References and Notes

our experimentation could eventually be used to discredit our findings, should they happen not to agree with the original observations. It seems important that all experiments in the rapidly expanding area of endocrine disruption toxicology should be carefully designed and fully reported. The use of concurrent positive and negative control groups also seems to be prudent. These needs are independent of who conducts or sponsors studies. Good science is good science. Finally, it should be noted that the only formal retraction of endocrine disruption data currently encountered derived from an academic laboratory (15), a salutary counterbalance to the assertions that stimulated this letter (1-3).

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[8]  R. Bigsby,et al.  The environmental estrogen bisphenol A stimulates prolactin release in vitro and in vivo. , 1997, Endocrinology.

[9]  K A Thayer,et al.  Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[10]  D. Roy,et al.  Profound effects of the weak environmental estrogen-like chemical bisphenol A on the growth of the mammary gland of Noble rats , 1997, The Journal of Steroid Biochemistry and Molecular Biology.

[11]  K A Thayer,et al.  Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol. , 1997, Environmental health perspectives.

[12]  W. Welshons,et al.  The Effective Free Fraction of Estradiol and Xenoestrogens in Human Serum Measured by Whole Cell Uptake Assays: Physiology of Delivery Modifies Estrogenic Activity , 1998, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[13]  R. Bigsby,et al.  The xenoestrogen bisphenol A induces growth, differentiation, and c-fos gene expression in the female reproductive tract. , 1998, Endocrinology.

[14]  R. Sharpe,et al.  Endocrine disruptors and testis development. , 1998, Environmental Health Perspectives.