International Consensus Group on the evidence-based pharmacologic treatment of bipolar I and II depression.

In 2004, an International Consensus Group (ICG) developed and published recommendations for the treatment of bipolar I depression based on available clinical evidence. The ICG reconvened in October 2007 to reevaluate clinical trial data published in the intervening years on the treatment of bipolar I depression. In addition, the ICG extended the scope of its discussions to consider published evidence for the treatment of bipolar II depression and also special populations of patients with bipolar depression. As in 2004, the ICG agreed that these recommendations should be based on the available clinical evidence rather than expert opinion, in order to encompass all pharmacologic agents that have been evaluated for the treatment of bipolar depression.

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