Development of New and Selective Trypanosoma cruzi trans‐Sialidase Inhibitors from Sulfonamide Chalcones and Their Derivatives
暂无分享,去创建一个
S. Withers | K. Park | H. Ryu | J. Shim | Jin Hyo Kim
[1] A. D. de Lera,et al. Inhibition of IkappaB kinase-beta and anticancer activities of novel chalcone adamantyl arotinoids. , 2008, Journal of medicinal chemistry.
[2] S. Withers,et al. A New Generation of SpecificTrypanosoma cruzi trans-Sialidase Inhibitors , 2008 .
[3] S. Withers,et al. A new generation of specific Trypanosoma cruzi trans-sialidase inhibitors. , 2008, Angewandte Chemie.
[4] Andrew G. Watts,et al. Kinetic and mechanistic analysis of Trypanosoma cruzi trans-sialidase reveals a classical ping-pong mechanism with acid/base catalysis. , 2008, Biochemistry.
[5] S. Withers,et al. The Search for Novel Human Pancreatic α‐Amylase Inhibitors: High‐Throughput Screening of Terrestrial and Marine Natural Product Extracts , 2008, Chembiochem : a European journal of chemical biology.
[6] B. Bandgar,et al. In-vitro evaluation of selected chalcones for antioxidant activity , 2008 .
[7] H. Streicher,et al. Galactose‐Phosphonates as Mimetics of the Sialyltransfer by Trypanosomal Sialidases , 2007 .
[8] P. Alzari,et al. Benzoic acid and pyridine derivatives as inhibitors of Trypanosoma cruzi trans-sialidase. , 2007, Bioorganic & medicinal chemistry.
[9] A. Frasch,et al. Trypanosoma cruzi surface mucins: host-dependent coat diversity , 2006, Nature Reviews Microbiology.
[10] H. Streicher,et al. Building a successful structural motif into sialylmimetics-cyclohexenephosphonate monoesters as pseudo-sialosides with promising inhibitory properties. , 2006, Bioorganic & medicinal chemistry.
[11] Jin Hyo Kim,et al. Sulfonamide chalcone as a new class of α-glucosidase inhibitors , 2005 .
[12] M. Kiefel,et al. NMR spectroscopic and molecular modeling investigations of the trans-sialidase from Trypanosoma cruzi. , 2004, Glycobiology.
[13] Andrew G. Watts,et al. Structural insights into the catalytic mechanism of Trypanosoma cruzi trans-sialidase. , 2004, Structure.
[14] Jeh-Jeng Wang,et al. Synthesis and Anti-inflammatory Effect of Chalcones and Related Compounds , 2004, Pharmaceutical Research.
[15] Andrew G. Watts,et al. Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile. , 2003, Journal of the American Chemical Society.
[16] H. Cerecetto,et al. Chemotherapy of Chagas' disease: status and new developments. , 2002, Current topics in medicinal chemistry.
[17] Pedro M Alzari,et al. The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis. , 2002, Molecular cell.
[18] A. Frasch,et al. Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi. , 2000, Parasitology today.
[19] R. Laughlin. The basicity of aliphatic sulfonamides , 1967 .
[20] A. Cammarata,et al. Observations concerning the correlation of in vitro sulfonamide activity with pKa and the Hammett values. , 1967, Journal of pharmaceutical sciences.