Exercise training during anthracycline-based chemotherapy for breast cancer.

e12110Background: Breast Cancer is the most common female malignancy in Australia and worldwide. Medical advancements in breast cancer detection, diagnosis, and treatment have increased the 5 year-survival rate to 90%, so a focus on non-breast cancer related causes of morbidity and mortality have emerged. Anthracycline-chemotherapy has had considerable success in reducing tumour size, cancer recurrence and improving survival rates but significant adverse effects including reductions in VO2peak and cardiac function. Exercise training may provide a treatment option to reduce the cardiotoxic and fitness declines seen in women treated with anthracycline-based chemotherapy. Therefore this study aims to investigate the effects of exercise training for women recently diagnosed with breast cancer undergoing anthracycline chemotherapy Methods: 20 women recently diagnosed with breast cancer were evenly split into either usual care (UC, n = 10, age 49.2 ± 13.4yrs, Ht 164 ± 0.09cm, Wt 77.4 ± 19.7kg, BMI 23.5 ± 5.4) o...