Structure and properties of lipid A — A component of Gram-negative bacteria

[1]  K. Possinger,et al.  Preliminary study on administration of high-titer lipid A antibody serum in sepsis and septic shock patients , 1985, Infection.

[2]  V. I. Gorbach,et al.  D-3-Dodecanoyltetradecanoic acid as a constituent of lipid A from the lipopolysaccharide ofYersinia pseudotuberculosis , 1984, Experientia.

[3]  W. Marget,et al.  Lipid a antibody determinations using ELISA on patients at a children's hospital: A preliminary report , 1983, Infection.

[4]  E. N. Wardle.  The importance of anti-lipid A (anti-endotoxin): Prevention of “shock lung” and acute renal failure , 1982, World Journal of Surgery.

[5]  E. Rietschel,et al.  Lipid A, the lipid component of bacterial lipopolysaccharides: Relation of chemical structure to biological activity , 1982, Klinische Wochenschrift.

[6]  E. N. Wardle,et al.  Anti-endotoxin (anti-lipid-A) antibodies , 1980, Experientia.

[7]  W. Marget,et al.  Lipoid-A-Antikörpertiter bei Morbus Crohn , 1976, Klinische Wochenschrift.

[8]  J. Imhoff,et al.  Chemical composition of the lipopolysaccharides of Rhodobacter sulfidophilus, Rhodopseudomonas acidophila, and Rhodopseudomonas blastica , 1985, Archives of Microbiology.

[9]  K. Takayama,et al.  Preparation and antitumor activity of nontoxic lipid A , 1982, Cancer Immunology, Immunotherapy.

[10]  J. Weckesser,et al.  Chemical structure and biological activities of lipid A's from various bacterial families , 1978, Naturwissenschaften.

[11]  R. Roos,et al.  Relevance of vesico-ureteric reflux in development of lipid a antibodies in recurrent urinary tract infections in children — a preliminary study , 2004, European Journal of Pediatrics.

[12]  R. Munford,et al.  Dephosphorylation of the lipid A moiety of Escherichia coli lipopolysaccharide by mouse macrophages , 1987, Infection and immunity.

[13]  D. Dunn,et al.  Isolation and characterization of murine monoclonal antibodies specific for gram-negative bacterial lipopolysaccharide: association of cross-genus reactivity with lipid A specificity , 1987, Infection and immunity.

[14]  R. Chaby,et al.  Antigenic determinants of lipid A analyzed with synthetic models and monoclonal antibodies. , 1987, Biochemical and biophysical research communications.

[15]  T. Ogawa,et al.  Requirement of a properly acylated beta(1-6)-D-glucosamine disaccharide bisphosphate structure for efficient manifestation of full endotoxic and associated bioactivities of lipid A , 1987, Infection and immunity.

[16]  A. Horn,et al.  Lipid‐A‐Antibodies–Indicators for the Risk of Renal Scarring in Children with Urinary Tract Infection , 1986, Acta paediatrica Scandinavica.

[17]  C. Galanos,et al.  Biological activity of synthetic heptaacyl lipid A representing a component of Salmonella minnesota R595 lipid A. , 1986, European journal of biochemistry.

[18]  C. Holmes,et al.  Effect of monophosphoryl lipid A on host resistance to bacterial infection , 1986, Infection and immunity.

[19]  F. Pearson,et al.  Establishment of beta-hydroxy fatty acids as chemical marker molecules for bacterial endotoxin by gas chromatography-mass spectrometry , 1986, Applied and environmental microbiology.

[20]  C. Raetz,et al.  Protection of Mice against Lethal Endotoxemia by a Lipid A Precursor , 1986, Infection and immunity.

[21]  T. MacVittie,et al.  Radioprotective properties of detoxified lipid A from Salmonella minnesota R595. , 1986, Radiation research.

[22]  I. Mattsby‐Baltzer,et al.  Heterogeneity of lipid A: structural determination by 13C and 31P NMR of lipid A fractions from lipopolysaccharide of Escherichia coli 0111. , 1986, Biochemistry.

[23]  L. Phillips,et al.  Identification of ester-linked fatty acids of bacterial endotoxins by negative ion fast atom bombardment mass spectrometry. , 1986, Analytical biochemistry.

[24]  S. Kusumoto,et al.  Synthetic Salmonella-type lipid A antigen with high serological specificity , 1986, Infection and immunity.

[25]  W. Brehmer,et al.  Immunobiological activities of nontoxic lipid A: enhancement of nonspecific resistance in combination with trehalose dimycolate against viral infection and adjuvant effects. , 1986, International journal of immunopharmacology.

[26]  C. Raetz,et al.  Location of polar substituents and fatty acyl chains on lipid A precursors from a 3-deoxy-D-manno-octulosonic acid-deficient mutant of Salmonella typhimurium. Studies by 1H, 13C, and 31P nuclear magnetic resonance. , 1985, The Journal of biological chemistry.

[27]  C. Raetz,et al.  Isolation and characterization of eight lipid A precursors from a 3-deoxy-D-manno-octylosonic acid-deficient mutant of Salmonella typhimurium. , 1985, The Journal of biological chemistry.

[28]  M. Batley,et al.  Analytical studies of lipopolysaccharide and its derivatives from Salmonella minnesota R595. III. Reappraisal of established methods , 1985 .

[29]  N. Packer,et al.  Analytical studies of lipopolysaccharide and its derivatives from Salmonella minnesota R595. I. Phosphorus magnetic resonance spectra , 1985 .

[30]  N. Packer,et al.  Analytical studies of lipopolysaccharide and its derivatives from Salmonella minnesota R595. II. Proton and carbon magnetic resonance spectra , 1985 .

[31]  P. Rice,et al.  Antigenic heterogeneity of lipid A of Haemophilus influenzae , 1985, Infection and immunity.

[32]  H. Mayer,et al.  Lipopolysaccharides from Yersinia pestis. Studies on lipid A of lipopolysaccharides I and II. , 1985, European journal of biochemistry.

[33]  T. Yasuda,et al.  Structural requirements of lipid A responsible for the functions: a study with chemically synthesized lipid A and its analogues. , 1985, Journal of biochemistry.

[34]  R. Proctor,et al.  Activation and inhibition of Limulus amebocyte lysate coagulation by chemically defined substructures of lipid A , 1985, Infection and immunity.

[35]  R. Chaby,et al.  Chemical synthesis and immunological activities of glycolipids structurally related to lipid A. , 1985, Biochemistry.

[36]  C. Galanos,et al.  Comparison of the capacity of two lipid A precursor molecules to express the local Shwartzman phenomenon , 1985, Infection and immunity.

[37]  K. Elkins,et al.  Binding activity of a murine anti-lipid A monoclonal antibody , 1985, Infection and immunity.

[38]  S. Kusumoto,et al.  In vitro antigenic reactivity of synthetic lipid A analogues as determined by monoclonal and conventional antibodies. , 1985, Biochemical and biophysical research communications.

[39]  E. Rietschel,et al.  Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities. , 1985, European journal of biochemistry.

[40]  G. Barnickel,et al.  High state of order of isolated bacterial lipopolysaccharide and its possible contribution to the permeation barrier property of the outer membrane , 1985, Journal of bacteriology.

[41]  V. Lehmann,et al.  Free flow electrophoresis as a tool for enrichment of mutants with temperature-dependent lethal mutations in lipid A synthesis. , 1985, European journal of biochemistry.

[42]  C. Galanos,et al.  Serum anti-lipid A antibodies in multiple myeloma and Waldenström's macroglobulinaemia. , 1985, Immunobiology.

[43]  B. Lindner,et al.  Structure of de-o-acylated lipopolysaccharide from the escherichia coli re mutant strain F 515 , 1985 .

[44]  C. Raetz,et al.  Macrophage activation by monosaccharide precursors of Escherichia coli lipid A. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[45]  E. Rietschel,et al.  Structural studies on the lipid A component of enterobacterial lipopolysaccharides by laser desorption mass spectrometry. Location of acyl groups at the lipid A backbone. , 1984, European journal of biochemistry.

[46]  E. Rietschel,et al.  Nature and location of amide-bound (R)-3-acyloxyacyl groups in lipid A of lipopolysaccharides from various gram-negative bacteria. , 1984, European journal of biochemistry.

[47]  K. Brandenburg,et al.  Physical aspects of structure and function of membranes made from lipopolysaccharides and free lipid A , 1984 .

[48]  J. Wiggins,et al.  Influence of fine structure of lipid A on Limulus amebocyte lysate clotting and toxic activities , 1984, Infection and immunity.

[49]  L. Anderson,et al.  A convergent approach to the synthesis of lipid A. , 1984, Reviews of infectious diseases.

[50]  D. Morrison,et al.  Selective interaction between lymphocytes and lipid A subunits in lipopolysaccharide macromolecular aggregates. , 1984, Reviews of infectious diseases.

[51]  U. Zähringer,et al.  Concepts of the chemical structure of lipid A. , 1984, Reviews of infectious diseases.

[52]  S. Kusumoto,et al.  Recent developments in the organic synthesis of lipid A in relation to biologic activities. , 1984, Reviews of infectious diseases.

[53]  C. Galanos,et al.  Immunogenic properties of lipid A. , 1984, Reviews of infectious diseases.

[54]  C. Alving,et al.  Heterogeneity of lipid A. , 1984, Reviews of infectious diseases.

[55]  M. Kern.  Selective binding of lipid A to responder and nonresponder B lymphocyte subpopulations. , 1984, Reviews of infectious diseases.

[56]  C. Raetz.  The enzymatic synthesis of lipid A: molecular structure and biologic function of monosaccharide precursors. , 1984, Reviews of infectious diseases.

[57]  C. Alving,et al.  Antibodies to lipid A: occurrence in humans. , 1984, Reviews of infectious diseases.

[58]  K. Tanamoto,et al.  Biological activities of synthetic lipid A analogs: pyrogenicity, lethal toxicity, anticomplement activity, and induction of gelation of Limulus amoebocyte lysate , 1984, Infection and immunity.

[59]  C. Raetz,et al.  The biosynthesis of gram-negative endotoxin. Formation of lipid A disaccharides from monosaccharide precursors in extracts of Escherichia coli. , 1984, The Journal of biological chemistry.

[60]  G. Schulz,et al.  Zur struktur der 3-desoxyoctulosonsäure- (KDO-) region des lipopolysaccharids von Re 595 , 1984 .

[61]  E. Rietschel,et al.  Fatty acid in lipopolysaccharides of Salmonella species grown at low temperature. Identification and position. , 2005, European journal of biochemistry.

[62]  E. Rietschel,et al.  Chemical structure of the lipid A component of the lipopolysaccharide from a Proteus mirabilis Re-mutant. , 1983, European journal of biochemistry.

[63]  J. Weckesser,et al.  Structural studies on the phosphate-free lipid A of Rhodomicrobium vannielii ATCC 17100. , 1983, European journal of biochemistry.

[64]  S. Fesik,et al.  Structure and metal-binding properties of lipopolysaccharides from heptoseless mutants of Escherichia coli studied by 13C and 31P nuclear magnetic resonance. , 1983, The Journal of biological chemistry.

[65]  C. Fenselau,et al.  Position of ester groups in the lipid A backbone of lipopolysaccharides obtained from Salmonella typhimurium. , 1983, The Journal of biological chemistry.

[66]  I. Yano,et al.  Ornithine-containing lipid of Bordetella pertussis, a new type of hemagglutinin. , 1983, European journal of biochemistry.

[67]  R. Munford,et al.  Enzymatic deacylation of the lipid A moiety of Salmonella typhimurium lipopolysaccharides by human neutrophils. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[68]  H. Mayer,et al.  Structural studies on the non-toxic lipid A from Rhodopseudomonas sphaeroides ATCC 17023. , 1983, European journal of biochemistry.

[69]  C. Raetz,et al.  Molecular requirements for B-lymphocyte activation by Escherichia coli lipopolysaccharide. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[70]  A. Kropinski,et al.  O-antigen conversion in Pseudomonas aeruginosa PAO1 by bacteriophage D3 , 1983, Journal of bacteriology.

[71]  C. Galanos,et al.  Nontoxic lipopolysaccharide from Rhodopseudomonas sphaeroides ATCC 17023 , 1983, Journal of bacteriology.

[72]  C. Raetz,et al.  Fatty acyl derivatives of glucosamine 1-phosphate in Escherichia coli and their relation to lipid A. Complete structure of A diacyl GlcN-1-P found in a phosphatidylglycerol-deficient mutant. , 1983, The Journal of biological chemistry.

[73]  M. Vaara.  Polymyxin B nonapeptide complexes with lipopolysaccharide , 1983 .

[74]  M. Caroff,et al.  Identification of 2-amino-6-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose as a major constituent of the hydrophobic region of the Bordetella pertussis endotoxin. , 1983, Carbohydrate research.

[75]  S. Fesik,et al.  Characterization of lipopolysaccharide from a heptoseless mutant of Escherichia coli by carbon 13 nuclear magnetic resonance. , 1983, The Journal of biological chemistry.

[76]  W. R. Mccabe,et al.  Immunization with rough mutants of Salmonella minnesota. IV. Protection by antisera to O and rough antigens against endotoxin. , 1983, The Journal of infectious diseases.

[77]  M. Wilson,et al.  Evidence for different requirements in physical state for the interaction of lipopolysaccharides with the classical and alternative pathways of complement. , 2005, European journal of biochemistry.

[78]  V. I. Gorbach,et al.  The application of 13C-NMR spectroscopy to study lipid A from Yersinia pseudotuberculosis lipopolysaccharide. , 2005, European journal of biochemistry.

[79]  T. Tadakuma,et al.  Biological activity of chemically synthesized analogues of lipid A. Demonstration of adjuvant effect in hapten-sensitized liposomal system. , 2005, European journal of biochemistry.

[80]  J. Cavaillon,et al.  Macrophage-dependent polyclonal activation of splenocytes by Bordetella pertussis endotoxin and its isolated polysaccharide and Lipid A regions. , 1982, Cellular immunology.

[81]  J. Parker,et al.  Sensitive assay, based on hydroxy fatty acids from lipopolysaccharide lipid A, for Gram-negative bacteria in sediments , 1982, Applied and environmental microbiology.

[82]  N. Qureshi,et al.  Purification and structural determination of nontoxic lipid A obtained from the lipopolysaccharide of Salmonella typhimurium. , 1982, The Journal of biological chemistry.

[83]  K. Kawahara,et al.  Isolation of an unusual 'lipid A' type glycolipid from Pseudomonas paucimobilis. , 1982, Biochimica et biophysica acta.

[84]  H. Formanek.  Possible Orientation of the Fatty Acid Chains in Lipopolysaccharide , 1982, Zeitschrift fur Naturforschung. Section C, Biosciences.

[85]  H. Biebl,et al.  Lipopolysaccharide with 2,3-diamino-2,3-dideoxyglucose containing lipid A in Rhodopseudomonas sulfoviridis , 1982 .

[86]  E. Rietschel,et al.  The Chemical Structure of Lipid A , 1982 .

[87]  A. Mita,et al.  Induction of splenic T cell proliferation by lipid A in mice immunized with sheep red blood cells. , 1982, Journal of immunology.

[88]  J. Homma,et al.  Essential regions of the lipopolysaccharide of Pseudomonas aeruginosa responsible for pyrogenicity and activation of the proclotting enzyme of horseshoe crabs. Comparison with antitumor, interferon-inducing and adjuvant activities. , 1982, Journal of biochemistry.

[89]  A. Mita,et al.  In vivo activation of mouse spleen lymphocytes by lipid A in carrier-free form. , 1982, Immunology.

[90]  E. Rietschel,et al.  Lipopolysaccharides of Gram-Negative Bacteria , 1982 .

[91]  E. Rietschel,et al.  Bacterial endotoxins: chemical structure, biological activity and role in septicaemia. , 1982, Scandinavian journal of infectious diseases. Supplementum.

[92]  C. Raetz,et al.  Characterization of two membrane-associated glycolipids from an Escherichia coli mutant deficient in phosphatidylglycerol. , 1981, The Journal of biological chemistry.

[93]  M. Guenounou,et al.  Characteristics of a lipid preparation (lipid A) from Haemophilus influenzae type a lipopolysaccharide , 1981, Infection and immunity.

[94]  M. Kiso,et al.  Biological activities of fundamental, carbohydrate skeleton of lipid A containing amide-linked 3-hydroxytetradecanoic acid. , 1981 .

[95]  S. Wilkinson,et al.  Lipid composition and chemotaxonomy of Pseudomonas putrefaciens (Alteromonas putrefaciens). , 1980, Journal of general microbiology.

[96]  G. Michel,et al.  Lipid A of lipopolysaccharide from Escherichia coli K12 CR34. , 1980, Biochimie.

[97]  S. Raziuddin.  STRUCTURE AND TOXICITY OF LIPID A FROM VIBRIO CHOLERAE , 1980 .

[98]  E. Rietschel,et al.  Analysis of permethylated glucosaminyl-glucosaminitol disaccharides by combined gas-liquid chromatography mass spectrometry† , 1979 .

[99]  C. Alving,et al.  Lipid A from endotoxin: antigenic activities of purified fractions in liposomes. , 1979, Journal of immunology.

[100]  E. Rietschel,et al.  Architecture of the outer membrane of Escherichia coli K12. Phase transitions of the bacteriophage K3 receptor complex. , 1979, European journal of biochemistry.

[101]  W. Reutter,et al.  Galactosamine-induced sensitization to the lethal effects of endotoxin. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[102]  S. Raziuddin.  Structure-function relationship: biological activities of the lipopolysaccharides and lipid A from Vibrio cholerae. , 1979, The Journal of infectious diseases.

[103]  H. Mayer,et al.  Lipopolysaccharides of photosynthetic prokaryotes. , 1979, Annual review of microbiology.

[104]  C. Raetz,et al.  Membrane lipid biogenesis in Escherichia coli: identification of genetic loci for phosphatidylglycerophosphate synthetase and construction of mutants lacking phosphatidylglycerol. , 1979, The Journal of biological chemistry.

[105]  H. Khorana,et al.  Structure of the lipopolysaccharide from an Escherichia coli heptose-less mutant. I. Chemical degradations and identification of products. , 1979, The Journal of biological chemistry.

[106]  J. Homma,et al.  Regions of the lipopolysaccharide of Pseudomonas aeruginosa essential for antitumor and interferon-inducing activities. , 1979, European journal of biochemistry.

[107]  V. I. Gorbach,et al.  Structural studies on the immunodominant group of lipid A from lipopolysaccharide of Yersinia pseudotuberculosis. , 1979, European Journal of Biochemistry.

[108]  I. Mattsby‐Baltzer,et al.  Lipid A and Anti-Lipid A , 1979, Infection and immunity.

[109]  C. Alving,et al.  Production of antibodies against phosphocholine, phosphatidylcholine, sphingomyelin, and lipid A by injection of liposomes containing lipid A. , 1979, Journal of immunology.

[110]  V. I. Gorbach,et al.  Studies on lipid A from Yersinia pseudotuberculosis lipopolysaccharide. Isolation and general characterization. , 1978, European journal of biochemistry.

[111]  M. Schotz,et al.  Determination of lipid A and endotoxin in serum by mass spectroscopy. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[112]  E. Rietschel,et al.  L-2-hydroxytetradecanoic acid as a constituent of Salmonella lipopolysaccharides (lipid A). , 1978, European journal of biochemistry.

[113]  E. Rietschel,et al.  Inverse relationship between the susceptibility of lipopolysaccharide (lipid A)-pretreated mice to the hypothermic and lethal effect of lipopolysaccharide , 1978, Infection and immunity.

[114]  S. Rottem,et al.  Thermal regulation of the fatty acid composition of lipopolysaccharides and phospholipids of Proteus mirabilis. , 1978, European journal of biochemistry.

[115]  R. Munson,et al.  Biosynthesis of lipid A. Enzymatic incorporation of 3-deoxy-D-mannooctulosonate into a precursor of lipid A in Salmonella typhimurium. , 1978, The Journal of biological chemistry.

[116]  R. Tharanathan,et al.  Structural studies on the D-arabinose-containing lipid A from Rhodospirillum tenue 2761. , 1978, European journal of biochemistry.

[117]  C. Galanos,et al.  Interaction of lipopolysaccharides and lipid A with complement in rats and its relation to endotoxicity , 1978, Infection and immunity.

[118]  V. Lehmann,et al.  Microheterogeneity in lipid A demonstrated by a new intermediate in the biosynthesis of 3-deozy-D-manno-octulosonic-acid--lipid A. , 1977, European journal of biochemistry.

[119]  C. Ho,et al.  Lipid A mutants of Salmonella typhimurium. Purification and characterization of a lipid A precursor produced by a mutant in 3-deoxy-D-mannooctulosonate-8-phosphate synthetase. , 1977, The Journal of biological chemistry.

[120]  V. Lehmann,et al.  Isolation, purification and properties of an intermediate in 3-deoxy-D-manno-octulosonic acid--lipid A biosynthesis. , 1977, European journal of biochemistry.

[121]  S. Hase,et al.  The chemical structure of the lipid A component of lipopolysaccharides from Chromobacterium violaceum NCTC 9694. , 1977, European journal of biochemistry.

[122]  J. Weckesser,et al.  Biological Activities of Lipopolysaccharides and Lipid A from Rhodospirillaceae , 1977, Infection and immunity.

[123]  S. Bradley,et al.  Enhanced Toxicity for Mice of Combinations of Bacterial Lipopolysaccharide and Vincristine , 1976, Antimicrobial Agents and Chemotherapy.

[124]  E. Rietschel,et al.  Isolation and analysis of the lipid A backbone. Lipid A structure of lipopolysaccharides from various bacterial groups. , 1976, European journal of biochemistry.

[125]  E. Rietschel,et al.  Methylation analysis of glucosaminitol and glucosaminyl-glucosaminitol disaccharides. Formation of 2-deoxy-2-(N-acetylacetamido)-glucitol derivatives. , 1976, European journal of biochemistry.

[126]  E. Ribi,et al.  Tumor regression caused by endotoxins and mycobacterial fractions. , 1975, Journal of the National Cancer Institute.

[127]  R L Kassel,et al.  An endotoxin-induced serum factor that causes necrosis of tumors. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[128]  M. Nakano,et al.  Adjuvant effect of lipid A obtained from Salmonella typhimurium on antibody response in mouse spleen. The role of carriers conjugated to lipid A. , 1975, Japanese journal of microbiology.

[129]  C. Lugowski,et al.  Biological properties of lipid A from Shigella sonnei. , 1974, European journal of biochemistry.

[130]  M. Wu,et al.  Isolation and characterization of lipopolysaccharide protein from Escherichia coli. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[131]  D. Morrison,et al.  Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[132]  E. Rietschel,et al.  Nature and linkages of the fatty acids present in the lipid-A component of Salmonella lipopolysaccharides. , 1972, European journal of biochemistry.

[133]  C. Galanos,et al.  Preparation and properties of antisera against the lipid-A component of bacterial lipopolysaccharides. , 1971, European journal of biochemistry.

[134]  O. Lüderitz,et al.  The linkage of phosphate groups and of 2-keto-3-deoxyoctonate to the lipid A component in a Salmonella minnesota lipopolysaccharide. , 1971, European journal of biochemistry.

[135]  Lewis Gw.  Infection of the urinary tract. , 1970 .

[136]  A. Nowotny.  Molecular aspects of endotoxic reactions. , 1969, Bacteriological reviews.

[137]  O. Westphal,et al.  Biochemical studies on lipopolysaccharides of Salmonella R mutants. 6. Investigations on the structure of the lipid A component. , 1969, European journal of biochemistry.

[138]  H. Selye,et al.  Effect of Lead Acetate on the Susceptibility of Rats to Bacterial Endotoxins , 1966, Journal of bacteriology.