Comparative gene-expression analysis.

The study of differences in gene-expression patterns is one of the most promising approaches for understanding mechanisms of differentiation and development. In addition, the identification of disease-related target molecules opens new avenues for rational pharmaceutical intervention. Recent technical advances and improvements are accelerating the analysis of gene-expression profiles at the transcript level. The knowledge and comprehension of currently applied methods is one of the central criteria for an efficient and successful gene-screening approach.

[1]  M Hubank,et al.  Identifying differences in mRNA expression by representational difference analysis of cDNA. , 1994, Nucleic acids research.

[2]  A. Pardee,et al.  Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. , 1992, Science.

[3]  R. Hardison,et al.  The isolation of structural genes from libraries of eucaryotic DNA , 1978, Cell.

[4]  J. Feramisco,et al.  Identification of ErbB3-stimulated genes using modified representational difference analysis. , 1997, The Biochemical journal.

[5]  J. Hoheisel Oligomer-chip technology , 1997 .

[6]  D. Batlle,et al.  Representational difference analysis of cDNA of genes expressed in embryonic kidney. , 1997, Kidney international.

[7]  M. Wigler,et al.  Cloning the differences between two complex genomes , 1993, Science.

[8]  Mark M. Davis,et al.  Isolation of cDNA clones encoding T cell-specific membrane-associated proteins , 1984, Nature.

[9]  K. Kinzler,et al.  Serial Analysis of Gene Expression , 1995, Science.

[10]  Michael J. O'Neill,et al.  Isolation of rare transcripts by representational difference analysis , 1997, Nucleic Acids Res..

[11]  S. P. Fodor,et al.  Multiplexed biochemical assays with biological chips , 1993, Nature.

[12]  W. Blackstock,et al.  Proteome research: Complementarity and limitations with respect to the RNA and DNA worlds , 1997, Electrophoresis.

[13]  Ronald W. Davis,et al.  Isolation of galactose-inducible DNA sequences from Saccharomyces cerevisiae by differential plaque filter hybridization , 1979, Cell.

[14]  H. Friess,et al.  Identification of genes with specific expression in pancreatic cancer by cDNA representational difference analysis , 1997, Genes, chromosomes & cancer.

[15]  A. Kerlavage,et al.  Complementary DNA sequencing: expressed sequence tags and human genome project , 1991, Science.

[16]  K. Kinzler,et al.  A model for p53-induced apoptosis , 1997, Nature.

[17]  James L. Winkler,et al.  Accessing Genetic Information with High-Density DNA Arrays , 1996, Science.

[18]  Ronald W. Davis,et al.  Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray , 1995, Science.

[19]  P. Sharp,et al.  Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids , 1977, Cell.

[20]  T. Ito,et al.  Fluorescent differential display. , 1997, Methods in molecular biology.