cAMP signaling in Dictyostelium

[1]  M. Meima,et al.  Characterization of a cAMP-stimulated cAMP Phosphodiesterase inDictyostelium discoideum * , 2003, The Journal of Biological Chemistry.

[2]  R. Biondi,et al.  Identification of a novel type of cGMP phosphodiesterase that is defective in the chemotactic stmF mutants. , 2002, Molecular biology of the cell.

[3]  P. V. van Haastert,et al.  Identification and characterization of two unusual cGMP-stimulated phoshodiesterases in dictyostelium. , 2002, Molecular biology of the cell.

[4]  D. Dormann,et al.  Visualizing PI3 Kinase-Mediated Cell-Cell Signaling during Dictyostelium Development , 2002, Current Biology.

[5]  A. Kimmel,et al.  Gα-Mediated Inhibition of Developmental Signal Response , 2002, Current Biology.

[6]  A. Kuspa,et al.  Role for YakA, cAMP, and protein kinase A in regulation of stress responses of Dictyostelium discoideum cells. , 2002, Molecular biology of the cell.

[7]  P. V. van Haastert,et al.  Identification of four candidate cGMP targets in Dictyostelium , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[8]  Hideko Urushihara,et al.  A transcriptional profile of multicellular development in Dictyostelium discoideum. , 2002, Development.

[9]  S. Jin,et al.  Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling , 2002, Trends in Endocrinology & Metabolism.

[10]  K. Shiozaki,et al.  Fungal Histidine Kinases , 2001, Science's STKE.

[11]  G. Spiegelman,et al.  RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation , 2001, The EMBO journal.

[12]  R. Firtel,et al.  Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium. , 2001, Genes & development.

[13]  P. Devreotes,et al.  Adenylyl cyclase A expression is tip-specific in Dictyostelium slugs and directs StatA nuclear translocation and CudA gene expression. , 2001, Developmental biology.

[14]  M. Katoh,et al.  Spatial expression patterns of genes involved in cyclic AMP responses in Dictyostelium discoideum development , 2001, Development, growth & differentiation.

[15]  E. Avvedimento,et al.  The biological functions of A-kinase anchor proteins. , 2001, Journal of molecular biology.

[16]  L. Langeberg,et al.  mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module , 2001, The EMBO journal.

[17]  J. Robishaw,et al.  Heterotrimeric G-protein βγ-dimers in growth and differentiation , 2001, Oncogene.

[18]  P. V. van Haastert,et al.  Identification and characterization of DdPDE3, a cGMP-selective phosphodiesterase from Dictyostelium. , 2001, The Biochemical journal.

[19]  S. Schuster,et al.  Osmotic stress response in Dictyostelium is mediated by cAMP , 2000, The EMBO journal.

[20]  G. Shaulsky,et al.  The internal phosphodiesterase RegA is essential for the suppression of lateral pseudopods during Dictyostelium chemotaxis. , 2000, Molecular biology of the cell.

[21]  M. Cann,et al.  Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor. , 2000, Science.

[22]  C. Anjard,et al.  An adenylyl cyclase that functions during late development of Dictyostelium. , 1999, Development.

[23]  R. Kay,et al.  The RdeA-RegA System, a Eukaryotic Phospho-relay Controlling cAMP Breakdown* , 1999, The Journal of Biological Chemistry.

[24]  R. Firtel,et al.  A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium. , 1999, Molecular biology of the cell.

[25]  D. Cotter,et al.  High cAMP in spores of Dictyostelium discoideum: association with spore dormancy and inhibition of germination. , 1999, Microbiology.

[26]  A. Dunbar,et al.  Ammonium phosphate in sori of Dictyostelium discoideum promotes spore dormancy through stimulation of the osmosensor ACG. , 1999, Microbiology.

[27]  M. Meima,et al.  Fingerprinting of adenylyl cyclase activities during Dictyostelium development indicates a dominant role for adenylyl cyclase B in terminal differentiation. , 1999, Developmental biology.

[28]  A. Kuspa,et al.  Starvation promotes Dictyostelium development by relieving PufA inhibition of PKA translation through the YakA kinase pathway. , 1999, Development.

[29]  G. Shaulsky,et al.  SDF-2 Induction of Terminal Differentiation in Dictyostelium discoideum Is Mediated by the Membrane-Spanning Sensor Kinase DhkA , 1999, Molecular and Cellular Biology.

[30]  M. Ohmori,et al.  Activation of a Cyanobacterial Adenylate Cyclase, CyaC, by Autophosphorylation and a Subsequent Phosphotransfer Reaction* , 1999, The Journal of Biological Chemistry.

[31]  J. Hurley.  The adenylyl and guanylyl cyclase superfamily. , 1998, Current opinion in structural biology.

[32]  M. Laub,et al.  A molecular network that produces spontaneous oscillations in excitable cells of Dictyostelium. , 1998, Molecular biology of the cell.

[33]  J. Gross,et al.  A Novel Adenylyl Cyclase Detected in Rapidly Developing Mutants of Dictyostelium * , 1998, The Journal of Biological Chemistry.

[34]  B. Mykytka,et al.  The histidine kinase dhkC regulates the choice between migrating slugs and terminal differentiation in Dictyostelium discoideum. , 1998, Developmental biology.

[35]  P. Devreotes,et al.  Functional Promiscuity of Gene Regulation by Serpentine Receptors in Dictyostelium discoideum , 1998, Molecular and Cellular Biology.

[36]  C. Saxe,et al.  SCAR, a WASP-related Protein, Isolated as a Suppressor of Receptor Defects in Late Dictyostelium Development , 1998, The Journal of cell biology.

[37]  P. Devreotes,et al.  Temperature‐sensitive Gβ mutants discriminate between G protein‐dependent and ‐independent signaling mediated by serpentine receptors , 1998, The EMBO journal.

[38]  R. Firtel,et al.  Developmentally and spatially regulated activation of a Dictyostelium STAT protein by a serpentine receptor , 1998, The EMBO journal.

[39]  P. V. van Haastert,et al.  A novel Myb homolog initiates Dictyostelium development by induction of adenylyl cyclase expression. , 1998, Genes & development.

[40]  P. Newell,et al.  Evidence that the RdeA protein is a component of a multistep phosphorelay modulating rate of development in Dictyostelium , 1998, The EMBO journal.

[41]  G. Cavet,et al.  An intersection of the cAMP/PKA and two‐component signal transduction systems in Dictyostelium , 1998, The EMBO journal.

[42]  P. Devreotes,et al.  Switching of chemoattractant receptors programs development and morphogenesis in Dictyostelium: receptor subtypes activate common responses at different agonist concentrations. , 1998, Developmental biology.

[43]  M. Zinda,et al.  The hybrid histidine kinase dhkB regulates spore germination in Dictyostelium discoideum. , 1998, Developmental biology.

[44]  M. Caron,et al.  G protein-coupled receptor adaptation mechanisms. , 1998, Seminars in cell & developmental biology.

[45]  W F Loomis,et al.  A cAMP-phosphodiesterase controls PKA-dependent differentiation. , 1998, Development.

[46]  C. Anjard,et al.  Signal Transduction Pathways Leading to Spore Differentiation inDictyostelium discoideum , 1998 .

[47]  Heidi E. Hamm,et al.  The Many Faces of G Protein Signaling* , 1998, The Journal of Biological Chemistry.

[48]  P. Devreotes,et al.  A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium. , 1997, Genes & development.

[49]  F. Siegert,et al.  Null mutations of the Dictyostelium cyclic nucleotide phosphodiesterase gene block chemotactic cell movement in developing aggregates. , 1997, Developmental biology.

[50]  K. Yeh,et al.  A cyanobacterial phytochrome two-component light sensory system. , 1997, Science.

[51]  J. Williams,et al.  cudA: a Dictyostelium gene with pleiotropic effects on cellular differentiation and slug behaviour. , 1997, Development.

[52]  G. Milligan,et al.  Tailoring cAMP-signalling responses through isoform multiplicity. , 1997, Trends in biochemical sciences.

[53]  R. Firtel,et al.  Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development in Dictyostelium. , 1997, Developmental biology.

[54]  M. Caterina,et al.  Random Mutagenesis of the cAMP Chemoattractant Receptor, cAR1, of Dictyostelium , 1997, The Journal of Biological Chemistry.

[55]  M. Caterina,et al.  Random mutagenesis of the cAMP chemoattractant receptor, cAR1, of Dictyostelium. Mutant classes that cause discrete shifts in agonist affinity and lock the receptor in a novel activational intermediate. , 1997, The Journal of biological chemistry.

[56]  G. Shaulsky,et al.  Developmental signal transduction pathways uncovered by genetic suppressors. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[57]  D. Cotter,et al.  Adenylyl Cyclase G, an Osmosensor Controlling Germination of Dictyostelium Spores* , 1996, The Journal of Biological Chemistry.

[58]  P. Devreotes,et al.  Constitutively Active Adenylyl Cyclase Mutant Requires Neither G Proteins nor Cytosolic Regulators* , 1996, The Journal of Biological Chemistry.

[59]  Stefan Dipl.-Ing. Schuster,et al.  The hybrid histidine kinase DokA is part of the osmotic response system of Dictyostelium. , 1996, The EMBO journal.

[60]  P. Devreotes,et al.  The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium , 1996, Current Biology.

[61]  R. Firtel,et al.  Seven Helix Chemoattractant Receptors Transiently Stimulate Mitogen-activated Protein Kinase in Dictyostelium , 1996, The Journal of Biological Chemistry.

[62]  R. Gomer,et al.  PSF and CMF, autocrine factors that regulate gene expression during growth and early development ofDictyostelium , 1995, Experientia.

[63]  P. Schaap,et al.  cAMP‐dependent protein kinase activity is essential for preaggregative gene expression in Dictyostelium , 1995, FEBS letters.

[64]  P. Devreotes,et al.  The G protein beta subunit is essential for multiple responses to chemoattractants in Dictyostelium , 1995, The Journal of cell biology.

[65]  M. Caterina,et al.  Seven Helix cAMP Receptors Stimulate Ca Entry in the Absence of Functional G Proteins in Dictyostelium(*) , 1995, The Journal of Biological Chemistry.

[66]  W F Loomis,et al.  A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium , 1995, The Journal of cell biology.

[67]  D. L. Richardson,et al.  Expression of cAMP-dependent protein kinase in prespore cells is sufficient to induce spore cell differentiation in Dictyostelium. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[68]  G. Shaulsky,et al.  CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium , 1994, The Journal of cell biology.

[69]  J. Louis,et al.  The cAMP receptor CAR4 regulates axial patterning and cellular differentiation during late development of Dictyostelium. , 1994, Genes & development.

[70]  P. Devreotes,et al.  Identification of CRAC, a cytosolic regulator required for guanine nucleotide stimulation of adenylyl cyclase in Dictyostelium. , 1994, The Journal of biological chemistry.

[71]  H. Othmer,et al.  A G protein-based model of adaptation in Dictyostelium discoideum. , 1994, Mathematical biosciences.

[72]  P. Devreotes,et al.  Extracellular cAMP is sufficient to restore developmental gene expression and morphogenesis in Dictyostelium cells lacking the aggregation adenylyl cyclase (ACA). , 1993, Genes & development.

[73]  C. Anjard,et al.  Induction of terminal differentiation of Dictyostelium by cAMP-dependent protein kinase and opposing effects of intracellulr and extracellular cAMP on stalk cell differentiation. , 1993, Development.

[74]  R. Firtel,et al.  cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development. , 1993, Development.

[75]  Jeffrey G. Williams,et al.  Activation of the prespore and spore cell pathway of Dictyostelium differentiation by cAMP‐dependent protein kinase and evidence for its upstream regulation by ammonia. , 1993, The EMBO journal.

[76]  P. Devreotes,et al.  A G-protein beta-subunit is essential for Dictyostelium development. , 1993, Genes & development.

[77]  R. Kessin,et al.  The role of the cyclic nucleotide phosphodiesterase of Dictyostelium discoideum during growth, aggregation, and morphogenesis: overexpression and localization studies with the separate promoters of the pde. , 1993, Developmental biology.

[78]  P. Devreotes,et al.  The surface cyclic AMP receptors, cAR1, cAR2, and cAR3, promote Ca2+ influx in Dictyostelium discoideum by a G alpha 2-independent mechanism. , 1993, Molecular biology of the cell.

[79]  R. L. Johnson,et al.  Identification and targeted gene disruption of cAR3, a cAMP receptor subtype expressed during multicellular stages of Dictyostelium development. , 1993, Genes & development.

[80]  J. Louis,et al.  CAR2, a prestalk cAMP receptor required for normal tip formation and late development of Dictyostelium discoideum. , 1993, Genes & development.

[81]  A. Kuspa,et al.  Tagging developmental genes in Dictyostelium by restriction enzyme-mediated integration of plasmid DNA. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[82]  C J Weijer,et al.  Three-dimensional scroll waves organize Dictyostelium slugs. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[83]  J. Williams,et al.  Culmination in dictyostelium is regulated by the cAMP-dependent protein kinase , 1992, Cell.

[84]  Peter N. Devreotes,et al.  Structurally distinct and stage-specific adenylyl cyclase genes play different roles in dictyostelium development , 1992, Cell.

[85]  R. Kay,et al.  Mutation of protein kinase A causes heterochronic development of Dictyostelium , 1992, Nature.

[86]  B Jastorff,et al.  The cyclic nucleotide specificity of three cAMP receptors in Dictyostelium. , 1992, The Journal of biological chemistry.

[87]  R. Kessin,et al.  The cyclic nucleotide phosphodiesterase gene of Dictyostelium discoideum contains three promoters specific for growth, aggregation, and late development , 1990, Molecular and cellular biology.

[88]  R. Firtel,et al.  Regulation and function of Gα protein subunits in Dictyostelium , 1989, Cell.

[89]  P. Schaap,et al.  Ammonia depletion and DIF trigger stalk cell intact Dictyostelium discoideum slugs , 1989 .

[90]  R. Kessin,et al.  Disruption of Dictyostelium discoideum morphogenesis by overproduction of cAMP phosphodiesterase. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[91]  P. Devreotes,et al.  A chemoattractant receptor controls development in Dictyostelium discoideum. , 1988, Science.

[92]  R. Kay,et al.  Cyclic AMP is an inhibitor of stalk cell differentiation in Dictyostelium discoideum. , 1988, Developmental biology.

[93]  A Goldbeter,et al.  A Model Based on Receptor Desensitization for Cyclic AMP Signaling in Dictyostelium Cells. , 1987, Biophysical journal.

[94]  M. Wigler,et al.  Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae , 1987, Molecular and cellular biology.

[95]  T. Chambers,et al.  Translocation of cAMP-dependent protein kinase to the nucleus during development of Dictyostelium discoideum. , 1986, Developmental biology.

[96]  R. van Driel,et al.  Induction of post-aggregative differentiation in Dictyostelium discoideum by cAMP. Evidence of involvement of the cell surface cAMP receptor. , 1985, Experimental cell research.

[97]  P. Devreotes,et al.  Identification and cyclic AMP-induced modification of the cyclic AMP receptor in Dictyostelium discoideum. , 1985, The Journal of biological chemistry.

[98]  R. Kay.  cAMP and spore differentiation in Dictyostelium discoideum. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[99]  P. Newell,et al.  Streamers: chemotactic mutants of Dictyostelium discoideum with altered cyclic GMP metabolism. , 1981, Journal of general microbiology.

[100]  R. Kessin,et al.  The cyclic nucleotide phosphodiesterase inhibitory protein of Dictyostelium discoideum. Purification and characterization. , 1981, The Journal of biological chemistry.

[101]  R. Kessin,et al.  Binding of inhibitor alters kinetic and physical properties of extracellular cyclic AMP phosphodiesterase from Dictyostelium discoideum. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[102]  P. Devreotes,et al.  I. a Technique to Monitor Responses to Controlled Stimuli , 1979 .

[103]  M. Darmon,et al.  The role of phosphodiesterase in aggregation of Dictyostelium discoideum. , 1978, Journal of Cell Science.

[104]  M. Sussman,et al.  Ammonia determines the choice of morphogenetic pathways in Dictyostelium discoideum. , 1977, Journal of molecular biology.

[105]  G. Gerisch.  Extracellular cyclic-amp phosphodiesterase regulation in agar plate cultures of Dictyostelium discoideum. , 1976, Cell differentiation.

[106]  G. Gerisch,et al.  Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells , 1975, Nature.

[107]  H. Schwarz,et al.  Membrane-bound cyclic AMP phosphodiesterase in chemotactically responding cells of Dictyostelium discoideum. , 1972, European journal of biochemistry.

[108]  G. Gerisch,et al.  Regulation of extracellular cyclic-AMP-phosphodiesterase activity during development of Dictyostelium discoideum. , 1971, Biochemical and biophysical research communications.

[109]  J. Bonner,et al.  The acrasin activity of adenosine-3',5'-cyclic phosphate. , 1967, Proceedings of the National Academy of Sciences of the United States of America.

[110]  P. Devreotes,et al.  University of Groningen Phosphorylation of chemoattractant receptors is not essential for chemotaxis or termination of G-protein-mediated responses , 2017 .

[111]  P. Schaap,et al.  Ammonia depletion and DIF trigger stalk cell differentiation in intact Dictyostelium discoideum slugs , 2005 .

[112]  A. Kimmel,et al.  Galpha-mediated inhibition of developmental signal response. , 2002, Current biology : CB.

[113]  C. Anjard,et al.  Signal transduction pathways leading to spore differentiation in Dictyostelium discoideum. , 1998, Developmental biology.

[114]  W. Nellen,et al.  Antagonistic effects of signal transduction by intracellular and extracellular cAMP on gene regulation in Dictyostelium. , 1996, Molecular biology of the cell.

[115]  A. Danchin.  Phylogeny of adenylyl cyclases. , 1993, Advances in second messenger and phosphoprotein research.

[116]  L. Wu,et al.  A developmentally regulated and cAMP-repressible gene of Dictyostelium discoideum: cloning and expression of the gene encoding cyclic nucleotide phosphodiesterase inhibitor. , 1990, Gene.

[117]  R. Firtel,et al.  Regulation and function of G alpha protein subunits in Dictyostelium. , 1989, Cell.

[118]  J. de Gunzburg,et al.  Cloning and cDNA sequence of the regulatory subunit of cAMP-dependent protein kinase from Dictyostelium discoideum. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[119]  P. Devreotes,et al.  Surface Receptor Mediated Activation and Adaptation of Adenylate Cyclase in Dictyostelium discoideum , 1987 .

[120]  K. Yanagisawa,et al.  A new class of rapidly developing mutants in Dictyostelium discoideum: implications for cyclic AMP metabolism and cell differentiation. , 1983, Developmental biology.