Skp2-mediated degradation of p27 regulates progression into mitosis.
暂无分享,去创建一个
Tohru Natsume | Keiichi I Nakayama | Masatoshi Kitagawa | Noriko Ishida | M. Kitagawa | Y. A. Minamishima | K. Nakayama | T. Natsume | S. Iemura | N. Ishida | S. Hatakeyama | H. Nagahama | Keiko Nakayama | Shun-ichiro Iemura | Hiroyasu Nagahama | Yohji A Minamishima | Satoshi Miyake | Shigetsugu Hatakeyama | S. Miyake | Kei-ichi Nakayama | Hiroyasu Nagahama
[1] Paul Nurse,et al. p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase , 1995, Cell.
[2] Hong Sun,et al. p27Kip1 ubiquitination and degradation is regulated by the SCFSkp2 complex through phosphorylated Thr187 in p27 , 1999, Current Biology.
[3] S. Hatakeyama,et al. Structure and expression of the gene encoding mouse F-box protein, Fwd2. , 1999, Genomics.
[4] D. Haines,et al. SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells , 2003, Oncogene.
[5] M. Scheffner,et al. Interaction between ubiquitin–protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation , 1999, Nature Cell Biology.
[6] J. Labbé,et al. Interaction between Cyclin T1 and SCFSKP2 Targets CDK9 for Ubiquitination and Degradation by the Proteasome , 2001, Molecular and Cellular Biology.
[7] T. Toda,et al. Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18. , 1997, Genes & development.
[8] K. Nakayama,et al. Phosphorylation of p27 Kip1 on Serine 10 Is Required for Its Binding to CRM1 and Nuclear Export* , 2002, The Journal of Biological Chemistry.
[9] P. Beer-Romero,et al. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. , 1995, Science.
[10] M. Kitagawa,et al. Down-regulation of p27 Kip1 by Two Mechanisms, Ubiquitin-mediated Degradation and Proteolytic Processing* , 1999, The Journal of Biological Chemistry.
[11] S. Elledge,et al. Phosphorylation-Dependent Ubiquitination of Cyclin E by the SCFFbw7 Ubiquitin Ligase , 2001, Science.
[12] K. Nakayama,et al. Degradation of p27 Kip1 at the G0-G1 Transition Mediated by a Skp2-independent Ubiquitination Pathway* , 2001, The Journal of Biological Chemistry.
[13] J. Kato,et al. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1 , 1999, Nature.
[14] Nobuyuki Shishido,et al. Mice Lacking p27 Kip1 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors , 1996, Cell.
[15] K. Nakayama,et al. Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[16] James M. Roberts,et al. A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 Kip1 -Deficient Mice , 1996, Cell.
[17] James M. Roberts,et al. Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation. , 1996, Genes & development.
[18] T. Tedder,et al. Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily. , 1989, Journal of immunology.
[19] S. Hatakeyama,et al. Spatial and temporal expression patterns of the cyclin-dependent kinase (CDK) inhibitors p27 Kip1 and p57 Kip2 during mouse development , 2001, Anatomy and Embryology.
[20] K. Manova-Todorova,et al. Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27 Kip1 , 1996, Cell.
[21] S. Reed,et al. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line , 2001, Nature.
[22] M. Kotani,et al. Stimulating effect of natural estrogens on proliferation of hepatocytes in adult mice. , 1985, Acta anatomica.
[23] K. Nakayama,et al. Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1. , 2001, Biochemical and biophysical research communications.
[24] Michele Pagano,et al. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27 , 1999, Nature Cell Biology.
[25] P. Nurse,et al. A quantitative model for the cdc2 control of S phase and mitosis in fission yeast. , 1996, Trends in genetics : TIG.
[26] K. Nakayama,et al. The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription. , 2003, Molecular cell.
[27] M. Kitagawa,et al. Ubiquitin-dependent degradation of I_B_ is mediated by a′ ubiquitin ligase Skp1/Cul 1/F-box protein FWD1. , 1999 .
[28] S. Reed,et al. Activation of cyclin E/CDK2 is coupled to site‐specific autophosphorylation and ubiquitin‐dependent degradation of cyclin E. , 1996, The EMBO journal.
[29] Y. A. Minamishima,et al. Recovery of liver mass without proliferation of hepatocytes after partial hepatectomy in Skp2-deficient mice. , 2002, Cancer research.
[30] N. Hattori,et al. Periodic expression of the cyclin-dependent kinase inhibitor p57(Kip2) in trophoblast giant cells defines a G2-like gap phase of the endocycle. , 2000, Molecular biology of the cell.
[31] Carl Co,et al. Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms , 2001, Nature.
[32] Y. Bessho,et al. Mouse Fbw7/Sel-10/Cdc4 Is Required for Notch Degradation during Vascular Development* , 2004, Journal of Biological Chemistry.
[33] J. Arbeit,et al. Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E , 1999, Nature Genetics.
[34] S. Kim,et al. Skp2 regulates Myc protein stability and activity. , 2003, Molecular cell.
[35] Wilhelm Krek,et al. p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells , 1999, Nature Cell Biology.
[36] B. Stillman,et al. Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. , 2002, Molecular cell.
[37] L. Di Marcotullio,et al. p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis , 2001, The EMBO journal.
[38] K. Klempnauer,et al. Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the Cdc34-SCFp45Skp2 pathway , 2000, Oncogene.
[39] E. Zybina,et al. Polytene chromosomes in mammalian cells. , 1996, International review of cytology.
[40] B. Clurman,et al. Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells. , 1999, Genes & development.
[41] L. Hengst,et al. CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis. , 2003, Molecular biology of the cell.
[42] M. Kitagawa,et al. Butyrolactone I, a selective inhibitor of cdk2 and cdc2 kinase. , 1993, Oncogene.
[43] Andrea C. Carrano,et al. Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation. , 1999, Genes & development.
[44] Yi-Song Wang,et al. Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E , 1999, Current Biology.
[45] L. Hengst,et al. Translational Control of p27Kip1 Accumulation During the Cell Cycle , 1996, Science.
[46] Daniel A. Haber,et al. Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines , 2001, Nature.
[47] M. Pagano,et al. Role of the SCFSkp2 Ubiquitin Ligase in the Degradation of p21Cip1 in S Phase* , 2003, Journal of Biological Chemistry.
[48] Bruno Amati,et al. Phosphorylation‐dependent degradation of the cyclin‐dependent kinase inhibitor p27Kip1 , 1997, The EMBO journal.
[49] S. Reed,et al. The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(Skp2). , 2002, Genes & development.
[50] J. Gervais,et al. Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[51] M. Kitagawa,et al. An F‐box protein, FWD1, mediates ubiquitin‐dependent proteolysis of β‐catenin , 1999, The EMBO journal.
[52] Xiaohua Wu,et al. The SCFSkp2 Ubiquitin Ligase Complex Interacts with the Human Replication Licensing Factor Cdt1 and Regulates Cdt1 Degradation* , 2003, Journal of Biological Chemistry.
[53] P. Nurse,et al. The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product , 1990, Cell.
[54] James M. Roberts,et al. Cyclin E-CDK2 is a regulator of p27Kip1. , 1997, Genes & development.
[55] M. Kitagawa,et al. Targeted disruption of Skp2 results in accumulation of cyclin E and p27Kip1, polyploidy and centrosome overduplication , 2000, The EMBO journal.