Cardiovascular and pulmonary dynamics by quantitative imaging.

The accuracy and range of studies on cardiovascular and pulmonary functions can be greatly facilitated if the motions of the underlying organ systems throughout individual cycles can be directly visualized and readily measured with minimum or preferably no effect on these motions. Achievement of this objective requires development of techniques for quantitative noninvasive or minimally invasive dynamic and stop-action imaging of the organ systems. A review of advances in dynamic quantitative imaging of moving organs reveals that the revolutionary value of cross-sectional and three-dimensional images produced by various types of radiant energy such as X-rays and gamma rays, positrons, electrons, protons, light, and ultrasound for clinical diagnostic and biomedical research applications is just beginning to be realized. The fabrication of a clinically useful cross-section reconstruction device with sensing capabilities for both anatomical structural composition and chemical composition may be possible and awaits future development.

[1]  Richard A. Robb,et al.  THREE-DIMENSIONAL RECONSTRUCTION AND DISPLAY OF THE WORKING CANINE HEART AND LUNGS BY MULTIPLANAR X-RAY SCANNING VIDEODENSITOMETRY. , 1800 .

[2]  R. Bracewell.  Strip Integration in Radio Astronomy , 1956 .

[3]  E H WOOD,et al.  Speculations Concerning Present and Future Developments In Indicator‐Dilution Technics , 1962, Circulation research.

[4]  E H WOOD,et al.  Diagnostic Applications of Indicator‐Dilution Technics In Congenital Heart Disease , 1962, Circulation research.

[5]  A. Cormack.  Representation of a Function by Its Line Integrals, with Some Radiological Applications , 1963 .

[6]  D. J. De Rosier,et al.  Reconstruction of Three Dimensional Structures from Electron Micrographs , 1968, Nature.

[7]  J L Gimenez,et al.  Selection of optimum cineradiographic frame rate: relation to accuracy of cardiac measurements. , 1970, Investigative radiology.

[8]  M. Goitein.  Three-dimensional density reconstruction from a series of two-dimensional projections , 1972 .

[9]  R. Michael Perry,et al.  On determining the electron density distribution of the solar corona from K-coronameter data , 1972 .

[10]  P. Gilbert.  Iterative methods for the three-dimensional reconstruction of an object from projections. , 1972, Journal of theoretical biology.

[11]  G T Herman,et al.  ART: mathematics and applications. A report on the mathematical foundations and on the applicability to real data of the algebraic reconstruction techniques. , 1973, Journal of theoretical biology.

[12]  Thomas F. Budinger,et al.  Quantitative sequential imaging of radionuclide distribution using the whole-body scanner and the gamma camera: absolute accuracy and aspects of three-dimensional reconstruction , 1973 .

[13]  E H Wood,et al.  Biplane roentgen videometric system for dynamic (60-sec) studies of the shape and size of circulatory structures, particularly the left ventricle. , 1973, The American journal of cardiology.

[14]  E H Wood,et al.  Recording of multichannel analog data and video images on the same video tape or disc. , 1974, Journal of applied physiology.

[15]  William E. Engeler,et al.  Intracell charge-transfer structures for signal processing , 1974 .

[16]  R S Ledley,et al.  The ACTA-scanner: the whole body computerized transaxial tomograph. , 1974, Computers in biology and medicine.

[17]  E H Wood,et al.  Finite-element analysis of left ventricular myocardial stresses. , 1974, Journal of biomechanics.

[18]  J. Taveras,et al.  Computerized axial tomography with the EMI scanner. , 1974, Radiology.

[19]  R. Ledley,et al.  Computerized Transaxial X-ray Tomography of the Human Body , 1974, Science.

[20]  S. L. Lee,et al.  The problem of accurate measurement of left ventricular shape and dimensions from multiplane roentgenographic data. , 1974, European journal of cardiology.

[21]  James F. Greenleaf,et al.  An Operator-Interactive, Computer-Controlled System For High Fidelity Digitization And Analysis Of Biomedical Images , 1974, Optics & Photonics.

[22]  R H Tutton,et al.  Computerized axial tomography (EMI scanner). , 1974, The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society.

[23]  E C McCullough,et al.  An evaluation of the quantitative and radiation features of a scanning x-ray transverse axial tomograph: the EMI scanner. , 1974, Radiology.

[24]  G T Herman,et al.  Dynamic three-dimensional reconstruction of beating heart and lungs from multiplanar roentgen-television images. , 1974, Mayo Clinic proceedings.

[25]  G T Herman,et al.  Three-dimensional visualization of the intact thorax and contents: a technique for cross-sectional reconstruction from multiplanar x-ray views. , 1974, Computers and biomedical research, an international journal.

[26]  C B Holman,et al.  Computer assisted tomography of the head. An early evaluation. , 1974, Mayo Clinic proceedings.

[27]  S. A. Johnson,et al.  Digital Computer Simulation Study of a Real-Time Collection, Post-Processing Synthetic Focusing Ultrasound Cardiac Camera , 1975 .

[28]  Gabor T. Herman,et al.  Three-Dimensional Reconstruction from Projections: A Review of Algorithms , 1975, Other Conferences.

[29]  J. Greenleaf,et al.  ALGEBRAIC RECONSTRUCTION OF SPATIAL DISTRIBUTIONS OF ACOUSTIC VELOCITIES IN TISSUE FROM THEIR TIME-OF-FLIGHT PROFILES. , 1975 .

[30]  T. F. Budinger.  Three-Dimensional Imaging Of The Myocardium With Isotopes , 1976, Other Conferences.

[31]  R. E. Sturm,et al.  Quantitative Three-Dimensional Dynamic Imaging Of Structure And Function Of The Cardiopulmonary And Circulatory Systems In All Regions Of The Body , 1976, Other Conferences.

[32]  E H Wood,et al.  New horizons for study of the cardiopulmonary and circulatory systems. , 1976, Chest.

[33]  Michael E. Phelps,et al.  Positron Emission Reconstruction Tomography For The Assessment Of Regional Myocardial Metabolism By The Administration Of Substrates Labeled With Cyclotron Produced Radionuclides , 1976, Other Conferences.