Antiviral treatment with fluoxetine for rituximab‐associated chronic echovirus 13 meningoencephalitis and myofasciitis

Enterovirus infections pose a serious threat for patients with humoral deficiencies and may be lethal, whilst the efficacy of proposed treatment options such as corticosteroids, intravenous immunoglobulins and fluoxetine remains debated.

[1]  B. Coutard,et al.  Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex , 2022, Science advances.

[2]  Ronak K. Kapadia,et al.  Enterovirus A71 causing meningoencephalitis and acute flaccid myelitis in a patient receiving rituximab , 2021, Journal of Neuroimmunology.

[3]  P. Feugier,et al.  Prolonged in‐hospital stay and higher mortality after Covid‐19 among patients with non‐Hodgkin lymphoma treated with B‐cell depleting immunotherapy , 2021, American journal of hematology/oncology.

[4]  T. V. von Oertzen,et al.  Efficacy and safety of intravenous immunoglobulins for the treatment of viral encephalitis: a systematic literature review , 2021, Journal of Neurology.

[5]  P. Maes,et al.  Convalescent plasma treatment of persistent severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection in patients with lymphoma with impaired humoral immunity and lack of neutralising antibodies , 2020, British journal of haematology.

[6]  Z. Amoura,et al.  [Enteroviral infections in adults treated with rituximab: A new case of chronic meningitis and myofasciitis and literature review]. , 2020 .

[7]  T. Langer,et al.  Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner , 2019, ACS infectious diseases.

[8]  L. Hazrati,et al.  Treatment of rituximab-associated chronic CNS enterovirus using IVIg and fluoxetine , 2019, Neurology.

[9]  J. Gofshteyn,et al.  Treatment of Chronic Enterovirus Encephalitis With Fluoxetine in a Patient With X-Linked Agammaglobulinemia. , 2016, Pediatric neurology.

[10]  Ting-Yu Yen,et al.  The correlation between the presence of viremia and clinical severity in patients with enterovirus 71 infection: a multi-center cohort study , 2014, BMC Infectious Diseases.

[11]  H. Ochs,et al.  Neutralization of different echovirus serotypes by individual lots of intravenous immunoglobulin , 2011, Journal of medical virology.

[12]  A. Jenkins,et al.  Comparison of drug concentrations in postmortem cerebrospinal fluid and blood specimens. , 2007, Journal of analytical toxicology.

[13]  M Hummel,et al.  Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936 , 2003, Leukemia.

[14]  M. Fava,et al.  Accumulation of fluoxetine and norfluoxetine in human brain during therapeutic administration. , 1992, The American journal of psychiatry.