Morphological operation and scaled Réyni entropy based approach for masses detection in mammograms

Detection of suspicious masses in mammograms play a vital role in early diagnosis of breast cancer, to reduce the death rate among women. The presence of masses and calcification’s in mammograms is distinguishing signs for breast cancer diagnosis. But in some cases, due to contrast variation, fuzzy boundaries and presence of noise in mammograms, segmentation and detection of masses is challenging assignment. This paper presents a new segmentation approach to detect masses in mammographic images. The proposed approach consist of artifacts elimination and pectoral region extraction, suspicious mass enhancement using dual morphological operation technique and finally, extraction of Regions of Interest (ROIs) from background using scaled Réyni entropy. The proposed system has been tested on two data-sets i.e. mini- Mammographic Image Analysis Society (mini-MIAS) and Digital Database for Screening Mammography (DDSM), over 50 and 90 mammograms respectively. Performance achieved with proposed system in terms of True Positive Fraction (TPF) yields 93.2% and 93.9% respectively, at the rate of 1.48 and 0.74 average False Positive per Image (FP/I), tested on both Cranio-Caudal (CC) and Medio-Lateral Oblique (MLO) views. The obtained experimental results demonstrates that proposed method gives improved results for mass detection and can be useful for radiologists in diagnosis of breast cancer at early stage.

[1]  Amar Partap Singh Pharwaha,et al.  Shannon and Non-Shannon Measures of Entropy for Statistical Texture Feature Extraction in Digitized Mammograms , 2009 .

[2]  Shengjie Li,et al.  Recent Advances , 2018, Journal of Optimization Theory and Applications.

[3]  Marcelo Zanchetta do Nascimento,et al.  Segmentation and detection of breast cancer in mammograms combining wavelet analysis and genetic algorithm , 2014, Comput. Methods Programs Biomed..

[4]  Rafael C. González,et al.  Digital image processing using MATLAB , 2006 .

[5]  Bhupendra Gupta,et al.  A tool supported approach for brightness preserving contrast enhancement and mass segmentation of mammogram images using histogram modified grey relational analysis , 2017, Multidimens. Syst. Signal Process..

[6]  Pinar Balci,et al.  Breast mass contour segmentation algorithm in digital mammograms , 2013, Comput. Methods Programs Biomed..

[7]  Mariusz Bajger,et al.  Two graph theory based methods for identifying the pectoral muscle in mammograms , 2007, Pattern Recognit..

[8]  Murk J. Bottema,et al.  Texture and region dependent breast cancer risk assessment from screening mammograms , 2014, Pattern Recognit. Lett..

[9]  Arnau Oliver,et al.  A review of automatic mass detection and segmentation in mammographic images , 2010, Medical Image Anal..

[10]  C. K. Chua,et al.  Computer-Aided Breast Cancer Detection Using Mammograms: A Review , 2013, IEEE Reviews in Biomedical Engineering.

[11]  Vasif V. Nabiyev,et al.  A novel automatic suspicious mass regions identification using Havrda & Charvat entropy and Otsu's N thresholding , 2014, Comput. Methods Programs Biomed..

[12]  Jean Serra,et al.  Image Analysis and Mathematical Morphology , 1983 .

[13]  Yongyi Yang,et al.  Computer-Aided Detection and Diagnosis of Breast Cancer With Mammography: Recent Advances , 2009, IEEE Transactions on Information Technology in Biomedicine.

[15]  Alima Damak Masmoudi,et al.  An efficient microcalcifications detection based on dual spatial/spectral processing , 2017, Multimedia Tools and Applications.

[16]  Pierre Soille,et al.  Morphological Image Analysis: Principles and Applications , 2003 .

[17]  A. Rényi On Measures of Entropy and Information , 1961 .

[18]  Korris Fu-Lai Chung,et al.  Note on the equivalence relationship between Renyi-entropy based and Tsallis-entropy based image thresholding , 2005, Pattern Recognit. Lett..

[19]  Manish Kumar Bajpai,et al.  An efficient algorithm for mass detection and shape analysis of different masses present in digital mammograms , 2017, Multimedia Tools and Applications.

[20]  Hong Liu,et al.  Marker-Controlled Watershed for Lesion Segmentation in Mammograms , 2011, Journal of Digital Imaging.

[21]  Georgia D. Tourassi,et al.  A Concentric Morphology Model for the Detection of Masses in Mammography , 2007, IEEE Transactions on Medical Imaging.

[22]  V. R. Thool,et al.  Mass Detection in Mammographic Images Using Wavelet Processing and Adaptive Threshold Technique , 2016, Journal of Medical Systems.

[23]  Jagat Narain Kapur,et al.  Measures of information and their applications , 1994 .

[24]  Aize Cao,et al.  Robust information clustering incorporating spatial information for breast mass detection in digitized mammograms , 2008, Comput. Vis. Image Underst..

[25]  J. Anitha,et al.  A dual stage adaptive thresholding (DuSAT) for automatic mass detection in mammograms , 2017, Comput. Methods Programs Biomed..

[26]  Robert J. Schalkoff,et al.  Digital Image Processing and Computer Vision , 1989 .

[27]  Heng-Da Cheng,et al.  Computer-aided detection and classification of microcalcifications in mammograms: a survey , 2003, Pattern Recognit..

[28]  Anselmo Cardoso de Paiva,et al.  Automatic mass detection in mammography images using particle swarm optimization and functional diversity indexes , 2017, Multimedia Tools and Applications.

[29]  V. R. Thool,et al.  Intensity Based Automatic Boundary Identification of Pectoral Muscle in Mammograms , 2016 .

[30]  Yongyi Yang,et al.  A bilateral analysis scheme for false positive reduction in mammogram mass detection , 2015, Comput. Biol. Medicine.

[31]  Arianna Mencattini,et al.  Mammographic Images Enhancement and Denoising for Breast Cancer Detection Using Dyadic Wavelet Processing , 2008, IEEE Transactions on Instrumentation and Measurement.

[32]  Jae Young Choi,et al.  A generalized multiple classifier system for improving computer-aided classification of breast masses in mammography , 2015 .

[33]  Robert C. Wolpert,et al.  A Review of the , 1985 .

[34]  Prem Kumar Kalra,et al.  An automatic method to enhance microcalcifications using Normalized Tsallis entropy , 2010, Signal Process..

[35]  Gulzar A. Khuwaja,et al.  Bi-modal breast cancer classification system , 2004, Pattern Analysis and Applications.

[36]  Gamil Abdel-Azim,et al.  A novel statistical approach for detection of suspicious regions in digital mammogram , 2013 .

[37]  Fei Li,et al.  Detection of Suspicious Lesions by Adaptive Thresholding Based on Multiresolution Analysis in Mammograms , 2011, IEEE Transactions on Instrumentation and Measurement.

[38]  Wei-Yen Hsu,et al.  Improved watershed transform for tumor segmentation: Application to mammogram image compression , 2012, Expert Syst. Appl..

[39]  Martin Kom,et al.  Automated detection of masses in mammograms by local adaptive thresholding , 2007, Comput. Biol. Medicine.

[40]  A. Elmaghraby,et al.  Characterization of ultrasonic backscatter based on generalized entropy , 2002, Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology.

[41]  Shen-Chuan Tai,et al.  An Automatic Mass Detection System in Mammograms Based on Complex Texture Features , 2014, IEEE Journal of Biomedical and Health Informatics.

[42]  Masayuki Murakami,et al.  Computerized detection of malignant tumors on digital mammograms , 1999, IEEE Transactions on Medical Imaging.