Miniaturized Fourier-plane fiber scanner for OCT endoscopy

A forward-looking endoscopic optical coherence tomography (OCT) probe featuring a Fourier-plane fiber scanner is designed, manufactured and characterized. In contrast to common image-plane fiber scanners, the Fourier-plane scanner is a telecentric arrangement that eliminates vignetting and spatial resolution variations across the image plane. To scan the OCT beam in a spiral pattern, a tubular piezoelectric actuator is used to resonate an optical fiber bearing a collimating GRIN lens at its tip. The free-end of the GRIN lens sits at the back focal plane of an objective lens, such that its rotation replicates the beam angles in the collimated region of a classical telecentric 4f optical system. Such an optical arrangement inherently has a low numerical aperture combined with a relatively large field-of-view, rendering it particularly useful for endoscopic OCT imaging. Furthermore, the optical train of the Fourier-plane scanner is shorter than that of a comparable image-plane scanner by one focal length of the objective lens, significantly shortening the final arrangement. As a result, enclosed within a 3D printed housing of 2.5 mm outer diameter and 15 mm total length, the developed probe is the most compact forward-looking endoscopic OCT imager to date. Due to its compact form factor and compatibility with real-time OCT imaging, the developed probe is also ideal for use in the working channel of flexible endoscopes as a potential optical biopsy tool.

[1]  H. Zappe,et al.  Bimodal endoscopic probe combining white-light microscopy and optical coherence tomography. , 2016, Applied optics.

[2]  Audrey K. Ellerbee,et al.  Rapid scanning catheterscope for expanded forward-view volumetric imaging with optical coherence tomography. , 2015, Optics letters.

[3]  William J. Brown,et al.  Functional optical coherence tomography: principles and progress , 2015, Physics in medicine and biology.

[4]  P. Reinhall,et al.  Self-Contained Image Recalibration in a Scanning Fiber Endoscope Using Piezoelectric Sensing , 2015 .

[5]  Yixian Qian,et al.  Design of a MEMS micromirror actuated by electrostatic repulsive force , 2012 .

[6]  Sucbei Moon,et al.  Semi-resonant operation of a fiber-cantilever piezotube scanner for stable optical coherence tomography endoscope imaging , 2010, Optics express.

[7]  Xingde Li,et al.  Forward-viewing resonant fiber-optic scanning endoscope of appropriate scanning speed for 3D OCT imaging , 2010, Optics express.

[8]  Timothy D. Soper,et al.  Scanning fiber endoscopy with highly flexible, 1 mm catheterscopes for wide‐field, full‐color imaging , 2010, Journal of biophotonics.

[9]  Masayoshi Esashi,et al.  Electromagnetically driven ulutra-miniature single fiber scanner for high-resolution endoscopy fabricated on cylindrical substrates using mems process , 2010, 2010 IEEE 23rd International Conference on Micro Electro Mechanical Systems (MEMS).

[10]  Nanguang Chen,et al.  Design and development of a 3D scanning MEMS OCT probe using a novel SiOB package assembly , 2008 .

[11]  Jun Zhang,et al.  Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror , 2006 .

[12]  Richard S. Johnston,et al.  A full-color scanning fiber endoscope , 2006, SPIE BiOS.

[13]  Koji Fujimoto,et al.  Microelectromechanical flexure PZT actuated optical scanner: static and resonance behavior , 2005 .

[14]  Quinn Y. J. Smithwick,et al.  Microfabricated optical fiber with microlens that produces large field-of-view video-rate optical beam scanning for microendoscopy applications , 2003, SPIE BiOS.

[15]  Per G. Reinhall,et al.  Single-fiber flexible endoscope: general design for small size, high resolution, and wide field of view , 2001, European Conference on Biomedical Optics.

[16]  E. Valderrama,et al.  Polyimide cuff electrodes for peripheral nerve stimulation , 2000, Journal of Neuroscience Methods.

[17]  R. Muller,et al.  Magnetically actuated, addressable microstructures , 1997 .

[18]  C. J. Chen,et al.  Electromechanical deflections of piezoelectric tubes with quartered electrodes , 1992 .

[19]  Huikai Xie,et al.  Electrothermal micromirror with dual-reflective surfaces for circumferential scanning endoscopic imaging , 2009 .

[20]  G. Ripandelli,et al.  Optical coherence tomography. , 1998, Seminars in ophthalmology.