[41]  J. Ku,et al.  Monitoring transplanted human mesenchymal stem cells in rat and rabbit bladders using molecular magnetic resonance imaging , 2007, Neurourology and urodynamics.

[42]  R. Zhao,et al.  Regulation of CXCR4 expression in human mesenchymal stem cells by cytokine treatment: role in homing efficiency in NOD/SCID mice. , 2007, Haematologica.

[43]  P. Neth,et al.  Scientific category: Stem cells in hematology MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines , 2006 .

[44]  J. Chan,et al.  Widespread Distribution and Muscle Differentiation of Human Fetal Mesenchymal Stem Cells After Intrauterine Transplantation in Dystrophic mdx Mouse , 2007, Stem cells.

[45]  M. de Waele,et al.  Migration of culture-expanded human mesenchymal stem cells through bone marrow endothelium is regulated by matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-3. , 2007, Haematologica.

[46]  Randall J. Lee,et al.  Antibody Targeting of Stem Cells to Infarcted Myocardium , 2007, Stem cells.

[47]  C. Wan,et al.  Concise Review: Multipotent Mesenchymal Stromal Cells in Blood , 2007, Stem cells.

[48]  P. McCarthy,et al.  Monocyte Chemotactic Protein‐3 Is a Myocardial Mesenchymal Stem Cell Homing Factor , 2007, Stem cells.

[49]  Sanjay Kumar,et al.  Bone homing of mesenchymal stem cells by ectopic alpha 4 integrin expression. , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[50]  P. Hordijk Endothelial signaling in leukocyte transmigration , 2007, Cell Biochemistry and Biophysics.

[51]  E. Seifried,et al.  Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells. , 2006, Blood.

[52]  K. Houkin,et al.  Intravenous administration of glial cell line‐derived neurotrophic factor gene‐modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in the adult rat , 2006, Journal of neuroscience research.

[53]  V. Eder,et al.  Multipotential Mesenchymal Stem Cells Are Mobilized into Peripheral Blood by Hypoxia , 2006, Stem cells.

[54]  A. Bartholomew,et al.  Immunologic Consequences of Multiple, High-Dose Administration of Allogeneic Mesenchymal Stem Cells to Baboons , 2006, Cell transplantation.

[55]  Yanmin Zhang,et al.  Homing and differentiation of mesenchymal stem cells delivered intravenously to ischemic myocardium in vivo: a time-series study , 2006, Pflügers Archiv.

[56]  Yanmin Zhang,et al.  Intravenous transplantation of mesenchymal stem cells improves cardiac performance after acute myocardial ischemia in female rats , 2006, Transplant international : official journal of the European Society for Organ Transplantation.

[57]  Lindolfo da Silva Meirelles,et al.  Mesenchymal stem cells reside in virtually all post-natal organs and tissues , 2006, Journal of Cell Science.

[58]  M. Raffeld,et al.  Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma , 2006, The Journal of experimental medicine.

[59]  Robert L Wilensky,et al.  A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction. , 2006, European heart journal.

[60]  N. Gorin,et al.  Local Irradiation Not Only Induces Homing of Human Mesenchymal Stem Cells at Exposed Sites but Promotes Their Widespread Engraftment to Multiple Organs: A Study of Their Quantitative Distribution After Irradiation Damage , 2006, Stem cells.

[61]  G. D. De Keulenaer,et al.  Mesenchymal stem cell adhesion to cardiac microvascular endothelium: activators and mechanisms. , 2006, American journal of physiology. Heart and circulatory physiology.

[62]  S. Gronthos,et al.  Mesenchymal lineage precursor cells induce vascular network formation in ischemic myocardium , 2006, Nature Clinical Practice Cardiovascular Medicine.

[63]  D. Prockop,et al.  Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. , 2006, Cytotherapy.

[64]  M. Chopp,et al.  Human Marrow Stromal Cell Treatment Provides Long-lasting Benefit after Traumatic Brain Injury in Rats , 2005, Neurosurgery.

[65]  Raymond C. Boston,et al.  Dynamic Imaging of Allogeneic Mesenchymal Stem Cells Trafficking to Myocardial Infarction , 2005, Circulation.

[66]  L. Lagneaux,et al.  Mesenchymal Stem Cells Derived from CD133‐Positive Cells in Mobilized Peripheral Blood and Cord Blood: Proliferation, Oct4 Expression, and Plasticity , 2005, Stem cells.

[67]  E. Bonifacio,et al.  Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. , 2005, Blood.

[68]  J. Svennilson Novel approaches in GVHD therapy , 2005, Bone Marrow Transplantation.

[69]  U. Choi,et al.  CXCR4‐Transgene Expression Significantly Improves Marrow Engraftment of Cultured Hematopoietic Stem Cells , 2004, Stem cells.

[70]  V. Eder,et al.  Gamma irradiation induces acetylcholine-evoked, endothelium-independent relaxation and activates K-channels of isolated pulmonary artery of rats. , 2004, International journal of radiation oncology, biology, physics.

[71]  H. Okano,et al.  Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction. , 2004, Blood.

[72]  H. Ohgushi,et al.  Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis. , 2004, American journal of physiology. Heart and circulatory physiology.

[73]  L. Xia,et al.  Surface fucosylation of human cord blood cells augments binding to P-selectin and E-selectin and enhances engraftment in bone marrow. , 2004, Blood.

[74]  I. Bellantuono,et al.  A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow. , 2004, Blood.

[75]  V. Goldberg,et al.  Targeted delivery of progenitor cells for cartilage repair , 2004, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[76]  Linda G Griffith,et al.  Engineering principles of clinical cell-based tissue engineering. , 2004, The Journal of bone and joint surgery. American volume.

[77]  J. Bertho,et al.  Homing of in vitro expanded Stro-1- or Stro-1+ human mesenchymal stem cells into the NOD/SCID mouse and their role in supporting human CD34 cell engraftment. , 2004, Blood.

[78]  R. Keep,et al.  Potential role of MCP-1 in endothelial cell tight junction `opening': signaling via Rho and Rho kinase , 2003, Journal of Cell Science.

[79]  Robert A. Kloner,et al.  Systemic Delivery of Bone Marrow–Derived Mesenchymal Stem Cells to the Infarcted Myocardium: Feasibility, Cell Migration, and Body Distribution , 2003, Circulation.

[80]  Naftali Kaminski,et al.  Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[81]  B. Engelhardt,et al.  Multistep Nature of Microvascular Recruitment of Ex Vivo–expanded Embryonic Endothelial Progenitor Cells during Tumor Angiogenesis , 2003, The Journal of experimental medicine.

[82]  R. Béliveau,et al.  Hypoxia Promotes Murine Bone‐Marrow‐Derived Stromal Cell Migration and Tube Formation , 2003, Stem cells.

[83]  C. Cobbs,et al.  Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates. , 2003, Blood.

[84]  V. Starnes,et al.  Migration of mesenchymal stem cells to heart allografts during chronic rejection , 2003, Transplantation.

[85]  D. Prockop,et al.  Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[86]  W. Rombouts,et al.  Primary murine MSC show highly efficient homing to the bone marrow but lose homing ability following culture , 2003, Leukemia.

[87]  M. Shimaoka,et al.  Transition From Rolling to Firm Adhesion Is Regulated by the Conformation of the I Domain of the Integrin Lymphocyte Function-associated Antigen-1* , 2002, The Journal of Biological Chemistry.

[88]  Paul Emery,et al.  Isolation and characterization of bone marrow multipotential mesenchymal progenitor cells. , 2002, Arthritis and rheumatism.

[89]  U. V. von Andrian,et al.  Total body irradiation causes profound changes in endothelial traffic molecules for hematopoietic progenitor cell recruitment to bone marrow. , 2002, Blood.

[90]  Paul D. Kessler,et al.  Human Mesenchymal Stem Cells Differentiate to a Cardiomyocyte Phenotype in the Adult Murine Heart , 2002, Circulation.

[91]  K. Satomura,et al.  Circulating Skeletal Stem Cells , 2001, The Journal of cell biology.

[92]  A. Caplan,et al.  The Dynamic in vivo Distribution of Bone Marrow-Derived Mesenchymal Stem Cells after Infusion , 2001, Cells Tissues Organs.

[93]  Yili,et al.  Therapeutic Benefit of Intravenous Administration of Bone Marrow Stromal Cells After Cerebral Ischemia in Rats , 2001 .

[94]  M. Chopp,et al.  Therapeutic Benefit of Intravenous Administration of Bone Marrow Stromal Cells After Cerebral Ischemia in Rats , 2001, Stroke.

[95]  T. A. Hewett,et al.  Mesenchymal stem cells are capable of homing to the bone marrow of non-human primates following systemic infusion. , 2001, Experimental hematology.

[96]  O. Koç,et al.  Mesenchymal stem cells: heading into the clinic , 2001, Bone Marrow Transplantation.

[97]  S. Colla,et al.  Limited engraftment capacity of bone marrow-derived mesenchymal cells following T-cell-depleted hematopoietic stem cell transplantation , 2000 .

[98]  A. Meunier,et al.  Tissue-engineered bone regeneration , 2000, Nature Biotechnology.

[99]  A. Sigal,et al.  The LFA-1 Integrin Supports Rolling Adhesions on ICAM-1 Under Physiological Shear Flow in a Permissive Cellular Environment1 , 2000, The Journal of Immunology.

[100]  S. Colla,et al.  Limited engraftment capacity of bone marrow-derived mesenchymal cells following T-cell-depleted hematopoietic stem cell transplantation. , 2000, Blood.

[101]  R. Class,et al.  Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[102]  U. V. Andrian A massage for the journey: keeping leukocytes soft and silent. , 1997 .

[103]  U. V. von Andrian A massage for the journey: keeping leukocytes soft and silent. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[104]  T. Springer,et al.  Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18. , 1996, Blood.

[105]  T. Springer,et al.  The integrin VLA-4 supports tethering and rolling in flow on VCAM-1 , 1995, The Journal of cell biology.

[106]  M. El-Sabban,et al.  Dynamics of neutrophil rolling over stimulated endothelium in vitro. , 1994, Biophysical journal.

[107]  T. Miyazaki,et al.  Evaluation of mixed chimaerism and origin of bone marrow derived fibroblastoid cells after allogeneic bone marrow transplantation , 1994, British journal of haematology.

[108]  E. Butcher Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity , 1991, Cell.

[109]  P. Simmons,et al.  Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. , 1991, Blood.

[110]  S. Muldoon,et al.  Contractile properties of isolated vascular smooth muscle after photoradiation. , 1989, The American journal of physiology.

[111]  P. Simmons,et al.  Host origin of marrow stromal cells following allogeneic bone marrow transplantation , 1987, Nature.

[112]  G. Striker,et al.  Donor origin of the in vitro haematopoietic microenvironment after marrow transplantation in man , 1982, Nature.