Ciclopirox 1% shampoo is a safe and effective treatment for seborrheic dermatitis

Seborrheic dermatitis is a common inflammatory skin disorder characterized by red, flaking, greasy-looking patches of skin located on the scalp, nasolabial folds, eyebrows, ears and chest. These sites are sebum-rich, which support the growth of the lipophilic yeast Malassezia , an organism believed to play a causal role in seborrheic dermatitis. Ciclopirox is a potent antifungal drug with strong activity against Malassezia species, other yeasts, dermatophytes, some nondermatophytes, molds, and other organisms. Thus, ciclopirox in a shampoo formulation is an ideal treatment option for seborrheic dermatitis of the scalp. In the first article of this supplement, Gupta and Plott 1