Impact of Exercise in Hypoxia on Inflammatory Cytokines in Adults: A Systematic Review and Meta-analysis

[1]  A. Russell,et al.  The acute leukocyte and cytokine response of older adults to resistance exercise in normobaric hypoxia. , 2023, Biology of sport.

[2]  Chi-Chieh Hsu,et al.  Effects of Hypoxia–Hyperoxia Preconditioning on Indicators of Muscle Damage After Acute Resistance Exercise in Male Athletes , 2022, Frontiers in Physiology.

[3]  H. Nara,et al.  Anti-Inflammatory Effect of Muscle-Derived Interleukin-6 and Its Involvement in Lipid Metabolism , 2021, International journal of molecular sciences.

[4]  S. Rosenkranz,et al.  The impact of exercise training on inflammatory markers in postmenopausal women: A systemic review and meta-analysis , 2021, Experimental Gerontology.

[5]  K. Krüger,et al.  Immunometabolic responses according to physical fitness status and lifelong exercise during aging: New roads for exercise immunology , 2021, Ageing Research Reviews.

[6]  B. Feriche,et al.  Hormonal and Inflammatory Responses to Hypertrophy-Oriented Resistance Training at Acute Moderate Altitude , 2021, International journal of environmental research and public health.

[7]  M. Symonds,et al.  The impact of high‐intensity interval training on inflammatory markers in metabolic disorders: A meta‐analysis , 2020, Scandinavian journal of medicine & science in sports.

[8]  Ben J. Lee,et al.  Prolonged treadmill running in normobaric hypoxia causes gastrointestinal barrier permeability and elevates circulating levels of pro- and anti-inflammatory cytokines. , 2020, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

[9]  D. Marinho,et al.  Inflammatory Effects of High and Moderate Intensity Exercise—A Systematic Review , 2020, Frontiers in Physiology.

[10]  L. Deldicque,et al.  Acute environmental hypoxia potentiates satellite cell‐dependent myogenesis in response to resistance exercise through the inflammation pathway in human , 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[11]  A. Żebrowska,et al.  Moderate intensity exercise in hypoxia increases IGF-1 bioavailability and serum irisin in individuals with type 1 diabetes , 2020, Therapeutic advances in endocrinology and metabolism.

[12]  J. Higgins,et al.  Cochrane Handbook for Systematic Reviews of Interventions , 2010, International Coaching Psychology Review.

[13]  C. Di Giulio,et al.  Comparison of the Effectiveness of High-Intensity Interval Training in Hypoxia and Normoxia in Healthy Male Volunteers: A Pilot Study , 2019, BioMed research international.

[14]  L. Oyama,et al.  Effect of moderate exercise under hypoxia on Th1/Th2 cytokine balance , 2019, The clinical respiratory journal.

[15]  K. Lim,et al.  Twelve weeks of exercise modality in hypoxia enhances health‐related function in obese older Korean men: A randomized controlled trial , 2019, Geriatrics & gerontology international.

[16]  R. Z. Pinto,et al.  Interleukin‐10 responses from acute exercise in healthy subjects: A systematic review , 2018, Journal of cellular physiology.

[17]  C. Minahan,et al.  The Post-Exercise Inflammatory Response to Repeated-Sprint Running in Hypoxia. , 2018, Journal of sports science & medicine.

[18]  L. Deldicque,et al.  Hypoxic Training Improves Normoxic Glucose Tolerance in Adolescents with Obesity , 2018, Medicine and science in sports and exercise.

[19]  D. Veale,et al.  Hypoxia, oxidative stress and inflammation. , 2018, Free radical biology & medicine.

[20]  B. Feriche,et al.  Oxidative stress in elite athletes training at moderate altitude and at sea level , 2018, European journal of sport science.

[21]  J. Golledge,et al.  Cytokine Responses to Acute Exercise in Healthy Older Adults: The Effect of Cardiorespiratory Fitness , 2018, Front. Physiol..

[22]  K. Goto,et al.  Postexercise serum hepcidin response to repeated sprint exercise under normoxic and hypoxic conditions. , 2018, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

[23]  M. Burtscher,et al.  High-Intensity Interval Training in Normobaric Hypoxia Leads to Greater Body Fat Loss in Overweight/Obese Women than High-Intensity Interval Training in Normoxia , 2018, Front. Physiol..

[24]  K. Goto,et al.  Post-exercise serum hepcidin levels were unaffected by hypoxic exposure during prolonged exercise sessions , 2017, PloS one.

[25]  P. Hespel,et al.  Physiological Adaptations to Hypoxic vs. Normoxic Training during Intermittent Living High , 2017, Front. Physiol..

[26]  S. Tufik,et al.  Physiological and cytokine response to acute exercise under hypoxic conditions: a pilot study. , 2017, The Journal of sports medicine and physical fitness.

[27]  K. Goto,et al.  Impact of Endurance Exercise in Hypoxia on Muscle Damage, Inflammatory and Performance Responses , 2017, Journal of strength and conditioning research.

[28]  F. Brocherie,et al.  Effects of Repeated-Sprint Training in Hypoxia on Sea-Level Performance: A Meta-Analysis , 2017, Sports Medicine.

[29]  B. Dawson,et al.  Effect of repeat-sprint training in hypoxia on post-exercise interleukin-6 and F2-isoprostanes , 2016, European journal of sport science.

[30]  S. Tufik,et al.  Carbohydrate Supplementation Influences Serum Cytokines after Exercise under Hypoxic Conditions , 2016, Nutrients.

[31]  S. Tufik,et al.  Vitamin E supplementation inhibits muscle damage and inflammation after moderate exercise in hypoxia. , 2016, Journal of human nutrition and dietetics : the official journal of the British Dietetic Association.

[32]  M. Gleeson,et al.  Effect of acute exercise and hypoxia on markers of systemic and mucosal immunity , 2016, European Journal of Applied Physiology.

[33]  William M. Brown,et al.  A Systematic Review of the Acute Effects of Exercise on Immune and Inflammatory Indices in Untrained Adults , 2015, Sports Medicine - Open.

[34]  C. Hunter,et al.  IL-6 as a keystone cytokine in health and disease , 2015, Nature Immunology.

[35]  Ben J. Lee,et al.  The impact of submaximal exercise during heat and/or hypoxia on the cardiovascular and monocyte HSP72 responses to subsequent (post 24 h) exercise in hypoxia , 2014, Extreme Physiology & Medicine.

[36]  Jiming Liu,et al.  Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range , 2014, BMC Medical Research Methodology.

[37]  D. Swinkels,et al.  Acute hypoxic exercise does not alter post-exercise iron metabolism in moderately trained endurance athletes , 2014, European Journal of Applied Physiology.

[38]  G. Semenza,et al.  Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology. , 2014, Annual review of pathology.

[39]  W. Bloch,et al.  Responses of Angiogenic Growth Factors to Exercise, to Hypoxia and to Exercise under Hypoxic Conditions , 2012, International Journal of Sports Medicine.

[40]  T. Homma,et al.  Effects of Low-Intensity Resistance Exercise Under Acute Systemic Hypoxia on Hormonal Responses , 2012, Journal of strength and conditioning research.

[41]  P. Fagenholz,et al.  Hypoxia and inflammation. , 2011, The New England journal of medicine.

[42]  J. Scheller,et al.  The pro- and anti-inflammatory properties of the cytokine interleukin-6. , 2011, Biochimica et biophysica acta.

[43]  E. Bocchi,et al.  Exercise chemosensitivity in heart failure: ventilatory, chronotropic and neurohormonal responses. , 2010, Arquivos brasileiros de cardiologia.

[44]  T. Homma,et al.  Effects of acute hypoxia on metabolic and hormonal responses to resistance exercise. , 2010, Medicine and science in sports and exercise.

[45]  B. Pedersen,et al.  ROS and myokines promote muscle adaptation to exercise , 2009, Trends in Endocrinology & Metabolism.

[46]  E. Glickman,et al.  The Immunological and Metabolic Responses to Exercise of Varying Intensities in Normoxic and Hypoxic Environments , 2008, Journal of strength and conditioning research.

[47]  A. Krook,et al.  Role of interleukin‐6 signalling in glucose and lipid metabolism , 2007, Acta physiologica.

[48]  Z. Radák,et al.  High altitude and oxidative stress , 2007, Respiratory Physiology & Neurobiology.

[49]  P. Saunders,et al.  Nonhematological mechanisms of improved sea-level performance after hypoxic exposure. , 2007, Medicine and science in sports and exercise.

[50]  J. Wang-Rodriguez,et al.  Constitutive pro- and anti-inflammatory cytokine and growth factor response to exercise in leukocytes. , 2006, Journal of applied physiology.

[51]  A. Cymerman,et al.  Cytokine responses at high altitude: effects of exercise and antioxidants at 4300 m. , 2006, Medicine and science in sports and exercise.

[52]  I. Hozo,et al.  Estimating the mean and variance from the median, range, and the size of a sample , 2005, BMC medical research methodology.

[53]  E. Swenson,et al.  Increased oxidative stress following acute and chronic high altitude exposure. , 2004, High altitude medicine & biology.

[54]  A. Steensberg,et al.  IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans. , 2003, American journal of physiology. Endocrinology and metabolism.

[55]  Bente Klarlund Pedersen,et al.  Exercise and IL‐6 infusion inhibit endotoxin‐induced TNF‐α production in humans , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[56]  B. Pedersen,et al.  The effect of graded exercise on IL‐6 release and glucose uptake in human skeletal muscle , 2003, The Journal of physiology.

[57]  A. Steensberg,et al.  Exercise and hypoxia: effects on leukocytes and interleukin-6-shared mechanisms? , 2002, Medicine and science in sports and exercise.

[58]  P. Neufer,et al.  Transcriptional activation of the IL‐6 gene in human contracting skeletal muscle: influence of muscle glycogen content , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[59]  L. Moore,et al.  Interleukin-6 response to exercise and high-altitude exposure: influence of α-adrenergic blockade , 2001 .

[60]  B. Levine,et al.  “Living high − training low” altitude training improves sea level performance in male and female élite runners , 2001, Journal of applied physiology.

[61]  I. Hendriksen,et al.  Training-induced increases in sea-level performance are enhanced by acute intermittent hypobaric hypoxia , 2001, European Journal of Applied Physiology.

[62]  David S. McClintock,et al.  Role of Oxidants in NF-κB Activation and TNF-α Gene Transcription Induced by Hypoxia and Endotoxin1 , 2000, The Journal of Immunology.

[63]  M. Tschöp,et al.  High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and C-reactive protein. , 2000, Cytokine.

[64]  S. Leeper-Woodford,et al.  Acute hypoxia increases alveolar macrophage tumor necrosis factor activity and alters NF-κB expression. , 1999, American journal of physiology. Lung cellular and molecular physiology.

[65]  G. Smith,et al.  Bias in meta-analysis detected by a simple, graphical test , 1997, BMJ.

[66]  R. O. Poyton,et al.  Oxygen sensing and molecular adaptation to hypoxia. , 1996, Physiological reviews.

[67]  B. Pedersen,et al.  Can you exercise to make your immune system fitter? , 1996, Immunology today.

[68]  M. Billah,et al.  IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells. , 1994, Journal of immunology.

[69]  C G Figdor,et al.  Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes , 1991, The Journal of experimental medicine.

[70]  D. Pyne,et al.  Immunometabolism-fit: How exercise and training can modify T cell and macrophage metabolism in health and disease. , 2022, Exercise immunology review.

[71]  H. Roschel,et al.  Inflammatory cytokine kinetics to single bouts of acute moderate and intense aerobic exercise in women with active and inactive systemic lupus erythematosus. , 2015, Exercise immunology review.

[72]  N. D. de Morton The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study. , 2009, The Australian journal of physiotherapy.

[73]  T. Serebrovskaya,et al.  Effects of intermittent hypoxia training on exercise performance, hemodynamics, and ventilation in healthy senior men. , 2008, High altitude medicine & biology.

[74]  C. Fischer Interleukin-6 in acute exercise and training: what is the biological relevance? , 2006, Exercise immunology review.

[75]  P. Bärtsch,et al.  Effect of acute mild hypoxia during exercise on plasma free and sulphoconjugated catecholamines , 2004, European Journal of Applied Physiology and Occupational Physiology.

[76]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[77]  C. Lundby,et al.  Interleukin-6 response to exercise during acute and chronic hypoxia , 2003, European Journal of Applied Physiology.