The Variability of Growth and Puberty in Growth Hormone-treated Children Born Small for Gestational Age

Growth is a complex process in which numerous factors each have different impacts on adult height. A person’s genetics is one of the major determinants of adult height, hence the utility of calculating the mid-parental height (MPH) when making an adult height prediction during the evaluation of short stature. Other factors include nutrition, especially in the infant years; the pulsatile action of the GH-insulin growth-like driving height in childhood; puberty, both the rate the timing of of a cardinal on height, the puberty begins, the duration of puberty, the rate of growth during puberty strongly influence adult height growth puberty