A bitter diterpenoid furanolactone columbin from Calumbae Radix inhibits azoxymethane-induced rat colon carcinogenesis.

[1]  J. Potter,et al.  Vegetables, fruit, and cancer. II. Mechanisms , 1991, Cancer Causes & Control.

[2]  J. Potter,et al.  Vegetables, fruit, and cancer. I. Epidemiology , 1991, Cancer Causes & Control.

[3]  E. Fiala,et al.  Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol. , 2001, Cancer research.

[4]  Takuji Tanaka,et al.  Inhibition of azoxymethane-induced colon carcinogenesis in male F344 rats by the citrus limonoids obacunone and limonin. , 2001, Carcinogenesis.

[5]  A. Murakami,et al.  Prevention of colonic aberrant crypt foci by dietary feeding of garcinol in male F344 rats. , 2000, Carcinogenesis.

[6]  M. Squires,et al.  Blocking and suppressing mechanisms of chemoprevention by dietary constituents. , 2000, Toxicology letters.

[7]  A. Hara,et al.  Modifying effects of a flavonoid morin on azoxymethane-induced large bowel tumorigenesis in rats. , 1999, Carcinogenesis.

[8]  A. Hara,et al.  Control of cell proliferation in cancer prevention. , 1999, Mutation research.

[9]  S. Vimala,et al.  Anti-tumour promoter activity in Malaysian ginger rhizobia used in traditional medicine , 1999, British Journal of Cancer.

[10]  N. Seiler,et al.  Polyamine metabolism as target for cancer chemoprevention (review). , 1998, International journal of oncology.

[11]  H. Tsuda,et al.  Chronically elevated proliferation as a risk factor for neoplasia. , 1998, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

[12]  T. Tanaka,et al.  Chemoprevention of human cancer: biology and therapy. , 1997, Critical reviews in oncology/hematology.

[13]  J. Elias,et al.  Cell proliferation indexes: a biomarker in solid tumors. , 1997, Biotechnic & histochemistry : official publication of the Biological Stain Commission.

[14]  T. Tanaka,et al.  Effect of diet on human carcinogenesis. , 1997, Critical reviews in oncology/hematology.

[15]  K. Wada,et al.  Columbin isolated from calumbae radix affects the sleeping time of anesthetized mice. , 1995, Biological & pharmaceutical bulletin.

[16]  A. Hara,et al.  Modifying effects of naturally occurring products on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats. , 1995, Cancer research.

[17]  L. Shantz,et al.  Ornithine decarboxylase as a target for chemoprevention , 1995, Journal of cellular biochemistry. Supplement.

[18]  M. Suzui,et al.  Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid: suppressing effects on tumor development and biomarkers expression of colon tumorigenesis. , 1993, Cancer research.

[19]  Takuji Tanaka,et al.  Modifying Effects of Fungal and Herb Metabolites on Azoxymethane‐induced Intestinal Carcinogenesis in Rats , 1992, Japanese journal of cancer research : Gann.

[20]  G. Block,et al.  Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. , 1992, Nutrition and cancer.

[21]  C. S. Yang,et al.  Inhibition of cytochrome P-450 2E1 by diallyl sulfide and its metabolites. , 1991, Chemical research in toxicology.

[22]  C. S. Yang,et al.  Effects of disulfiram on hepatic P450IIE1, other microsomal enzymes, and hepatotoxicity in rats. , 1991, Toxicology and applied pharmacology.

[23]  S. Winawer,et al.  Primary prevention of colorectal cancer. The WHO Collaborating Centre for the Prevention of Colorectal Cancer. , 1990, Bulletin of the World Health Organization.

[24]  Y. Shiozaki,et al.  Comparison of the effects of various inducers on 7-alkoxycoumarin O-dealkylase activities in liver microsomes. , 1989, Japanese journal of pharmacology.

[25]  K. Nishioka,et al.  POLYAMINES IN BLOOD-CELLS AS A CANCER MARKER , 1979, The Lancet.

[26]  J. Ward.  Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats. , 1974, Laboratory investigation; a journal of technical methods and pathology.

[27]  V. Aa,et al.  Letter: Nutritional muscular dystrophy and human myocardial infarction. , 1973 .