Gene expression analysis indicates CB1 receptor upregulation in the hippocampus and neurotoxic effects in the frontal cortex 3 weeks after single-dose MDMA administration in Dark Agouti rats

[1]  M. Dalva,et al.  Ephrin regulation of synapse formation, function and plasticity , 2012, Molecular and Cellular Neuroscience.

[2]  J. Delgado-García,et al.  Involvement of cannabinoid CB1 receptor in associative learning and in hippocampal CA3-CA1 synaptic plasticity. , 2012, Cerebral cortex.

[3]  Joanna Seniów,et al.  Executive dysfunctions and frontal syndromes. , 2012, Frontiers of neurology and neuroscience.

[4]  P. Robledo,et al.  Active and passive MDMA (‘ecstasy’) intake induces differential transcriptional changes in the mouse brain , 2012, Genes, brain, and behavior.

[5]  G. Juhász,et al.  Personalized medicine can pave the way for the safe use of CB₁ receptor antagonists. , 2011, Trends in pharmacological sciences.

[6]  D. Harper,et al.  The effects of binge MDMA on acquisition and reversal learning in a radial-arm maze task , 2011, Neurobiology of Learning and Memory.

[7]  K. Lesch,et al.  Ultrastructural characterization of tryptophan hydroxylase 2-specific cortical serotonergic fibers and dorsal raphe neuronal cell bodies after MDMA treatment in rat , 2011, Psychopharmacology.

[8]  Gary D Bader,et al.  Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation , 2010, PloS one.

[9]  R. Hampson,et al.  Cannabinoid and cholinergic systems interact during performance of a short-term memory task in the rat. , 2010, Learning & memory.

[10]  A. Liou,et al.  Heat shock proteins: Cellular and molecular mechanisms in the central nervous system , 2010, Progress in Neurobiology.

[11]  L. Hunyady,et al.  Elevated BDNF protein level in cortex but not in hippocampus of MDMA-treated Dark Agouti rats: A potential link to the long-term recovery of serotonergic axons , 2010, Neuroscience Letters.

[12]  A. Brass,et al.  Differential gene expression in a rat model of depression based on persistent differences in exploratory activity , 2010, European Neuropsychopharmacology.

[13]  G. Hammond,et al.  Differential Effects of Ecstasy on Short-Term and Working Memory: A Meta-Analysis , 2010, Neuropsychology Review.

[14]  D. Biezonski,et al.  Effects of 3,4‐methylenedioxymethamphetamine (MDMA) on serotonin transporter and vesicular monoamine transporter 2 protein and gene expression in rats: implications for MDMA neurotoxicity , 2010, Journal of neurochemistry.

[15]  G. Bagdy,et al.  Activation of 5-HT3 receptors leads to altered responses 6 months after MDMA treatment , 2010, Journal of Neural Transmission.

[16]  J. Bolz,et al.  Structural alterations of spiny stellate cells in the somatosensory cortex in ephrin‐A5‐deficient mice , 2009, The Journal of comparative neurology.

[17]  Tin Wee Tan,et al.  A proposed minimum skill set for university graduates to meet the informatics needs and challenges of the "-omics" era , 2009, BMC Genomics.

[18]  B. Lu,et al.  New Insights in the Biology of BDNF Synthesis and Release: Implications in CNS Function , 2009, The Journal of Neuroscience.

[19]  Neil D. Lawrence,et al.  puma: a Bioconductor package for propagating uncertainty in microarray analysis , 2009, BMC Bioinformatics.

[20]  Ronald M. Salomon,et al.  Prior MDMA (Ecstasy) use is associated with increased basal ganglia–thalamocortical circuit activation during motor task performance in humans: An fMRI study , 2009, NeuroImage.

[21]  R. Seitz,et al.  Value judgments and self-control of action: The role of the medial frontal cortex , 2009, Brain Research Reviews.

[22]  Andreas Meisel,et al.  Molecular and Cellular Mechanisms of Ecstasy-Induced Neurotoxicity: An Overview , 2009, Molecular Neurobiology.

[23]  B. Gorzalka,et al.  Impairments in endocannabinoid signaling and depressive illness. , 2009, JAMA.

[24]  G. Bagdy,et al.  MDMA treatment 6 months earlier attenuates the effects of CP-94,253, a 5-HT1B receptor agonist, on motor control but not sleep inhibition , 2008, Brain Research.

[25]  Gyorgy Bagdy,et al.  Decrease in REM latency and changes in sleep quality parallel serotonergic damage and recovery after MDMA: a longitudinal study over 180 days. , 2008, The international journal of neuropsychopharmacology.

[26]  Marilyn A Huestis,et al.  Physiological and Subjective Responses to Controlled Oral 3,4-Methylenedioxymethamphetamine Administration , 2008, Journal of clinical psychopharmacology.

[27]  P. Vogel,et al.  Learning and memory impairment in Eph receptor A6 knockout mice , 2008, Neuroscience Letters.

[28]  J. A. López-Moreno,et al.  The pharmacology of the endocannabinoid system: functional and structural interactions with other neurotransmitter systems and their repercussions in behavioral addiction , 2008, Addiction biology.

[29]  K. Christian,et al.  BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory? , 2008, Neurobiology of Learning and Memory.

[30]  Michael L. Creech,et al.  Integration of biological networks and gene expression data using Cytoscape , 2007, Nature Protocols.

[31]  K. Murai,et al.  The EphA4 receptor regulates dendritic spine remodeling by affecting β1-integrin signaling pathways , 2007, The Journal of cell biology.

[32]  Michela Matteoli,et al.  Hardwiring the Brain: Endocannabinoids Shape Neuronal Connectivity , 2007, Science.

[33]  M. Palkovits,et al.  Single dose of MDMA causes extensive decrement of serotoninergic fibre density without blockage of the fast axonal transport in Dark Agouti rat brain and spinal cord , 2007, Neuropathology and applied neurobiology.

[34]  Allan R. Jones,et al.  Genome-wide atlas of gene expression in the adult mouse brain , 2007, Nature.

[35]  C. Adori,et al.  Damage of serotonergic axons and immunolocalization of Hsp27, Hsp72, and Hsp90 molecular chaperones after a single dose of MDMA administration in Dark Agouti rat: Temporal, spatial, and cellular patterns , 2006, The Journal of comparative neurology.

[36]  Rebeca Martínez-Turrillas,et al.  Differential effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) on BDNF mRNA expression in rat frontal cortex and hippocampus , 2006, Neuroscience Letters.

[37]  H. J. Olverman,et al.  Persistent cerebrovascular effects of MDMA and acute responses to the drug , 2006, The European journal of neuroscience.

[38]  C. Marsden,et al.  Ecstasy: Are animal data consistent between species and can they translate to humans? , 2006, Journal of psychopharmacology.

[39]  J. Mesirov,et al.  From the Cover: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005 .

[40]  Zsolt Szabo,et al.  Quantitative PET Studies of the Serotonin Transporter in MDMA Users and Controls Using [11C]McN5652 and [11C]DASB , 2005, Neuropsychopharmacology.

[41]  M. Colado,et al.  Studies on the effect of MDMA (‘ecstasy’) on the body temperature of rats housed at different ambient room temperatures , 2005, British journal of pharmacology.

[42]  T. Robbins,et al.  Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates , 2004, Neuroscience & Biobehavioral Reviews.

[43]  Jean YH Yang,et al.  Bioconductor: open software development for computational biology and bioinformatics , 2004, Genome Biology.

[44]  J. Mackey,et al.  Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene , 2004, BMC pharmacology.

[45]  R. Jakus,et al.  Effects of a single dose of 3,4-methylenedioxymethamphetamine on circadian patterns, motor activity and sleep in drug-naive rats and rats previously exposed to MDMA , 2004, Psychopharmacology.

[46]  Pilar Andrés,et al.  Frontal Cortex as the Central Executive of Working Memory: Time to Revise Our View , 2003, Cortex.

[47]  P. Shannon,et al.  Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.

[48]  G. Gerra,et al.  Hypothalamic–pituitary–adrenal axis responses to stress in subjects with 3,4-methylenedioxy-methamphetamine (‘ecstasy’) use history: correlation with dopamine receptor sensitivity , 2003, Psychiatry Research.

[49]  M. Colado,et al.  The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) , 2003, Pharmacological Reviews.

[50]  M. Hofker.  Faculty Opinions recommendation of PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. , 2003 .

[51]  K. Murai,et al.  Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling , 2003, Nature Neuroscience.

[52]  A I Saeed,et al.  TM4: a free, open-source system for microarray data management and analysis. , 2003, BioTechniques.

[53]  N. Thiriet,et al.  Analysis of Ecstasy (MDMA)‐induced transcriptional responses in the rat cortex , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[54]  M. Herrero,et al.  Functional anatomy of thalamus and basal ganglia , 2002, Child’s Nervous System.

[55]  M. Colado,et al.  The pharmacology of the acute hyperthermic response that follows administration of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) to rats , 2002, British journal of pharmacology.

[56]  Morris Freedman,et al.  Frontal lobe functions , 2001, Current neurology and neuroscience reports.

[57]  S A Deadwyler,et al.  Cannabinoids Reveal the Necessity of Hippocampal Neural Encoding for Short-Term Memory in Rats , 2000, The Journal of Neuroscience.

[58]  J. Duncan,et al.  Common regions of the human frontal lobe recruited by diverse cognitive demands , 2000, Trends in Neurosciences.

[59]  A. Parrott,et al.  Psychobiological problems in heavy 'ecstasy' (MDMA) polydrug users. , 2000, Drug and alcohol dependence.

[60]  B. Postle,et al.  Prefrontal cortical contributions to working memory: evidence from event-related fMRI studies , 2000, Experimental Brain Research.

[61]  M. Ashburner,et al.  Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.

[62]  D. Murphy,et al.  Altered neuroendocrine and behavioral responses to m-chlorophenylpiperazine in 3,4-methylenedioxymethamphetamine (MDMA) users , 1999, Psychopharmacology.

[63]  J. Winer,et al.  Regulation of Learning by EphA Receptors: a Protein Targeting Study , 1999, The Journal of Neuroscience.

[64]  R. Hampson,et al.  Cannabinoids, hippocampal function and memory. , 1999, Life sciences.

[65]  L. Parsons,et al.  Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness. , 1999, The American journal of psychiatry.

[66]  L. Acsády,et al.  Structural basis of the cholinergic and serotonergic modulation of GABAergic neurons in the hippocampus , 1999, Neurochemistry International.

[67]  S. Petersen,et al.  Frontal cortex contributes to human memory formation , 1999, Nature Neuroscience.

[68]  D. Cerretti,et al.  Ephrin-dependent growth and pruning of hippocampal axons. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[69]  M. Colado,et al.  Studies on the role of dopamine in the degeneration of 5‐HT nerve endings in the brain of Dark Agouti rats following 3,4‐methylenedioxymethamphetamine (MDMA or ‘ecstasy’) administration , 1999, British journal of pharmacology.

[70]  D. Botstein,et al.  Cluster analysis and display of genome-wide expression patterns. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[71]  F. Vollenweider,et al.  Psychological and Cardiovascular Effects and Short-Term Sequelae of MDMA (“Ecstasy”) in MDMA-Naïve Healthy Volunteers , 1998, Neuropsychopharmacology.

[72]  L. Seiden,et al.  Small Changes in Ambient Temperature Cause Large Changes in 3,4-Methylenedioxymethamphetamine (MDMA)-Induced Serotonin Neurotoxicity and Core Body Temperature in the Rat , 1998, The Journal of Neuroscience.

[73]  H Honda,et al.  Topographic mapping in the retinotectal projection by means of complementary ligand and receptor gradients: a computer simulation study. , 1998, Journal of theoretical biology.

[74]  M. Greene,et al.  Cloning of m-ehk2 from the murine inner ear, an eph family receptor tyrosine kinase expressed in the developing and adult cochlea. , 1996, DNA and cell biology.

[75]  W. Slikker,et al.  Age-dependent sensitivity of rats to the long-term effects of the serotonergic neurotoxicant (+/-)-3,4-methylenedioxymethamphetamine (MDMA) correlates with the magnitude of the MDMA-induced thermal response. , 1995, The Journal of pharmacology and experimental therapeutics.

[76]  A. Lichtman,et al.  Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats , 1995, Psychopharmacology.

[77]  J. O'Callaghan,et al.  Effects of 3,4-methylenedioxymethamphetamine on autonomic thermoregulatory responses of the rat , 1991, Pharmacology Biochemistry and Behavior.

[78]  G. Halliday,et al.  Cytoarchitecture of the human dorsal raphe nucleus , 1990, The Journal of comparative neurology.

[79]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[80]  Liesbeth Reneman,et al.  UvA-DARE ( Digital Academic Repository ) Pharmacological MRI in the assessment of monoaminergic function , 2013 .

[81]  Tsuneyuki Yamamoto,et al.  A Cannabinoid CB1 Receptor Antagonist Ameliorates Impairment of Recognition Memory on Withdrawal from MDMA (Ecstasy) , 2010, Neuropsychopharmacology.

[82]  L. Acsády,et al.  Models, structure, function: the transformation of cortical signals in the dentate gyrus. , 2007, Progress in brain research.

[83]  W. Liang,et al.  TM4 microarray software suite. , 2006, Methods in enzymology.

[84]  W. Liang,et al.  9) TM4 Microarray Software Suite , 2006 .

[85]  A. Bond,et al.  Angry cognitive bias, trait aggression and impulsivity in substance users , 2004, Psychopharmacology.

[86]  Alex E. Lash,et al.  Gene Expression Omnibus: NCBI gene expression and hybridization array data repository , 2002, Nucleic Acids Res..

[87]  B. Kosofsky,et al.  The serotoninergic innervation of cerebral cortex: Different classes of axon terminals arise from dorsal and median raphe nuclei , 1987, Synapse.

[88]  G. Paxinos.  The Rat nervous system , 1985 .

[89]  G. Paxinos,et al.  The Rat Brain in Stereotaxic Coordinates , 1983 .

[90]  T. Vitalis,et al.  Molecular and Developmental Neuroscience , 2022 .

[91]  M. Dunning,et al.  BIOINFORMATICS APPLICATIONS NOTE doi:10.1093/bioinformatics/btm311 Genome analysis beadarray: R classes and methods for Illumina bead-based data , 2022 .