Industrial safety can be regarded as a major issue of industrial environments nowadays. This is why industries are currently spending huge amounts of resources to improve safety in all levels by reducing risks of causing damages to equipment, human injuries or even fatalities. This paper describes how Virtual Reality, Human Factors and Rule-based technologies are used in the framework of the VIRTHUALIS Integrated Project towards industrial training, safety management and accident investigation. The paper focuses mainly on the VR system specification and basic modules, while at the same time it presents the main system modules that synthesize the tool as a whole.