SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts
暂无分享,去创建一个
Matthew J. Silva | H. Genant | G. Krystal | J. Kalesnikoff | S. Takeshita | S. Teitelbaum | F. Ross | C. Helgason | R. Humphries | M. Brodt | Yebin Jiang | N. Namba | M. Rauh | Jenny Zhao | N. Namba
[1] M. Huber,et al. SHIP Negatively Regulates IgE + Antigen-Induced IL-6 Production in Mast Cells by Inhibiting NF-κB Activity1 , 2002, The Journal of Immunology.
[2] Y. Xu,et al. The Phox homology (PX) domain, a new player in phosphoinositide signalling. , 2001, The Biochemical journal.
[3] L. Hocking,et al. Genomewide search in familial Paget disease of bone shows evidence of genetic heterogeneity with candidate loci on chromosomes 2q36, 10p13, and 5q35. , 2001, American journal of human genetics.
[4] J. Whisstock,et al. Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: Identification of a myotubularin-related protein lacking catalytic activity , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[5] L. Cantley,et al. Translocating Tubby , 2001, Science.
[6] J. Hurley,et al. Subcellular targeting by membrane lipids. , 2001, Current opinion in cell biology.
[7] R. Parsons,et al. PTEN: life as a tumor suppressor. , 2001, Experimental cell research.
[8] S. Schurmans,et al. The lipid phosphatase SHIP2 controls insulin sensitivity , 2001, Nature.
[9] S. Takeshita,et al. TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. , 2000, The Journal of clinical investigation.
[10] S. Teitelbaum,et al. Bone resorption by osteoclasts. , 2000, Science.
[11] N. Athanasou,et al. Osteoclast differentiation from circulating mononuclear precursors in Paget's disease is hypersensitive to 1,25-dihydroxyvitamin D(3) and RANKL. , 2000, Bone.
[12] G. Krystal,et al. Lipid phosphatases in the immune system. , 2000, Seminars in immunology.
[13] S. Takeshita,et al. Identification and Characterization of the New Osteoclast Progenitor with Macrophage Phenotypes Being Able to Differentiate into Mature Osteoclasts , 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[14] D. Lucas,et al. Structure, function, and biology of SHIP proteins. , 2000, Genes & development.
[15] P. Geusens,et al. Perspectives on bone mechanical properties and adaptive response to mechanical challenge. , 1999, Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry.
[16] Matthew J. Silva,et al. Growing C57Bl/6 Mice Increase Whole Bone Mechanical Properties by Increasing Geometric and Material Properties , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[17] T. Sasaki,et al. SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival. , 1999, Genes & development.
[18] S. Morony,et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis , 1999, Nature.
[19] S. Majumdar,et al. Trabecular Bone Mineral and Calculated Structure of Human Bone Specimens Scanned by Peripheral Quantitative Computed Tomography: Relation to Biomechanical Properties , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[20] M. Huber,et al. The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[21] G. Krystal,et al. Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span. , 1998, Genes & development.
[22] D. Lacey,et al. Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation , 1998, Cell.
[23] K Yano,et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[24] R. Dubose,et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function , 1997, Nature.
[25] Brian R. Wong,et al. TRANCE Is a Novel Ligand of the Tumor Necrosis Factor Receptor Family That Activates c-Jun N-terminal Kinase in T Cells* , 1997, The Journal of Biological Chemistry.
[26] I. Babic,et al. The Src Homology 2 (SH2) Domain of SH2-containing Inositol Phosphatase (SHIP) Is Essential for Tyrosine Phosphorylation of SHIP, Its Association with Shc, and Its Induction of Apoptosis* , 1997, The Journal of Biological Chemistry.
[27] S. Mckercher,et al. Osteopetrosis in mice lacking haematopoietic transcription factor PU.1 , 1997, Nature.
[28] G. Krystal,et al. Cloning and characterization of human SHIP, the 145-kD inositol 5-phosphatase that associates with SHC after cytokine stimulation. , 1996, Blood.
[29] G. Roodman. Paget's disease and osteoclast biology. , 1996, Bone.
[30] P. Majerus,et al. The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[31] A. DeFranco,et al. Activation-induced Association of a 145-kDa Tyrosine-phosphorylated Protein with Shc and Syk in B Lymphocytes and Macrophages (*) , 1996, The Journal of Biological Chemistry.
[32] Sakae Tanaka,et al. Wortmannin, a specific inhibitor of phosphatidylinositol‐3 kinase, blocks osteoclastic bone resorption , 1995, FEBS letters.
[33] L. Williams,et al. An alternative to SH2 domains for binding tyrosine-phosphorylated proteins. , 1994, Science.
[34] G. Krystal,et al. Multiple cytokines stimulate the binding of a common 145-kilodalton protein to Shc at the Grb2 recognition site of Shc , 1994, Molecular and cellular biology.
[35] R. Aebersold,et al. B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein. , 1994, Journal of immunology.
[36] R. Salgia,et al. Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and steel factor and is constitutively increased by p210BCR/ABL. , 1994, The Journal of biological chemistry.
[37] M. Drezner,et al. Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee , 1987 .
[38] K. Kumar. Paget's disease of bone. , 1986, Calcified tissue international.
[39] L. McManus,et al. Identification and characterization of osteoclast-like cells and their progenitors in cultures of feline marrow mononuclear cells , 1984, The Journal of cell biology.
[40] A. Vignery,et al. Dynamic histomorphometry of alveolar bone remodeling in the adult rat , 1980, The Anatomical record.
[41] D H COLLINS,et al. PAGET'S DISEASE OF BONE: INCIDENCE AND SUBCLINICAL FORMS , 1956 .
[42] M. Horowitz,et al. Local Regulators of Bone: IL-1, TNF, Lymphotoxin, Interferon-γ, IL-8, IL-10, IL-4, the LIF/IL-6 Family, and Additional Cytokines , 2002 .
[43] R. Wallace,et al. Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis , 2000, Nature Genetics.
[44] A. M. Parfitt,et al. Bone Histomorphometry: System for Standardization of Nomenclature, Symbols, and Units , 1988 .
[45] S. Niida,et al. BriefDefinitive Report Essential Role of Macrophage Colony-Stimulating Factor in the Osteoclast Differentiation Supported by , 2022 .