Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells
暂无分享,去创建一个
S. Karim | J. Morton | A. E. del Río Hernández | D. Lachowski | E. Cortes | A. Rice | Saadia A. Karim | A J Rice | E Cortes | D Lachowski | B C H Cheung | S A Karim | J P Morton | A del Río Hernández | B. Cheung | Dariusz Lachowski | Alistair Rice | A. D. R. Hernandez
[1] F. Ciardiello,et al. NAB-paclitaxel and gemcitabine in metastatic pancreatic ductal adenocarcinoma (PDAC): from clinical trials to clinical practice , 2016, BMC Cancer.
[2] Huamin Wang,et al. Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. , 2009, Cancer research.
[3] Xiaocan Guo,et al. Integration of mechanical and chemical signals by YAP and TAZ transcription coactivators , 2013, Cell & Bioscience.
[4] Prasenjit Dey,et al. Genetics and biology of pancreatic ductal adenocarcinoma , 2006, Genes & development.
[5] Simon C. Potter,et al. A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans , 2012, PLoS ONE.
[6] V. Weaver,et al. The extracellular matrix modulates the hallmarks of cancer , 2014, EMBO reports.
[7] A. Maitra,et al. Genetics and pathology of pancreatic cancer. , 2006, HPB : the official journal of the International Hepato Pancreato Biliary Association.
[8] G. Charras,et al. Experimental validation of atomic force microscopy-based cell elasticity measurements , 2011, Nanotechnology.
[9] R. DePinho,et al. Genetics and biology of pancreatic ductal adenocarcinoma. , 2006, Genes & development.
[10] P. Janmey,et al. Substrate stiffness regulates solubility of cellular vimentin , 2014, Molecular biology of the cell.
[11] Ueli Aebi,et al. The nanomechanical signature of breast cancer. , 2012, Nature nanotechnology.
[12] Alfonso Bellacosa,et al. Epithelial–mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways , 2005, Oncogene.
[13] Sirio Dupont. Role of YAP/TAZ in mechanotransduction , 2011 .
[14] P. Whittaker,et al. Collagen and picrosirius red staining: a polarized light assessment of fibrillar hue and spatial distribution , 2005 .
[15] R. Hruban,et al. Pancreatic cancer , 2011, The Lancet.
[16] Kun-Liang Guan,et al. The emerging roles of YAP and TAZ in cancer , 2015, Nature Reviews Cancer.
[17] H. Richardson,et al. Tissue growth and tumorigenesis in Drosophila: cell polarity and the Hippo pathway. , 2017, Current opinion in cell biology.
[18] E. Neilson,et al. Biomarkers for epithelial-mesenchymal transitions. , 2009, The Journal of clinical investigation.
[19] Sandra J Shefelbine,et al. BoneJ: Free and extensible bone image analysis in ImageJ. , 2010, Bone.
[20] Xiang-Dong Fu,et al. Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling , 2012, Cell.
[21] Caroline H. Diep,et al. Down-Regulation of Yes Associated Protein 1 Expression Reduces Cell Proliferation and Clonogenicity of Pancreatic Cancer Cells , 2012, PloS one.
[22] Caroline H. Diep,et al. Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer , 2015, Clinical Cancer Research.
[23] M. Hollingsworth,et al. P-selectin expression in a metastatic pancreatic tumor cell line (SUIT-2). , 1997, Cancer research.
[24] C. Chen,et al. Acquisition of epithelial–mesenchymal transition is associated with Skp2 expression in paclitaxel-resistant breast cancer cells , 2014, British Journal of Cancer.
[25] B. Melichar,et al. Therapeutic potential of taxanes in the treatment of metastatic pancreatic cancer , 2016, Cancer Chemotherapy and Pharmacology.
[26] Jingwu Xie,et al. Promising molecular mechanisms responsible for gemcitabine resistance in cancer , 2015, Genes & diseases.
[27] S. Bicciato,et al. The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells , 2011, Cell.
[28] L. Bujanda,et al. Mouse models of pancreatic cancer. , 2012, World journal of gastroenterology.
[29] Anna B. Osipovich,et al. Pancreas-specific Cre driver lines and considerations for their prudent use. , 2013, Cell metabolism.
[30] J. Iredale,et al. Type I Collagen Promotes the Malignant Phenotype of Pancreatic Ductal Adenocarcinoma , 2004, Clinical Cancer Research.
[31] M. Jordan,et al. Microtubules as a target for anticancer drugs , 2004, Nature Reviews Cancer.
[32] M. Greene,et al. Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis , 2015, Scientific Reports.
[33] K. Guan,et al. The Hippo-YAP pathway: new connections between regulation of organ size and cancer. , 2008, Current opinion in cell biology.
[34] M. Karin,et al. A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis , 2015, Genes & development.
[35] Jason D. Fowler,et al. Kinetic Investigation of the Inhibitory Effect of Gemcitabine on DNA Polymerization Catalyzed by Human Mitochondrial DNA Polymerase* , 2008, Journal of Biological Chemistry.
[36] M. Hidalgo,et al. The Winning Formulation: The Development of Paclitaxel in Pancreatic Cancer , 2013, Clinical Cancer Research.
[37] M. Biffoni,et al. TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells , 2014, Oncogene.
[38] Y Quijano,et al. Stromal disrupting effects of nab-paclitaxel in pancreatic cancer , 2013, British Journal of Cancer.
[39] E. Karamitopoulou. Role of Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Is Tumor Budding the Missing Link? , 2013, Front. Oncol..
[40] D. Tuveson,et al. nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer. , 2012, Cancer discovery.
[41] V. LeBleu,et al. EMT Program is Dispensable for Metastasis but Induces Chemoresistance in Pancreatic Cancer , 2015, Nature.
[42] Cynthia A. Reinhart-King,et al. Tensional homeostasis and the malignant phenotype. , 2005, Cancer cell.
[43] Albert C. Chen,et al. Matrix stiffness drives Epithelial-Mesenchymal Transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway , 2015, Nature Cell Biology.
[44] B. R. Bass,et al. 3D collagen alignment limits protrusions to enhance breast cancer cell persistence. , 2014, Biophysical journal.
[45] Richard G. Posner,et al. Desmoplasia and chemoresistance in pancreatic cancer , 2012 .
[46] J. Vandekerckhove,et al. The phalloidin binding site of F‐actin. , 1985, The EMBO journal.
[47] Agnes G Loeffler,et al. Periductal stromal collagen topology of pancreatic ductal adenocarcinoma differs from that of normal and chronic pancreatitis , 2015, Modern Pathology.
[48] A. Schetter,et al. Inducible nitric oxide synthase enhances disease aggressiveness in pancreatic cancer , 2016, Oncotarget.
[49] E. Mini,et al. Cellular pharmacology of gemcitabine. , 2006, Annals of oncology : official journal of the European Society for Medical Oncology.
[50] C. Farah,et al. Epithelial to mesenchymal transition (EMT) biomarkers--E-cadherin, beta-catenin, APC and Vimentin--in oral squamous cell carcinogenesis and transformation. , 2012, Oral oncology.
[51] Mikala Egeblad,et al. Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling , 2009, Cell.
[52] Manuel Hidalgo,et al. Addressing the challenges of pancreatic cancer: future directions for improving outcomes. , 2015, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
[53] A. E. del Río Hernández,et al. Quantitative analysis of 3D extracellular matrix remodelling by pancreatic stellate cells , 2016, Biology Open.
[54] G. Halder,et al. The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment , 2013, Nature Reviews Drug Discovery.
[55] Elvi Hayani,et al. HUBUNGAN ANTARA KASUS MALARIA DENGAN KONDISI SANITASI RUMAH TEMPAT TINGGAL DI PUSKESMAS PASAR MANNA KABUPATEN BENGKULU SELATAN , 2018, Naturalis: Jurnal Penelitian Pengelolaan Sumber Daya Alam dan Lingkungan.
[56] Xiao-Jun Ma,et al. Role of three‐dimensional matrix stiffness in regulating the chemoresistance of hepatocellular carcinoma cells , 2015, Biotechnology and applied biochemistry.
[57] Aude Michel,et al. Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure , 2015, Nature.
[58] M. Imamura,et al. Analysis of E-, N-Cadherin, α-, β-, and γ-Catenin Expression in Human Pancreatic Carcinoma Cell Lines , 2005, Pancreas.
[59] J. Shea,et al. Phenotype and Genotype of Pancreatic Cancer Cell Lines , 2010, Pancreas.
[60] Christine A Iacobuzio-Donahue,et al. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular-fibrosis and tumor progression , 2016, Nature Medicine.
[61] M. Barbacid,et al. Genetically engineered mouse models of pancreatic adenocarcinoma , 2013, Molecular oncology.
[62] Alexander A. Fingerle,et al. The role of stroma in pancreatic cancer: diagnostic and therapeutic implications , 2012, Nature Reviews Gastroenterology &Hepatology.
[63] Samy Lamouille,et al. Molecular mechanisms of epithelial–mesenchymal transition , 2014, Nature Reviews Molecular Cell Biology.