Cooperative interactions at the SLP‐76 complex are critical for actin polymerization

[1]  P. Brown,et al.  Characterizing Protein‐Protein Interactions by Sedimentation Velocity Analytical Ultracentrifugation , 2008, Current protocols in immunology.

[2]  J. Burkhardt,et al.  The actin cytoskeleton in T cell activation. , 2008, Annual review of immunology.

[3]  K. Nichols,et al.  Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76. , 2008, Immunity.

[4]  Michael Loran Dustin.  T‐cell activation through immunological synapses and kinapses , 2008, Immunological reviews.

[5]  P. Leibson,et al.  Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse. , 2007, Immunity.

[6]  P. Schwartzberg.  Formin the way. , 2007, Immunity.

[7]  D. Billadeau,et al.  Regulation of T-cell activation by the cytoskeleton , 2007, Nature Reviews Immunology.

[8]  E. Appella,et al.  Studying multisite binary and ternary protein interactions by global analysis of isothermal titration calorimetry data in SEDPHAT: Application to adaptor protein complexes in cell signaling , 2007, Protein science : a publication of the Protein Society.

[9]  J. Ladbury.  Measurement of the formation of complexes in tyrosine kinase-mediated signal transduction , 2006, Acta crystallographica. Section D, Biological crystallography.

[10]  D. Billadeau,et al.  Regulation of Cytoskeletal Dynamics at the Immune Synapse: New Stars Join the Actin Troupe , 2006, Traffic.

[11]  Xiaoqian Wang,et al.  The ADAP/SKAP55 Signaling Module Regulates T-Cell Receptor-Mediated Integrin Activation through Plasma Membrane Targeting of Rap1 , 2006, Molecular and Cellular Biology.

[12]  Alex Braiman,et al.  Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1 , 2006, Nature Structural &Molecular Biology.

[13]  David J Rawlings,et al.  HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse. , 2006, Immunity.

[14]  T. Jin,et al.  Fluorescence resonance energy transfer in living cells reveals dynamic membrane changes in the initiation of B cell signaling. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[15]  L. Samelson,et al.  Recruitment and activation of PLCγ1 in T cells: a new insight into old domains , 2006 .

[16]  P. Schwartzberg,et al.  Functional Hierarchy of the N-Terminal Tyrosines of SLP-761 , 2006, The Journal of Immunology.

[17]  B. Freedman,et al.  The WAVE2 Complex Regulates Actin Cytoskeletal Reorganization and CRAC-Mediated Calcium Entry during T Cell Activation , 2006, Current Biology.

[18]  P. Zipfel,et al.  Role for the Abi/Wave Protein Complex in T Cell Receptor-Mediated Proliferation and Cytoskeletal Remodeling , 2006, Current Biology.

[19]  V. Tybulewicz,et al.  Vav-family proteins in T-cell signalling. , 2005, Current opinion in immunology.

[20]  Dvora Beach,et al.  T Cell Receptor-induced Activation of Phospholipase C-γ1 Depends on a Sequence-independent Function of the P-I Region of SLP-76* , 2005, Journal of Biological Chemistry.

[21]  Horst Wallrabe,et al.  Imaging protein molecules using FRET and FLIM microscopy. , 2005, Current opinion in biotechnology.

[22]  N. Caplen,et al.  Kinase-Independent Functions for Itk in TCR-Induced Regulation of Vav and the Actin Cytoskeleton1 , 2005, The Journal of Immunology.

[23]  R. Mariuzza,et al.  Studying multiprotein complexes by multisignal sedimentation velocity analytical ultracentrifugation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[24]  G. Koretzky,et al.  The SLP-76 family of adapter proteins. , 2004, Seminars in immunology.

[25]  E. Appella,et al.  Binding specificity of multiprotein signaling complexes is determined by both cooperative interactions and affinity preferences. , 2004, Biochemistry.

[26]  A. Laurence,et al.  Identification of pro‐interleukin 16 as a novel target of MAP kinases in activated T lymphocytes , 2004, European journal of immunology.

[27]  Michael Way,et al.  SLP-76 Coordinates Nck-Dependent Wiskott-Aldrich Syndrome Protein Recruitment with Vav-1/Cdc42-Dependent Wiskott-Aldrich Syndrome Protein Activation at the T Cell-APC Contact Site 1 , 2003, The Journal of Immunology.

[28]  D. Alexander,et al.  Approaches to Define Antigen Receptor-induced Serine Kinase Signal Transduction Pathways* , 2003, The Journal of Biological Chemistry.

[29]  L. Samelson,et al.  All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton , 2003, Immunological reviews.

[30]  J. Clements.  Known and potential functions for the SLP‐76 adapter protein in regulating T‐cell activation and development , 2003, Immunological reviews.

[31]  Tetsuo Yamazaki,et al.  T cell receptor ligation induces the formation of dynamically regulated signaling assemblies , 2002, The Journal of cell biology.

[32]  A. Duncan,et al.  Pleiotropic defects in TCR signaling in a Vav‐1‐null Jurkat T‐cell line , 2002, The EMBO journal.

[33]  L. Buday,et al.  The Nck family of adapter proteins: regulators of actin cytoskeleton. , 2002, Cellular signalling.

[34]  D. Kioussis,et al.  Vav1 Transduces T Cell Receptor Signals to the Activation of Phospholipase C-γ1 via Phosphoinositide 3-Kinase-dependent and -independent Pathways , 2002, The Journal of experimental medicine.

[35]  R. Tsien,et al.  Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells , 2002, Science.

[36]  D. Schafer,et al.  Coupling actin dynamics and membrane dynamics during endocytosis. , 2002, Current opinion in cell biology.

[37]  K. Siminovitch,et al.  The Intersectin 2 Adaptor Links Wiskott Aldrich Syndrome Protein (WASp)-mediated Actin Polymerization to T Cell Antigen Receptor Endocytosis , 2001, The Journal of experimental medicine.

[38]  Gerra L. Bosco,et al.  Wasp recruitment to the T cell:APC contact site occurs independently of Cdc42 activation. , 2001, Immunity.

[39]  Kenji Ogura,et al.  Novel recognition mode between Vav and Grb2 SH3 domains , 2001, The EMBO journal.

[40]  L. Samelson,et al.  Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. , 2001, Immunity.

[41]  A. Weiss,et al.  Signal transduction by the TCR for antigen. , 2000, Current opinion in immunology.

[42]  M. Yaffe,et al.  Biochemical Interactions Integrating Itk with the T Cell Receptor-initiated Signaling Cascade* , 2000, The Journal of Biological Chemistry.

[43]  Julian Downward,et al.  Association of Nck with tyrosine‐phosphorylated SLP‐76 in activated T lymphocytes , 1999, European journal of immunology.

[44]  B. Mayer,et al.  Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76. , 1998, Immunity.

[45]  A. Weiss,et al.  Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell. , 1998, Science.

[46]  L. Samelson,et al.  LAT The ZAP-70 Tyrosine Kinase Substrate that Links T Cell Receptor to Cellular Activation , 1998, Cell.

[47]  C. Rudd,et al.  Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2. , 1997, Immunity.

[48]  G. Koretzky,et al.  Tyrosines 113, 128, and 145 of SLP-76 are required for optimal augmentation of NFAT promoter activity. , 1996, Journal of immunology.

[49]  J. Wu,et al.  Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. , 1996, Immunity.

[50]  K. Takase,et al.  [T cell activation]. , 1995, Ryumachi. [Rheumatism].

[51]  D. Baltimore,et al.  Binding of Vav to Grb2 through dimerization of Src homology 3 domains. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[52]  Shiro Suetsugu,et al.  The WASP–WAVE protein network: connecting the membrane to the cytoskeleton , 2007, Nature Reviews Molecular Cell Biology.

[53]  G. Koretzky,et al.  SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond , 2006, Nature Reviews Immunology.

[54]  L. Samelson,et al.  Recruitment and activation of PLCgamma1 in T cells: a new insight into old domains. , 2006, The EMBO journal.

[55]  V. Barr,et al.  Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton , 2005, Nature Immunology.

[56]  K. Siminovitch,et al.  The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse. , 2003, Immunity.